The cytoplasmic domain of the ligand EphrinB2 is required for vascular morphogenesis but not cranial neural crest migration

Cell

Volumn 104, Issue 1, 2001, Pages 57-69

  Adams, Ralf H ^a   Diella, Francesca ^a   Hennig, Silvia ^b   Helmbacher, Françoise ^a   Deutsch, Urban ^b   Klein, Rüdiger ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; EPHRIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL MIGRATION; EMBRYO; EMBRYO DEVELOPMENT; LIGAND BINDING; MORPHOGENESIS; MOUSE; NEURAL CREST; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALIA; VERTEBRATA;

EID: 0035846911     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(01)00191-X     Document Type: Article

References (30)

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2. EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains
3. Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis
4. Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion
5. Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo
6. The ephrins and Eph receptors in neural development
7. Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development
8. Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrinB2 in cardiovascular development
9. The receptor tyrosine kinase EphB4 and ephrin-B ligands restrict angiogenic growth of embryonic veins in Xenopus laevis
10. Targeting of the EphA4 tyrosine kinase receptor affects dorsal/ventral pathfinding of limb motor axons
11. Nuk controls pathfinding of commissural axons in the mammalian central nervous sustem
12. Eph receptors and ephrins: Effectors of morphogenesis
13. BMP signaling is essential for development of skeletogenic and neurogenic cranial neural crest
14. Angiopoietin-1 induces sprouting angiogenesis in vitro
15. Rhombencephalic neural crest segmentation is preserved throughout craniofacial ontogeny
16. Interactions of Eph-related receptors and ligands confer rostrocaudal pattern to trunk neural crest migration
17. Kinase-dependent and kinase-independent functions of EphA4 receptors in major axon tract formation in vivo
18. Domains of cellular retinoic acid-binding protein I (CRABP I) expression in the hindbrain and neural crest of the mouse embryo
19. Eph receptors and ephrins restrict cell intermingling and communication
20. Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation
21. The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development
22. Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice
23. The zinc finger gene Krox20 regulates HoxB2 (Hox2.8) during hindbrain segmentation
24. The EphA4 and EphB1 receptor tyrosine kinases and ephrin-B2 ligand regulate targeted migration of branchial neural crest cells
25. Genetic interactions between Hoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning
26. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
27. Eph family transmembrane ligands can mediate repulsive guidance of trunk neural crest migration and motor axon outgrowth
28. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4
29. Eph receptors and ephrins: Regulators of guidance and assembly
30. In vivo cell sorting in complementary segmental domains mediated by Eph receptors and ephrins