Frequent mutations of Fas gene in thyroid lymphoma

Cancer Research

Volumn 61, Issue 4, 2001, Pages 1382-1385

  Takakuwa, Tetsuya ^a   Dong, Zhiming ^a   Takayama, Hitoshi ^a   Matsuzuka, Fumio ^b   Nagata, Shigekazu ^a   Aozasa, Katsuyuki ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b KUMA HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; COMPLEMENTARY DNA; FAS ANTIGEN; GENE PRODUCT;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CELL DEATH; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOPLASM; FEMALE; FRAMESHIFT MUTATION; GENE INSERTION; GENE MUTATION; HUMAN; HUMAN TISSUE; LYMPHOMA; MALE; MISSENSE MUTATION; MUTATIONAL ANALYSIS; NONSENSE MUTATION; OPEN READING FRAME; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THYROID CANCER;

AGED; AGED, 80 AND OVER; ANTIGENS, CD95; FEMALE; FRAMESHIFT MUTATION; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHOMA, NON-HODGKIN; MALE; MIDDLE AGED; POINT MUTATION; THYROID NEOPLASMS;

EID: 0035866342     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
2. The Fas death factor
3. Apoptosis by death factor
4. A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen
5. Expansion or elimination of B cells in vivo: Dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor
6. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
7. Missense mutations in the Fas gene resulting in autoimmune lymphoproliferative syndrome: A molecular and immunological analysis
8. Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity
9. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
10. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity
11. Clinical, immunologic, and genetic features of an autoimmune lymphoproliferative syndrome associated with abnormal lymphocyte apoptosis
12. The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutations
13. Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia
14. Tumor B cells from non-Hodgkin's lymphoma are resistant to CD95 (Fas/Apo-1)-mediated apoptosis
15. Sensitivity to Fas-mediated apoptosis is null or weak in B-cell non-Hodgkin's lymphomas and is moderately increased by CD40 ligation
16. Somatic Fas mutations in non-Hodgkin's lymphoma: Association with extranodal disease and autoimmunity
17. Lack of Fas and Fas-L mutations in patients with lymphoproliferative disorders associated with Sjören syndrome and type Il mixed cryoglobulinemia
18. Occurrence and prognosis of extranodal lymphomas
19. Non-Hodgkin's lymphomas in Osaka, Japan
20. Thyroiditis: Current views of pathogenesis
21. Cancer risks in patients with chronic lymphocytic thyroiditis
22. Chronic thyroiditis as a risk factor of B-cell lymphoma in the thyroid gland
23. Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis
24. Microsatellite instability and k-ras, p53 mutations in thyroid lymphoma
25. A revised European-American classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group
26. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis
27. Mutations in the Fas antigen in patients with multiple myeloma
28. Fas gene mutation in the progression of adult T cell leukemia
29. Mutation of CD95 (Fas/Apo-1) gene in adult T-cell leukemia cells
30. Human autoimmune lymphoproliferative syndrome, a defect in the apoptosis-inducing Fas receptor: A lesson from the mouse model
31. Lack of CD95/FAS gene somatic mutations in extranodal, nodal and splenic marginal zone B cell lymphomas
32. Search for rearrangements and/or allelic loss of the Fas/APO-1 gene in 101 human lymphomas
33. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
34. Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumors
35. Fas/Apo-1 (CD95) receptor lacking the intracytoplasmic signaling domain protects tumor cells from Fas-mediated apoptosis
36. NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain
37. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
38. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
39. A novel protein that interacts with the death domain of Fas/APO-1 contains a sequence motif related to the death domain
40. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
41. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors