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Volumn 9, Issue 7, 2003, Pages 2416-2425

Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3′-kinase/protein kinase B in prostate cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANDROGEN; ANDROGEN RECEPTOR; ANDROSTANOLONE; ANTIANDROGEN; ANTIBODY; BICALUTAMIDE; EPIDERMAL GROWTH FACTOR; FLUTAMIDE; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2; LIGAND; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN; PROTEIN KINASE B; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 0038004462     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (160)

References (67)
  • 1
    • 0033561382 scopus 로고    scopus 로고
    • Correlation between proliferation, apoptosis, and angiogenesis in prostate carcinoma and their relation to androgen ablation
    • Matsushima, H., Goto, T., Hosaka, Y., Kitamura, T., and Kawabe, K. Correlation between proliferation, apoptosis, and angiogenesis in prostate carcinoma and their relation to androgen ablation. Cancer (Phila.), 85: 1822-1827, 1999.
    • (1999) Cancer (Phila.) , vol.85 , pp. 1822-1827
    • Matsushima, H.1    Goto, T.2    Hosaka, Y.3    Kitamura, T.4    Kawabe, K.5
  • 2
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan, D., and Folkman, J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell, 86: 353-364, 1996.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 3
    • 0031969264 scopus 로고    scopus 로고
    • Angiogenesis and tumor metastasis
    • Zetter, B. R. Angiogenesis and tumor metastasis. Annu. Rev. Med., 49: 407-424, 1998.
    • (1998) Annu. Rev. Med. , vol.49 , pp. 407-424
    • Zetter, B.R.1
  • 4
    • 0029004025 scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
    • Dvorak, H. F., Brown, L. F., Detmar, M., and Dvorak, A. M. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am. J. Pathol., 146: 1029-1039, 1995.
    • (1995) Am. J. Pathol. , vol.146 , pp. 1029-1039
    • Dvorak, H.F.1    Brown, L.F.2    Detmar, M.3    Dvorak, A.M.4
  • 5
    • 0030939698 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) expression in human prostate cancer: In situ and in vitro expression of VEGF by human prostate cancer cells
    • Ferrer, F. A., Miller, L. J., Andrawis, R. I., Kurtzman, S. H., Albertsen, P. C., Laudone, V. P., and Kreutzer, D. L. Vascular endothelial growth factor (VEGF) expression in human prostate cancer: in situ and in vitro expression of VEGF by human prostate cancer cells. J. Urol., 157: 2329-2333, 1997.
    • (1997) J. Urol. , vol.157 , pp. 2329-2333
    • Ferrer, F.A.1    Miller, L.J.2    Andrawis, R.I.3    Kurtzman, S.H.4    Albertsen, P.C.5    Laudone, V.P.6    Kreutzer, D.L.7
  • 6
    • 0030993053 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) expression in prostate cancer and benign prostatic hyperplasia
    • Jackson, M. W., Bentel, J. M., and Tilley, W. D. Vascular endothelial growth factor (VEGF) expression in prostate cancer and benign prostatic hyperplasia. J. Urol., 157: 2323-2328, 1997.
    • (1997) J. Urol. , vol.157 , pp. 2323-2328
    • Jackson, M.W.1    Bentel, J.M.2    Tilley, W.D.3
  • 7
    • 0029805574 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor by insulin-like growth factor 1 in colorectal carcinoma
    • Warren, R. S., Yuan, H., Matli, M. R., Ferrara, N., and Donner, D. B. Induction of vascular endothelial growth factor by insulin-like growth factor 1 in colorectal carcinoma. J. Biol. Chem., 271: 29483-29488, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 29483-29488
    • Warren, R.S.1    Yuan, H.2    Matli, M.R.3    Ferrara, N.4    Donner, D.B.5
  • 8
    • 0030472169 scopus 로고    scopus 로고
    • Estrogen regulates vascular endothelial growth/permeability factor expression in 7, 12-dimethylbenz(a)anthracene-induced rat mammary tumors
    • Nakamura, J., Savinov, A., Lu, Q., and Brodie, A. Estrogen regulates vascular endothelial growth/permeability factor expression in 7, 12-dimethylbenz(a)anthracene-induced rat mammary tumors. Endocrinology, 137: 5589-5596, 1996.
    • (1996) Endocrinology , vol.137 , pp. 5589-5596
    • Nakamura, J.1    Savinov, A.2    Lu, Q.3    Brodie, A.4
  • 9
    • 0030035755 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is produced by peritoneal fluid macrophages in endometriosis and is regulated by ovarian steroids
    • McLaren, J., Prentice, A., Charnock-Jones, D. S., Millican, S. A., Muller, K. H., Sharkey, A. M., and Smith, S. K. Vascular endothelial growth factor is produced by peritoneal fluid macrophages in endometriosis and is regulated by ovarian steroids. J. Clin. Investig., 98: 482-489, 1996.
    • (1996) J. Clin. Investig. , vol.98 , pp. 482-489
    • McLaren, J.1    Prentice, A.2    Charnock-Jones, D.S.3    Millican, S.A.4    Muller, K.H.5    Sharkey, A.M.6    Smith, S.K.7
  • 10
    • 0028095127 scopus 로고
    • Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin
    • Goldberg, M. A., and Schneider, T. J. Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin. J. Biol. Chem., 269: 4355-4359, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 4355-4359
    • Goldberg, M.A.1    Schneider, T.J.2
  • 11
    • 0027960791 scopus 로고
    • Mammary fibroblasts may influence breast tumor angiogenesis via hypoxia-induced vascular endothelial growth factor up-regulation and protein expression
    • Hlatky, L., Tsionou, C., Hahnfeldt, P., and Coleman, C. N. Mammary fibroblasts may influence breast tumor angiogenesis via hypoxia-induced vascular endothelial growth factor up-regulation and protein expression. Cancer Res., 54: 6083-6086, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 6083-6086
    • Hlatky, L.1    Tsionou, C.2    Hahnfeldt, P.3    Coleman, C.N.4
  • 12
    • 0030046481 scopus 로고    scopus 로고
    • Interleukin 6 induces the expression of vascular endothelial growth factor
    • Cohen, T., Nahari, D., Cerem, L. W., Neufeld, G., and Levi, B. Z. Interleukin 6 induces the expression of vascular endothelial growth factor. J. Biol. Chem., 271: 736-741, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 736-741
    • Cohen, T.1    Nahari, D.2    Cerem, L.W.3    Neufeld, G.4    Levi, B.Z.5
  • 13
    • 0029794465 scopus 로고    scopus 로고
    • Uterine expression of vascular endothelial growth factor is increased by estradiol and tamoxifen
    • Hyder, S. M., Stancel, G. M., Chiappetta, C., Murthy, L., Boettger-Tong, H. L., and Makela, S. Uterine expression of vascular endothelial growth factor is increased by estradiol and tamoxifen. Cancer Res., 56: 3954-3960, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 3954-3960
    • Hyder, S.M.1    Stancel, G.M.2    Chiappetta, C.3    Murthy, L.4    Boettger-Tong, H.L.5    Makela, S.6
  • 14
    • 0029784688 scopus 로고    scopus 로고
    • Mechanism of dexamethasone suppression of brain tumor-associated vascular permeability in rats. Involvement of the glucocorticoid receptor and vascular permeability factor
    • Heiss, J. D., Papavassiliou, E., Merrill, M. J., Nieman, L., Knightly, J. J., Walbridge, S., Edwards, N. A., and Oldfield, E. H. Mechanism of dexamethasone suppression of brain tumor-associated vascular permeability in rats. Involvement of the glucocorticoid receptor and vascular permeability factor. J. Clin. Investig., 98: 1400-1408, 1996.
    • (1996) J. Clin. Investig. , vol.98 , pp. 1400-1408
    • Heiss, J.D.1    Papavassiliou, E.2    Merrill, M.J.3    Nieman, L.4    Knightly, J.J.5    Walbridge, S.6    Edwards, N.A.7    Oldfield, E.H.8
  • 15
    • 0028147863 scopus 로고
    • Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo
    • Minchenko, A., Bauer, T., Salceda, S., and Caro, J. Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo. Lab. Investig., 71: 374-379, 1994.
    • (1994) Lab. Investig. , vol.71 , pp. 374-379
    • Minchenko, A.1    Bauer, T.2    Salceda, S.3    Caro, J.4
  • 16
    • 0028105848 scopus 로고
    • Hypoxia regulatory elements of the human vascular endothelial growth factor gene
    • Minchenko, A., Salceda, S., Bauer, T., and Caro, J. Hypoxia regulatory elements of the human vascular endothelial growth factor gene. Cell Mol. Biol. Res., 40: 35-39, 1994.
    • (1994) Cell Mol. Biol. Res. , vol.40 , pp. 35-39
    • Minchenko, A.1    Salceda, S.2    Bauer, T.3    Caro, J.4
  • 17
    • 0027432324 scopus 로고
    • Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis
    • Plate, K. H., Breier, G., Millauer, B., Ullrich, A., and Risau, W. Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis. Cancer Res., 53: 5822-5827, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 5822-5827
    • Plate, K.H.1    Breier, G.2    Millauer, B.3    Ullrich, A.4    Risau, W.5
  • 18
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • Shweiki, D., Itin, A., Soffer, D., and Keshet, E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature (Lond.), 359: 843-845, 1992.
    • (1992) Nature (Lond.) , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 19
    • 0030869787 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element
    • Mazure, N. M., Chen, E. Y., Laderoute, K. R., and Giaccia, A. J. Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element. Blood, 90: 3322-3331, 1997.
    • (1997) Blood , vol.90 , pp. 3322-3331
    • Mazure, N.M.1    Chen, E.Y.2    Laderoute, K.R.3    Giaccia, A.J.4
  • 20
    • 0029761644 scopus 로고    scopus 로고
    • Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
    • Forsythe, J. A., Jiang, B. H., Iyer, N. V., Agani, F., Leung, S. W., Koos, R. D., and Semenza, G. L. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol. Cell. Biol., 16: 4604-4613, 1996.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4604-4613
    • Forsythe, J.A.1    Jiang, B.H.2    Iyer, N.V.3    Agani, F.4    Leung, S.W.5    Koos, R.D.6    Semenza, G.L.7
  • 21
    • 0029103274 scopus 로고
    • Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5′ enhancer
    • Liu, Y., Cox, S. R., Morita, T., and Kourembanas, S. Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5′ enhancer. Circ. Res., 77: 638-643, 1995.
    • (1995) Circ. Res. , vol.77 , pp. 638-643
    • Liu, Y.1    Cox, S.R.2    Morita, T.3    Kourembanas, S.4
  • 22
    • 0030588298 scopus 로고    scopus 로고
    • Absolute requirement of aryl hydrocarbon receptor nuclear translocator protein for gene activation by hypoxia
    • Salceda, S., Beck, I., and Caro, J. Absolute requirement of aryl hydrocarbon receptor nuclear translocator protein for gene activation by hypoxia. Arch. Biochem. Biophys., 334: 389-394, 1996.
    • (1996) Arch. Biochem. Biophys. , vol.334 , pp. 389-394
    • Salceda, S.1    Beck, I.2    Caro, J.3
  • 23
    • 0031417489 scopus 로고    scopus 로고
    • Androgens regulate vascular endothelial growth factor content in normal and malignant prostatic tissue
    • Joseph, I. B., Nelson, J. B., Denmeade, S. R., and Isaacs, J. T. Androgens regulate vascular endothelial growth factor content in normal and malignant prostatic tissue. Clin. Cancer Res., 3: 2507-2511, 1997.
    • (1997) Clin. Cancer Res. , vol.3 , pp. 2507-2511
    • Joseph, I.B.1    Nelson, J.B.2    Denmeade, S.R.3    Isaacs, J.T.4
  • 24
    • 0032500848 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is up-regulated in vitro and in vivo by androgens
    • Sordello, S., Bertrand, N., and Plouet, J. Vascular endothelial growth factor is up-regulated in vitro and in vivo by androgens. Biochem. Biophys. Res. Commun., 251: 287-290, 1998.
    • (1998) Biochem. Biophys. Res. Commun. , vol.251 , pp. 287-290
    • Sordello, S.1    Bertrand, N.2    Plouet, J.3
  • 25
    • 0035176826 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression and tumor angiogenesis are regulated by androgens in hormone responsive human prostate carcinoma: Evidence for androgen dependent destabilization of vascular endothelial growth factor transcripts
    • Stewart, R. J., Panigrahy, D., Flynn, E., and Folkman, J. Vascular endothelial growth factor expression and tumor angiogenesis are regulated by androgens in hormone responsive human prostate carcinoma: evidence for androgen dependent destabilization of vascular endothelial growth factor transcripts. J. Urol., 165: 688-693, 2001.
    • (2001) J. Urol. , vol.165 , pp. 688-693
    • Stewart, R.J.1    Panigrahy, D.2    Flynn, E.3    Folkman, J.4
  • 27
    • 0036216692 scopus 로고    scopus 로고
    • HIF-1 and tumor progression: Pathophysiology and therapeutics
    • Semenza, G. L. HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol. Med., 8: S62-67, 2002.
    • (2002) Trends Mol. Med. , vol.8
    • Semenza, G.L.1
  • 29
    • 0034654174 scopus 로고    scopus 로고
    • Modulation of hypoxia-inducible factor 1α expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
    • Zhong, H., Chiles, K., Feldser, D., Laughner, E., Hanrahan, C., Georgescu, M. M., Simons, J. W., and Semenza, G. L. Modulation of hypoxia-inducible factor 1α expression by the epidermal growth factor/ phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res., 60: 1541-1545, 2000.
    • (2000) Cancer Res. , vol.60 , pp. 1541-1545
    • Zhong, H.1    Chiles, K.2    Feldser, D.3    Laughner, E.4    Hanrahan, C.5    Georgescu, M.M.6    Simons, J.W.7    Semenza, G.L.8
  • 30
    • 0034925041 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1
    • Jiang, B. H., Jiang, G., Zheng, J. Z., Lu, Z., Hunter, T., and Vogt, P. K. Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1. Cell Growth Differ., 12: 363-369, 2001.
    • (2001) Cell Growth Differ. , vol.12 , pp. 363-369
    • Jiang, B.H.1    Jiang, G.2    Zheng, J.Z.3    Lu, Z.4    Hunter, T.5    Vogt, P.K.6
  • 31
    • 0035012605 scopus 로고    scopus 로고
    • HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1α (HIF-1α) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
    • Laughner, E., Taghavi, P., Chiles, K., Mahon, P. C., and Semenza, G. L. HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1α (HIF-1α) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol. Cell. Biol., 21: 3995-4004, 2001.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3995-4004
    • Laughner, E.1    Taghavi, P.2    Chiles, K.3    Mahon, P.C.4    Semenza, G.L.5
  • 32
    • 0035477438 scopus 로고    scopus 로고
    • Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1α. HIF-2α, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3′-kinase/Akt signaling pathway
    • Blancher, C., Moore, J. W., Robertson, N., and Harris, A. L. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1α. HIF-2α, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3′-kinase/Akt signaling pathway. Cancer Res., 61: 7349-7355, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 7349-7355
    • Blancher, C.1    Moore, J.W.2    Robertson, N.3    Harris, A.L.4
  • 33
    • 0037070223 scopus 로고    scopus 로고
    • Normoxic induction of the hypoxia-inducible factor 1α by insulin and interleukin-1β involves the phosphatidylinositol 3-kinase pathway
    • Stiehl, D. P., Jelkmann, W., Wenger, R. H., and Hellwig-Burgel, T. Normoxic induction of the hypoxia-inducible factor 1α by insulin and interleukin-1β involves the phosphatidylinositol 3-kinase pathway. FEBS Lett., 512: 157-162, 2002.
    • (2002) FEBS Lett. , vol.512 , pp. 157-162
    • Stiehl, D.P.1    Jelkmann, W.2    Wenger, R.H.3    Hellwig-Burgel, T.4
  • 34
    • 0037177867 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1α nor sufficient for HIF-1-dependent target gene transcription
    • Arsham, A. M., Plas, D. R., Thompson, C. B., and Simon, M. C. Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1α nor sufficient for HIF-1-dependent target gene transcription. J. Biol. Chem., 277: 15162-15170, 2002.
    • (2002) J. Biol. Chem. , vol.277 , pp. 15162-15170
    • Arsham, A.M.1    Plas, D.R.2    Thompson, C.B.3    Simon, M.C.4
  • 36
    • 0033870281 scopus 로고    scopus 로고
    • The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages
    • Talks, K. L., Turley, H., Gatter, K. C., Maxwell, P. H., Pugh, C. W., Ratcliffe, P. J., and Harris, A. L. The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages. Am. J. Pathol., 157: 411-421, 2000.
    • (2000) Am. J. Pathol. , vol.157 , pp. 411-421
    • Talks, K.L.1    Turley, H.2    Gatter, K.C.3    Maxwell, P.H.4    Pugh, C.W.5    Ratcliffe, P.J.6    Harris, A.L.7
  • 37
    • 0034667433 scopus 로고    scopus 로고
    • Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer
    • Salnikow, K., Costa, M., Figg, W. D., and Blagosklonny, M. V. Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer. Cancer Res., 60: 5630-5634, 2000.
    • (2000) Cancer Res. , vol.60 , pp. 5630-5634
    • Salnikow, K.1    Costa, M.2    Figg, W.D.3    Blagosklonny, M.V.4
  • 40
    • 0034896068 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor 1α in epithelial ovarian tumors: Its impact on prognosis and on response to chemotherapy
    • Birner, P., Schindl, M., Obermair, A., Breitenecker, G., and Oberhuber, G. Expression of hypoxia-inducible factor 1α in epithelial ovarian tumors: its impact on prognosis and on response to chemotherapy. Clin. Cancer Res., 7: 1661-1668, 2001.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1661-1668
    • Birner, P.1    Schindl, M.2    Obermair, A.3    Breitenecker, G.4    Oberhuber, G.5
  • 41
    • 0034282518 scopus 로고    scopus 로고
    • Overexpression of hypoxia-inducible factor la is a marker for an unfavorable prognosis in early-stage invasive cervical cancer
    • Birner, P., Schindl, M., Obermair, A., Plank, C., Breitenecker, G., and Oberhuber, G. Overexpression of hypoxia-inducible factor la is a marker for an unfavorable prognosis in early-stage invasive cervical cancer. Cancer Res., 60: 4693-4696, 2000.
    • (2000) Cancer Res. , vol.60 , pp. 4693-4696
    • Birner, P.1    Schindl, M.2    Obermair, A.3    Plank, C.4    Breitenecker, G.5    Oberhuber, G.6
  • 42
    • 0035266307 scopus 로고    scopus 로고
    • Hypoxia inducible factor (HIF-1a and HIF-2a) expression in early esophageal cancer and response to photodynamic therapy and radiotherapy
    • Koukourakis, M. I., Giatromanolaki, A., Skarlatos, J., Corti, L., Blandamura, S., Piazza, M., Gatter, K. C., and Harris, A. L. Hypoxia inducible factor (HIF-1a and HIF-2a) expression in early esophageal cancer and response to photodynamic therapy and radiotherapy. Cancer Res., 61: 1830-1832, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 1830-1832
    • Koukourakis, M.I.1    Giatromanolaki, A.2    Skarlatos, J.3    Corti, L.4    Blandamura, S.5    Piazza, M.6    Gatter, K.C.7    Harris, A.L.8
  • 43
    • 0035503362 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer
    • Giatromanolaki, A., Koukourakis, M. I., Sivridis, E., Pastorek, J., Wykoff, C. C., Gatter, K. C., and Harris, A. L. Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer. Cancer Res., 61: 7992-7998, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 7992-7998
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Sivridis, E.3    Pastorek, J.4    Wykoff, C.C.5    Gatter, K.C.6    Harris, A.L.7
  • 44
    • 0035860147 scopus 로고    scopus 로고
    • Relation of hypoxia inducible factor 1 α and 2 α in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival
    • Giatromanolaki, A., Koukourakis, M. I., Sivridis, E., Turley, H., Talks, K., Pezzella, F., Gatter, K. C., and Harris, A. L. Relation of hypoxia inducible factor 1 α and 2 α in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival. Br. J. Cancer, 85: 881-890, 2001.
    • (2001) Br. J. Cancer , vol.85 , pp. 881-890
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Sivridis, E.3    Turley, H.4    Talks, K.5    Pezzella, F.6    Gatter, K.C.7    Harris, A.L.8
  • 45
    • 0035300410 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1α: A novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer
    • Aebersold, D. M., Burri, P., Beer, K. T., Laissue, J., Djonov, V., Greiner, R. H., and Semenza, G. L. Expression of hypoxia-inducible factor-1α: a novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer. Cancer Res., 61: 2911-2916, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 2911-2916
    • Aebersold, D.M.1    Burri, P.2    Beer, K.T.3    Laissue, J.4    Djonov, V.5    Greiner, R.H.6    Semenza, G.L.7
  • 47
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia-a key regulatory factor in tumour growth
    • Harris, A. L. Hypoxia-a key regulatory factor in tumour growth. Nat. Rev. Cancer, 2: 38-47, 2002.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 48
    • 0029859510 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension
    • Jiang, B. H., Semenza, G. L., Bauer, C., and Marti, H. H. Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension. Am. J. Physiol., 271: C1172-1180, 1996.
    • (1996) Am. J. Physiol. , vol.271
    • Jiang, B.H.1    Semenza, G.L.2    Bauer, C.3    Marti, H.H.4
  • 49
    • 0035698574 scopus 로고    scopus 로고
    • Generation of bidirectional hypoxia/HIF-responsive expression vectors to target gene expression to hypoxi cells
    • Post, D. E., and Van Meir, E. G. Generation of bidirectional hypoxia/HIF-responsive expression vectors to target gene expression to hypoxic cells. Gene Ther., 8: 1801-1807, 2001.
    • (2001) Gene Ther. , vol.8 , pp. 1801-1807
    • Post, D.E.1    Van Meir, E.G.2
  • 50
    • 0036569704 scopus 로고    scopus 로고
    • Geldanamycin induces degradation of hypoxia-inducible factor 1α protein via the proteosome pathway in prostate cancer cells
    • Mabjeesh, N. J., Post, D. E., Willard, M. T., Kaur, B., Van Meir, E. G., Simons, J. W., and Zhong, H. Geldanamycin induces degradation of hypoxia-inducible factor 1α protein via the proteosome pathway in prostate cancer cells. Cancer Res., 62: 2478-2482, 2002.
    • (2002) Cancer Res. , vol.62 , pp. 2478-2482
    • Mabjeesh, N.J.1    Post, D.E.2    Willard, M.T.3    Kaur, B.4    Van Meir, E.G.5    Simons, J.W.6    Zhong, H.7
  • 52
    • 0037133736 scopus 로고    scopus 로고
    • Identification of an additional hypoxia responsive element in the glyceraldehyde-3-phosphate dehydrogenase gene promoter
    • Lu, S., Gu, X., Hoestje, S., and Epner, D. E. Identification of an additional hypoxia responsive element in the glyceraldehyde-3-phosphate dehydrogenase gene promoter. Biochim. Biophys. Acta, 1574: 152-156, 2002.
    • (2002) Biochim. Biophys. Acta , vol.1574 , pp. 152-156
    • Lu, S.1    Gu, X.2    Hoestje, S.3    Epner, D.E.4
  • 53
    • 0032741858 scopus 로고    scopus 로고
    • Identification of an oxygen responsive enhancer element in the glyceraldehyde-3-phosphate dehydrogenase gene
    • Graven, K. K., Yu, Q., Pan, D., Roncarati, J. S., and Farber, H. W. Identification of an oxygen responsive enhancer element in the glyceraldehyde-3-phosphate dehydrogenase gene. Biochim. Biophys. Acta, 1447: 208-218, 1999.
    • (1999) Biochim. Biophys. Acta , vol.1447 , pp. 208-218
    • Graven, K.K.1    Yu, Q.2    Pan, D.3    Roncarati, J.S.4    Farber, H.W.5
  • 54
    • 0033575003 scopus 로고    scopus 로고
    • Direct comparison of GAPDH, β-actin, cyclophilin, and 28S rRNA as internal standards for quantifying RNA levels under hypoxia
    • Zhong, H., and Simons, J. W. Direct comparison of GAPDH, β-actin, cyclophilin, and 28S rRNA as internal standards for quantifying RNA levels under hypoxia. Biochem. Biophys. Res. Commun., 259: 523-526, 1999.
    • (1999) Biochem. Biophys. Res. Commun. , vol.259 , pp. 523-526
    • Zhong, H.1    Simons, J.W.2
  • 55
    • 0028068606 scopus 로고
    • Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
    • Semenza, G. L., Roth, P. H., Fang, H. M., and Wang, G. L. Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J. Biol. Chem., 269: 23757-23763, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 23757-23763
    • Semenza, G.L.1    Roth, P.H.2    Fang, H.M.3    Wang, G.L.4
  • 56
    • 0028998283 scopus 로고
    • Androgenic and antiandrogenic control on epidermal growth factor, epidermal growth factor receptor, and androgen receptor expression in human prostate cancer cell line LNCaP
    • Ravenna, L., Lubrano, C., Di Silverio, F., Vacca, A., Felli, M. P., Maroder, M., D'Eramo, G., Sciarra, F., Frati, L., Gulino, A., and et al. Androgenic and antiandrogenic control on epidermal growth factor, epidermal growth factor receptor, and androgen receptor expression in human prostate cancer cell line LNCaP. Prostate, 26: 290-298, 1995.
    • (1995) Prostate , vol.26 , pp. 290-298
    • Ravenna, L.1    Lubrano, C.2    Di Silverio, F.3    Vacca, A.4    Felli, M.P.5    Maroder, M.6    D'Eramo, G.7    Sciarra, F.8    Frati, L.9    Gulino, A.10
  • 57
    • 0029040399 scopus 로고
    • Androgen up-regulates epidermal growth factor receptor expression and binding affinity in PC3 cell lines expressing the human androgen receptor
    • Brass, A. L., Barnard, J., Patai, B. L., Salvi, D., and Rukstalis, D. B. Androgen up-regulates epidermal growth factor receptor expression and binding affinity in PC3 cell lines expressing the human androgen receptor. Cancer Res., 55: 3197-3203, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 3197-3203
    • Brass, A.L.1    Barnard, J.2    Patai, B.L.3    Salvi, D.4    Rukstalis, D.B.5
  • 60
    • 0026702395 scopus 로고
    • Hormonal regulation of prostate-specific antigen (PSA) glycoprotein in the human prostatic adenocarcinoma cell line LNCaP
    • Montgomery, B. T., Young, C. Y., Bilhartz, D. L., Andrews, P. E., Prescott, J. L., Thompson, N. F., and Tindall, D. J. Hormonal regulation of prostate-specific antigen (PSA) glycoprotein in the human prostatic adenocarcinoma cell line. LNCaP. Prostate, 21: 63-73, 1992.
    • (1992) Prostate , vol.21 , pp. 63-73
    • Montgomery, B.T.1    Young, C.Y.2    Bilhartz, D.L.3    Andrews, P.E.4    Prescott, J.L.5    Thompson, N.F.6    Tindall, D.J.7
  • 61
    • 0035045386 scopus 로고    scopus 로고
    • Epidermal growth factor modulates the expression of vascular endothelial growth factor in the human prostate
    • Ravindranath, N., Wion, D., Brachet, P., and Djakiew, D. Epidermal growth factor modulates the expression of vascular endothelial growth factor in the human prostate. J. Androl., 22: 432-443, 2001.
    • (2001) J. Androl. , vol.22 , pp. 432-443
    • Ravindranath, N.1    Wion, D.2    Brachet, P.3    Djakiew, D.4
  • 62
    • 0034566055 scopus 로고    scopus 로고
    • Expression and function of androgen receptor in carcinoma of the prostate
    • Culig, Z., Hobisch, A., Bartsch, G., and Klocker, H. Expression and function of androgen receptor in carcinoma of the prostate. Microsc. Res. Tech., 51: 447-455, 2000.
    • (2000) Microsc. Res. Tech. , vol.51 , pp. 447-455
    • Culig, Z.1    Hobisch, A.2    Bartsch, G.3    Klocker, H.4
  • 63
    • 0033838227 scopus 로고    scopus 로고
    • Androgen receptor-an update of mechanisms of action in prostate cancer
    • Culig, Z., Hobisch, A., Bartsch, G., and Klocker, H. Androgen receptor-an update of mechanisms of action in prostate cancer. Urol. Res., 28: 211-219, 2000.
    • (2000) Urol. Res. , vol.28 , pp. 211-219
    • Culig, Z.1    Hobisch, A.2    Bartsch, G.3    Klocker, H.4
  • 64
    • 0036122242 scopus 로고    scopus 로고
    • Involvement of hypoxia-inducible factor 1 in human cancer
    • Semenza, G. L. Involvement of hypoxia-inducible factor 1 in human cancer. Intern. Med., 41: 79-83, 2002.
    • (2002) Intern. Med. , vol.41 , pp. 79-83
    • Semenza, G.L.1
  • 65
    • 0037106273 scopus 로고    scopus 로고
    • Targeting the epidermal growth factor receptor for cancer therapy
    • Mendelsohn, J. Targeting the epidermal growth factor receptor for cancer therapy. J. Clin. Oncol., 20: 1S-13S, 2002.
    • (2002) J. Clin. Oncol. , vol.20
    • Mendelsohn, J.1
  • 66
    • 0036096775 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by the antiepidermal growth factor receptor antibody ImClone C225 in androgen-independent prostate cancer growing orthotopically in nude mice
    • Karashima, T., Sweeney, P., Slaton, J. W., Kim, S. J., Kedar, D., Izawa, J. I., Fan, Z., Pettaway, C., Hicklin, D. J., Shuin, T., and Dinney, C. P. Inhibition of angiogenesis by the antiepidermal growth factor receptor antibody ImClone C225 in androgen-independent prostate cancer growing orthotopically in nude mice. Clin. Cancer Res., 8: 1253-1264, 2002.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 1253-1264
    • Karashima, T.1    Sweeney, P.2    Slaton, J.W.3    Kim, S.J.4    Kedar, D.5    Izawa, J.I.6    Fan, Z.7    Pettaway, C.8    Hicklin, D.J.9    Shuin, T.10    Dinney, C.P.11
  • 67
    • 0034896362 scopus 로고    scopus 로고
    • Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor
    • Ciardiello, F., Caputo, R, Bianco, R., Damiano, V., Fontanini, G., Cuccato, S., De Placido, S., Bianco, A. R., and Tortora, G. Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor. Clin. Cancer Res., 7: 1459-1465, 2001.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1459-1465
    • Ciardiello, F.1    Caputo, R.2    Bianco, R.3    Damiano, V.4    Fontanini, G.5    Cuccato, S.6    De Placido, S.7    Bianco, A.R.8    Tortora, G.9


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