Distinct protein interaction domains and protein spreading in a complex centromere

Genes and Development

Volumn 14, Issue 7, 2000, Pages 783-791

  Partridge, Janet F ^a   Borgstrøm, Britta ^b   Allshire, Robin C ^a  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

^b Biotechnology Group 1   (Denmark)

Author keywords

Centromere; Chromatin immunoprecipitation; Chromodomain; Schizosaccharomyces pombe; Silencing; Spreading

Indexed keywords

ARTICLE; CENTROMERE; CHROMOSOME SEGREGATION; GENE MAPPING; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN RNA BINDING; SACCHAROMYCES;

CELL CYCLE PROTEINS; CENTROMERE; CHROMOSOME MAPPING; DNA, FUNGAL; FUNGAL PROTEINS; GENE SILENCING; GENES, FUNGAL; HETEROCHROMATIN; REPETITIVE SEQUENCES, NUCLEIC ACID; RNA, TRANSFER; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; TRANSCRIPTION FACTORS;

EUKARYOTA; FUNGI; SACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE;

EID: 0034175605     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Aagaard, L., G. Laible, P. Selenko, M. Schmid, R. Dorn, G. Schotta, S. Kuhfittig, A. Wolf, A. Lebersorger, P.B. Singh et al. 1999. Functional mammalian homologues of the Drosophila PEV modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31. EMBO J. 18: 1923-1938.
2. Allshire, R.C. 1996. Transcriptional silencing in the fission yeast: A manifestation of higher order chromosome structure and functions. In Epigenetic mechanisms of gene regulation. pp. 443-466. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
3. Allshire, R.C., J.-P. Javerzat, N.J. Redhead, and G. Cranston. 1994. Position effect variegation at fission yeast centromeres. Cell 76: 157-169.
4. Allshire, R.C., E.R. Nimmo, K. Ekwall, J.-P. Javerzat, and G. Cranston. 1995. Mutations derepressing silent domains within fission yeast centromeres disrupt chromosome segregation. Genes & Dev. 9: 218-233.
5. Baum, M., V.K. Ngan, and L. Clarke. 1994. The centromeric K-type repeat and the central core are together sufficient to establish a functional Schizosaccharomyces pombe centromere. Mol. Biol. Cell 5: 747-761.
6. Brown, K.E., M.A. Barnett, C. Burgtorf, P. Shaw, V.J. Buckle, and W.R. Brown. 1994. Dissecting the centromere of the human Y chromosome with cloned telomeric DNA. Hum. Mol. Genet. 3: 1227-1237.
7. Clarke, L., H. Amstutz, B. Fishel, and J. Carbon. 1986. Analysis of centromeric DNA in the fission yeast Schizosaccharomyces pombe. Proc. Natl. Acad. Sci. 83: 8253-8257.
8. + is required for chromosome segregation and shows a genetic interaction with alpha-tubulin. Nucleic Acids Res. 26: 4222-4229.
9. Donze, D., C.R. Adams, J. Rine, and R.T. Kamakaka. 1999. The boundaries of the silenced HMR domain in Saccharomyces cerevisiae. Genes & Dev. 13: 698-708.
10. Ekwall, K. and J.F. Partridge. 1999. Fission yeast chromosome analysis: Fluorescence in situ hybridisation (FISH) and chromatin immunoprecipitation (CHIP). In Chromosome structural analysis, a practical approach (ed. W.A. Bickmore), pp. 39-57. Oxford University Press, Oxford, UK.
11. Ekwall, K., J.-P. Javerzat, A. Lorentz, H. Schmidt, G. Cranston, and R.C. Allshire. 1995. The chromodomain protein Swi6: A key component at fission yeast centromeres. Science 269: 1429-1431.
12. + disrupt the localization of the chromo domain protein Swi6p and impair centromere function. J. Cell Sci. 109: 2637-2648.
13. Ekwall, K., T. Olsson, B.M. Turner, G. Cranston, and R.C. Allshire. 1997. Transient inhibition of histone deacetylation alters the structural and functional imprint at fission yeast centromeres. Cell 91: 1021-1032.
14. Espelin, C.W., K.B. Kaplan, and P.K. Sorger. 1997. Probing the architecture of a simple kinetochore using DNA-protein crosslinking. J. Cell Biol. 139: 1383-1396.
15. Fishel, B., H. Amstutz, M. Baum, J. Carbon, and L. Clarke. 1988. Structural organization and functional analysis of centromeric DNA in the fission yeast Schizosaccharomyces pombe. Mol. Cell. Biol. 8: 754-763.
16. Gorman, M., A. Franke, and B.S. Baker. 1995. Molecular characterization of the male-specific lethal-3 gene and investigations of the regulation of dosage compensation in Drosophila. Development 121: 463-475.
17. Goshima, G., S. Saitoh, and M. Yanagida. 1999. Proper metaphase spindle length is determined by centromere proteins Mis12 and Mis6 required for faithful chromosome segregation. Genes & Dev. 13: 1664-1677.
18. Grunstein, M. 1998. Yeast heterochromatin: Regulation of its assembly and inheritance by histones. Cell 93: 325-328.
19. Hahnenberger, K.M., J. Carbon, and L. Clarke. 1991. Identification of DNA regions required for mitotic and meiotic functions within the centromere of Schizosaccharomyces pombe. Mol. Cell. Biol. 11: 2206-2215.
20. Hecht, A., T. Laroche, S. Strahl-Bolsinger, S.M. Gasser, and M. Grunstein. 1995. Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: A molecular model for the formation of heterochromatin in yeast. Cell 80: 583-592.
21. Hecht, A., S. Strahl-Bolsinger, and M. Grunstein. 1996. Spreading of transcriptional repressor SIR3 from telomeric heterochromatin. Nature 383: 92-96.
22. Hilfiker, A., D. Hilfiker-Kleiner, A. Pannuti, and J.C. Lucchesi. 1997. mof, a putative acetyl transferase gene related to the Tip60 and MOZ human genes and to the SAS genes of yeast, is required for dosage compensation in Drosophila. EMBO J. 16: 2054-2060.
23. Ivanova, A.V., M.J. Bonaduce, S.V. Ivanov, and A.J.S. Klar. 1998. The chromo and SET domains of the Clr4 protein are essential for silencing in fission yeast. Nat. Genet. 19: 192-195.
24. Karpen, G.H. 1994. Position effect variegation and the new biology of heterochromatin. Curr. Opin. Genet. Dev. 4: 281-291.
25. Keeney, J.B. and J.D. Boeke. 1994. Efficient targeted integration at leu1-32 and ura4-294 in Schizosaccharomyces pombe. Genetics 136: 849-856.
26. Kelley, R.L., V.H. Meller, P.R. Gordadze, G. Roman, R.L. Davis, and M.I. Kuroda. 1999. Epigenetic spreading of the Drosophila dosage compensation complex from roX RNA genes into flanking chromatin. Cell 98: 513-522.
27. Lee, C., R. Wevrick, R.B. Fisher, M.A. Ferguson-Smith, and C.C. Lin. 1997. Human centromeric DNAs. Hum. Genet. 100: 291-304
28. Meluh, P.B. and D. Koshland. 1997. Budding yeast centromere composition and assembly as revealed by in vivo cross-linking. Genes & Dev. 11: 3401-3412.
29. Meluh, P.B., P. Yang, L. Glowczewski, D. Koshland, and M.M. Smith. 1998. Cse4p is a component of the core centromere of Saccharomyces cerevisiae. Cell 94: 607-613.
30. Moehrle, A. and R. Paro. 1994. Spreading the silence: Epigenetic transcriptional regulation during Drosophila development. Dev. Genet. 15: 478-484.
31. Murphy, T.D. and G.H. Karpen. 1995. Localization of centromere function in a Drosophila minichromosome. Cell 82: 599-609.
32. Murphy, T.D. and G.H. Karpen. 1998. Centromeres take flight: Alpha satellite and the quest for the human centromere. Cell 93: 317-320.
33. Nakaseko, Y., Y. Adachi, S. Funahashi, O. Niwa, and M. Yanagida. 1986. Chromosome walking shows a highly repetitive sequence present in all the centromere regions of fission yeast. EMBO J. 5: 1011-1021.
34. Nakaseko, Y., N. Kinoshita, and M. Yanagida. 1987. A novel sequence common to the centromere regions of Schizosaccharomyces pombe chromosomes. Nucleic Acids Res. 15: 4705-4715.
35. Saitoh, S., K. Takahashi, and M. Yanagida. 1997. Mis6, a fission yeast inner centromere protein, acts during G1/S and forms specialized chromatin required for equal segregation. Cell 90: 131-143.
36. Strahl-Bolsinger, S., A. Hecht, K. Luo, and M. Grunstein. 1997. SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes & Dev. 11: 83-93.
37. Sun, X., J. Wahlstrom, and G.H. Karpen. 1997. Molecular structure of a functional Drosophila centromere. Cell 91: 1007-1019.
38. Takahashi, K., S. Murakami, Y. Chikashige, O. Niwa, and M. Yanagida. 1991. A large number of tRNA genes are symmetrically located in fission yeast centromeres. J. Mol. Biol. 218: 13-17.
39. Takahashi, K., H. Yamada, and M. Yanagida. 1994. Fission yeast minichromosome loss mutants mis cause lethal aneuploidy and replication abnormality. Mol. Biol. Cell 5: 1145-1158.
40. Tschiersch, B., A. Hofmann, V. Krauss, R. Dorn, G. Korge, and G. Reuter. 1994. The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var)3-9 combines domains of antagonistic regulators of homeotic gene complexes. EMBO J. 13: 3822-3831.
41. Weiler, K.S. and B.T. Wakimoto. 1995. Heterochromatin and gene expression in Drosophila. Annu. Rev. Genet. 29: 577-605.
42. Williams, B.C., T.D. Murphy, M.L. Goldberg, and G.H. Karpen. 1998. Neocentromere activity of structurally acentric minichromosomes in Drosophila. Nat. Genet. 18: 30-37.