Altered amyloid-β metabolism and deposition in genomic-based β-secretaee transgenic mice

Journal of Biological Chemistry

Volumn 279, Issue 50, 2004, Pages 52535-52542

  Chiocco, Matthew J ^a   Kulnane, Laura Shapiro ^a   Younkin, Linda ^b   Younkin, Steve ^b   Evin, Geneviève ^c   Lamb, Bruce T ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MAYO CLINIC   (United States)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BRAIN; DISEASES; ENZYMES; PROTEINS; RNA;

ALZHEIMER'S DISEASES (AD); AMYLOID DEPOSITION; AMYLOID PRECURSOR PROTEIN (APP); RATE-LIMITING CLEAVAGES;

GENES;

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BETA SECRETASE 1; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN METABOLISM; CONTROLLED STUDY; GENE OVEREXPRESSION; GENOME ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METABOLISM; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; ENDOPEPTIDASES; FEMALE; GENE EXPRESSION; GENOMICS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, MESSENGER;

ANIMALIA; MUS MUSCULUS;

EID: 10844278034     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M409680200     Document Type: Article

References (55)

1. Tanzi, R. E. (1999) J. Clin. Investig. 104, 1175-1179
2. Glenner, G. G., and Wong, C. W. (1984) Biochem. Biophys. Res. Commun. 120, 885-890
3. Braak, H., and Braak, E. (1997) Neurobiol. Aging 18, 351-357
4. Vassar, R., Bennett, B. D., Babu-Khan, S., Kahn, S., Mendiaz, E. A., Denis, P., Teplow, D. B., Ross, S., Amarante, P., Loeloff, R., Luo, Y., Fisher, S., Fuller, J., Edenson, S., Lile, J., Jarosinski, M. A., Biere, A. L., Curran, E., Burgess, T., Louis, J. C., Collins, F., Treanor, J., Rogers, G., and Citron, M. (1999) Science 288, 735-741
5. Cai, H., Wang, Y., McCarthy, D., Wen, H., Borchelt, D. R., Price, D. L., and Wong, P. C. (2001) Nat. Neurosci. 4, 233-234
6. Selkoe, D. J. (1999) Nature 399, A23-31
7. Mullan, M., Crawford, F., Axelman, K., Houlden, H., Lilius, L., Winblad, B., and Lannfelt, L. (1992) Nat. Genet. 1, 345-347
8. Citron, M., Oltersdorf, T., Haass, C., McConlogue, L., Hung, A. Y., Seubert, P., Vigo-Pelfrey, C., Lieberburg, I., and Selkoe, D. J. (1992) Nature 360, 672-674
9. Lamb, B. T., Call, L. M., Slunt, H. H., Bardel, K. A., Lawler, A. M., Eckman, C. B., Younkin, S. G., Holtz, G., Wagner, S. L., Price, D. L., Sisodia, S. S., and Gearhart, J. D. (1997) Hum. Mol. Genet. 6, 1535-1541
10. Yan, R., Bienkowski, M. J., Shuck, M. E., Miao, H., Tory, M. C., Pauley, A. M., Brashler, J. R., Stratman, N. C., Mathews, W. R., Buhl, A. E., Carter, D. B., Tomasselli, A. G., Parodi, L. A., Heinrikson, R. L., and Gurney, M. E. (1999) Nature 402, 533-537
11. Sinha, S., Anderson, J. P., Barbour, R., Basi, G. S., Caccavelio, R., Davis, D., Doan, M., Dovey, H. F., Frigon, N., Hong, J., Jacobson-Croak, K., Jewett, N., Keim, P., Knops, J., Lieberburg, I., Power, M., Tan, H., Tatsuno, G., Tung, J., Schenk, D., Seubert, P., Suomensaari, S. M., Wang, S., Walker, D., Zhao, J., McConlogue, L., and John, V. (1999) Nature 402, 537-540
12. Hussain, I., Powell, D., Howlett, D. R., Tew, D. G., Meek, T. D., Chapman, C., Gloger, I. S., Murphy, K. E., Southan, C. D., Ryan, D. M., Smith, T. S., Simmons, D. L., Walsh, F. S., Dingwall, C., and Christie, G. (1999) Mol. Cell Neurosci. 14, 419-427
13. Fukumoto, H., Cheung, B. S., Hyman, B. T., and Irizarry, M. C. (2002) Arch. Neurol. 59, 1381-1389
14. Sun, A., Koelsch, G., Tang, J., and Bing, G. (2002) Exp. Neurol. 175, 10-22
15. Yang, L. B., Lindholm, K., Yan, R., Citron, M., Xia, W., Yang, X. L., Beach, T., Sue, L., Wong, P., Price, D., Li, R., and Shen, Y. (2003) Nat. Med. 9, 3-4
16. Roberds, S. L., Anderson, J., Basi, G., Bienkowski, M. J., Branstetter, D. G., Chen, K. S., Freedman, S. B., Frigon, N. L., Games, D., Hu, K., Johnson-Wood, K., Kappenman, K. E., Kawabe, T. T., Kola, I., Kuehn, R., Lee, M., Liu, W., Motter, R., Nichols, N. F., Power, M., Robertson, D. W., Schenk, D., Schoor, M., Shopp, G. M., Shuck, M. E., Sinha, S., Svensson, K. A., Tatsuno, G., Tintrup, H., Wijsman, J., Wright, S., and McConlogue, L. (2001) Hum. Mol. Genet. 10, 1317-1324
17. Luo, Y., Bolon, B., Kahn, S., Bennett, B. D., Babu-Khan, S., Denis, P., Fan, W., Kha, H., Zhang, J., Gong, Y., Martin, L., Louis, J. C., Yan, Q., Richards, W. G., Citron, M., and Vassar, R. (2001) Nat. Neurosci. 4, 231-232
18. Yang, X. W., Model, P., and Heintz, N. (1997) Nat. Biotechnol. 15, 859-865
19. Hogan, B., Beddington, R., Constantini, F., and Lacy, E. (1994) Manipulating the Mouse Embryo, 2nd Ed., pp. 217-251, Cold Spring Harbor Laboratory Press, Cold Spring Harbor
20. Miller, S. A., Dykes, D. D., and Polesky, H. F. (1988) Nucleic Acids Res. 16, 1215
21. Sambrook, J. a. R., David W. (2001) in Molecular Cloning: A Laboratory Manual, Third Edition Ed. (Argentine, J., ed.) Vol. 1, pp. 23-64, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
22. Lamb, B. T., Sisodia, S. S., Lawler, A. M., Slunt, H. H., Kitt, C. A., Kearns, W. G., Pearson, P. L., Price, D. L., and Gearhart, J. D. (1993) Nat. Genet. 5, 22-30
23. Holsinger, R. M., McLean, C. A., Beyreuther, K., Masters, C. L., and Evin, G. (2002) Ann. Neurol. 51, 783-786
24. DeMattos, R. B., O'Dell M, A., Parsadanian, M., Taylor, J. W., Harmony, J. A., Bales, K. R., Paul, S. M., Aronow, B. J., and Holtzman, D. M. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 10843-10848
25. Johnson-Wood, K., Lee, M., Motter, R., Hu, K., Gordon, G., Barbour, R., Khan, K., Gordon, M., Tan, H., Games, D., Lieberburg, I., Schenk, D., Seubert, P., and McConlogue, L. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 1550-1555
26. Suzuki, N., Cheung, T. T., Cai, X. D., Odaka, A., Otvos, L., Jr., Eckman, C., Golde, T. E., and Younkin, S. G. (1994) Science 264, 1336-1340
27. Kulnane, L. S., and Lamb, B. T. (2001) Neurobiol. Dis. 8, 982-992
28. Van, R., Han, P., Miao, H., Greengard, P., and Xu, H. (2001) J. Biol. Chem. 276, 36788-36796
29. Parinos, G. F., and Keith, B. J. (2001) The Mouse Brain in Stereotaxic Coordinates, 2nd Ed., pp. 108-121, Academic Press, San Diego
30. Saunders, A. J., Kim, T.-W., and Tanzi, R. E. (1999) Science 286, 1255a
31. Kinoshita, A., Fukumoto, H., Shah, T., Whelan, C. M., Irizarry, M. C., and Hyman, B. T. (2003) J. Cell Sci. 116, 3339-3346
32. Hsiao, K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., S., Y., Yang, F., and Cole, G. (1996) Science 274, 99-102
33. Liu, H. C., Leu, S. J., Chang, J. G., Sung, S. M., Hsu, W. C., Lee, L. S., and Hu, C. J. (2003) Brain Res. 961, 88-91
34. Nicolaou, M., Song, Y. Q., Sato, C. A., Orlacchio, A., Kawarai, T., Medeiros, H., Liang, Y., Sorbi, S., Richard, E., Rogaev, E. I., Moliaka, Y., Bruni, A. C., Jorge, R., Percy, M., Duara, R., Farrer, L. A., St Georg-Hyslop, P., and Rogaeva, E. A. (2001) Neurogenetics 3, 203-206
35. Nowotny, P., Kwon, J. M., Chakraverty, S., Nowotny, V., Morris, J. C., and Goate, A. M. (2001) Neuroreport 12, 1799-1802
36. Gold, G., Blouin, J. L., Herrmann, F. R., Michon, A., Mulligan, R., Duriaux Sail, G., Bouras, C., Giannakopoulos, P., and Antonarakis, S. E. (2003) Am. J. Med. Genet. 119B, 44-47
37. Clarimon, J., Bertranpetit, J., Calafell, F., Boada, M., Tarraga, L., and Comas, D. (2003) J. Neurol. 250, 956-961
38. Bodendorf, U., Danner, S., Fischer, F., Stefani, M., Sturchler-Pierrat, C., Wiederhold, K. H., Staufenbiel, M., and Paganetti, P. (2002) J. Neurochem. 80, 799-806
39. Mohajeri, M. H., Saini, K. D., and Nitsch, R. M. (2004) J. Neural. Transm. 111, 413-425
40. Marcinkiewicz, M., and Seidah, N. G. (2000) J. Neurochem. 75, 2133-2143
41. Irizarry, M. C., Locascio, J. J., and Hyman, B. T. (2001) Am. J. Pathol. 158, 173-177
42. Kawarabayashi, T., Younkin, L. H., Saido, T. C., Shoji, M., Ashe, K. H., and Younkin, S. G. (2001) J. Neurosci. 21, 372-381
43. Lehman, E. J., Kulnane, L. S., and Lamb, B. T. (2003) Neurobiol. Aging 24, 645-653
44. Zohar, O., Cavallaro, S., D'Agata, V., and Alkon, D. L. (2003) Brain Res. Mol. Brain Res. 115, 63-68
45. Li, R., Lindholm, K., Yang, L. B., Yue, X., Citron, M., Yan, R., Beach, T., Sue, L., Sabbagh, M., Cai, H., Wong, P., Price, D., and Shen, Y. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 3632-3637
46. Doty, R. L., Reyes, P. F., and Gregor, T. (1987) Brain Res. Bull. 18, 597-600
47. Serby, M., Larson, P., and Kalkstein, D. (1991) Am. J. Psychiatry. 148, 357-360
48. Serby, M., Mohan, C., Aryan, M., Williams, L., Mohs, R. C., and Davis, K. L. (1996) Biol. Psych. 39, 375-377
49. Christen-Zaech, S., Kraftsik, R., Pillevuit, O., Kiraly, M., Martins, R., Khalili, K, and Miklossy, J. (2003) Can. J. Neurol. Sci. 30, 20-25
50. Kovacs, T., Cairns, N. J., and Lantoa, P. L. (2001) Neuroreport 12, 285-288
51. Kandel, E. R., Schwartz, J. H., and Jessel, T. M. (eds) (2000) Principles of Neural Science, 4th Ed., pp. 625-647, McGraw-Hill, New York
52. Kovacs, T. (2004) Ageing Res. Rev. 3, 215-232
53. Sheng, J. G., Price, D. L., and Koliatsos, V. E. (2003) Exp. Neurol. 184, 1053-1057
54. Kamal, A., Almenar-Queralt, A., LeBlanc, J. F., Roberts, E. A., and Goldstein, L. S. (2001) Nature 414, 643-648
55. Delatour, B., Blanchard, V., Pradier, L., and Duyckaerts, C. (2004) Neurobiol. Dis. 16, 41-47