-
1
-
-
0034611791
-
Obesity as a medical problem
-
Kopelman PG. Obesity as a medical problem. Nature 2000; 404:635-43.
-
(2000)
Nature
, vol.404
, pp. 635-643
-
-
Kopelman, P.G.1
-
2
-
-
0033533859
-
Body-mass index and mortality in a prospective cohort of U.S. adults
-
Calle EE, Thun MJ, Petrelli JM, Rodriguez C, Heath CW, Jr. Body-mass index and mortality in a prospective cohort of U.S. adults. N Engl J Med 1999; 341:1097-105.
-
(1999)
N Engl J Med
, vol.341
, pp. 1097-1105
-
-
Calle, E.E.1
Thun, M.J.2
Petrelli, J.M.3
Rodriguez, C.4
Heath Jr., C.W.5
-
3
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca P, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372:425-32.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, P.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
4
-
-
0033517284
-
Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy
-
Shimomura I, Hammer RE, Ikemoto S, Brown MS, Goldstein JL. Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy. Nature 1999; 401:73-6.
-
(1999)
Nature
, vol.401
, pp. 73-76
-
-
Shimomura, I.1
Hammer, R.E.2
Ikemoto, S.3
Brown, M.S.4
Goldstein, J.L.5
-
5
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartaglia LA, Dembski M, Weng X, et al. Identification and expression cloning of a leptin receptor, OB-R. Cell 1995; 83:1263-71.
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
-
6
-
-
0030039272
-
Abnormal splicing of the leptin receptor in diabetic mice
-
Lee GH, Proenca R, Montez JM, et al. Abnormal splicing of the leptin receptor in diabetic mice. Nature 1996; 379:632-5.
-
(1996)
Nature
, vol.379
, pp. 632-635
-
-
Lee, G.H.1
Proenca, R.2
Montez, J.M.3
-
7
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen H, Charlat O, Tartaglia LA, et al. Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice. Cell 1996; 84:491-5.
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
-
8
-
-
0029895233
-
Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization
-
Mercer JG, Hoggard N, Williams LM, Lawrence CB, Hannah LT, Trayhurn P. Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization. FEBS Letters 1996; 387:113-6.
-
(1996)
FEBS Letters
, vol.387
, pp. 113-116
-
-
Mercer, J.G.1
Hoggard, N.2
Williams, L.M.3
Lawrence, C.B.4
Hannah, L.T.5
Trayhurn, P.6
-
9
-
-
0030015417
-
Defective STAT signaling by the leptin receptor in diabetic mice
-
Ghilardi N, Ziegler S, Wiestner A, Stoffel R, Heim MH, Skoda R. Defective STAT signaling by the leptin receptor in diabetic mice. Proc Natl Acad Sci USA 1996; 93:6231-5.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6231-6235
-
-
Ghilardi, N.1
Ziegler, S.2
Wiestner, A.3
Stoffel, R.4
Heim, M.H.5
Skoda, R.6
-
10
-
-
0030737953
-
Physiological response to long-term peripheral and central leptin infusion in lean and obese mice
-
Halaas JL, Boozer C, Blair-West J, Fidahusein N, Denton D, Friedman JM. Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. Proc Natl Acad Sci USA 1997; 94:8878-83.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8878-8883
-
-
Halaas, J.L.1
Boozer, C.2
Blair-West, J.3
Fidahusein, N.4
Denton, D.5
Friedman, J.M.6
-
11
-
-
0032860996
-
Rapid increase in circulating leptin in ventromedial hypothalamus-lesioned rats: Role of hyperinsulinemia and implication for upregulation mechanism
-
Suga A, Hirano T, Kageyama H, et al. Rapid increase in circulating leptin in ventromedial hypothalamus-lesioned rats: role of hyperinsulinemia and implication for upregulation mechanism. Diabetes 1999; 48:2034-8.
-
(1999)
Diabetes
, vol.48
, pp. 2034-2038
-
-
Suga, A.1
Hirano, T.2
Kageyama, H.3
-
12
-
-
0031440266
-
Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels
-
Spanswick D, Smith MA, Groppi VE, Logan SD, Ashford ML. Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels. Nature 1997; 390:521-5.
-
(1997)
Nature
, vol.390
, pp. 521-525
-
-
Spanswick, D.1
Smith, M.A.2
Groppi, V.E.3
Logan, S.D.4
Ashford, M.L.5
-
13
-
-
0034611732
-
Central nervous system control of food intake
-
Schwartz MW, Woods SC, Porte D Jr, Seeley RJ, Baskin DG. Central nervous system control of food intake. Nature 2000; 404:661-71.
-
(2000)
Nature
, vol.404
, pp. 661-671
-
-
Schwartz, M.W.1
Woods, S.C.2
Porte Jr., D.3
Seeley, R.J.4
Baskin, D.G.5
-
14
-
-
0034611675
-
Obesity in the new millennium
-
Friedman JM. Obesity in the new millennium. Nature 2000; 404:632-4.
-
(2000)
Nature
, vol.404
, pp. 632-634
-
-
Friedman, J.M.1
-
15
-
-
0030840464
-
STATs and gene regulation
-
Darnell JE. STATs and gene regulation. Science 1997; 277:1630-5.
-
(1997)
Science
, vol.277
, pp. 1630-1635
-
-
Darnell, J.E.1
-
16
-
-
0029739826
-
Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice
-
Vaisse C, Halaas JL, Horvath CM, Darnell JE Jr, Stoffel M, Friedman JM. Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nature Genetics 1996; 14:95-7.
-
(1996)
Nature Genetics
, vol.14
, pp. 95-97
-
-
Vaisse, C.1
Halaas, J.L.2
Horvath, C.M.3
Darnell Jr., J.E.4
Stoffel, M.5
Friedman, J.M.6
-
17
-
-
10544236913
-
Functional STAT 1 and 3 signaling by the leptin receptor (OB-R); reduced expression of the rat fatty leptin receptor in transfected cells
-
Rosenblum CI, Tota M, Cully D, et al. Functional STAT 1 and 3 signaling by the leptin receptor (OB-R); reduced expression of the rat fatty leptin receptor in transfected cells. Endocrinology 1996; 137:5178-81.
-
(1996)
Endocrinology
, vol.137
, pp. 5178-5181
-
-
Rosenblum, C.I.1
Tota, M.2
Cully, D.3
-
18
-
-
0029776030
-
The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors
-
Baumann H, Morella KK, White DW, et al. The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors. Proc Natl Acad Sci USA 1996; 93:8374-8.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8374-8378
-
-
Baumann, H.1
Morella, K.K.2
White, D.W.3
-
19
-
-
0030956390
-
The leptin receptor activates Janus kinase 2 and signals for proliferation in a factor-dependent cell line
-
Ghilardi N, Skoda RC. The leptin receptor activates Janus kinase 2 and signals for proliferation In a factor-dependent cell line. Mol Endocrinology 1997; 11:393-99.
-
(1997)
Mol Endocrinology
, vol.11
, pp. 393-399
-
-
Ghilardi, N.1
Skoda, R.C.2
-
20
-
-
0027327484
-
JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin
-
Witthuhn BA, Quelle FW, Silvennoinen O, et al. JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin. Cell 1993; 74:227-36.
-
(1993)
Cell
, vol.74
, pp. 227-236
-
-
Witthuhn, B.A.1
Quelle, F.W.2
Silvennoinen, O.3
-
21
-
-
0033578334
-
Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction
-
Li C, Friedman JM. Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction. Proc Natl Acad Sci USA 1999; 96:9677-82.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 9677-9682
-
-
Li, C.1
Friedman, J.M.2
-
22
-
-
0032568515
-
Enhancing leptin response by preventing SH2- containing phosphatase 2 interaction with Ob receptor
-
Carpenter LR, Farruggella TJ, Symes A, Karow ML, Yancopoulos GD, Stahl N. Enhancing leptin response by preventing SH2- containing phosphatase 2 interaction with Ob receptor. Proc Natl Acad Sci USA 1998; 95:6061-6.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6061-6066
-
-
Carpenter, L.R.1
Farruggella, T.J.2
Symes, A.3
Karow, M.L.4
Yancopoulos, G.D.5
Stahl, N.6
-
23
-
-
0031010408
-
Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues
-
Fei H, Okano HJ, Li C, et al. Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proc Natl Acad Sci USA 1997; 94:7001-5.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7001-7005
-
-
Fei, H.1
Okano, H.J.2
Li, C.3
-
25
-
-
0032508682
-
Biological action of leptin as an angiogenic factor
-
Sierra-Honigmann MR, Nath AK, Murakami C, et al. Biological action of leptin as an angiogenic factor. Science 1998; 281:1683-6.
-
(1998)
Science
, vol.281
, pp. 1683-1686
-
-
Sierra-Honigmann, M.R.1
Nath, A.K.2
Murakami, C.3
-
26
-
-
0032971218
-
Leptin promotes aggregation of human platelets via the long form of its receptor
-
Nakata M, Yada T, Soejima N, Maruyama I. Leptin promotes aggregation of human platelets via the long form of its receptor. Diabetes 1999; 48:426-9.
-
(1999)
Diabetes
, vol.48
, pp. 426-429
-
-
Nakata, M.1
Yada, T.2
Soejima, N.3
Maruyama, I.4
-
27
-
-
0032572722
-
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
-
Lord GM, Matarese G, Howard JK, Baker RJ, Bloom SR, Lechler RI. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 1998; 394:897-901.
-
(1998)
Nature
, vol.394
, pp. 897-901
-
-
Lord, G.M.1
Matarese, G.2
Howard, J.K.3
Baker, R.J.4
Bloom, S.R.5
Lechler, R.I.6
-
28
-
-
0034464866
-
Systemically and topically administered leptin both accelerate wound healing in diabetic ob/ob mice
-
Ring BD, Scully S, Davis CR, et al. Systemically and topically administered leptin both accelerate wound healing in diabetic ob/ob mice. Endocrinology 2000; 141:446-9.
-
(2000)
Endocrinology
, vol.141
, pp. 446-449
-
-
Ring, B.D.1
Scully, S.2
Davis, C.R.3
-
29
-
-
0033198793
-
Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis
-
Sano S, Itami S, Takeda K, et al. Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis. EMBO J 1999; 18:4657-68.
-
(1999)
EMBO J
, vol.18
, pp. 4657-4668
-
-
Sano, S.1
Itami, S.2
Takeda, K.3
-
30
-
-
0029860791
-
Modulation of insulin activities by leptin
-
Cohen B, Novick D, Rubinstein M. Modulation of insulin activities by leptin. Science 1996; 274:1185-8.
-
(1996)
Science
, vol.274
, pp. 1185-1188
-
-
Cohen, B.1
Novick, D.2
Rubinstein, M.3
-
32
-
-
0031467631
-
Direct effects of leptin on brown and white adipose tissue
-
Siegrist-Kaiser CA, Pauli V, Juge-Aubry CE, et al. Direct effects of leptin on brown and white adipose tissue. J Clin Invest 1997; 100:2858-64.
-
(1997)
J Clin Invest
, vol.100
, pp. 2858-2864
-
-
Siegrist-Kaiser, C.A.1
Pauli, V.2
Juge-Aubry, C.E.3
-
33
-
-
0033580938
-
Novel form of lipolysis induced by leptin
-
Wang MY, Lee Y, Unger RH. Novel form of lipolysis induced by leptin. J Biol Chem 1999; 274:17541-4.
-
(1999)
J Biol Chem
, vol.274
, pp. 17541-17544
-
-
Wang, M.Y.1
Lee, Y.2
Unger, R.H.3
-
35
-
-
0030965884
-
Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion
-
Emilsson V, Liu YL, Cawthorne MA, Morton NM, Davenport M. Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion. Diabetes 1997; 46:313-6.
-
(1997)
Diabetes
, vol.46
, pp. 313-316
-
-
Emilsson, V.1
Liu, Y.L.2
Cawthorne, M.A.3
Morton, N.M.4
Davenport, M.5
-
36
-
-
0032908196
-
Leptin signalling in pancreatic islets and clonal insulin-secreting cells
-
Morton NM, Emilsson V de, Groot P, Pallett AL, Cawthorne MA. Leptin signalling in pancreatic islets and clonal insulin-secreting cells. J Mol Endocrinol 1999; 22:173-84.
-
(1999)
J Mol Endocrinol
, vol.22
, pp. 173-184
-
-
Morton, N.M.1
De Emilsson, V.2
Groot, P.3
Pallett, A.L.4
Cawthorne, M.A.5
-
37
-
-
0030137757
-
Leptin receptor missense mutation in the fatty Zucker rat
-
Phillips MS, Liu Q, Hammond HA, et al. Leptin receptor missense mutation in the fatty Zucker rat. Nature Genetics 1996; 13:18-9.
-
(1996)
Nature Genetics
, vol.13
, pp. 18-19
-
-
Phillips, M.S.1
Liu, Q.2
Hammond, H.A.3
-
38
-
-
9344241376
-
Phenotype of fatty due to Gln269pro mutation in the leptin receptor (Lepr)
-
Chua SC, Jr White, DW Wu-Peng, XS Liu, SM Okada N, Leibel RL. Phenotype of fatty due to Gln269pro mutation in the leptin receptor (Lepr). Diabetes 1996; 45:1141-3.
-
(1996)
Diabetes
, vol.45
, pp. 1141-1143
-
-
Chua Jr., S.C.1
White, D.W.2
Wu-Peng, X.S.3
Liu, S.M.4
Okada, N.5
Leibel, R.L.6
-
39
-
-
0030590070
-
Substitution at codon 269 (glutamine → proline) of the leptin receptor (OB-R) cDNA is the only mutation found in the Zucker fatty (fa/fa) rat
-
Iida M, Murakami T, Ishida K, Mizuno A, Kuwajima M, Shima K. Substitution at codon 269 (glutamine → proline) of the leptin receptor (OB-R) cDNA is the only mutation found in the Zucker fatty (fa/fa) rat. Biochem Biophys Res Commun 1996; 224:597-604.
-
(1996)
Biochem Biophys Res Commun
, vol.224
, pp. 597-604
-
-
Iida, M.1
Murakami, T.2
Ishida, K.3
Mizuno, A.4
Kuwajima, M.5
Shima, K.6
-
40
-
-
0032541045
-
Altered cell surface expression and signaling of leptin receptors containing the fatty mutation
-
Grouse JA, Elliott GE, Burgess TL, et al. Altered cell surface expression and signaling of leptin receptors containing the fatty mutation. J Biol Chem 1998; 273:18365-73.
-
(1998)
J Biol Chem
, vol.273
, pp. 18365-18373
-
-
Grouse, J.A.1
Elliott, G.E.2
Burgess, T.L.3
-
41
-
-
0030871847
-
Beta-cell function in normal rats made chronically hyperleptinemic by adenovirus-leptin gene therapy
-
Koyama K, Chen G, Wang MY, et al. beta-cell function in normal rats made chronically hyperleptinemic by adenovirus-leptin gene therapy. Diabetes 1997; 46:1276-80.
-
(1997)
Diabetes
, vol.46
, pp. 1276-1280
-
-
Koyama, K.1
Chen, G.2
Wang, M.Y.3
-
42
-
-
0031950686
-
OB-Rb gene transfer to leptin-resistant islets reverses diabetogenic phenotype
-
Wang MY, Koyama K, Shimabukuro M, Newgard CB, Unger RH. OB-Rb gene transfer to leptin-resistant islets reverses diabetogenic phenotype. Proc Natl Acad Sci USA 1998; 95:714-8.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 714-718
-
-
Wang, M.Y.1
Koyama, K.2
Shimabukuro, M.3
Newgard, C.B.4
Unger, R.H.5
-
43
-
-
0032482988
-
Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression
-
Shimabukuro M, Wang MY, Zhou YT, Newgard CB, Unger RH. Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression. Proc Natl Acad Sci USA 1998; 95:9558-61.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9558-9561
-
-
Shimabukuro, M.1
Wang, M.Y.2
Zhou, Y.T.3
Newgard, C.B.4
Unger, R.H.5
-
44
-
-
0032578484
-
Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion
-
Wang MY, Koyama K, Shimabukuro M, Mangelsdorf D, Newgard CB, Unger RH. Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion. Proc Natl Acad Sci USA 1998; 95:11921-6.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 11921-11926
-
-
Wang, M.Y.1
Koyama, K.2
Shimabukuro, M.3
Mangelsdorf, D.4
Newgard, C.B.5
Unger, R.H.6
-
45
-
-
0033514956
-
Regulation of fatty acid homeostasis in cells: Novel role of leptin
-
Unger RH, Zhou YT, Orci L. Regulation of fatty acid homeostasis in cells: novel role of leptin. Proc Natl Acad Sci USA 1999; 96:2327-32.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2327-2332
-
-
Unger, R.H.1
Zhou, Y.T.2
Orci, L.3
-
46
-
-
0031550523
-
A short form of leptin receptor performs signal transduction
-
Murakami T, Yamashita T, Iida M, Kuwajima M, Shima K. A short form of leptin receptor performs signal transduction. Biochem Biophys Res Commun 1997; 231:26-9.
-
(1997)
Biochem Biophys Res Commun
, vol.231
, pp. 26-29
-
-
Murakami, T.1
Yamashita, T.2
Iida, M.3
Kuwajima, M.4
Shima, K.5
-
47
-
-
0032577194
-
Leptin receptor signal transduction: OBRa and OBRb of fa type
-
Yamashita T, Murakami T, Otani S, Kuwajima M, Shima K. Leptin receptor signal transduction: OBRa and OBRb of fa type. Biochem Biophys Res Commun 1998; 246:752-9.
-
(1998)
Biochem Biophys Res Commun
, vol.246
, pp. 752-759
-
-
Yamashita, T.1
Murakami, T.2
Otani, S.3
Kuwajima, M.4
Shima, K.5
-
48
-
-
0031436148
-
Divergent signaling capacities of the long and short isoforms of the leptin receptor
-
Bjorbaek C, Uotani S, da Silva B, Flier JS. Divergent signaling capacities of the long and short isoforms of the leptin receptor. J Biol Chem 1997; 272:32686-95.
-
(1997)
J Biol Chem
, vol.272
, pp. 32686-32695
-
-
Bjorbaek, C.1
Uotani, S.2
Da Silva, B.3
Flier, J.S.4
-
49
-
-
0030793449
-
Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding
-
DeVos R, Guisez Y, Van der Heyden J, et al. Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding. J Biol Chem 1997; 272:18304-10.
-
(1997)
J Biol Chem
, vol.272
, pp. 18304-18310
-
-
DeVos, R.1
Guisez, Y.2
Van Der Heyden, J.3
-
50
-
-
0031040793
-
Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization
-
White DW, Kuropatwinski KK, Devos R, Baumann H, Tartaglia, LA. Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization. J Biol Chem 1997; 272:4065-71.
-
(1997)
J Biol Chem
, vol.272
, pp. 4065-4071
-
-
White, D.W.1
Kuropatwinski, K.K.2
Devos, R.3
Baumann, H.4
Tartaglia, L.A.5
-
51
-
-
0030010388
-
Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
-
Chehab FF, Lim ME, Lu R. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nature Genetics 1996; 12:318-20.
-
(1996)
Nature Genetics
, vol.12
, pp. 318-320
-
-
Chehab, F.F.1
Lim, M.E.2
Lu, R.3
-
52
-
-
0031014413
-
Early onset of reproductive function in normal female mice treated with leptin
-
Chehab FF, Mounzih K, Lu R, Lim ME. Early onset of reproductive function in normal female mice treated with leptin. Science 1997; 275:88-90.
-
(1997)
Science
, vol.275
, pp. 88-90
-
-
Chehab, F.F.1
Mounzih, K.2
Lu, R.3
Lim, M.E.4
-
53
-
-
0033536008
-
Leptin actions on food intake and body temperature are mediated by IL-1
-
Luheshi GN, Gardner JD, Rushforth DA, Loudon AS, Rothwell NJ. Leptin actions on food intake and body temperature are mediated by IL-1. Proc Natl Acad Sci USA 1999; 96:7047-52.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7047-7052
-
-
Luheshi, G.N.1
Gardner, J.D.2
Rushforth, D.A.3
Loudon, A.S.4
Rothwell, N.J.5
-
54
-
-
0141737573
-
Leptin inhibits bone formation through a hypothalamic relay: A central control of bone mass
-
Ducy P, Amling M, Takeda S, et al. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell 2000; 100:197-207.
-
(2000)
Cell
, vol.100
, pp. 197-207
-
-
Ducy, P.1
Amling, M.2
Takeda, S.3
-
55
-
-
0032014836
-
A leptin missense mutation associated with hypogonadism and morbid obesity
-
Strobel A, Camoin TIL, Ozata M, Strosberg AD. A leptin missense mutation associated with hypogonadism and morbid obesity. Nature Genetics 1998; 18:213-5.
-
(1998)
Nature Genetics
, vol.18
, pp. 213-215
-
-
Strobel, A.1
Camoin, T.I.L.2
Ozata, M.3
Strosberg, A.D.4
-
56
-
-
0030878110
-
Congenital leptin deficiency is associated with severe early-onset obesity in humans
-
Montague CT, Farooqi IS, Whitehead JP, et al. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 1997; 387:903-8.
-
(1997)
Nature
, vol.387
, pp. 903-908
-
-
Montague, C.T.1
Farooqi, I.S.2
Whitehead, J.P.3
-
57
-
-
0344450708
-
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
-
Clement K, Vaisse C, Lahlou N, et al. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature 1998; 392:398-401.
-
(1998)
Nature
, vol.392
, pp. 398-401
-
-
Clement, K.1
Vaisse, C.2
Lahlou, N.3
|