Time- and concentration-dependent apoptosis and necrosis induced by free and HPMA copolymer-bound doxorubicin in human ovarian carcinoma cells

Journal of Controlled Release

Volumn 69, Issue 1, 2000, Pages 185-196

  Demoy, Marina ^a   Minko, Tamara ^a   Kopečková, Pavla ^a,b   Kopeček, Jindřich ^a,b  

^a UNIVERSITY OF UTAH   (United States)

^b Department of Electrical and Computer Engineering   (United States)

Author keywords

Apoptosis; Doxorubicin; HPMA copolymer; Necrosis; Ovarian carcinoma

Indexed keywords

DOXORUBICIN; OLIGOPEPTIDE; POLYMER;

APOPTOSIS; ARTICLE; CELL DEATH; CELL METABOLISM; CONCENTRATION RESPONSE; CYTOTOXICITY; DOSE TIME EFFECT RELATION; FLOW CYTOMETRY; HUMAN; MEMBRANE PERMEABILITY; MITOCHONDRIAL RESPIRATION; OVARY CARCINOMA; PRIORITY JOURNAL;

ADULT; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; DOXORUBICIN; FEMALE; GENES, MDR; HUMANS; METHACRYLATES; MITOCHONDRIA; NECROSIS; OVARIAN NEOPLASMS; PHOSPHATIDYLSERINES; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0034601832     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(00)00301-1     Document Type: Article

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