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Volumn 28, Issue 12, 2003, Pages 1189-1210

Antibody-targeted HPMA copolymer-bound anthracycline antibiotics

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE ANTIBIOTIC AGENT; ANTIBODY; CD71 ANTIBODY; DAUNORUBICIN; DOXORUBICIN; GLYCOPROTEIN P; IMMUNOGLOBULIN; MONOCLONAL ANTIBODY B.72.3; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER; UNCLASSIFIED DRUG;

EID: 1042269568     PISSN: 03778282     EISSN: None     Source Type: Journal    
DOI: 10.1358/dof.2003.028.12.857390     Document Type: Review
Times cited : (18)

References (145)
  • 1
    • 0021270540 scopus 로고
    • The potential use of immunotoxins in transplantation, cancer therapy, and immunoregulation
    • Vitetta, E.S., Uhr, J.W. The potential use of immunotoxins in transplantation, cancer therapy, and immunoregulation. Transplantation 1984, 37: 535-48.
    • (1984) Transplantation , vol.37 , pp. 535-548
    • Vitetta, E.S.1    Uhr, J.W.2
  • 2
    • 0027156735 scopus 로고
    • Immunotoxins: Magic bullets or misquided missiles?
    • Vitetta, E.S., Thorpe, P.E., Uhr, J.W. Immunotoxins: Magic bullets or misquided missiles? Immunol Today 1993, 14: 252-64.
    • (1993) Immunol Today , vol.14 , pp. 252-264
    • Vitetta, E.S.1    Thorpe, P.E.2    Uhr, J.W.3
  • 3
    • 0030913690 scopus 로고    scopus 로고
    • Abnormal differentiation of thymocytes induced by free cyclosporine is avoided when cyclosporine bound to N-(2-hydroxypropyl)methacrylamide copolymer carrier is used
    • Št'astný, M., Ulbrich, K., Strohalm, J., Rossmann, P., Říhová, B. Abnormal differentiation of thymocytes induced by free cyclosporine is avoided when cyclosporine bound to N-(2-hydroxypropyl)methacrylamide copolymer carrier is used. Transplantation 1997, 63: 1818-27.
    • (1997) Transplantation , vol.63 , pp. 1818-1827
    • Št'astný, M.1    Ulbrich, K.2    Strohalm, J.3    Rossmann, P.4    Říhová, B.5
  • 4
    • 0030634591 scopus 로고    scopus 로고
    • Morphology of rat kidney and thymus after native and antibody-coupled cyclosporin A application (reduced toxicity of targeted drug)
    • Rossmann, P., Říhová, B., Strohalm, J., Ulbrich, K. Morphology of rat kidney and thymus after native and antibody-coupled cyclosporin A application (reduced toxicity of targeted drug). Folia Microbiol 1997, 42: 277-87.
    • (1997) Folia Microbiol , vol.42 , pp. 277-287
    • Rossmann, P.1    Říhová, B.2    Strohalm, J.3    Ulbrich, K.4
  • 5
    • 0020004910 scopus 로고
    • Immunotoxins: Hybrid molecules combining high specificity and potent cytotoxicity
    • Jansen, F.K., Blythman, H.E., Cariére, D. et al. Immunotoxins: Hybrid molecules combining high specificity and potent cytotoxicity. Immunol Rev 1982, 62: 185-216.
    • (1982) Immunol Rev , vol.62 , pp. 185-216
    • Jansen, F.K.1    Blythman, H.E.2    Cariére, D.3
  • 6
    • 0020004914 scopus 로고
    • In vitro and in vivo efficacy of conjugates of daunomycin with anti-tumor antibodies
    • Arnon, R., Sela, M. In vitro and in vivo efficacy of conjugates of daunomycin with anti-tumor antibodies. Immunol Rev 1982, 62: 5-27.
    • (1982) Immunol Rev , vol.62 , pp. 5-27
    • Arnon, R.1    Sela, M.2
  • 7
    • 0020004915 scopus 로고
    • Antibody mediated delivery of toxic molecules to antigen bearing target cells
    • Raso, V. Antibody mediated delivery of toxic molecules to antigen bearing target cells. Immunol Rev 1982, 62: 93-117.
    • (1982) Immunol Rev , vol.62 , pp. 93-117
    • Raso, V.1
  • 8
    • 0020004916 scopus 로고
    • Monoclonal antibody-ricin or ricin A chain hybrids: Kinetic analysis of cell killing for tumor therapy
    • Neville, D.M., Youle, R.J. Monoclonal antibody-ricin or ricin A chain hybrids: Kinetic analysis of cell killing for tumor therapy. Immunol Rev 1982, 62: 75-91.
    • (1982) Immunol Rev , vol.62 , pp. 75-91
    • Neville, D.M.1    Youle, R.J.2
  • 9
    • 0020004912 scopus 로고
    • Neoplastic B cells as targets for antibody-ricin A chain immunotoxins
    • Vitetta, E.S., Krolick, K.A., Uhr, J.W. Neoplastic B cells as targets for antibody-ricin A chain immunotoxins. Immunol Rev 1982, 62, 159-83.
    • (1982) Immunol Rev , vol.62 , pp. 159-183
    • Vitetta, E.S.1    Krolick, K.A.2    Uhr, J.W.3
  • 10
    • 0028096216 scopus 로고
    • Retention of B-cell specific monoclonal antibodies by human lymphoma cells
    • Press, O.W., Howell-Clark, S., Anderson, I., Bernstein, I. Retention of B-cell specific monoclonal antibodies by human lymphoma cells. Blood 1994, 83: 1390-7.
    • (1994) Blood , vol.83 , pp. 1390-1397
    • Press, O.W.1    Howell-Clark, S.2    Anderson, I.3    Bernstein, I.4
  • 12
    • 0021354472 scopus 로고
    • Controlled degradability of polymers - A key to drug delivery systems
    • Kopeček, J. Controlled degradability of polymers - A key to drug delivery systems. Biomaterials 1984, 5: 19-25.
    • (1984) Biomaterials , vol.5 , pp. 19-25
    • Kopeček, J.1
  • 13
    • 0025099302 scopus 로고
    • The potential of water-soluble polymeric carriers in targeted and site-specific drug delivery
    • Kopeček, J. The potential of water-soluble polymeric carriers in targeted and site-specific drug delivery. J Control Release 1990, 11: 279-90.
    • (1990) J Control Release , vol.11 , pp. 279-290
    • Kopeček, J.1
  • 14
    • 0041181628 scopus 로고    scopus 로고
    • HPMA copolymer-anticancer drug conjugates: Design, activity, and mechanism of action
    • Kopeček, J., Kopečková, P., Minko, T., Lu, Z.R. HPMA copolymer-anticancer drug conjugates: Design, activity, and mechanism of action. Eur J Pharmaceut Biopharm 2000, 50: 61-81.
    • (2000) Eur J Pharmaceut Biopharm , vol.50 , pp. 61-81
    • Kopeček, J.1    Kopečková, P.2    Minko, T.3    Lu, Z.R.4
  • 16
    • 0022379009 scopus 로고
    • Biological properties of targetable poly[N-(2-hydroxypropyl) methacrylamide]-antibody conjugates
    • Říhová, B., Kopeček, J. Biological properties of targetable poly[N-(2-hydroxypropyl) methacrylamide]-antibody conjugates. J Control Release 1985, 2: 289-310.
    • (1985) J Control Release , vol.2 , pp. 289-310
    • Říhová, B.1    Kopeček, J.2
  • 18
    • 0023930539 scopus 로고
    • Antibody-directed affinity therapy applied to the immune system: In vivo effectiveness and limited toxicity of daunomycin conjugated to HPMA copolymers and targeting antibody
    • Říhová, B., Kopečková, P., Strohalm, J., Rossmann, P., Vetvička, V., Kopeček, J. Antibody-directed affinity therapy applied to the immune system: In vivo effectiveness and limited toxicity of daunomycin conjugated to HPMA copolymers and targeting antibody. Clin Immunol Immunopathol 1988, 46: 100-14.
    • (1988) Clin Immunol Immunopathol , vol.46 , pp. 100-114
    • Říhová, B.1    Kopečková, P.2    Strohalm, J.3    Rossmann, P.4    Vetvička, V.5    Kopeček, J.6
  • 21
    • 0029451952 scopus 로고
    • Antibody-targeted polymer-bound drugs
    • Říhová, B. Antibody-targeted polymer-bound drugs. Folia Microbiol 1995, 40: 367-84.
    • (1995) Folia Microbiol , vol.40 , pp. 367-384
    • Říhová, B.1
  • 22
    • 0029893387 scopus 로고    scopus 로고
    • Cytotoxic and cytostatic effects of anti-Thy 1.2 targeted doxorubicin and cyclosporin A
    • Říhová, B., Strohalm, J., Plocová, D. et al. Cytotoxic and cytostatic effects of anti-Thy 1.2 targeted doxorubicin and cyclosporin A. J Control Release 1996, 40: 303-19.
    • (1996) J Control Release , vol.40 , pp. 303-319
    • Říhová, B.1    Strohalm, J.2    Plocová, D.3
  • 23
    • 0033795003 scopus 로고    scopus 로고
    • The anti-proliferative effect of a lectin- and anti-Thy-1.2 antibody-targeted HPMA copolymer-bound doxorubicin on primary and metastatic human colorectal carcinoma and on human colorectal carcinoma transfected with mouse Thy-1.2 gene
    • Říhová, B., Jelínková, M., Strohalm, J. et al. The anti-proliferative effect of a lectin- and anti-Thy-1.2 antibody-targeted HPMA copolymer-bound doxorubicin on primary and metastatic human colorectal carcinoma and on human colorectal carcinoma transfected with mouse Thy-1.2 gene. Bioconj Chem 2000, 11: 664-73.
    • (2000) Bioconj Chem , vol.11 , pp. 664-673
    • Říhová, B.1    Jelínková, M.2    Strohalm, J.3
  • 25
    • 0037122737 scopus 로고    scopus 로고
    • Acquired and specific immunological mechanisms co-responsible for efficacy of polymer-bound drugs
    • Říhová, B., Strohalm, J., Kubáč ková, K. et al. Acquired and specific immunological mechanisms co-responsible for efficacy of polymer-bound drugs. J Control Release 2002, 78: 97-114.
    • (2002) J Control Release , vol.78 , pp. 97-114
    • Říhová, B.1    Strohalm, J.2    Kubáčková, K.3
  • 26
    • 0037072569 scopus 로고    scopus 로고
    • Immunomodulating activities of soluble synthetic polymer-bound drugs
    • Říhová, B. Immunomodulating activities of soluble synthetic polymer-bound drugs. Adv Drug Del Rev 2002, 54: 653-74.
    • (2002) Adv Drug Del Rev , vol.54 , pp. 653-674
    • Říhová, B.1
  • 27
    • 17144464252 scopus 로고    scopus 로고
    • Drug-HPMA-Hulg conjugates effective against human solid cancer
    • Maeda et al. (Eds.). Kluwer Academic/Plenum Publishers: New York
    • Říhová, B., Strohalm, J., Kubáč ková, K. et al. Drug-HPMA-Hulg conjugates effective against human solid cancer. In: Polymer Drugs in the Clinical Stage. Maeda et al. (Eds.). Kluwer Academic/Plenum Publishers: New York 2003, 125-43.
    • (2003) Polymer Drugs in the Clinical Stage , pp. 125-143
    • Říhová, B.1    Strohalm, J.2    Kubáčková, K.3
  • 28
    • 0141548120 scopus 로고    scopus 로고
    • Cytostatic and immunomobilizing activities of polymer-bound drugs; experimental and first clinical data
    • Říhová, B., Strohalm, J., Prausová, J. et al. Cytostatic and immunomobilizing activities of polymer-bound drugs; experimental and first clinical data. J Control Release 2003, 91: 1-16.
    • (2003) J Control Release , vol.91 , pp. 1-16
    • Říhová, B.1    Strohalm, J.2    Prausová, J.3
  • 29
    • 0141615972 scopus 로고    scopus 로고
    • Clinical implications of N-(2-hydroxypropyl)methacrylamide copolymers
    • Říhová, B., Kubáčková, K. Clinical implications of N-(2-hydroxypropyl)methacrylamide copolymers. Curr Pharmaceut Biotechnol 2003, 4: 311-22.
    • (2003) Curr Pharmaceut Biotechnol , vol.4 , pp. 311-322
    • Říhová, B.1    Kubáčková, K.2
  • 30
    • 0024439808 scopus 로고
    • Evaluation of protein-N-(2-hydroxypropyl)methacrylamide copolymer conjugates as targetable drug carriers. 1. Binding, pinocytic uptake and intracellular distribution of transferrin and antitransferrin receptor antibody conjugates
    • Flanagan, P.A., Kopečková, P., Kopeček, J., Duncan, R. Evaluation of protein-N-(2-hydroxypropyl)methacrylamide copolymer conjugates as targetable drug carriers. 1. Binding, pinocytic uptake and intracellular distribution of transferrin and antitransferrin receptor antibody conjugates. Biochim Biophys Acta 1989, 993: 83-91.
    • (1989) Biochim Biophys Acta , vol.993 , pp. 83-91
    • Flanagan, P.A.1    Kopečková, P.2    Kopeček, J.3    Duncan, R.4
  • 31
    • 0025283251 scopus 로고
    • Immunogenicity of protein-N-(2-hydroxypropyl)methacrylamide copolymer conjugates in A/J and B10 mice
    • Flanagan, P.A., Duncan, R., Říhová, B., Šubr, V., Kopeček, J. Immunogenicity of protein-N-(2-hydroxypropyl)methacrylamide copolymer conjugates in A/J and B10 mice. J Bioact Comp Polym 1990, 5: 151-66.
    • (1990) J Bioact Comp Polym , vol.5 , pp. 151-166
    • Flanagan, P.A.1    Duncan, R.2    Říhová, B.3    Šubr, V.4    Kopeček, J.5
  • 32
    • 0030560836 scopus 로고    scopus 로고
    • Comparison of the binding kinetics of antibody-targeted N-(2-hydroxypropyl)methacrylamide (HPMA)-bound doxorubicin in vitro and in vivo
    • Št'astný, M., Říhová, B., Strohalm, J., Ulbrich, K. Comparison of the binding kinetics of antibody-targeted N-(2-hydroxypropyl)methacrylamide (HPMA)-bound doxorubicin in vitro and in vivo. J Control Release 1996, 42: 229-36.
    • (1996) J Control Release , vol.42 , pp. 229-236
    • Št'astný, M.1    Říhová, B.2    Strohalm, J.3    Ulbrich, K.4
  • 33
    • 0033105569 scopus 로고    scopus 로고
    • A possibility to overcome P-glycoprotein (PGP)-mediated multidrug resistance by an tibody-targeted drugs conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer carrier
    • Št'astný, M., Strohalm, J., Plocová, D., Ulbrich, K., Říhová, B. A possibility to overcome P-glycoprotein (PGP)-mediated multidrug resistance by an tibody-targeted drugs conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer carrier. Eur J Cancer 1999, 35: 459-66.
    • (1999) Eur J Cancer , vol.35 , pp. 459-466
    • Št'astný, M.1    Strohalm, J.2    Plocová, D.3    Ulbrich, K.4    Říhová, B.5
  • 35
    • 0032498552 scopus 로고    scopus 로고
    • HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. II. Processing in epithelial ovarian carcinoma cells in vitro
    • Omelyanenko, V., Gentry, C., Kopečková, P., Kopeček, J. HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. II. Processing in epithelial ovarian carcinoma cells in vitro. Intl J Cancer 1998, 75: 600-8.
    • (1998) Intl J Cancer , vol.75 , pp. 600-608
    • Omelyanenko, V.1    Gentry, C.2    Kopečková, P.3    Kopeček, J.4
  • 36
    • 0032580444 scopus 로고    scopus 로고
    • Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fate
    • Omelyanenko, V., Kopečková, P., Gentry, C., Kopeček, J. Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fate. J Control Release 1998, 53: 25-37.
    • (1998) J Control Release , vol.53 , pp. 25-37
    • Omelyanenko, V.1    Kopečková, P.2    Gentry, C.3    Kopeček, J.4
  • 37
    • 0036119335 scopus 로고    scopus 로고
    • In vitro and in vivo effect of HPMA copolymer-bound doxorubicin targeted to transferrin receptor of B-cell lymphoma 38C13
    • Kovář, M., Strohalm, J., Ulbrich, K., Ří hová, B. In vitro and in vivo effect of HPMA copolymer-bound doxorubicin targeted to transferrin receptor of B-cell lymphoma 38C13. J Drug Targ 2002, 10: 23-30.
    • (2002) J Drug Targ , vol.10 , pp. 23-30
    • Kovář, M.1    Strohalm, J.2    Ulbrich, K.3    Říhová, B.4
  • 38
    • 0036009640 scopus 로고    scopus 로고
    • Star structure of antibody-targeted HPMA copolymer-bound doxorubicin: A novel type of polymeric conjugate for targeted drug delivery with potent antitumor effect
    • Kovář, M., Strohalm, J., Etrych, T., Ulbrich, K., Říhová, B. Star structure of antibody-targeted HPMA copolymer-bound doxorubicin: A novel type of polymeric conjugate for targeted drug delivery with potent antitumor effect. Bioconj Chem 2002, 13: 206-15.
    • (2002) Bioconj Chem , vol.13 , pp. 206-215
    • Kovář, M.1    Strohalm, J.2    Etrych, T.3    Ulbrich, K.4    Říhová, B.5
  • 40
    • 0020682412 scopus 로고
    • Targeting of N-(2-hydroxypro-pyl)methacrylamide copolymers to liver by incorporation of galactose residues
    • Duncan, R., Kopeček, J., Rejmanová, P., Lloyd, J.B. Targeting of N-(2-hydroxypro-pyl)methacrylamide copolymers to liver by incorporation of galactose residues. Biochim Biophys Acta 1983, 755: 518-21.
    • (1983) Biochim Biophys Acta , vol.755 , pp. 518-521
    • Duncan, R.1    Kopeček, J.2    Rejmanová, P.3    Lloyd, J.B.4
  • 42
    • 0022635574 scopus 로고
    • Fate of N-(2-hydroxypropyl)methacrylamide copolymers with pendent galactosamine residues after intravenous administration to rats
    • Duncan, R., Seymour, L.C.W., Scarlett, L., Lloyd, J.B., Rejmanová, P., Kopeček, J. Fate of N-(2-hydroxypropyl)methacrylamide copolymers with pendent galactosamine residues after intravenous administration to rats. Biochim Biophys Acta 1986, 880: 62-71.
    • (1986) Biochim Biophys Acta , vol.880 , pp. 62-71
    • Duncan, R.1    Seymour, L.C.W.2    Scarlett, L.3    Lloyd, J.B.4    Rejmanová, P.5    Kopeček, J.6
  • 43
    • 0023141221 scopus 로고
    • Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. 1. Evaluation of daunomycin and puromycin conjugates in vitro
    • Duncan, R., Kopeckova-Rejmanova, P., Strohalm, J. et al. Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. 1. Evaluation of daunomycin and puromycin conjugates in vitro. Br J Cancer 1987, 55: 165-74.
    • (1987) Br J Cancer , vol.55 , pp. 165-174
    • Duncan, R.1    Kopeckova-Rejmanova, P.2    Strohalm, J.3
  • 44
    • 0023829660 scopus 로고
    • Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. II. Evaluation of daunomycin conjugates in vivo against L1210 leukaemia
    • Duncan, R., Kopečková, P., Strohalm, J., Hume, I.C., Lloyd, J.B., Kopeček, J. Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. II. Evaluation of daunomycin conjugates in vivo against L1210 leukaemia. Br J Cancer 1988, 57: 147-56.
    • (1988) Br J Cancer , vol.57 , pp. 147-156
    • Duncan, R.1    Kopečková, P.2    Strohalm, J.3    Hume, I.C.4    Lloyd, J.B.5    Kopeček, J.6
  • 45
    • 0025856232 scopus 로고
    • Macromolecular prodrugs for use in targeted cancer chemotherapy: Melphalan covalently coupled to N-(2-hydroxypropyl)methacrylamide copolymers
    • Duncan, R., Hume, I.C., Yardley, H.J., Flanagan, P.A., Ulbrich, K., Šubr, V., Strohalm, J. Macromolecular prodrugs for use in targeted cancer chemotherapy: Melphalan covalently coupled to N-(2-hydroxypropyl)methacrylamide copolymers. J Control Release 1991, 16: 121-36.
    • (1991) J Control Release , vol.16 , pp. 121-136
    • Duncan, R.1    Hume, I.C.2    Yardley, H.J.3    Flanagan, P.A.4    Ulbrich, K.5    Šubr, V.6    Strohalm, J.7
  • 46
    • 0027253329 scopus 로고
    • 6 toward human hepatocarcinoma cell fine (PLC/PRF/5) targeted with galactosamine and to mouse splenocytes targeted with anti-Thy 1.2 antibodies
    • 6 toward human hepatocarcinoma cell fine (PLC/PRF/5) targeted with galactosamine and to mouse splenocytes targeted with anti-Thy 1.2 antibodies. J Control Release 1993, 25: 71-87.
    • (1993) J Control Release , vol.25 , pp. 71-87
    • Říhová, B.1    Krinick, N.L.2    Kopeček, J.3
  • 48
    • 0001319102 scopus 로고
    • N-(2-Hydroxypropyl)methacrylamide copolymers containing pendant saccharide moieties. Synthesis and bioadhesive properties
    • Rathi, R.C., Kopečková, P., Říhová, B., Kopeček, J. N-(2-Hydroxypropyl)methacrylamide copolymers containing pendant saccharide moieties. Synthesis and bioadhesive properties. J Polym Sci Part A: Polym Chem 1991, 29: 1895-902.
    • (1991) J Polym Sci Part A: Polym Chem , vol.29 , pp. 1895-1902
    • Rathi, R.C.1    Kopečková, P.2    Říhová, B.3    Kopeček, J.4
  • 49
    • 0343953064 scopus 로고    scopus 로고
    • Biorecognition of HPMA copolymer-lectin conjugates as an indicator of differentiation of cell-surface glycoproteins in development, maturation and diseases of human, and rodent gastrointestinal tissues
    • Wroblewski, S., Berenson, M., Kopečková, P., Kopeček, J. Biorecognition of HPMA copolymer-lectin conjugates as an indicator of differentiation of cell-surface glycoproteins in development, maturation and diseases of human, and rodent gastrointestinal tissues. J Biomed Mater Res 2000, 329-42.
    • (2000) J Biomed Mater Res , pp. 329-342
    • Wroblewski, S.1    Berenson, M.2    Kopečková, P.3    Kopeček, J.4
  • 51
    • 0027130079 scopus 로고
    • Polymeric drug-carriers containing doxorubicin and melanocyte-stimulating hormone: In vitro and in vivo evaluation against murine melanoma
    • O'Hare, K.B., Duncan, R., Strohalm, J., Ulbrich, K., Kopeč ková, P. Polymeric drug-carriers containing doxorubicin and melanocyte-stimulating hormone: In vitro and in vivo evaluation against murine melanoma. J Drug Targ 1993, 1: 217-29.
    • (1993) J Drug Targ , vol.1 , pp. 217-229
    • O'Hare, K.B.1    Duncan, R.2    Strohalm, J.3    Ulbrich, K.4    Kopečková, P.5
  • 52
    • 0032772050 scopus 로고    scopus 로고
    • Biorecognition of HPMA copolymer-adriamycin conjugates by lymphocytes mediated by synthetic receptor binding epitopes
    • Omelyanenko, V., Kopečková, P., Prakash, R., Ebert, Ch. D., Kopeček, J. Biorecognition of HPMA copolymer-adriamycin conjugates by lymphocytes mediated by synthetic receptor binding epitopes. Pharm Res 1999, 16: 1010-9.
    • (1999) Pharm Res , vol.16 , pp. 1010-1019
    • Omelyanenko, V.1    Kopečková, P.2    Prakash, R.3    Ebert, Ch.D.4    Kopeček, J.5
  • 54
    • 0022002504 scopus 로고
    • Stability in rat plasma and serum of lysosomally degradable oligopeptide sequences in N-(2-hydroxypropyl)methacrylamide copolymers
    • Rejmanová, P., Kopeček, J., Duncan, R., Lloyd, J.B. Stability in rat plasma and serum of lysosomally degradable oligopeptide sequences in N-(2-hydroxypropyl)methacrylamide copolymers. Biomaterials 1985, 6: 45-8.
    • (1985) Biomaterials , vol.6 , pp. 45-48
    • Rejmanová, P.1    Kopeček, J.2    Duncan, R.3    Lloyd, J.B.4
  • 55
    • 0020467066 scopus 로고
    • Degradation of side-chains of N-(2-hydroxypropyl)methacrylamide copolymers by lysosomal thiol-proteinases
    • Duncan, R., Cable, H.C., Lloyd, J.B., Rejmanová, P., Kopeček, J. Degradation of side-chains of N-(2-hydroxypropyl)methacrylamide copolymers by lysosomal thiol-proteinases. Biosci Rep 1982, 2: 1041-6.
    • (1982) Biosci Rep , vol.2 , pp. 1041-1046
    • Duncan, R.1    Cable, H.C.2    Lloyd, J.B.3    Rejmanová, P.4    Kopeček, J.5
  • 56
    • 0004165562 scopus 로고    scopus 로고
    • Delves, P.J. and Roitt, I.M. (Eds.). Academic Press
    • Encyclopedia of Immunology, 2nd Ed. Delves, P.J. and Roitt, I.M. (Eds.). Academic Press 1998.
    • (1998) Encyclopedia of Immunology, 2nd Ed.
  • 57
    • 0020523633 scopus 로고
    • Immunogenicity of N-(2-hydroxypropyl)methacrylamide copolymers - Potential hapten or drug carriers
    • Říhová, B., Ulbrich, K., Kopeček, J., Mančal, P. Immunogenicity of N-(2-hydroxypropyl)methacrylamide copolymers - Potential hapten or drug carriers. Folia Microbiol 1983, 28: 217-27.
    • (1983) Folia Microbiol , vol.28 , pp. 217-227
    • Říhová, B.1    Ulbrich, K.2    Kopeček, J.3    Mančal, P.4
  • 58
    • 0021274948 scopus 로고
    • Effect of the chemical structure of N-(2-hydroxypropyl)methacrylamide copolymers on their ability to induce antibody formation in inbred strains of mice
    • Říhová, B., Kopeček, J., Ulbrich, K., Pospíšil, J., Mančal, P. Effect of the chemical structure of N-(2-hydroxypropyl)methacrylamide copolymers on their ability to induce antibody formation in inbred strains of mice. Biomaterials 1984, 5: 143-8.
    • (1984) Biomaterials , vol.5 , pp. 143-148
    • Říhová, B.1    Kopeček, J.2    Ulbrich, K.3    Pospíšil, J.4    Mančal, P.5
  • 60
    • 0022952658 scopus 로고
    • The activity of complement in the presence of N-(2-hydroxypropyl)methacrylamide copolymers
    • Šimečková, J., Říhová, B., Plocová, D., Kopeček, J. The activity of complement in the presence of N-(2-hydroxypropyl)methacrylamide copolymers. J Bioact Comp Polym 1986, 1: 20-31.
    • (1986) J Bioact Comp Polym , vol.1 , pp. 20-31
    • Šimečková, J.1    Říhová, B.2    Plocová, D.3    Kopeček, J.4
  • 62
    • 0036276503 scopus 로고    scopus 로고
    • Synthesis and properties of poly[N-(2-hydropxypropyl)methacrylamide] conjugates of superoxide dismutase
    • Šubr, V., Etrych, T., Ulbrich, K. et al. Synthesis and properties of poly[N-(2-hydropxypropyl)methacrylamide] conjugates of superoxide dismutase. J Bioact Comp Polym 2002, 17: 105-22.
    • (2002) J Bioact Comp Polym , vol.17 , pp. 105-122
    • Šubr, V.1    Etrych, T.2    Ulbrich, K.3
  • 63
    • 0033041990 scopus 로고    scopus 로고
    • Conjugates of semitelechelic poly[N-(2-hydroxypropyl)methacrylamide] with enzymes for protein delivery
    • Oupický, D., Ulbrich, K., Říhová, B. Conjugates of semitelechelic poly[N-(2-hydroxypropyl)methacrylamide] with enzymes for protein delivery. J Bioact Comp Polym 1999, 14: 213-31.
    • (1999) J Bioact Comp Polym , vol.14 , pp. 213-231
    • Oupický, D.1    Ulbrich, K.2    Říhová, B.3
  • 64
    • 0017388651 scopus 로고
    • Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase
    • Abuchowski, A., McCoy, J.R., Palczuk, N.C., Van Es, T., Davis, F.F. Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase. J Biol Chem 1977, 252: 3582-6.
    • (1977) J Biol Chem , vol.252 , pp. 3582-3586
    • Abuchowski, A.1    McCoy, J.R.2    Palczuk, N.C.3    Van Es, T.4    Davis, F.F.5
  • 65
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanisms of tumoritropic accumulation of proteins and the antitumor agent
    • Matsumura, Y., Maeda, H. A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanisms of tumoritropic accumulation of proteins and the antitumor agent. Cancer Res 1986, 6: 6387-92.
    • (1986) Cancer Res , vol.6 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 66
    • 1042277368 scopus 로고
    • Tumoritropic and lymphotropic principles of macromolecular drugs
    • Maeda, H., Matsumura, Y. Tumoritropic and lymphotropic principles of macromolecular drugs. CRC Crit Rev Ther Drug Carrier Syst 1992, 9: 135-87.
    • (1992) CRC Crit Rev Ther Drug Carrier Syst , vol.9 , pp. 135-187
    • Maeda, H.1    Matsumura, Y.2
  • 67
    • 0026926609 scopus 로고
    • Conjugates of anticancer agents and polymers: Advantages of macromolecular therapeutics in vivo
    • Maeda, H., Seymour, L.W., Miyamoto, Y. Conjugates of anticancer agents and polymers: Advantages of macromolecular therapeutics in vivo. Bioconj Chem 1992, 3: 351-5.
    • (1992) Bioconj Chem , vol.3 , pp. 351-355
    • Maeda, H.1    Seymour, L.W.2    Miyamoto, Y.3
  • 68
    • 0031959490 scopus 로고    scopus 로고
    • Early phase tumor accumulation of macromolecules: A great difference in clearance rate between tumor and normal tissues
    • Noguchi, Y., Wu, J., Duncan, R., Strohalm, J., Ulbrich, K., Akaike, T., Maeda, H. Early phase tumor accumulation of macromolecules: A great difference in clearance rate between tumor and normal tissues. Jpn J Cancer Res 1998, 89: 307-14.
    • (1998) Jpn J Cancer Res , vol.89 , pp. 307-314
    • Noguchi, Y.1    Wu, J.2    Duncan, R.3    Strohalm, J.4    Ulbrich, K.5    Akaike, T.6    Maeda, H.7
  • 69
    • 0009975408 scopus 로고
    • Polymer-bound derivatives of sarcolysin and their antitumour activity against mouse and human leukemia in vitro
    • Ulbrich, K., Zacharieva, E.I., Kopeček, J., Hume, I.C., Duncan, R. Polymer-bound derivatives of sarcolysin and their antitumour activity against mouse and human leukemia in vitro. Makromol Chem 1987, 188: 2497-509.
    • (1987) Makromol Chem , vol.188 , pp. 2497-2509
    • Ulbrich, K.1    Zacharieva, E.I.2    Kopeček, J.3    Hume, I.C.4    Duncan, R.5
  • 70
    • 0034049291 scopus 로고    scopus 로고
    • Efficacy of chemotherapeutic action of HPMA copolymer-bound doxorubicin in a solid tumor model of ovarian carcinoma
    • Minko, T., Kopečková, P., Kopeček, J. Efficacy of chemotherapeutic action of HPMA copolymer-bound doxorubicin in a solid tumor model of ovarian carcinoma. Intl J Cancer 2000, 86: 108-17.
    • (2000) Intl J Cancer , vol.86 , pp. 108-117
    • Minko, T.1    Kopečková, P.2    Kopeček, J.3
  • 71
  • 73
    • 0032959549 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic study of PK1 [N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin]: First member of a new class of chemotherapeutic agents-drug-polymer conjugates
    • Vasey, P.A., Kaye, S.B., Morrison, R. et al. Phase I clinical and pharmacokinetic study of PK1 [N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin]: First member of a new class of chemotherapeutic agents-drug-polymer conjugates. Clin Cancer Res 1999, 5: 83-94.
    • (1999) Clin Cancer Res , vol.5 , pp. 83-94
    • Vasey, P.A.1    Kaye, S.B.2    Morrison, R.3
  • 74
    • 0345404305 scopus 로고    scopus 로고
    • Receptor-mediated targeted drug or toxin delivery
    • Říhová, B. Receptor-mediated targeted drug or toxin delivery. Adv Drug Del Rev 1998, 29: 273-89.
    • (1998) Adv Drug Del Rev , vol.29 , pp. 273-289
    • Říhová, B.1
  • 75
    • 0025456160 scopus 로고
    • Selectivity of antibody-targeted anthracycline antibiotics on T lymphocytes
    • Říhová, B., Strohalm, J., Plocová, D., Ulbrich, K. Selectivity of antibody-targeted anthracycline antibiotics on T lymphocytes. J Bioact Comp Polym 1990, 5: 249-66.
    • (1990) J Bioact Comp Polym , vol.5 , pp. 249-266
    • Říhová, B.1    Strohalm, J.2    Plocová, D.3    Ulbrich, K.4
  • 77
    • 0142010620 scopus 로고    scopus 로고
    • Starlike versus classical macromolecular prodrugs: Two different antibody-targeted HPMA copolymers of doxorubicin studied in vitro and in vivo as potential anticancer drugs
    • Jelínková, M., Strohalm, J., Etrych, T., Ulbrich, K., Říhová, B. Starlike versus classical macromolecular prodrugs: Two different antibody-targeted HPMA copolymers of doxorubicin studied in vitro and in vivo as potential anticancer drugs. Pharm Res 2003, 20: 1558-64.
    • (2003) Pharm Res , vol.20 , pp. 1558-1564
    • Jelínková, M.1    Strohalm, J.2    Etrych, T.3    Ulbrich, K.4    Říhová, B.5
  • 78
    • 0022460432 scopus 로고
    • Evaluation of ricin A chain immunotoxins directed against human T cells
    • Press, O.W., Vitetta, E., Farr, A., Hansen, J., Martin, P. Evaluation of ricin A chain immunotoxins directed against human T cells. Cell Immunol 1986, 102: 10-20.
    • (1986) Cell Immunol , vol.102 , pp. 10-20
    • Press, O.W.1    Vitetta, E.2    Farr, A.3    Hansen, J.4    Martin, P.5
  • 79
    • 0023616248 scopus 로고
    • Comparison of two anti-Thy 1.1-abrin A-chain immunotoxins prepared with different cross-linking agents: Antitumor effects, in vivo fate, and tumor cell mutants
    • Thorpe, P.E., Blakey, D.C., Brown, A.N. et al. Comparison of two anti-Thy 1.1-abrin A-chain immunotoxins prepared with different cross-linking agents: Antitumor effects, in vivo fate, and tumor cell mutants. J Natl Cancer Inst 1987, 79: 1101-12.
    • (1987) J Natl Cancer Inst , vol.79 , pp. 1101-1112
    • Thorpe, P.E.1    Blakey, D.C.2    Brown, A.N.3
  • 80
    • 0024227006 scopus 로고
    • Ricin A-chain containing immunotoxins directed against different epitopes on the CD2 molecule differ in their ability to kill normal and malignant T cells
    • Press, O.W., Martin, J.P., Thorpe, P.E., Vitetta, E.S. Ricin A-chain containing immunotoxins directed against different epitopes on the CD2 molecule differ in their ability to kill normal and malignant T cells. J Immunol 1988, 141: 4410-7.
    • (1988) J Immunol , vol.141 , pp. 4410-4417
    • Press, O.W.1    Martin, J.P.2    Thorpe, P.E.3    Vitetta, E.S.4
  • 81
    • 0028863458 scopus 로고
    • Intracellular uptake and catabolism of anti-IgM antibodies and bispecific antibody-targeted hapten by B-lymphoma cells
    • Manetti, C. Le Doussal, J.M., Rouvier, E., Gruaz-Guyon, A., Barbet, J. Intracellular uptake and catabolism of anti-IgM antibodies and bispecific antibody-targeted hapten by B-lymphoma cells. Intl J Cancer 1995, 63: 250-6.
    • (1995) Intl J Cancer , vol.63 , pp. 250-256
    • Manetti, C.1    Le Doussal, J.M.2    Rouvier, E.3    Gruaz-Guyon, A.4    Barbet, J.5
  • 82
  • 83
    • 0025014603 scopus 로고
    • Improving the tumor retention of radioiodinated antibody: Aryl carbohydrate aducts
    • Ali, S.A., Waren, S.D., Richter, K.Y. et al. Improving the tumor retention of radioiodinated antibody: Aryl carbohydrate aducts. Cancer Res 1990, 50: 783s-8s.
    • (1990) Cancer Res , vol.50
    • Ali, S.A.1    Waren, S.D.2    Richter, K.Y.3
  • 84
    • 0041461022 scopus 로고    scopus 로고
    • Targeting of human and mouse T-lymphocytes by monoclonal antibody-HPMA copolymer-doxorubicin conjugates directed against different T-cell surface antigens
    • Jelínková, M., Strohalm, J., Plocová, D., Šubr, V., Št'astný, M., Ulbrich, K., Ří hová, B. Targeting of human and mouse T-lymphocytes by monoclonal antibody-HPMA copolymer-doxorubicin conjugates directed against different T-cell surface antigens. J Control Release 1998, 52: 253-70.
    • (1998) J Control Release , vol.52 , pp. 253-270
    • Jelínková, M.1    Strohalm, J.2    Plocová, D.3    Šubr, V.4    Št'astný, M.5    Ulbrich, K.6    Říhová, B.7
  • 86
    • 0026757191 scopus 로고
    • Drug-polymer conjugates: Potential for improved chemotherapy
    • Duncan, R. Drug-polymer conjugates: Potential for improved chemotherapy. Anticancer Drugs 1992, 3: 175-210.
    • (1992) Anticancer Drugs , vol.3 , pp. 175-210
    • Duncan, R.1
  • 87
    • 0024318447 scopus 로고
    • Action of polymeric prodrugs based on N-(2-hydroxypropyl)methacrylamide copolymers. I. Suppression of the antibody response and proliferation of mouse splenocytes in vivo
    • Říhová, B., Větvička, V., Strohalm, J., Ulbrich, K., Kopeček, J. Action of polymeric prodrugs based on N-(2-hydroxypropyl)methacrylamide copolymers. I. Suppression of the antibody response and proliferation of mouse splenocytes in vivo. J Control Release 1989, 9: 21-32.
    • (1989) J Control Release , vol.9 , pp. 21-32
    • Říhová, B.1    Větvička, V.2    Strohalm, J.3    Ulbrich, K.4    Kopeček, J.5
  • 88
    • 0027482188 scopus 로고
    • Targeting of an activated T-cell subset using a bispecific antibody-toxin conjugate directed against CD4 and CD26
    • Duke-Cohan, J.S., Morimoto, Ch., Schlossman, S.F. Targeting of an activated T-cell subset using a bispecific antibody-toxin conjugate directed against CD4 and CD26. Blood 1993, 82: 2224-34.
    • (1993) Blood , vol.82 , pp. 2224-2234
    • Duke-Cohan, J.S.1    Morimoto, Ch.2    Schlossman, S.F.3
  • 90
    • 0000859980 scopus 로고
    • Polymers containing enzymatically degradable bonds, 8. Degradation of oligopeptide sequences in N-(2-hydroxypropyl) methacrylamide copolymers by bovine spleen cathepsin B
    • Rejmanová, P., Kopeček, J., Pohl, J., Baudyš, M., Kostka, V. Polymers containing enzymatically degradable bonds, 8. Degradation of oligopeptide sequences in N-(2-hydroxypropyl) methacrylamide copolymers by bovine spleen cathepsin B. Makromol Chem 1983, 184: 2009-20.
    • (1983) Makromol Chem , vol.184 , pp. 2009-2020
    • Rejmanová, P.1    Kopeček, J.2    Pohl, J.3    Baudyš, M.4    Kostka, V.5
  • 91
    • 0026512810 scopus 로고
    • Evaluation of protein-N-(2-hydroxypropyl)methacrylamide copolymer conjugates as targetable drug-carriers. 2. Body distribution of conjugates containing transferrin, antitransferrin receptor antibody or anti-Thy 1.2 antibody and effectiveness of transferrin-containing daunomycin conjugates against mouse L1210 leukaemia in vivo
    • Flanagan, P.A., Duncan, R., Šubr, V., Ulbrich, K., Kopečková, P., Kopeček, J. Evaluation of protein-N-(2-hydroxypropyl)methacrylamide copolymer conjugates as targetable drug-carriers. 2. Body distribution of conjugates containing transferrin, antitransferrin receptor antibody or anti-Thy 1.2 antibody and effectiveness of transferrin-containing daunomycin conjugates against mouse L1210 leukaemia in vivo. J Control Release 1992, 18: 25-38.
    • (1992) J Control Release , vol.18 , pp. 25-38
    • Flanagan, P.A.1    Duncan, R.2    Šubr, V.3    Ulbrich, K.4    Kopečková, P.5    Kopeček, J.6
  • 94
    • 0035907178 scopus 로고    scopus 로고
    • New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: Synthesis and preliminary in vitro and in vivo biological properties
    • Etrych, T., Jelínková, M., Říhová, B., Ulbrich, K. New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: Synthesis and preliminary in vitro and in vivo biological properties. J Control Release 2001, 73: 89-102.
    • (2001) J Control Release , vol.73 , pp. 89-102
    • Etrych, T.1    Jelínková, M.2    Říhová, B.3    Ulbrich, K.4
  • 95
    • 0035816157 scopus 로고    scopus 로고
    • Doxorubicin bound to a HPMA copolymer carrier through hydrazone bond is effective also in a cancer cell line with a limited content of lysosomes
    • Říhová, B., Etrych, T., Pechar, M. et al. Doxorubicin bound to a HPMA copolymer carrier through hydrazone bond is effective also in a cancer cell line with a limited content of lysosomes. J Control Release 2001, 74: 225-32.
    • (2001) J Control Release , vol.74 , pp. 225-232
    • Říhová, B.1    Etrych, T.2    Pechar, M.3
  • 96
    • 0037458920 scopus 로고    scopus 로고
    • HPMA copolymers with pH-controlled release of doxorubicin in vitro cytotoxicity and in vivo antitumor activity
    • Ulbrich, K., Etrych, T., Chytil, P., Jelínková, M., Říhová, B. HPMA copolymers with pH-controlled release of doxorubicin in vitro cytotoxicity and in vivo antitumor activity. J Control Release 2003, 87: 33-47.
    • (2003) J Control Release , vol.87 , pp. 33-47
    • Ulbrich, K.1    Etrych, T.2    Chytil, P.3    Jelínková, M.4    Říhová, B.5
  • 97
    • 0030042022 scopus 로고    scopus 로고
    • HPMA copolymer - Anticancer drug - OV-TL16 antibody conjugates. 1. Influence of the method of synthesis on the binding affinity to OVCAR-3 ovarian carcinoma cells in vitro
    • Omelyanenko, V., Kopečková, P., Gentry, C., Shiah, J.-G., Kopeček, J. HPMA copolymer - anticancer drug - OV-TL16 antibody conjugates. 1. Influence of the method of synthesis on the binding affinity to OVCAR-3 ovarian carcinoma cells in vitro. J Drug Target 1996, 3: 357-73.
    • (1996) J Drug Target , vol.3 , pp. 357-373
    • Omelyanenko, V.1    Kopečková, P.2    Gentry, C.3    Shiah, J.-G.4    Kopeček, J.5
  • 99
    • 0342316475 scopus 로고    scopus 로고
    • Polymeric drugs based on conjugates of synthetic and natural macromolecules. I. Synthesis and physico-chemical characterization
    • Ulbrich, K., Šubr, V., Strohalm, J., Plocová, D., Jelínková, M., Říhová, B. Polymeric drugs based on conjugates of synthetic and natural macromolecules. I. Synthesis and physico-chemical characterization. J Control Release 2000, 64: 63-79.
    • (2000) J Control Release , vol.64 , pp. 63-79
    • Ulbrich, K.1    Šubr, V.2    Strohalm, J.3    Plocová, D.4    Jelínková, M.5    Říhová, B.6
  • 100
    • 0344146604 scopus 로고    scopus 로고
    • Polymerizable Fab' antibody fragments for targeting of anticancer drugs
    • Lu, Z.-R., Kopečková, P., Kopeček, J. Polymerizable Fab' antibody fragments for targeting of anticancer drugs. Nature Biotechnol 1999, 17: 1101-4.
    • (1999) Nature Biotechnol , vol.17 , pp. 1101-1104
    • Lu, Z.-R.1    Kopečková, P.2    Kopeček, J.3
  • 101
    • 0344103248 scopus 로고
    • In vivo therapy with monoclonal anti-I-A antibody suppresses immune responses to acetylcholine receptor
    • Waldor, M.K., Sriram, S., McDevitt, H.O., Steinman, L. In vivo therapy with monoclonal anti-I-A antibody suppresses immune responses to acetylcholine receptor. Proc Natl Acad Sci USA 1983, 80: 2713-7.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 2713-2717
    • Waldor, M.K.1    Sriram, S.2    McDevitt, H.O.3    Steinman, L.4
  • 102
    • 0018696482 scopus 로고
    • Sensitivity to chemotherapeutic and immunomodulating agents of two mouse lymphomas and of a macrophage tumor
    • Tarnowski, G.S., Ralph, P., Stock, C.Ch. Sensitivity to chemotherapeutic and immunomodulating agents of two mouse lymphomas and of a macrophage tumor. Cancer Res 1979, 39: 3964-7.
    • (1979) Cancer Res , vol.39 , pp. 3964-3967
    • Tarnowski, G.S.1    Ralph, P.2    Stock, C.Ch.3
  • 103
    • 9044226134 scopus 로고    scopus 로고
    • Applicability of monoclonal antibody Fab fragments as a carrier of neocarzinostatin in targeting chemotherapy
    • Otsuji, E., Yamaguchi, T., Tsuruta, H. et al. Applicability of monoclonal antibody Fab fragments as a carrier of neocarzinostatin in targeting chemotherapy. J Surg Oncol 1996, 61: 149-54.
    • (1996) J Surg Oncol , vol.61 , pp. 149-154
    • Otsuji, E.1    Yamaguchi, T.2    Tsuruta, H.3
  • 104
    • 0030992080 scopus 로고    scopus 로고
    • Factors influencing the in vivo pharmacokinetics of peptides and antibody fragments: The pharmacokinetics of two PET-labeled low molecular weight proteins
    • Lang, L., Jagoda, E., Wu, C. et al. Factors influencing the in vivo pharmacokinetics of peptides and antibody fragments: The pharmacokinetics of two PET-labeled low molecular weight proteins. Q J Nucl Med 1997, 41: 53-61.
    • (1997) Q J Nucl Med , vol.41 , pp. 53-61
    • Lang, L.1    Jagoda, E.2    Wu, C.3
  • 105
    • 0025912062 scopus 로고
    • Monoclonal antibodies in diagnosis and therapy
    • Waldmann, T.A. Monoclonal antibodies in diagnosis and therapy. Science 1991, 252: 1657-62.
    • (1991) Science , vol.252 , pp. 1657-1662
    • Waldmann, T.A.1
  • 107
    • 0027474795 scopus 로고
    • Efficacy of transferrin receptor-targeted immunotoxins in brain tumor cell lines and pediatric brain tumors
    • Martell, L.A., Agrawal, A., Ross, D.A., Muraszko, K.M. Efficacy of transferrin receptor-targeted immunotoxins in brain tumor cell lines and pediatric brain tumors. Cancer Res 1993, 53: 1348-53.
    • (1993) Cancer Res , vol.53 , pp. 1348-1353
    • Martell, L.A.1    Agrawal, A.2    Ross, D.A.3    Muraszko, K.M.4
  • 108
    • 0031797454 scopus 로고    scopus 로고
    • Cell-type-specific gene transfer into human cells with retroviral vectors that display single-chain antibodies
    • Jiang, A., Chu, T.H., Nocken, F., Cichutek, K., Dornburg, R. Cell-type-specific gene transfer into human cells with retroviral vectors that display single-chain antibodies. J Virol 1998, 72: 10148-56.
    • (1998) J Virol , vol.72 , pp. 10148-10156
    • Jiang, A.1    Chu, T.H.2    Nocken, F.3    Cichutek, K.4    Dornburg, R.5
  • 111
    • 0025088879 scopus 로고
    • Comparative in vitro binding characteristics and biodistribution in tumor-bearing athymic mice of anti-ovarian carcinoma monoclonal antibodies
    • Boerman, O., Massuger, L., Makkink, K., Thomas, C., Kenemans, P., Poels, L. Comparative in vitro binding characteristics and biodistribution in tumor-bearing athymic mice of anti-ovarian carcinoma monoclonal antibodies. Anticancer Res 1990, 10: 1289-96.
    • (1990) Anticancer Res , vol.10 , pp. 1289-1296
    • Boerman, O.1    Massuger, L.2    Makkink, K.3    Thomas, C.4    Kenemans, P.5    Poels, L.6
  • 112
    • 0346551010 scopus 로고
    • Polymer conjugates with anticancer activity
    • Putnam, D., Kopeček, J. Polymer conjugates with anticancer activity. Adv Polym Sci 1995, 122: 55-123.
    • (1995) Adv Polym Sci , vol.122 , pp. 55-123
    • Putnam, D.1    Kopeček, J.2
  • 113
    • 0023627395 scopus 로고
    • Doxorubicin concentration time course in the myocardium after single administration to the dog
    • Timour, Q., Nony, P., Lang, J., Lakhal, M., Trillet, V., Faucon, G. Doxorubicin concentration time course in the myocardium after single administration to the dog. Cancer Chemother 1987, 20: 267-9.
    • (1987) Cancer Chemother , vol.20 , pp. 267-269
    • Timour, Q.1    Nony, P.2    Lang, J.3    Lakhal, M.4    Trillet, V.5    Faucon, G.6
  • 114
    • 0023488816 scopus 로고
    • Doxorubicin distribution in human breast cancer
    • Rossi C., Gasparini, G., Canobbio, L. et al. Doxorubicin distribution in human breast cancer. Cancer Treat Rep 1987, 71: 1221-6.
    • (1987) Cancer Treat Rep , vol.71 , pp. 1221-1226
    • Rossi, C.1    Gasparini, G.2    Canobbio, L.3
  • 115
    • 0021349406 scopus 로고
    • Acute doxorubicin toxicity. Relationship to pretreatment, liver function, response and pharmacokinetics in patients with acute nonlymphocytic leukemia
    • Brenner, D.E., Wiernik, P.H., Wesley, M., Bachur, N.R. Acute doxorubicin toxicity. Relationship to pretreatment, liver function, response and pharmacokinetics in patients with acute nonlymphocytic leukemia. Cancer 1984, 53: 1042-8.
    • (1984) Cancer , vol.53 , pp. 1042-1048
    • Brenner, D.E.1    Wiernik, P.H.2    Wesley, M.3    Bachur, N.R.4
  • 116
    • 0021189245 scopus 로고
    • Pharmacokinetic study of the mechanism of tissue distribution of doxorubicin. Inter-organ and inter-species variation in tissue to plasma partition coefficients in rats, rabbits and guinea pigs
    • Terasaki, T., Iga, T., Sugiyama, Y., Hanano, M. Pharmacokinetic study of the mechanism of tissue distribution of doxorubicin. Inter-organ and inter-species variation in tissue to plasma partition coefficients in rats, rabbits and guinea pigs. J Pharm Sci 1984, 73: 1359-62.
    • (1984) J Pharm Sci , vol.73 , pp. 1359-1362
    • Terasaki, T.1    Iga, T.2    Sugiyama, Y.3    Hanano, M.4
  • 117
    • 0023450012 scopus 로고
    • Effect of molecular weight (MW) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats
    • Seymour, L.W., Duncan, R., Strohalm, J., Kopeček, J. Effect of molecular weight (MW) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats. J Biomed Mater Res 1987, 21: 1341-58.
    • (1987) J Biomed Mater Res , vol.21 , pp. 1341-1358
    • Seymour, L.W.1    Duncan, R.2    Strohalm, J.3    Kopeček, J.4
  • 118
    • 0021271357 scopus 로고
    • Tyrosinamide residues enhance pinocytic capture of N-(2-hydroxypropyl)methacrylamide copolymers
    • Duncan, R., Cable, H.C., Rejmanová, P., Kopeček, J., Lloyd, J.B. Tyrosinamide residues enhance pinocytic capture of N-(2-hydroxypropyl)methacrylamide copolymers. Biochim Biophys Acta 1984, 799: 1-8.
    • (1984) Biochim Biophys Acta , vol.799 , pp. 1-8
    • Duncan, R.1    Cable, H.C.2    Rejmanová, P.3    Kopeček, J.4    Lloyd, J.B.5
  • 120
    • 0024849184 scopus 로고
    • Immunotoxins: A clinical review of their use in the treatment of malignancies
    • Hertler, A.A., Frankel, A.E. Immunotoxins: A clinical review of their use in the treatment of malignancies. J Clin Oncol 1989, 7: 1932-42.
    • (1989) J Clin Oncol , vol.7 , pp. 1932-1942
    • Hertler, A.A.1    Frankel, A.E.2
  • 122
    • 0025918134 scopus 로고
    • Reduced cardiotoxicyty of doxorubicin given in the form of N-(2-hydroxypropyl)methacrylamide cojugates: An experimental study in the rat
    • Yeung, T.K., Hopewell, J.W., Simmonds, R.H. et al. Reduced cardiotoxicyty of doxorubicin given in the form of N-(2-hydroxypropyl)methacrylamide cojugates: An experimental study in the rat. Cancer Chemother Pharmacol 1991, 29: 105-11.
    • (1991) Cancer Chemother Pharmacol , vol.29 , pp. 105-111
    • Yeung, T.K.1    Hopewell, J.W.2    Simmonds, R.H.3
  • 123
    • 0035667083 scopus 로고    scopus 로고
    • Preclinical evaluation of the cardiotoxicity of PK2: A novel HPMA copolymer-doxorubicin-galactosamine conjugate antitumour agent
    • Hopewell, J.W., Duncan, R., Wilding, D., Chakrabarti, K. Preclinical evaluation of the cardiotoxicity of PK2: A novel HPMA copolymer-doxorubicin-galactosamine conjugate antitumour agent. Hum Exp Toxicol 2001, 20: 461-70.
    • (2001) Hum Exp Toxicol , vol.20 , pp. 461-470
    • Hopewell, J.W.1    Duncan, R.2    Wilding, D.3    Chakrabarti, K.4
  • 124
    • 2142809327 scopus 로고    scopus 로고
    • Immunoprotective therapy with targeted anticancer drugs
    • Říhová, B., Strohalm, J., Hoste, K. et al. Immunoprotective therapy with targeted anticancer drugs. Makromol Symp 2001, 172: 21-8.
    • (2001) Makromol Symp , vol.172 , pp. 21-28
    • Říhová, B.1    Strohalm, J.2    Hoste, K.3
  • 125
    • 0022611270 scopus 로고
    • Effect of a synthetic poly-N-(2-hydroxypropyl)methacrylamide (DUXON) on haemopoiesis and graft-versus-host reaction
    • Paluska, E., Hrubá, A., Šterba, O., Kopeček, J. Effect of a synthetic poly-N-(2-hydroxypropyl)methacrylamide (DUXON) on haemopoiesis and graft-versus-host reaction. Folia Biol 1986, 32: 91-102.
    • (1986) Folia Biol , vol.32 , pp. 91-102
    • Paluska, E.1    Hrubá, A.2    Šterba, O.3    Kopeček, J.4
  • 126
    • 0024329881 scopus 로고
    • The biochemistry of P-glycoprotein-mediated multidrug resistance
    • Endicott, J.A., Ling, V. The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu Rev Biochem 1989, 58: 137-71.
    • (1989) Annu Rev Biochem , vol.58 , pp. 137-171
    • Endicott, J.A.1    Ling, V.2
  • 127
    • 0027474456 scopus 로고
    • How cancer cells evade chemotherapy: Sixteenth Richard and Hinda Rosenthal Foundation Award Lecture
    • Gottesman, M.M. How cancer cells evade chemotherapy: Sixteenth Richard and Hinda Rosenthal Foundation Award Lecture. Cancer Res 1993, 53: 747-54.
    • (1993) Cancer Res , vol.53 , pp. 747-754
    • Gottesman, M.M.1
  • 128
    • 0028861933 scopus 로고
    • P-glycoprotein-a marker of cancer-cell behavior
    • Pinedo, H.M., Giaccone, G. P-glycoprotein-a marker of cancer-cell behavior. New Engl J Med 1995, 333: 1417-9.
    • (1995) New Engl J Med , vol.333 , pp. 1417-1419
    • Pinedo, H.M.1    Giaccone, G.2
  • 129
    • 0344142519 scopus 로고    scopus 로고
    • Chronic exposure to HPMA copolymer-bound adriamycin does not induce multidrug resistance in a human ovarian carcinoma cell fine
    • Minko, T., Kopečková, P., Kopeček, J. Chronic exposure to HPMA copolymer-bound adriamycin does not induce multidrug resistance in a human ovarian carcinoma cell fine. J Control Release 1999, 59: 133-48.
    • (1999) J Control Release , vol.59 , pp. 133-148
    • Minko, T.1    Kopečková, P.2    Kopeček, J.3
  • 130
    • 0026073833 scopus 로고
    • CD4 and CD7 molecules are targets for drug delivery from antibody bearing liposomes
    • Suzuki, H., Zelphati, O., Hildebrand, G., Leserman, L. CD4 and CD7 molecules are targets for drug delivery from antibody bearing liposomes. Exp Cell Res 1991, 193: 112-9.
    • (1991) Exp Cell Res , vol.193 , pp. 112-119
    • Suzuki, H.1    Zelphati, O.2    Hildebrand, G.3    Leserman, L.4
  • 132
    • 0029765581 scopus 로고    scopus 로고
    • Hypersensitizing effect of pluronic L61 on cytotoxic activity, transport and subcellular distribution of doxorubicin in multi-drug resistant cells
    • Venne, A., Li, S., Mandeville, R., Kabanov, A., Alakhov, V. Hypersensitizing effect of pluronic L61 on cytotoxic activity, transport and subcellular distribution of doxorubicin in multi-drug resistant cells. Cancer Res 1996, 56: 3626-9.
    • (1996) Cancer Res , vol.56 , pp. 3626-3629
    • Venne, A.1    Li, S.2    Mandeville, R.3    Kabanov, A.4    Alakhov, V.5
  • 133
    • 0030111359 scopus 로고    scopus 로고
    • Hypersensitization of multidrug resistant human ovarian carcinoma cells by pluronic P85 block copolymer
    • Alakhov, V.Y., Moskaleva, E.U., Batrakova, E.V. Kabanov, A. Hypersensitization of multidrug resistant human ovarian carcinoma cells by pluronic P85 block copolymer. Bioconj Chem 1996, 7: 209-16.
    • (1996) Bioconj Chem , vol.7 , pp. 209-216
    • Alakhov, V.Y.1    Moskaleva, E.U.2    Batrakova, E.V.3    Kabanov, A.4
  • 134
    • 0035212257 scopus 로고    scopus 로고
    • Drug transporters in the central nervous system: Brain barriers and brain parenchyma consideration
    • Dallas, G. et al. Drug transporters in the central nervous system: Brain barriers and brain parenchyma consideration. Pharmacol Rev 2001, 53: 569-96.
    • (2001) Pharmacol Rev , vol.53 , pp. 569-596
    • Dallas, G.1
  • 135
    • 0036808041 scopus 로고    scopus 로고
    • Therapeutic synthetic polymers: A game of Russian roulette?
    • Hunter, A.Ch., Moghimi, S.M. Therapeutic synthetic polymers: A game of Russian roulette? DDT 2002, 7: 998-1001.
    • (2002) DDT , vol.7 , pp. 998-1001
    • Hunter, A.Ch.1    Moghimi, S.M.2
  • 137
    • 0034113617 scopus 로고    scopus 로고
    • HSP70 stimulates cytokine production through a CD 14-dependent pathway, demonstrating its dual role as a chaperone and cytokine
    • Asea, A., Kraeft., S.K., Kurt-Jones, E.A. et al. HSP70 stimulates cytokine production through a CD 14-dependent pathway, demonstrating its dual role as a chaperone and cytokine. Nature Med 2000, 6: 435-42.
    • (2000) Nature Med , vol.6 , pp. 435-442
    • Asea, A.1    Kraeft, S.K.2    Kurt-Jones, E.A.3
  • 138
    • 0032101221 scopus 로고    scopus 로고
    • Heat shock proteins come of age: Primitive functions acquire new roles in an adaptive world
    • Srivastava, P.K., Menoret, A., Basu, S., Binder, R.J., McQuade, K.L. Heat shock proteins come of age: Primitive functions acquire new roles in an adaptive world. Immunity 1998, 8: 657-65.
    • (1998) Immunity , vol.8 , pp. 657-665
    • Srivastava, P.K.1    Menoret, A.2    Basu, S.3    Binder, R.J.4    McQuade, K.L.5
  • 139
    • 0028114348 scopus 로고
    • Heat shock protein-peptide complexes in cancer immunotherapy
    • Srivastava, P.K., Udono, H. Heat shock protein-peptide complexes in cancer immunotherapy. Curr Opin Immunol 1994, 6: 728-32.
    • (1994) Curr Opin Immunol , vol.6 , pp. 728-732
    • Srivastava, P.K.1    Udono, H.2
  • 140
    • 0034601832 scopus 로고    scopus 로고
    • Time- and concentration-dependent apoptosis and necrosis induced by free and HPMA copolymer-bound doxorubicin in human ovarian carcinoma cells
    • Demoy, M., Minko, T., Kopečková, P., Kopeček, J. Time- and concentration-dependent apoptosis and necrosis induced by free and HPMA copolymer-bound doxorubicin in human ovarian carcinoma cells. J Control Release 2000, 69: 185-96.
    • (2000) J Control Release , vol.69 , pp. 185-196
    • Demoy, M.1    Minko, T.2    Kopečková, P.3    Kopeček, J.4
  • 142
    • 0029935682 scopus 로고    scopus 로고
    • Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells
    • Friesen, C., Herr, I., Krammer, P.H., Debatin, K.M. Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nature Med 1996, 2: 574-7.
    • (1996) Nature Med , vol.2 , pp. 574-577
    • Friesen, C.1    Herr, I.2    Krammer, P.H.3    Debatin, K.M.4
  • 143
    • 0032742205 scopus 로고    scopus 로고
    • Cytotoxic drugs and the CD95 pathway
    • Friesen, C., Fulda, S., Debatin, K.M. Cytotoxic drugs and the CD95 pathway. Leukemia 1999, 13: 1854-8.
    • (1999) Leukemia , vol.13 , pp. 1854-1858
    • Friesen, C.1    Fulda, S.2    Debatin, K.M.3
  • 144
    • 0032789159 scopus 로고    scopus 로고
    • Gamma-globulin inhibits tumor spread in mice
    • Shoenfeld, Y., Fishman, P. Gamma-globulin inhibits tumor spread in mice. Intl Immunol 1999, 11: 1247-52.
    • (1999) Intl Immunol , vol.11 , pp. 1247-1252
    • Shoenfeld, Y.1    Fishman, P.2
  • 145
    • 0032867961 scopus 로고    scopus 로고
    • Population pharmacokinetics in phase I drug development: A phase I study of PK1 in patients with solid tumours
    • Thomson, A.H., Vasey, P.A., Murray, L.S., Cassidy, J., Fraier D., Frigerio, E., Twelves, C. Population pharmacokinetics in phase I drug development: A phase I study of PK1 in patients with solid tumours. Br J Cancer 1999, 81: 99-107.
    • (1999) Br J Cancer , vol.81 , pp. 99-107
    • Thomson, A.H.1    Vasey, P.A.2    Murray, L.S.3    Cassidy, J.4    Fraier, D.5    Frigerio, E.6    Twelves, C.7


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