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Volumn 44, Issue SUPPL. 3, 2003, Pages

Molecular pathogenesis of non-Hodgkin's lymphoma: The role of Bcl-6

Author keywords

Bcl 6; Diffuse large B cell lymphoma; Germinal center; Non Hodgkin's lymphoma; Pathogenesis; Somatic hypermutation

Indexed keywords

HISTONE; HISTONE DEACETYLASE; NICOTINAMIDE; PHOSPHOPROTEIN; PROTEIN BCL 6; SILENT INFORMATION REGULATOR PROTEIN 2; TRANSCRIPTION FACTOR; TRICHOSTATIN A; VORINOSTAT; ZINC FINGER PROTEIN;

EID: 1042303640     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.1080/10428190310001621588     Document Type: Review
Times cited : (115)

References (67)
  • 2
    • 0029902171 scopus 로고    scopus 로고
    • "Primary vs. secondary neoplasia associated chromosomal abnormalities - Balanced rearrangements vs. genomic imbalance?"
    • Johansson, B., Mertens, F. and Mitelman, F. (1996) "Primary vs. secondary neoplasia associated chromosomal abnormalities - balanced rearrangements vs. genomic imbalance?", Genes, Chromosomes & Cancer, 16, 155-163.
    • (1996) Genes, Chromosomes & Cancer , vol.16 , pp. 155-163
    • Johansson, B.1    Mertens, F.2    Mitelman, F.3
  • 3
    • 0030999555 scopus 로고    scopus 로고
    • "A breakpoint map of recurrent chromosomal rearrangements in human neoplasia"
    • Mitelman, F., Mertens, F. and Johansson, B. (1997) "A breakpoint map of recurrent chromosomal rearrangements in human neoplasia", Nature Genetics, 15, 417-474.
    • (1997) Nature Genetics , vol.15 , pp. 417-474
    • Mitelman, F.1    Mertens, F.2    Johansson, B.3
  • 5
    • 0033151510 scopus 로고    scopus 로고
    • "The apoptosis inhibitor gene AP12 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas"
    • Dierlamm, J., Baens, M., Wlodarska, I., Stefanova-Ouzounova, M., Hernandez, J.M., Hossfeld, D.K., et al. (1999) "The apoptosis inhibitor gene AP12 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas", Blood, 93, 3601-3609.
    • (1999) Blood , vol.93 , pp. 3601-3609
    • Dierlamm, J.1    Baens, M.2    Wlodarska, I.3    Stefanova-Ouzounova, M.4    Hernandez, J.M.5    Hossfeld, D.K.6
  • 6
    • 0003009144 scopus 로고    scopus 로고
    • Molecular biology of lymphomas
    • edited by V.T.J. De Vita, S. Hellman and S.A. Rosenberg. Philadelphia: Lippincott Williams & Wilkins
    • Dalla-Favera, R. and Gaidano, G. (2001) Molecular biology of lymphomas. In Cancer. Principles and Practice of Oncology, edited by V.T.J. De Vita, S. Hellman and S.A. Rosenberg. Pp. 2215-2235. Philadelphia: Lippincott Williams & Wilkins.
    • (2001) Cancer. Principles and Practice of Oncology , pp. 2215-2235
    • Dalla-Favera, R.1    Gaidano, G.2
  • 8
    • 0026053958 scopus 로고
    • "Progression from lymphoid hyperplasia to high grade malignant lymphoma in mice transgenic for the t(14;18)"
    • McDonnel, T.J. and Korsmeyer, S.J. (1991) "Progression from lymphoid hyperplasia to high grade malignant lymphoma in mice transgenic for the t(14;18)", Nature, 349, 254-256.
    • (1991) Nature , vol.349 , pp. 254-256
    • McDonnel, T.J.1    Korsmeyer, S.J.2
  • 10
    • 0035839959 scopus 로고    scopus 로고
    • "Mechanisms of chromosomal translocation in B-cell lymphoma"
    • Küppers, R. and Dalla-Favera, R. (2001) "Mechanisms of chromosomal translocation in B-cell lymphoma", Oncogene, 20, 5580-5594.
    • (2001) Oncogene , vol.20 , pp. 5580-5594
    • Küppers, R.1    Dalla-Favera, R.2
  • 12
    • 1042275303 scopus 로고    scopus 로고
    • "Frequent occurrence of deletions and duplications during somatic hypermutation: Implications for oncogene translocations and heavy chain disease"
    • Goossens, T., Klein, U. and Küppers, R. (1998) "Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease", Proceedings of the National Academy of Sciences of the United States of America, 93, 13979-13984.
    • (1998) Proceedings of the National Academy of Sciences of the United States of America , vol.93 , pp. 13979-13984
    • Goossens, T.1    Klein, U.2    Küppers, R.3
  • 13
    • 0026443954 scopus 로고
    • "Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis"
    • Rogozin, I.B. and Kolchanov, N.A. (1992) "Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis", Biochimica et Biophysica Acta, 1171, 11-18.
    • (1992) Biochimica et Biophysica Acta , vol.1171 , pp. 11-18
    • Rogozin, I.B.1    Kolchanov, N.A.2
  • 14
    • 0034268780 scopus 로고    scopus 로고
    • "Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme"
    • Muramatsu, M., Kinoshita, K., Fagarasan, S., Yamada, S., Shinkai, Y. and Honjo, T. (2000) "Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme", Cell, 102, 553-563.
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 15
    • 0033637358 scopus 로고    scopus 로고
    • "DNA double-strand breaks in immunoglobulin genes undergoing somatic hypermutation"
    • Bross, L., Fukita, Y., McBlane, F., Demolliere, C., Rajewsky, K. and Jacobs, H. (2000) "DNA double-strand breaks in immunoglobulin genes undergoing somatic hypermutation", Immunity, 13, 589-597.
    • (2000) Immunity , vol.13 , pp. 589-597
    • Bross, L.1    Fukita, Y.2    McBlane, F.3    Demolliere, C.4    Rajewsky, K.5    Jacobs, H.6
  • 16
    • 0034626802 scopus 로고    scopus 로고
    • "Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes"
    • Papavasiliou, F.N. and Schatz, D.G. (2000) "Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes", Nature, 408, 216-221.
    • (2000) Nature , vol.408 , pp. 216-221
    • Papavasiliou, F.N.1    Schatz, D.G.2
  • 18
  • 19
    • 2642623612 scopus 로고    scopus 로고
    • "Mutation of BCL-6 gene in normal B-cells by the process of somatic hypermutation of Ig genes
    • Shen, H.M., Peters, A., Baron, B., Zhu, X. and Storb, U. (1998) "Mutation of BCL-6 gene in normal B-cells by the process of somatic hypermutation of Ig genes. Science, 280, 1750-1752.
    • (1998) Science , vol.280 , pp. 1750-1752
    • Shen, H.M.1    Peters, A.2    Baron, B.3    Zhu, X.4    Storb, U.5
  • 20
    • 0034684682 scopus 로고    scopus 로고
    • "Somatic mutation of the CD95 gene in human B-cells as a side-effect of the germinal center reaction"
    • Müschen, M., Re, D., Jungnickel, B., Diehl, V., Rajewsky, K. and Kuppers, R. (2000) "Somatic mutation of the CD95 gene in human B-cells as a side-effect of the germinal center reaction", Journal of Experimental Medicine, 192, 1833-1840.
    • (2000) Journal of Experimental Medicine , vol.192 , pp. 1833-1840
    • Müschen, M.1    Re, D.2    Jungnickel, B.3    Diehl, V.4    Rajewsky, K.5    Kuppers, R.6
  • 21
  • 22
    • 0038243177 scopus 로고    scopus 로고
    • "Mutations of the BCL-6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma"
    • Pasqualucci, L., Migliazza, A., Basso, K., Houldsworth, J., Chaganti, R.S. and Dalla-Favera, R. (2003) "Mutations of the BCL-6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma", Blood, 101, 2914-2923.
    • (2003) Blood , vol.101 , pp. 2914-2923
    • Pasqualucci, L.1    Migliazza, A.2    Basso, K.3    Houldsworth, J.4    Chaganti, R.S.5    Dalla-Favera, R.6
  • 24
    • 0030715354 scopus 로고    scopus 로고
    • "Mutations in the Fas antigen in patients with multiple myeloma"
    • Landowski, T.H., Qu, N., Buyuksal, I., Painter, J.S. and Dalton, W.S. (1997) "Mutations in the Fas antigen in patients with multiple myeloma", Blood, 90, 4266-4270.
    • (1997) Blood , vol.90 , pp. 4266-4270
    • Landowski, T.H.1    Qu, N.2    Buyuksal, I.3    Painter, J.S.4    Dalton, W.S.5
  • 25
    • 0000501561 scopus 로고    scopus 로고
    • "Somatic Fas mutations in non-Hodgkin's lymphoma: Association with extranodal disease and autoimmunity"
    • Gronbaek, K., Straten, P.T., Ralfkiaer, E., Ahrenkiel, V., Andersen, M.K., Hansen, N.E., et al. (1998) "Somatic Fas mutations in non-Hodgkin's lymphoma: association with extranodal disease and autoimmunity", Blood, 92, 3018-3024.
    • (1998) Blood , vol.92 , pp. 3018-3024
    • Gronbaek, K.1    Straten, P.T.2    Ralfkiaer, E.3    Ahrenkiel, V.4    Andersen, M.K.5    Hansen, N.E.6
  • 29
    • 0028064764 scopus 로고
    • "A revised European-American classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group"
    • Harris, N.L., Jaffe, E.S., Stein, H., Banks, P.M., Chan, J.K., Cleary, M.L., et al. (1994) "A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group", Blood, 84, 1361-1392.
    • (1994) Blood , vol.84 , pp. 1361-1392
    • Harris, N.L.1    Jaffe, E.S.2    Stein, H.3    Banks, P.M.4    Chan, J.K.5    Cleary, M.L.6
  • 31
    • 0030052683 scopus 로고    scopus 로고
    • "REL proto-oncogene is frequently amplified in extranodal diffuse large cell lymphoma"
    • Houldsworth, J., Mathew, S., Rao, P.H., Dyomina, K., Louie, D.C., Parsa, N., et al. (1996) "REL proto-oncogene is frequently amplified in extranodal diffuse large cell lymphoma", Blood, 87, 25-29.
    • (1996) Blood , vol.87 , pp. 25-29
    • Houldsworth, J.1    Mathew, S.2    Rao, P.H.3    Dyomina, K.4    Louie, D.C.5    Parsa, N.6
  • 32
    • 0032103404 scopus 로고
    • "Cloning and mapping of human chromosome 6q26-q27 deleted in B-cell non-Hodgkin lymphoma and multiple tumor types"
    • Hauptschein, R.S., Gamberi, B., Rao, P.H., Frigeri, F., Scotto, L., Venkatraj, V.S., et al. (1988) "Cloning and mapping of human chromosome 6q26-q27 deleted in B-cell non-Hodgkin lymphoma and multiple tumor types", Genomics, 50, 170-186.
    • (1988) Genomics , vol.50 , pp. 170-186
    • Hauptschein, R.S.1    Gamberi, B.2    Rao, P.H.3    Frigeri, F.4    Scotto, L.5    Venkatraj, V.S.6
  • 34
    • 0027306091 scopus 로고
    • "LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas"
    • Kerckaert, J.P., Deweindt, C., Tilly, H., Quief, S., Lecocq, G. and Bastard, C. (1993) "LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas", Nature Genetics, 5, 66-70.
    • (1993) Nature Genetics , vol.5 , pp. 66-70
    • Kerckaert, J.P.1    Deweindt, C.2    Tilly, H.3    Quief, S.4    Lecocq, G.5    Bastard, C.6
  • 36
    • 0028031988 scopus 로고
    • "Gene involved in the 3q27 translocation associated with B-cell lymphoma, BCL5, encodes a Kruppel-like zinc-finger protein"
    • Miki, T., Kawamata, N., Hirosawa, S. and Aoki, N. (1994) "Gene involved in the 3q27 translocation associated with B-cell lymphoma, BCL5, encodes a Kruppel-like zinc-finger protein", Blood, 83, 26-32.
    • (1994) Blood , vol.83 , pp. 26-32
    • Miki, T.1    Kawamata, N.2    Hirosawa, S.3    Aoki, N.4
  • 38
    • 0028110129 scopus 로고
    • "The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila"
    • Zollman, S., Godt, D., Prive, G.G., Couderc, J.L. and Laski, F.A. (1994) "The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila", Proceedings of the National Academy of Sciences of the United States of America, 91, 10717-10721.
    • (1994) Proceedings of the National Academy of Sciences of the United States of America , vol.91 , pp. 10717-10721
    • Zollman, S.1    Godt, D.2    Prive, G.G.3    Couderc, J.L.4    Laski, F.A.5
  • 40
    • 0032128002 scopus 로고    scopus 로고
    • "Antigen-receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the Bcl-6 transcription factor"
    • Niu, H., Ye, B.H. and Dalla-Favera, R. (1998) "Antigen-receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the Bcl-6 transcription factor", Genes & Development, 12, 1953-1961.
    • (1998) Genes & Development , vol.12 , pp. 1953-1961
    • Niu, H.1    Ye, B.H.2    Dalla-Favera, R.3
  • 42
    • 0029019660 scopus 로고
    • "Bcl-6 gene product, a 92 to 98-kD nuclear phosphoprotein, is highly expressed in germinal center B-cells and their neoplastic counterparts"
    • Onizuka, T., Moriyama, M., Yamochi, T., Kuroda, T., Kazama, A., Kanazawa, N., et al. (1995) "Bcl-6 gene product, a 92 to 98-kD nuclear phosphoprotein, is highly expressed in germinal center B-cells and their neoplastic counterparts", Blood, 86, 28-37.
    • (1995) Blood , vol.86 , pp. 28-37
    • Onizuka, T.1    Moriyama, M.2    Yamochi, T.3    Kuroda, T.4    Kazama, A.5    Kanazawa, N.6
  • 43
    • 0030006070 scopus 로고    scopus 로고
    • "Clonal selection and learning in the antibody system"
    • Rajewsky, K. (1996) "Clonal selection and learning in the antibody system", Nature, 381, 751-758.
    • (1996) Nature , vol.381 , pp. 751-758
    • Rajewsky, K.1
  • 44
    • 17144439800 scopus 로고    scopus 로고
    • "The Bcl-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation"
    • Ye, B.H., Cattoretti, G., Shen, Q., Zhang, J., Hawe, N., de Waard, R., et al. (1997) "The Bcl-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation", Nature Genetics, 16, 161-170.
    • (1997) Nature Genetics , vol.16 , pp. 161-170
    • Ye, B.H.1    Cattoretti, G.2    Shen, Q.3    Zhang, J.4    Hawe, N.5    de Waard, R.6
  • 45
    • 0033680860 scopus 로고    scopus 로고
    • "Bcl-6 represses genes that function in lymphocyte differentiation, inflammation, and cell-cycle control"
    • Shaffer, A.L., Yu, X., He, Y., Boldrick, J., Chan, E.P. and Staudt, L.M. (2000) "Bcl-6 represses genes that function in lymphocyte differentiation, inflammation, and cell-cycle control", Immunity, 13, 199-212.
    • (2000) Immunity , vol.13 , pp. 199-212
    • Shaffer, A.L.1    Yu, X.2    He, Y.3    Boldrick, J.4    Chan, E.P.5    Staudt, L.M.6
  • 46
    • 0034684672 scopus 로고    scopus 로고
    • "Suppression of signal transducer and activator of transcription 3-dependent B lymphocyte terminal differentiation by Bcl-6"
    • Reljic, R., Wagner, S.D., Peakman, L.J. and Fearon, D.T. (2000) "Suppression of signal transducer and activator of transcription 3-dependent B lymphocyte terminal differentiation by Bcl-6", Journal of Experimental Medicine, 192, 1841-1848.
    • (2000) Journal of Experimental Medicine , vol.192 , pp. 1841-1848
    • Reljic, R.1    Wagner, S.D.2    Peakman, L.J.3    Fearon, D.T.4
  • 48
    • 0042161855 scopus 로고    scopus 로고
    • "BCL6 controls the expression of the B7-1/CD80 co-stimulatory receptor in germinal-center B-cells"
    • Niu, H., Cattoretti, G. and Dalla-Favera, R. (2003) "BCL6 controls the expression of the B7-1/CD80 co-stimulatory receptor in germinal-center B-cells", Journal of Experimental Medicine, 198, 211-221.
    • (2003) Journal of Experimental Medicine , vol.198 , pp. 211-221
    • Niu, H.1    Cattoretti, G.2    Dalla-Favera, R.3
  • 49
    • 0030901289 scopus 로고    scopus 로고
    • "Control of inflammation, cytokine expression, and germinal-center formation by Bcl-6"
    • Dent, A.L., Shaffer, A.L., Yu, X., Allman, D. and Staudt, L.M. (1997) "Control of inflammation, cytokine expression, and germinal-center formation by Bcl-6", Science, 276, S89-S92.
    • (1997) Science , vol.276
    • Dent, A.L.1    Shaffer, A.L.2    Yu, X.3    Allman, D.4    Staudt, L.M.5
  • 50
    • 0032827421 scopus 로고    scopus 로고
    • "Transcriptional repression of Stat6-dependent interleukin-4-induced genes by Bcl-6: Specific regulation of epsilon transcription and immunoglobulin E switching"
    • Harris, M.B., Chang, C.C., Berton, M.T., Danial, N.N., Zhang, J., Kuehner, D., et al. (1999) "Transcriptional repression of Stat6-dependent interleukin-4-induced genes by Bcl-6: specific regulation of epsilon transcription and immunoglobulin E switching", Molecular and Cellular Biology, 19, 7264-7275.
    • (1999) Molecular and Cellular Biology , vol.19 , pp. 7264-7275
    • Harris, M.B.1    Chang, C.C.2    Berton, M.T.3    Danial, N.N.4    Zhang, J.5    Kuehner, D.6
  • 51
    • 0029562068 scopus 로고
    • "Chromosomal translocations cause deregulated Bcl6 expression by promoter substitution in B-cell lymphoma"
    • Ye, B.H., Chaganti, S., Chang, C.C., Niu, H., Corradini, P., Chaganti, R.S. and Dalla-Favera, R. (1995) "Chromosomal translocations cause deregulated Bcl6 expression by promoter substitution in B-cell lymphoma", EMBO Journal, 14, 6209-6217.
    • (1995) EMBO Journal , vol.14 , pp. 6209-6217
    • Ye, B.H.1    Chaganti, S.2    Chang, C.C.3    Niu, H.4    Corradini, P.5    Chaganti, R.S.6    Dalla-Favera, R.7
  • 53
    • 0036898253 scopus 로고    scopus 로고
    • "Acetylation inactivates the transcriptional repressor Bcl-6"
    • Bereshchenko, O.R., Gu, W. and Dalla-Favera, R. (2002) "Acetylation inactivates the transcriptional repressor Bcl-6", Nature Genetics, 32, 606-613.
    • (2002) Nature Genetics , vol.32 , pp. 606-613
    • Bereshchenko, O.R.1    Gu, W.2    Dalla-Favera, R.3
  • 55
    • 0035694469 scopus 로고    scopus 로고
    • "Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases"
    • Barlev, N.A., Liu, L., Chehab, N.H., Mansfield, K., Harris, K.G., Halazonetis, T.D. and Berger, S.L. (2001) "Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases", Molecular Cell, 8, 1243-1254.
    • (2001) Molecular Cell , vol.8 , pp. 1243-1254
    • Barlev, N.A.1    Liu, L.2    Chehab, N.H.3    Mansfield, K.4    Harris, K.G.5    Halazonetis, T.D.6    Berger, S.L.7
  • 56
    • 0030797585 scopus 로고    scopus 로고
    • "Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain"
    • Gu, W. and Roeder, R.G. (1997) "Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain", Cell, 90, 595-606.
    • (1997) Cell , vol.90 , pp. 595-606
    • Gu, W.1    Roeder, R.G.2
  • 57
    • 0034045040 scopus 로고    scopus 로고
    • "Histone deacetylases, transcriptional control, and cancer"
    • Cress, W.D. and Seto, E. (2000) "Histone deacetylases, transcriptional control, and cancer", Journal of Cellular Physiology, 184, 1-16.
    • (2000) Journal of Cellular Physiology , vol.184 , pp. 1-16
    • Cress, W.D.1    Seto, E.2
  • 58
    • 0034677535 scopus 로고    scopus 로고
    • "Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase"
    • Imai, S., Armstrong, C.M., Kaeberlein, M. and Guarente, L. (2000) "Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase". Nature, 403, 795-800.
    • (2000) Nature , vol.403 , pp. 795-800
    • Imai, S.1    Armstrong, C.M.2    Kaeberlein, M.3    Guarente, L.4
  • 60
    • 0035913911 scopus 로고    scopus 로고
    • "Negative control of p53 by Sir2alpha promotes cell survival under stress"
    • Luo, J., Nikolaev, A.Y., Imai, S., Chen, D., Su, F., Shiloh, A., et al. (2001) "Negative control of p53 by Sir2alpha promotes cell survival under stress", Cell, 107, 137-148.
    • (2001) Cell , vol.107 , pp. 137-148
    • Luo, J.1    Nikolaev, A.Y.2    Imai, S.3    Chen, D.4    Su, F.5    Shiloh, A.6
  • 61
    • 0034676439 scopus 로고    scopus 로고
    • "Deacetylation of p53 modulates its effect on cell growth and apoptosis"
    • Luo, J., Su, F., Chen, D., Shiloh, A. and Gu, W. (2000) "Deacetylation of p53 modulates its effect on cell growth and apoptosis", Nature, 408, 377-381.
    • (2000) Nature , vol.408 , pp. 377-381
    • Luo, J.1    Su, F.2    Chen, D.3    Shiloh, A.4    Gu, W.5
  • 63
    • 0034596309 scopus 로고    scopus 로고
    • "Histone deacetylase inhibitors: Inducers of differentiation or apoptosis of transformed cells"
    • Marks, P.A., Richon, V.M. and Rifkind, R.A. (2000) "Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells", Journal of the National Cancer Institute, 92, 1210-1216.
    • (2000) Journal of the National Cancer Institute , vol.92 , pp. 1210-1216
    • Marks, P.A.1    Richon, V.M.2    Rifkind, R.A.3
  • 64
    • 0032901751 scopus 로고    scopus 로고
    • "Disrupted p53 function as predictor of treatment failure and poor prognosis in B- and T-cell non-Hodgkin's lymphoma"
    • Moller, M.B., Gerdes, A.M., Skjodt, K., Mortensen, L.S. and Pedersen, N.T. (1999) "Disrupted p53 function as predictor of treatment failure and poor prognosis in B- and T-cell non-Hodgkin's lymphoma", Clinical Cancer Research, 5, 1085-1091.
    • (1999) Clinical Cancer Research , vol.5 , pp. 1085-1091
    • Moller, M.B.1    Gerdes, A.M.2    Skjodt, K.3    Mortensen, L.S.4    Pedersen, N.T.5
  • 66
    • 0025224576 scopus 로고
    • "Nucleosomes: Regulators of transcription"
    • Grunstein, M. (1990) "Nucleosomes: regulators of transcription", Trends in Genetics, 6, 395-400.
    • (1990) Trends in Genetics , vol.6 , pp. 395-400
    • Grunstein, M.1
  • 67
    • 0030722744 scopus 로고    scopus 로고
    • "Association of the origin recognition complex with heterochromatin and HP1 in higher eukaryotes"
    • Pak, D.T., Pflumm, M., Chesnokov, I., Huang, D.W., Kellum, R., Marr, J., et al. (1997) "Association of the origin recognition complex with heterochromatin and HP1 in higher eukaryotes", Cell, 91, 311-323.
    • (1997) Cell , vol.91 , pp. 311-323
    • Pak, D.T.1    Pflumm, M.2    Chesnokov, I.3    Huang, D.W.4    Kellum, R.5    Marr, J.6


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