TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2

Nature

Volumn 417, Issue 6891, 2002, Pages 861-866

  Pasparakis, Manolis ^a,b   Courtois, Gilles ^c   Hafner, Martin ^a,g   Schmidt Supprian, Marc ^a,f   Nenci, Arianna ^b   Toksoy, Atiye ^d   Krampert, Monika ^e   Goebeler, Matthias ^d   Gillitzer, Reinhard ^d   Israel, Alain ^c   Krieg, Thomas ^a   Rajewsky, Klaus ^a,f   Haase, Ingo ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY EMBL   (Italy)

^c INSTITUT PASTEUR   (France)

^d UNIVERSITY OF WÜRZBURG   (Germany)

^e ETH ZURICH   (Switzerland)

^f HARVARD MEDICAL SCHOOL   (United States)

^g HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; CELLS; GENES; MUTAGENESIS; PROTEINS; TUMORS;

HYPERPROLIFERATION;

DERMATITIS;

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TUMOR NECROSIS FACTOR;

BIOLOGY; SKIN DISORDER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; EPIDERMIS HYPERPLASIA; GENE DELETION; GENE TARGETING; GENOTYPE; HETEROZYGOSITY; IMMUNE SYSTEM; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INFLAMMATION; KERATINOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SKIN INFLAMMATION; T LYMPHOCYTE; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL DIVISION; EPIDERMIS; GENE DELETION; I-KAPPA B KINASE; IN SITU HYBRIDIZATION; IN SITU NICK-END LABELING; INFLAMMATION; KERATINOCYTES; MICE; MICE, KNOCKOUT; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER; SKIN DISEASES; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; MUS MUSCULUS;

EID: 0037142027     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature00820     Document Type: Article

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