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Volumn 22, Issue 2, 1999, Pages 173-184

Leptin signalling in pancreatic islets and clonal insulin-secreting cells

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; MITOGEN ACTIVATED PROTEIN KINASE; STAT3 PROTEIN;

EID: 0032908196     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.0.0220173     Document Type: Article
Times cited : (52)

References (53)
  • 1
    • 0027235323 scopus 로고
    • Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells
    • Ammälä C, Ashcroft FM & Rorsman P 1993 Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells. Nature 363 356-358.
    • (1993) Nature , vol.363 , pp. 356-358
    • Ammälä, C.1    Ashcroft, F.M.2    Rorsman, P.3
  • 3
    • 0025094662 scopus 로고
    • Neuroendocrine control of the development of obesity: Understanding gained from studies of experimental animal models
    • Bray GA, Fisler J & York DA 1990 Neuroendocrine control of the development of obesity: understanding gained from studies of experimental animal models. Frontiers in Neuroendocrinology 11 128-181.
    • (1990) Frontiers in Neuroendocrinology , vol.11 , pp. 128-181
    • Bray, G.A.1    Fisler, J.2    York, D.A.3
  • 6
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
    • Campfield LA, Smith FJ, Guisez Y, Davos R & Burn P 1995 Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269 546-549.
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Guisez, Y.3    Davos, R.4    Burn, P.5
  • 7
    • 0031001932 scopus 로고    scopus 로고
    • Persistently enhanced sensitivity of pancreatic islets from ob/ob mice to PKC-stimulated insulin secretion
    • Endocrinology and Metabolism 35
    • Chen N & Romsos DR 1997 Persistently enhanced sensitivity of pancreatic islets from ob/ob mice to PKC-stimulated insulin secretion. American Journal of Physiology 272 (Endocrinology and Metabolism 35) E304-E311.
    • (1997) American Journal of Physiology , vol.272
    • Chen, N.1    Romsos, D.R.2
  • 9
    • 0030955188 scopus 로고    scopus 로고
    • Leptin constrains acetylcholine-induced insulin secretion from pancreatic islets of ob/ob mice
    • Chen NG, Swick AG & Romsos DR 1997 Leptin constrains acetylcholine-induced insulin secretion from pancreatic islets of ob/ob mice. Journal of Clinical Investigation 100 1174-1179.
    • (1997) Journal of Clinical Investigation , vol.100 , pp. 1174-1179
    • Chen, N.G.1    Swick, A.G.2    Romsos, D.R.3
  • 10
    • 0030772458 scopus 로고    scopus 로고
    • STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation
    • Chung J, Uchida E, Grammer TC & Blenis J 1997 STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation. Molecular and Cellular Biology 17 6508-6516.
    • (1997) Molecular and Cellular Biology , vol.17 , pp. 6508-6516
    • Chung, J.1    Uchida, E.2    Grammer, T.C.3    Blenis, J.4
  • 11
    • 0018139377 scopus 로고
    • Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice
    • Coleman DL 1978 Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 14 141-148.
    • (1978) Diabetologia , vol.14 , pp. 141-148
    • Coleman, D.L.1
  • 12
    • 0024456530 scopus 로고
    • Comparison of effect of phorbol esters and glucose on protein kinase C activation and insulin secretion in pancreatic islets
    • Easom RA, Hughes JH, Landt M, Wolf BA, Turk J & McDaniel ML 1989 Comparison of effect of phorbol esters and glucose on protein kinase C activation and insulin secretion in pancreatic islets. Biochemical Journal 264 27-33.
    • (1989) Biochemical Journal , vol.264 , pp. 27-33
    • Easom, R.A.1    Hughes, J.H.2    Landt, M.3    Wolf, B.A.4    Turk, J.5    McDaniel, M.L.6
  • 13
    • 0030965884 scopus 로고    scopus 로고
    • Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion
    • Emilsson V, Liu Y-L, Cawthorne MA, Morton NM & Davenport M 1997 Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion. Diabetes 46 313-316.
    • (1997) Diabetes , vol.46 , pp. 313-316
    • Emilsson, V.1    Liu, Y.-L.2    Cawthorne, M.A.3    Morton, N.M.4    Davenport, M.5
  • 15
    • 0031435277 scopus 로고    scopus 로고
    • Interaction of GLP-1 and leptin at rat pancreatic β-cells: Effects on insulin secretion and signal transduction
    • Fehmann H-C, Bode H-P, Ebert T, Karl A & Goke B 1997b Interaction of GLP-1 and leptin at rat pancreatic β-cells: effects on insulin secretion and signal transduction. Hormone and Metabolic Research 29 572-576.
    • (1997) Hormone and Metabolic Research , vol.29 , pp. 572-576
    • Fehmann, H.-C.1    Bode, H.-P.2    Ebert, T.3    Karl, A.4    Goke, B.5
  • 17
    • 0030956390 scopus 로고    scopus 로고
    • The leptin receptor activates Janus kinase 2 and signals for proliferation in a factor-dependent cell line
    • Ghilardi N & Skoda RC 1997 The leptin receptor activates Janus kinase 2 and signals for proliferation in a factor-dependent cell line. Molecular Endocrinology 11 393-399.
    • (1997) Molecular Endocrinology , vol.11 , pp. 393-399
    • Ghilardi, N.1    Skoda, R.C.2
  • 19
    • 0030846483 scopus 로고    scopus 로고
    • Multisite regulation of insulin secretion by cAMP-increasing agonists - Evidence that glucagon-like peptide 1 and glucagon act via distinct receptors
    • Gromada J, Ding WG, Barg S, Renstrom E & Rorsman P 1997 Multisite regulation of insulin secretion by cAMP-increasing agonists - evidence that glucagon-like peptide 1 and glucagon act via distinct receptors. European Journal of Physiology 434 515-524.
    • (1997) European Journal of Physiology , vol.434 , pp. 515-524
    • Gromada, J.1    Ding, W.G.2    Barg, S.3    Renstrom, E.4    Rorsman, P.5
  • 20
    • 0031026938 scopus 로고    scopus 로고
    • Non-insulin-dependent-diabetes mellitus - A collision between thrifty genes and an affluent society
    • Groop LC & Tuomi T 1997 Non-insulin-dependent-diabetes mellitus - a collision between thrifty genes and an affluent society. Annals of Medicine 29 37-53.
    • (1997) Annals of Medicine , vol.29 , pp. 37-53
    • Groop, L.C.1    Tuomi, T.2
  • 23
    • 0027473729 scopus 로고
    • Pancreatic beta cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide 1(7-37)
    • Holz GG, Kuhtreiber WM & Habener JF 1993 Pancreatic beta cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide 1(7-37). Nature 361 362-365.
    • (1993) Nature , vol.361 , pp. 362-365
    • Holz, G.G.1    Kuhtreiber, W.M.2    Habener, J.F.3
  • 24
    • 0031590254 scopus 로고    scopus 로고
    • Rat insulinoma-derived pancreatic β-cells express a functional leptin receptor that mediates a proliferative response
    • Islam MS, Morton NM, Hansson A & Emilsson V 1997 Rat insulinoma-derived pancreatic β-cells express a functional leptin receptor that mediates a proliferative response. Biochemical and Biophysical Research Communications 238 851-855.
    • (1997) Biochemical and Biophysical Research Communications , vol.238 , pp. 851-855
    • Islam, M.S.1    Morton, N.M.2    Hansson, A.3    Emilsson, V.4
  • 25
    • 0030946515 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription-3 (STAT-3) is constitutively activated in normal, self-renewing B-1 cells but only inducibly expressed in conventional B lymphocytes
    • Karras JG, Wang ZH, Huo L, Howard RG, Frank DA & Rothstein TL 1997 Signal transducer and activator of transcription-3 (STAT-3) is constitutively activated in normal, self-renewing B-1 cells but only inducibly expressed in conventional B lymphocytes. Journal of Experimental Medicine 185 1035-1042.
    • (1997) Journal of Experimental Medicine , vol.185 , pp. 1035-1042
    • Karras, J.G.1    Wang, Z.H.2    Huo, L.3    Howard, R.G.4    Frank, D.A.5    Rothstein, T.L.6
  • 27
    • 0030871847 scopus 로고    scopus 로고
    • Beta-cell function in normal rats made chronically hyperleptinemic by adenovirus-leptin gene therapy
    • Koyama K, Chen GX, Wang MY, Lee Y, Shimabukuro M, Newgard CB & Unger RH 1997 Beta-cell function in normal rats made chronically hyperleptinemic by adenovirus-leptin gene therapy. Diabetes 46 1276-1280.
    • (1997) Diabetes , vol.46 , pp. 1276-1280
    • Koyama, K.1    Chen, G.X.2    Wang, M.Y.3    Lee, Y.4    Shimabukuro, M.5    Newgard, C.B.6    Unger, R.H.7
  • 32
    • 0031915043 scopus 로고    scopus 로고
    • Effects of leptin on insulin secretion from isolated rat pancreatic islets
    • Ookooma M, Ookooma K & York DA 1998 Effects of leptin on insulin secretion from isolated rat pancreatic islets. Diabetes 47 219-223.
    • (1998) Diabetes , vol.47 , pp. 219-223
    • Ookooma, M.1    Ookooma, K.2    York, D.A.3
  • 33
    • 0022529019 scopus 로고
    • The insulin cell: Its cellular environment and how it processes (pro)insulin
    • Orci L 1986 The insulin cell: its cellular environment and how it processes (pro)insulin. Diabetes Metabolism Reviews 2 71-106.
    • (1986) Diabetes Metabolism Reviews , vol.2 , pp. 71-106
    • Orci, L.1
  • 36
    • 0029691864 scopus 로고    scopus 로고
    • An integrated view of beta cell dysfunction in type II diabetes
    • Poitout V & Robertson RP 1996 An integrated view of beta cell dysfunction in type II diabetes. Annual Review of Medicine 47 69-83.
    • (1996) Annual Review of Medicine , vol.47 , pp. 69-83
    • Poitout, V.1    Robertson, R.P.2
  • 37
    • 0031793899 scopus 로고    scopus 로고
    • Inhibition of insulin secretion by leptin in normal rodent islets of Langerhans
    • Poitout Y, Rouault C, Guerre-Millo M, Briaud I & Reach G 1998 Inhibition of insulin secretion by leptin in normal rodent islets of Langerhans. Endocrinology 139 822-826.
    • (1998) Endocrinology , vol.139 , pp. 822-826
    • Poitout, Y.1    Rouault, C.2    Guerre-Millo, M.3    Briaud, I.4    Reach, G.5
  • 39
    • 0030748260 scopus 로고    scopus 로고
    • Signal transduction mechanisms in nutrient-induced insulin secretion
    • Prentki M, Tornheim K & Corkey BE 1997 Signal transduction mechanisms in nutrient-induced insulin secretion. Diabetologia 40 S32-S41.
    • (1997) Diabetologia , vol.40
    • Prentki, M.1    Tornheim, K.2    Corkey, B.E.3
  • 48
    • 0031040793 scopus 로고    scopus 로고
    • Leptin receptor (OB-R) signaling - Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerisation
    • White DW, Kuropatwinski KK, Devos R, Baumann H & Tartaglia LA 1997 Leptin receptor (OB-R) signaling - cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerisation. Journal of Biological Chemistry 272 4065-4071.
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 4065-4071
    • White, D.W.1    Kuropatwinski, K.K.2    Devos, R.3    Baumann, H.4    Tartaglia, L.A.5
  • 52
    • 0029797647 scopus 로고    scopus 로고
    • Regulation of insulin secretion by phospholipase C
    • Endocrinology and Metabolism 34
    • Zawalich WS & Zawalich KC 1996 Regulation of insulin secretion by phospholipase C. American Journal of Physiology 271 (Endocrinology and Metabolism 34) E409-E416.
    • (1996) American Journal of Physiology , vol.271
    • Zawalich, W.S.1    Zawalich, K.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.