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Volumn 18, Issue 19, 1999, Pages 5159-5165

Ephrins and their Eph receptors: Multitalented directors of embryonic development

Author keywords

Angiogenesis; Axon guidance; Nervous system development; Topography; Tyrosins protein kinase

Indexed keywords

EPHRIN; EPHRIN RECEPTOR; PROTEIN; RECEPTOR; UNCLASSIFIED DRUG;

EID: 0033215333     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.19.5159     Document Type: Review
Times cited : (131)

References (71)
  • 1
    • 0033082959 scopus 로고    scopus 로고
    • Roles of ephrinB ligands and EphB receptors in cardiovascular development: Demarcation of arterial/venous domains, vascular morphogenesis and sprouting angiogenesis
    • Adams, R.H., Wilkinson, G.A., Weiss, C., Diella, F. Gale, N.W., Deutsch, U., Risau, W. and Klein, R. (1999) Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis and sprouting angiogenesis. Genes Dev., 13, 295-306.
    • (1999) Genes Dev. , vol.13 , pp. 295-306
    • Adams, R.H.1    Wilkinson, G.A.2    Weiss, C.3    Diella, F.4    Gale, N.W.5    Deutsch, U.6    Risau, W.7    Klein, R.8
  • 2
    • 0030221512 scopus 로고    scopus 로고
    • Similarities and differences in the way transmembrane-type ligands interact with the Elk subclass of Eph receptors
    • Brambilla, R., Brückner, K., Orioli, D., Bergemann, A.D., Flanagan, J.G. and Klein, R. (1996) Similarities and differences in the way transmembrane-type ligands interact with the Elk subclass of Eph receptors. Mol. Cell. Neurosci., 8, 199-209.
    • (1996) Mol. Cell. Neurosci. , vol.8 , pp. 199-209
    • Brambilla, R.1    Brückner, K.2    Orioli, D.3    Bergemann, A.D.4    Flanagan, J.G.5    Klein, R.6
  • 3
    • 0032103082 scopus 로고    scopus 로고
    • Signaling by Eph receptors and their ephrin ligands
    • Brückner, K. and Klein, R. (1998) Signaling by Eph receptors and their ephrin ligands. Curr. Opin. Cell Biol., 8, 375-382.
    • (1998) Curr. Opin. Cell Biol. , vol.8 , pp. 375-382
    • Brückner, K.1    Klein, R.2
  • 4
    • 0030891962 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of transmembrane ligands for eph receptors
    • Brückner, K., Pasquale, E.B. and Klein, R. (1997) Tyrosine phosphorylation of transmembrane ligands for eph receptors. Science, 275, 1640-1643.
    • (1997) Science , vol.275 , pp. 1640-1643
    • Brückner, K.1    Pasquale, E.B.2    Klein, R.3
  • 5
    • 0033103887 scopus 로고    scopus 로고
    • EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains
    • Brückner, K., Labrador, J.P., Scheiffele, P., Herb, A., Seeburg, P. and Klein, R. (1999) EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. Neuron, 22, 511-524.
    • (1999) Neuron , vol.22 , pp. 511-524
    • Brückner, K.1    Labrador, J.P.2    Scheiffele, P.3    Herb, A.4    Seeburg, P.5    Klein, R.6
  • 6
    • 0033601747 scopus 로고    scopus 로고
    • The junction-associated protein AF-6 interacts and clusters with specific eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brain
    • Buchert, M., Schneider, S., Meskenaite, V., Adams, M.T., Canaani, E., Baechi, T., Moelling, K. and Hovens, C.M. (1999) The junction-associated protein AF-6 interacts and clusters with specific eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brain. J. Cell Biol., 25, 361-371.
    • (1999) J. Cell Biol. , vol.25 , pp. 361-371
    • Buchert, M.1    Schneider, S.2    Meskenaite, V.3    Adams, M.T.4    Canaani, E.5    Baechi, T.6    Moelling, K.7    Hovens, C.M.8
  • 7
    • 0032526731 scopus 로고    scopus 로고
    • Dual action of a ligand for Eph receptor tyrosine kinases on specific populations of axons during the development of cortical circuits
    • Castellani, V., Yue, Y., Gao, P.-P., Zhou, R. and Bolz, J. (1998) Dual action of a ligand for Eph receptor tyrosine kinases on specific populations of axons during the development of cortical circuits. J. Neurosci., 18, 4663-4672.
    • (1998) J. Neurosci. , vol.18 , pp. 4663-4672
    • Castellani, V.1    Yue, Y.2    Gao, P.-P.3    Zhou, R.4    Bolz, J.5
  • 8
    • 0032544399 scopus 로고    scopus 로고
    • An enhancer element in the EphA2 (Eck) gene sufficient for rhombomere-specific expression is activated by HOXA1 and HOXB1 homeobox proteins
    • Chen, J. and Ruley, H.E. (1998) An enhancer element in the EphA2 (Eck) gene sufficient for rhombomere-specific expression is activated by HOXA1 and HOXB1 homeobox proteins. J. Biol. Chem., 273, 24670-24675.
    • (1998) J. Biol. Chem. , vol.273 , pp. 24670-24675
    • Chen, J.1    Ruley, H.E.2
  • 9
    • 0029086140 scopus 로고
    • Complementary gradients in expression and binding of Elf-1 and Mek4 in development of the topographic retinotectal projection map
    • Cheng, H.-J., Nakamoto, M., Bergemann, A.D. and Flanagan, J.G. (1995) Complementary gradients in expression and binding of Elf-1 and Mek4 in development of the topographic retinotectal projection map. Cell. 82, 371-381.
    • (1995) Cell , vol.82 , pp. 371-381
    • Cheng, H.-J.1    Nakamoto, M.2    Bergemann, A.D.3    Flanagan, J.G.4
  • 11
    • 0030221910 scopus 로고    scopus 로고
    • The Eph kinase ligand AL-1 is expressed by rostral muscles and inhibits outgrowth from caudal neurons
    • Donoghue, M.J., Lewis, R.M., Merlie, J.P. and Sanes, J.R. (1996) The Eph kinase ligand AL-1 is expressed by rostral muscles and inhibits outgrowth from caudal neurons. Mol. Cell. Neurosci., 8, 185-198.
    • (1996) Mol. Cell. Neurosci. , vol.8 , pp. 185-198
    • Donoghue, M.J.1    Lewis, R.M.2    Merlie, J.P.3    Sanes, J.R.4
  • 12
    • 13144259630 scopus 로고    scopus 로고
    • EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract
    • Dottori, M. et al. (1998) EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract. Proc. Natl Acad. Sci. USA, 95, 13248-13253.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 13248-13253
    • Dottori, M.1
  • 13
    • 0029082312 scopus 로고
    • In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases
    • Drescher, U., Kremoser, C., Handwerker, C., Löschinger, J., Noda, M. and Bonhoeffer, F. (1995) In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases. Cell, 82, 359-370.
    • (1995) Cell , vol.82 , pp. 359-370
    • Drescher, U.1    Kremoser, C.2    Handwerker, C.3    Löschinger, J.4    Noda, M.5    Bonhoeffer, F.6
  • 15
    • 0029867243 scopus 로고    scopus 로고
    • A juxtamembrane autophosphorylation site in the Eph family receptor tyrosine kinase, Sek, mediates high affinity interaction with p59fyn
    • Ellis, C., Kasmi, F., Ganju, P., Walls, E., Panayotou, G. and Reith, A.D. (1996) A juxtamembrane autophosphorylation site in the Eph family receptor tyrosine kinase, Sek, mediates high affinity interaction with p59fyn. Oncogene, 12, 1727-1736.
    • (1996) Oncogene , vol.12 , pp. 1727-1736
    • Ellis, C.1    Kasmi, F.2    Ganju, P.3    Walls, E.4    Panayotou, G.5    Reith, A.D.6
  • 16
    • 0031559401 scopus 로고    scopus 로고
    • Unified nomenclature for Eph family receptors and their ligands, the ephrins
    • Eph Nomenclature Committee (1997) Unified nomenclature for Eph family receptors and their ligands, the ephrins. Cell, 90, 403-404.
    • (1997) Cell , vol.90 , pp. 403-404
  • 18
    • 0031922119 scopus 로고    scopus 로고
    • The ephrins and Eph receptors in neural development
    • Flanagan, J.G. and Vanderhaegen, P. (1998) The ephrins and Eph receptors in neural development. Annu. Rev. Neurosci., 21, 309-345.
    • (1998) Annu. Rev. Neurosci. , vol.21 , pp. 309-345
    • Flanagan, J.G.1    Vanderhaegen, P.2
  • 19
    • 0029800030 scopus 로고    scopus 로고
    • Retroviral missexpression of engrailed genes in the chick optic tectum perturbs the topographic targeting of retinal axons
    • Friedman, G.C. and O'Leary, D.D.M. (1996) Retroviral missexpression of engrailed genes in the chick optic tectum perturbs the topographic targeting of retinal axons. J. Neurosci., 16, 5498-5509.
    • (1996) J. Neurosci. , vol.16 , pp. 5498-5509
    • Friedman, G.C.1    O'Leary, D.D.M.2
  • 21
    • 0032006223 scopus 로고    scopus 로고
    • Ephrin-A5 (AL-1/RAGS) is essential for proper retinal axon guidance and topographic mapping in the mammalian visual system
    • Frisén, J., Yates, P.A., McLaughlin, T., Friedman, G.C., O'Leary, D.D.M. and Barbacid, M. (1998b) Ephrin-A5 (AL-1/RAGS) is essential for proper retinal axon guidance and topographic mapping in the mammalian visual system. Neuron, 20, 235-243.
    • (1998) Neuron , vol.20 , pp. 235-243
    • Frisén, J.1    Yates, P.A.2    McLaughlin, T.3    Friedman, G.C.4    O'Leary, D.D.M.5    Barbacid, M.6
  • 22
    • 0030728938 scopus 로고    scopus 로고
    • Ephrins and their receptors: A repulsive topic
    • Gale, N.W. and Yancopoulos, G.D. (1997) Ephrins and their receptors: a repulsive topic. Cell Tissue Res., 290, 227-241.
    • (1997) Cell Tissue Res. , vol.290 , pp. 227-241
    • Gale, N.W.1    Yancopoulos, G.D.2
  • 23
    • 15844429889 scopus 로고    scopus 로고
    • Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis
    • Gale, N.W. et al. (1996) Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis. Neuron, 17, 9-19.
    • (1996) Neuron , vol.17 , pp. 9-19
    • Gale, N.W.1
  • 25
    • 0032574790 scopus 로고    scopus 로고
    • Regulaton of thalamic neurite outgrowth by the Eph ligand ephrin-A5: Implications in the development of thalamocortical projections
    • Gao, P.-P., Yue, Y., Zhang, J.-H., Ceretti, D.P., Levitt, P. and Zhou, R. (1998a) Regulaton of thalamic neurite outgrowth by the Eph ligand ephrin-A5: implications in the development of thalamocortical projections. Proc. Natl Acad. Sci. USA, 95, 5329-5334.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 5329-5334
    • Gao, P.-P.1    Yue, Y.2    Zhang, J.-H.3    Ceretti, D.P.4    Levitt, P.5    Zhou, R.6
  • 27
    • 0032489430 scopus 로고    scopus 로고
    • The VAB-1 Eph receptor tyrosine kinase functions in neural and epithelial morphogenesis in C. elegans
    • George, S.E., Simokat, K., Hardin, J. and Chisholm, A.D. (1998) The VAB-1 Eph receptor tyrosine kinase functions in neural and epithelial morphogenesis in C. elegans. Cell, 92, 633-643.
    • (1998) Cell , vol.92 , pp. 633-643
    • George, S.E.1    Simokat, K.2    Hardin, J.3    Chisholm, A.D.4
  • 28
    • 0029780534 scopus 로고    scopus 로고
    • A new member of the Eph family of receptors that lacks protein tyrosine kinase activity
    • Gurniak, C.B. and Berg, L.J. (1996) A new member of the Eph family of receptors that lacks protein tyrosine kinase activity. Oncogene, 13, 777-786.
    • (1996) Oncogene , vol.13 , pp. 777-786
    • Gurniak, C.B.1    Berg, L.J.2
  • 29
    • 0344816258 scopus 로고    scopus 로고
    • Nuk controls pathfinding of commissural axons in the mammalian central nervous system
    • Henkemeyer, M., Orioli, D., Henderson, J.T., Saxton, T.M., Roder, J., Pawson, T. and Klein, R. (1996) Nuk controls pathfinding of commissural axons in the mammalian central nervous system. Cell, 86, 35-46.
    • (1996) Cell , vol.86 , pp. 35-46
    • Henkemeyer, M.1    Orioli, D.2    Henderson, J.T.3    Saxton, T.M.4    Roder, J.5    Pawson, T.6    Klein, R.7
  • 30
    • 0032480889 scopus 로고    scopus 로고
    • Crystal structure of the ligand-binding domain of the receptor tyrosine kinase EphB2
    • Himanen, J.-P., Henkemeyer, M. and Nikolov, D.B. (1998) Crystal structure of the ligand-binding domain of the receptor tyrosine kinase EphB2. Nature, 396, 486-491.
    • (1998) Nature , vol.396 , pp. 486-491
    • Himanen, J.-P.1    Henkemeyer, M.2    Nikolov, D.B.3
  • 31
    • 0032537766 scopus 로고    scopus 로고
    • Tyrosine-614, the major autophosphorylation site of the receptor tyrosine kinase HEK2, functions as multi-docking site for SH′-domain mediated interactions
    • Hock, B., Böhme, B., Karn, T., Feller, S., Rubsamen-Waigmann, H. and Strebhardt, K. (1998a) Tyrosine-614, the major autophosphorylation site of the receptor tyrosine kinase HEK2, functions as multi-docking site for SH′-domain mediated interactions. Oncogene, 17, 255-260.
    • (1998) Oncogene , vol.17 , pp. 255-260
    • Hock, B.1    Böhme, B.2    Karn, T.3    Feller, S.4    Rubsamen-Waigmann, H.5    Strebhardt, K.6
  • 32
    • 13144256698 scopus 로고    scopus 로고
    • PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor
    • Hock, B. et al. (1998b) PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor. Proc. Natl Acad. Sci. USA, 95, 9779-9784.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 9779-9784
    • Hock, B.1
  • 33
    • 0029851690 scopus 로고    scopus 로고
    • Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands
    • Holland, S.J., Gale, N.W., Mbamalu, G., Yancopoulos, G.D., Henkemeyer, M. and Pawson, T. (1996) Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands. Nature, 383, 722-725.
    • (1996) Nature , vol.383 , pp. 722-725
    • Holland, S.J.1    Gale, N.W.2    Mbamalu, G.3    Yancopoulos, G.D.4    Henkemeyer, M.5    Pawson, T.6
  • 34
  • 35
    • 0033119320 scopus 로고    scopus 로고
    • Modulation of EphA receptor function by coexpressed ephrinA ligands on retinal ganglion cell axons
    • Hornberger, M.R. et al. (1999) Modulation of EphA receptor function by coexpressed ephrinA ligands on retinal ganglion cell axons. Neuron, 22, 731-742.
    • (1999) Neuron , vol.22 , pp. 731-742
    • Hornberger, M.R.1
  • 36
    • 0030067618 scopus 로고    scopus 로고
    • A role for gradient en expression in positional specification on the optic tectum
    • Itasaki, N. and Nakamura, H. (1996) A role for gradient en expression in positional specification on the optic tectum. Neuron, 16, 55-62.
    • (1996) Neuron , vol.16 , pp. 55-62
    • Itasaki, N.1    Nakamura, H.2
  • 37
    • 0027977939 scopus 로고
    • Overexpression of ERK, an EPH family receptor protein tyrosine kinase, in various human tumors
    • Kiyokawa, E. et al. (1994) Overexpression of ERK, an EPH family receptor protein tyrosine kinase, in various human tumors. Cancer Res., 54, 3645-3650.
    • (1994) Cancer Res. , vol.54 , pp. 3645-3650
    • Kiyokawa, E.1
  • 39
    • 0027953771 scopus 로고
    • Hox genes in vertbrate development
    • Krumlauf, R. (1994) Hox genes in vertbrate development. Cell, 78, 191-201.
    • (1994) Cell , vol.78 , pp. 191-201
    • Krumlauf, R.1
  • 40
    • 0030962317 scopus 로고    scopus 로고
    • The N-terminal globular domain of Eph receptors is sufficient for ligand binding and receptor signaling
    • Labrador, J.P., Brambilla, R. and Klein, R. (1997) The N-terminal globular domain of Eph receptors is sufficient for ligand binding and receptor signaling. EMBO J., 16, 3889-3897.
    • (1997) EMBO J. , vol.16 , pp. 3889-3897
    • Labrador, J.P.1    Brambilla, R.2    Klein, R.3
  • 41
    • 0032493828 scopus 로고    scopus 로고
    • Distinct subdomains of the EphA3 receptor mediate ligand binding and receptor dimerization
    • Lackmann, M. et al. (1998) Distinct subdomains of the EphA3 receptor mediate ligand binding and receptor dimerization. J. Biol. Chem., 273, 20228-20237.
    • (1998) J. Biol. Chem. , vol.273 , pp. 20228-20237
    • Lackmann, M.1
  • 42
    • 0027493163 scopus 로고
    • Biological and biochemical activities of a chimeric epidermal growth factor-elk receptor tyrosine kinase
    • Lhotak, V. and Pawson, T. (1993) Biological and biochemical activities of a chimeric epidermal growth factor-elk receptor tyrosine kinase. Mol. Cell. Biol., 13, 7071-7079.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7071-7079
    • Lhotak, V.1    Pawson, T.2
  • 43
    • 0033525063 scopus 로고    scopus 로고
    • The carboxyl terminus of B class ephrins constitutes a PDZ domain binding motif
    • Lin, D., Gish, G.D., Songyang, Z. and Pawson, T. (1999) The carboxyl terminus of B class ephrins constitutes a PDZ domain binding motif. J. Biol. Chem., 274, 3726-3733.
    • (1999) J. Biol. Chem. , vol.274 , pp. 3726-3733
    • Lin, D.1    Gish, G.D.2    Songyang, Z.3    Pawson, T.4
  • 44
    • 0030221467 scopus 로고    scopus 로고
    • Rostral optic tectum acquires caudal characteristics following ectopic Engrailed expression
    • Logan, C., Wizenmann, A., Drescher, U., Monschau, B., Bonhoeffer, F. and Lumsden, A. (1996) Rostral optic tectum acquires caudal characteristics following ectopic Engrailed expression. Curr. Biol., 6, 1006-1014.
    • (1996) Curr. Biol. , vol.6 , pp. 1006-1014
    • Logan, C.1    Wizenmann, A.2    Drescher, U.3    Monschau, B.4    Bonhoeffer, F.5    Lumsden, A.6
  • 45
    • 0031057545 scopus 로고    scopus 로고
    • AL-1-induced growth cone collapse of rat cortical neurons is correlated with REK7 expression and rearrangement of the actin cytoskeleton
    • Meima, L., Kljavin, I.J., Moran, P., Shih, A., Winslow, J.W. and Caras, I.W. (1997a) AL-1-induced growth cone collapse of rat cortical neurons is correlated with REK7 expression and rearrangement of the actin cytoskeleton. Eur. J. Neurosci., 9, 177-188.
    • (1997) Eur. J. Neurosci. , vol.9 , pp. 177-188
    • Meima, L.1    Kljavin, I.J.2    Moran, P.3    Shih, A.4    Winslow, J.W.5    Caras, I.W.6
  • 46
    • 0030833727 scopus 로고    scopus 로고
    • Lerk2 (ephrin-B1) is a collapsing factor for a subset of cortical growth cones and acts by a mechanism different from AL-1 (ephrin-A5)
    • Meima, L., Moran, P., Matthews, W. and Caras, I.W. (1997b) Lerk2 (ephrin-B1) is a collapsing factor for a subset of cortical growth cones and acts by a mechanism different from AL-1 (ephrin-A5). Mol Cell. Neurosci., 9, 314-328.
    • (1997) Mol Cell. Neurosci. , vol.9 , pp. 314-328
    • Meima, L.1    Moran, P.2    Matthews, W.3    Caras, I.W.4
  • 47
    • 0033168047 scopus 로고    scopus 로고
    • Eph receptors and ephrins restrict cell intermingling and communication
    • Mellitzer, G., Xu, Q. and Wilkinson, D.G. (1999) Eph receptors and ephrins restrict cell intermingling and communication. Nature, 400, 77-81.
    • (1999) Nature , vol.400 , pp. 77-81
    • Mellitzer, G.1    Xu, Q.2    Wilkinson, D.G.3
  • 48
    • 0031003116 scopus 로고    scopus 로고
    • Shared and unique functions of RAGS and ELF-1 in guiding retinal axons
    • Monschau, B. et al. (1997) Shared and unique functions of RAGS and ELF-1 in guiding retinal axons. EMBO J., 16, 1258-1267.
    • (1997) EMBO J. , vol.16 , pp. 1258-1267
    • Monschau, B.1
  • 50
    • 0029858435 scopus 로고    scopus 로고
    • Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation
    • Orioli, D., Henkemeyer, M., Lemke, G., Klein, R. and Pawson, T. (1996) Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J., 15, 6035-6049.
    • (1996) EMBO J. , vol.15 , pp. 6035-6049
    • Orioli, D.1    Henkemeyer, M.2    Lemke, G.3    Klein, R.4    Pawson, T.5
  • 51
    • 0028104680 scopus 로고
    • Activation of the Eck receptor protein tyrosine kinase stimulates phosphatidylinositol 3-kinase activity
    • Pandey, A., Lazar, D.F., Saltiel, A.R. and Dixit, V.M. (1994) Activation of the Eck receptor protein tyrosine kinase stimulates phosphatidylinositol 3-kinase activity. J. Biol. Chem., 269, 30154-30157.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30154-30157
    • Pandey, A.1    Lazar, D.F.2    Saltiel, A.R.3    Dixit, V.M.4
  • 52
    • 0029095073 scopus 로고
    • Characterization of a novel Src-like adapter protein that associates with the Eck receptor tyrosine kinase
    • Pandey, A., Duan, H. and Dixit, V.M. (1995a) Characterization of a novel Src-like adapter protein that associates with the Eck receptor tyrosine kinase. J. Biol. Chem., 270, 19201-19204.
    • (1995) J. Biol. Chem. , vol.270 , pp. 19201-19204
    • Pandey, A.1    Duan, H.2    Dixit, V.M.3
  • 53
    • 0029036501 scopus 로고
    • Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-α-induced angiogenesis
    • Pandey, A., Shao, H., Marks, R.M., Polverini, P.J. and Dixit, V.M. (1995b) Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-α-induced angiogenesis. Science, 268, 567-569.
    • (1995) Science , vol.268 , pp. 567-569
    • Pandey, A.1    Shao, H.2    Marks, R.M.3    Polverini, P.J.4    Dixit, V.M.5
  • 54
    • 0030957996 scopus 로고    scopus 로고
    • Aberrant axonal projections in mice lacking EphA8 (Eek) tyrosine protein kinase receptors
    • Park, S., Frisén, J. and Barbacid, M. (1997) Aberrant axonal projections in mice lacking EphA8 (Eek) tyrosine protein kinase receptors. EMBO J., 16, 3106-3114.
    • (1997) EMBO J. , vol.16 , pp. 3106-3114
    • Park, S.1    Frisén, J.2    Barbacid, M.3
  • 55
    • 0030937599 scopus 로고    scopus 로고
    • En-2 regulates the expression of the ligands for Eph type tyrosine kinases in chick embryonic tectum
    • Shigetani, Y., Funahashi, J.I. and Nakamura, H. (1997) En-2 regulates the expression of the ligands for Eph type tyrosine kinases in chick embryonic tectum. Neurosci. Res., 27, 211-217.
    • (1997) Neurosci. Res. , vol.27 , pp. 211-217
    • Shigetani, Y.1    Funahashi, J.I.2    Nakamura, H.3
  • 56
    • 0031213749 scopus 로고    scopus 로고
    • The EphA4 and EphB1 receptor tyrosine kinases and ephrin-B2 ligand regulate targeted migration of branchial neural crest cells
    • Smith, A., Robinson, V., Patel, K. and Wilkinson, D.G. (1997) The EphA4 and EphB1 receptor tyrosine kinases and ephrin-B2 ligand regulate targeted migration of branchial neural crest cells. Curr. Biol., 7, 561-570.
    • (1997) Curr. Biol. , vol.7 , pp. 561-570
    • Smith, A.1    Robinson, V.2    Patel, K.3    Wilkinson, D.G.4
  • 57
    • 78651127719 scopus 로고
    • Chemoaffinity in the orderly growth of nerve fiber patterns and connections
    • Sperry, R.W. (1963) Chemoaffinity in the orderly growth of nerve fiber patterns and connections. Proc. Natl Acad. Sci. USA, 50, 703-710.
    • (1963) Proc. Natl Acad. Sci. USA , vol.50 , pp. 703-710
    • Sperry, R.W.1
  • 58
    • 0029813872 scopus 로고    scopus 로고
    • Ligand activation of Elk receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells
    • Stein, E., Ceretti, D.P. and O'Daniel, T.O. (1996) Ligand activation of Elk receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells. J. Biol. Chem., 271, 23588-23593.
    • (1996) J. Biol. Chem. , vol.271 , pp. 23588-23593
    • Stein, E.1    Ceretti, D.P.2    O'Daniel, T.O.3
  • 59
    • 0032031705 scopus 로고    scopus 로고
    • Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment and assembly responses
    • Stein, E., Lane, A.A., Cerretti, D.P, Schoecklmann, H.O., Schroff, A.D., Van Etten, R.L. and Daniel, T.O. (1998) Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment and assembly responses. Genes Dev. 12, 667-678.
    • (1998) Genes Dev. , vol.12 , pp. 667-678
    • Stein, E.1    Lane, A.A.2    Cerretti, D.P.3    Schoecklmann, H.O.4    Schroff, A.D.5    Van Etten, R.L.6    Daniel, T.O.7
  • 60
    • 0031894510 scopus 로고    scopus 로고
    • Genetic interactions between Hoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning
    • Studer, M., Gavalas, A., Marshall, H., Ariza-McNaughton, L., Rijli, F.M., Chambon, P. and Krumlauf, R. (1998) Genetic interactions between Hoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning. Development, 125, 1025-1036.
    • (1998) Development , vol.125 , pp. 1025-1036
    • Studer, M.1    Gavalas, A.2    Marshall, H.3    Ariza-McNaughton, L.4    Rijli, F.M.5    Chambon, P.6    Krumlauf, R.7
  • 61
    • 0030221204 scopus 로고    scopus 로고
    • The expression pattern of the mouse receptor tyrosine kinase gene Mdk1 is conserved through evolution and requires Hoxa-2 for rhombomere-specific expression in mouse embryos
    • Taneja, R., Thisse, B., Rijli, F.M., Thisse, C., Bouillet, P., Dolle, P. and Chambon, P. (1996) The expression pattern of the mouse receptor tyrosine kinase gene Mdk1 is conserved through evolution and requires Hoxa-2 for rhombomere-specific expression in mouse embryos. Dev. Biol., 177, 397-412.
    • (1996) Dev. Biol. , vol.177 , pp. 397-412
    • Taneja, R.1    Thisse, B.2    Rijli, F.M.3    Thisse, C.4    Bouillet, P.5    Dolle, P.6    Chambon, P.7
  • 62
    • 0029164630 scopus 로고
    • Eph receptor tyrosine kinases, axon repulsion and the development of topographic maps
    • Tessier-Lavigne, M. (1995) Eph receptor tyrosine kinases, axon repulsion and the development of topographic maps. Cell, 82, 345-348.
    • (1995) Cell , vol.82 , pp. 345-348
    • Tessier-Lavigne, M.1
  • 63
    • 0031952696 scopus 로고    scopus 로고
    • Segmental expression of the EphA4 (Sek-1) receptor tyrosine kinase in the hindbrain is under direct transcriptional control of Krox-20
    • Theil, T., Frain, M., Gilardi-Hebenstreit, P., Flenniken, A., Charnay, P. and Wilkinson, D.G. (1998) Segmental expression of the EphA4 (Sek-1) receptor tyrosine kinase in the hindbrain is under direct transcriptional control of Krox-20. Development, 125, 443-452.
    • (1998) Development , vol.125 , pp. 443-452
    • Theil, T.1    Frain, M.2    Gilardi-Hebenstreit, P.3    Flenniken, A.4    Charnay, P.5    Wilkinson, D.G.6
  • 65
    • 0023607412 scopus 로고
    • Recognition of position-specific properties of tectal cell membranes by retinal axons in vitro
    • Walter, J., Kern-Veits, B., Huf, J., Stolze, B. and Bonhoeffer, F. (1987) Recognition of position-specific properties of tectal cell membranes by retinal axons in vitro. Development, 101, 685-696.
    • (1987) Development , vol.101 , pp. 685-696
    • Walter, J.1    Kern-Veits, B.2    Huf, J.3    Stolze, B.4    Bonhoeffer, F.5
  • 66
    • 0030890656 scopus 로고    scopus 로고
    • Eph family transmembrane ligands can mediate repulsive guidance of trunk neural crest migration and motor axon outgrowth
    • Wang, H.U. and Anderson, D.J. (1997) Eph family transmembrane ligands can mediate repulsive guidance of trunk neural crest migration and motor axon outgrowth. Neuron, 18, 383-396.
    • (1997) Neuron , vol.18 , pp. 383-396
    • Wang, H.U.1    Anderson, D.J.2
  • 67
    • 0032577446 scopus 로고    scopus 로고
    • Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4
    • Wang, H.U., Chen, Z.-F. and Anderson, D.J. (1998) Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell, 93, 741-753.
    • (1998) Cell , vol.93 , pp. 741-753
    • Wang, H.U.1    Chen, Z.-F.2    Anderson, D.J.3
  • 68
    • 0028989595 scopus 로고
    • Cloning of AL-1. a ligand for an eph-related tyrosine kinase receptor involved in axon bundle formation
    • Winslow, J.W. et al. (1995) Cloning of AL-1. a ligand for an eph-related tyrosine kinase receptor involved in axon bundle formation. Neuron, 14, 973-981.
    • (1995) Neuron , vol.14 , pp. 973-981
    • Winslow, J.W.1
  • 69
    • 13344261393 scopus 로고
    • Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain
    • Xu, Q., Alldus, G., Holder, N. and Wilkinson, D.G. (1995) Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain. Development, 121, 4005-4016.
    • (1995) Development , vol.121 , pp. 4005-4016
    • Xu, Q.1    Alldus, G.2    Holder, N.3    Wilkinson, D.G.4
  • 70
    • 0033587129 scopus 로고    scopus 로고
    • In vivo cell sorting in complementary segmental domains mediated by Eph receptors and ephrins
    • Xu, Q., Mellitzer, G., Robinson, V. and Wilkinson, D.G. (1999) In vivo cell sorting in complementary segmental domains mediated by Eph receptors and ephrins. Nature, 399, 267-271.
    • (1999) Nature , vol.399 , pp. 267-271
    • Xu, Q.1    Mellitzer, G.2    Robinson, V.3    Wilkinson, D.G.4
  • 71
    • 0033559449 scopus 로고    scopus 로고
    • Specification of distinct dopaminergic neural pathways: Roles of the Eph family receptor EphB1 and ligand ephrin-B2
    • Yue, Y., Widmer, D.A.J., Halladay, A.K., Cerretti, D.P., Wagner, G.C., Dreyer, J.-L. and Zhou, R. (1999) Specification of distinct dopaminergic neural pathways: roles of the Eph family receptor EphB1 and ligand ephrin-B2. J. Neurosci., 19, 2090-2101.
    • (1999) J. Neurosci. , vol.19 , pp. 2090-2101
    • Yue, Y.1    Widmer, D.A.J.2    Halladay, A.K.3    Cerretti, D.P.4    Wagner, G.C.5    Dreyer, J.-L.6    Zhou, R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.