-
1
-
-
0026791975
-
The immune system evolved to discriminate infectious nonself from noninfectious self
-
Janeway Jr CA. The immune system evolved to discriminate infectious nonself from noninfectious self. Immunol Today 1992; 13: 11-16.
-
(1992)
Immunol. Today
, vol.13
, pp. 11-16
-
-
Janeway Jr., C.A.1
-
2
-
-
0031905311
-
A family of human receptors structurally related to Drosophila Toll
-
Rock FL, Hardiman G, Timans JC, Kastelein RA, Bazan JF. A family of human receptors structurally related to Drosophila Toll. Proc Natl Acad Sci USA 1998; 95: 588-593.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 588-593
-
-
Rock, F.L.1
Hardiman, G.2
Timans, J.C.3
Kastelein, R.A.4
Bazan, J.F.5
-
4
-
-
0032191916
-
An innate sense of danger
-
Matzinger P. An innate sense of danger. Semin Immunol 1998; 10: 399-415.
-
(1998)
Semin. Immunol.
, vol.10
, pp. 399-415
-
-
Matzinger, P.1
-
5
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
Krieg AM, Yi AK, Matson S et al. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 1995; 374 546-549.
-
(1995)
Nature
, vol.374
, pp. 546-549
-
-
Krieg, A.M.1
Yi, A.K.2
Matson, S.3
-
6
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H, Takeuchi O, Kawai T et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000; 408: 740-745.
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
-
7
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via Toll-like receptors 7 and 8
-
Heil F, Hemmi H, Hochrein H et al. Species-specific recognition of single-stranded RNA via Toll-like receptors 7 and 8. Science 2004; 303: 1526-1529.
-
(2004)
Science
, vol.303
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
-
8
-
-
0036219195
-
CpG motifs in bacterial DNA and their immune effects
-
Krieg AM. CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 2002; 20: 709-760.
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 709-760
-
-
Krieg, A.M.1
-
9
-
-
0033529891
-
CpG DNA: A potent signal for growth, activation, and maturation of human dendritic cells
-
Hartmann G, Weiner GJ, Krieg AM. CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells. Proc Natl Acad Sci USA 1999; 96: 9305-9310.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9305-9310
-
-
Hartmann, G.1
Weiner, G.J.2
Krieg, A.M.3
-
10
-
-
0038236749
-
Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-alpha induction in plasmacytoid dendritic cells
-
Hartmann G, Battiany J, Poeck H et al. Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-alpha induction in plasmacytoid dendritic cells. Eur J Immunol 2003; 33: 1633-1641.
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 1633-1641
-
-
Hartmann, G.1
Battiany, J.2
Poeck, H.3
-
11
-
-
0034933019
-
Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells
-
Krug A, Rothenfusser S, Hornung V et al. Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells. Eur J Immunol 2001; 31: 2154-2163.
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 2154-2163
-
-
Krug, A.1
Rothenfusser, S.2
Hornung, V.3
-
12
-
-
0036587573
-
Differential and competitive activation of human immune cells by distinct classes of CpG oligodeoxynucleotide
-
Gursel M, Verthelyi D, Gursel I, Ishii KJ, Klimnan DM. Differential and competitive activation of human immune cells by distinct classes of CpG oligodeoxynucleotide. J Leukoc Biol 2002; 71: 813-820.
-
(2002)
J. Leukoc. Biol.
, vol.71
, pp. 813-820
-
-
Gursel, M.1
Verthelyi, D.2
Gursel, I.3
Ishii, K.J.4
Klimnan, D.M.5
-
13
-
-
0035839057
-
The role of DNA methylation in mammalian epigenetics
-
Jones PA, Takai D. The role of DNA methylation in mammalian epigenetics. Science 2001; 293: 1068-1070.
-
(2001)
Science
, vol.293
, pp. 1068-1070
-
-
Jones, P.A.1
Takai, D.2
-
14
-
-
0023318626
-
Non-methylated CpG-rich islands at the human alpha-globin locus: Implications for evolution of the alpha-globin pseudogene
-
Bird AP, Taggart MH, Nicholls RD, Higgs DR. Non-methylated CpG-rich islands at the human alpha-globin locus: implications for evolution of the alpha-globin pseudogene. EMBO J 1987; 6: 999-1004.
-
(1987)
EMBO J.
, vol.6
, pp. 999-1004
-
-
Bird, A.P.1
Taggart, M.H.2
Nicholls, R.D.3
Higgs, D.R.4
-
15
-
-
0033615717
-
DNA methyltransferases Dmnt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M, Bell DW, Haber DA, Li E. DNA methyltransferases Dmnt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999; 99: 247-257.
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
16
-
-
0025005442
-
In vivo footprint and methylation analysis by PCR-aided genomic sequencing: Comparison of active and inactive X chromosomal DNA at the CpG island and promoter of human PGK-1
-
Pfeifer GP, Tanguay RL, Steigerwald SD, Riggs AD. In vivo footprint and methylation analysis by PCR-aided genomic sequencing: comparison of active and inactive X chromosomal DNA at the CpG island and promoter of human PGK-1. Genes Dev 1990; 4: 1277-1287.
-
(1990)
Genes Dev.
, vol.4
, pp. 1277-1287
-
-
Pfeifer, G.P.1
Tanguay, R.L.2
Steigerwald, S.D.3
Riggs, A.D.4
-
17
-
-
0034176798
-
DNA hypermethylation in tumorigenesis: Epigenetics joins genetics
-
Baylin SB, Herman JG. DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 2000; 16: 168-174.
-
(2000)
Trends Genet.
, vol.16
, pp. 168-174
-
-
Baylin, S.B.1
Herman, J.G.2
-
18
-
-
0142216213
-
Methylation and demethylation in the regulation of genes, cells, and responses in the immune system
-
Fitzpatrick DR, Wilson CB. Methylation and demethylation in the regulation of genes, cells, and responses in the immune system. Clin Immunol 2003; 109: 37-45.
-
(2003)
Clin. Immunol.
, vol.109
, pp. 37-45
-
-
Fitzpatrick, D.R.1
Wilson, C.B.2
-
19
-
-
0024557292
-
Antibody binding of macromolecular DNA and RNA in the plasma of SLE patients
-
Krapf F, Herrmann M, Leitmann W, Kalden JR. Antibody binding of macromolecular DNA and RNA in the plasma of SLE patients. Clin Exp Immunol 1989; 75: 336-342.
-
(1989)
Clin. Exp. Immunol.
, vol.75
, pp. 336-342
-
-
Krapf, F.1
Herrmann, M.2
Leitmann, W.3
Kalden, J.R.4
-
20
-
-
0024375817
-
Binding properties of human anti-DNA antibodies to cloned human DNA fragments
-
Sano H, Takai O, Harata N, Yoshinaga K, Kodama-Kamada I, Sasaki T. Binding properties of human anti-DNA antibodies to cloned human DNA fragments. Scand J Immunol 1989; 30: 51-63.
-
(1989)
Scand. J. Immunol.
, vol.30
, pp. 51-63
-
-
Sano, H.1
Takai, O.2
Harata, N.3
Yoshinaga, K.4
Kodama-Kamada, I.5
Sasaki, T.6
-
21
-
-
0020676675
-
Accumulation of guanine-cytosine-enriched low M.W. DNA fragments in lymphocytes of patients with systemic lupus erythematosus
-
Sano H, Imokawa M, Steinberg AD, Morimoto C. Accumulation of guanine-cytosine-enriched low M.W. DNA fragments in lymphocytes of patients with systemic lupus erythematosus. J Immunol 1983; 130 187-190.
-
(1983)
J. Immunol.
, vol.130
, pp. 187-190
-
-
Sano, H.1
Imokawa, M.2
Steinberg, A.D.3
Morimoto, C.4
-
22
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
-
Leadbetter EA, Rifkin IR, Hohlbaum AM, Beaudette BC, Shlomchik MJ, Marshak-Rothstein A. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 2002; 416: 603-607.
-
(2002)
Nature
, vol.416
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
23
-
-
0034254310
-
Immune complexes present in the sera of autoimmune mice activate rheumatoid factor B cells
-
Rifkin IR, Leadbetter EA, Beaudette BC et al. Immune complexes present in the sera of autoimmune mice activate rheumatoid factor B cells. J Immunol 2000; 165: 1626-1633.
-
(2000)
J. Immunol.
, vol.165
, pp. 1626-1633
-
-
Rifkin, I.R.1
Leadbetter, E.A.2
Beaudette, B.C.3
-
24
-
-
0347480224
-
Activation of autoreactive B cells by CpG dsDNA
-
Viglianti GA, Lau CM, Hanley TM, Miko BA, Shlomchik MJ, Marshak-Rothstein A. Activation of autoreactive B cells by CpG dsDNA. Immunity 2003; 19: 837-847.
-
(2003)
Immunity
, vol.19
, pp. 837-847
-
-
Viglianti, G.A.1
Lau, C.M.2
Hanley, T.M.3
Miko, B.A.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
26
-
-
3042548183
-
Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes
-
Boule MW, Broughton C, Mackay F, Akira S, Marshak-Rothstein A, Rifkin IR. Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes. J Exp Med 2004; 199: 1631-1640.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1631-1640
-
-
Boule, M.W.1
Broughton, C.2
Mackay, F.3
Akira, S.4
Marshak-Rothstein, A.5
Rifkin, I.R.6
-
27
-
-
0141768248
-
Importance of extra- and intracellular domains of TLR1 and TLR2 in NF-kappa B signaling
-
Sandor F, Latz E, Re F et al. Importance of extra- and intracellular domains of TLR1 and TLR2 in NF-kappa B signaling. J Cell Biol 2003; 162: 1099-1110.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 1099-1110
-
-
Sandor, F.1
Latz, E.2
Re, F.3
-
28
-
-
0242391997
-
The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily
-
Heil F, Ahmad-Nejad P, Hemmi H et al. The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily. Eur J Immunol 2003; 33: 2987-2997.
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 2987-2997
-
-
Heil, F.1
Ahmad-Nejad, P.2
Hemmi, H.3
-
29
-
-
10744219675
-
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
-
Latz E, Schoenemeyer A, Visintin A et al. TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat Immunol 2004; 5: 190-198.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 190-198
-
-
Latz, E.1
Schoenemeyer, A.2
Visintin, A.3
-
30
-
-
0037033073
-
Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction
-
Latz E, Visintin A, Lien E et al. Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction. J Biol Chem 2002; 277: 47834-47843.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47834-47843
-
-
Latz, E.1
Visintin, A.2
Lien, E.3
-
31
-
-
0345767207
-
The LPS receptor generates inflammatory signals from the cell surface
-
Latz E, Visintin A, Lien E, Fitzgerald KA, Espevik T, Golenbock DT. The LPS receptor generates inflammatory signals from the cell surface. J Endotoxin Res 2003; 9: 375-380.
-
(2003)
J. Endotoxin. Res.
, vol.9
, pp. 375-380
-
-
Latz, E.1
Visintin, A.2
Lien, E.3
Fitzgerald, K.A.4
Espevik, T.5
Golenbock, D.T.6
-
32
-
-
0036318851
-
Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments
-
Ahmad-Nejad P, Hacker H, Rutz M, Bauer S, Vabulas RM, Wagner H. Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments. Eur J Immunol 2002; 32: 1958-1968.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 1958-1968
-
-
Ahmad-Nejad, P.1
Hacker, H.2
Rutz, M.3
Bauer, S.4
Vabulas, R.M.5
Wagner, H.6
-
33
-
-
0037194733
-
Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane
-
Chow A, Toomre D, Garrett W, Mellman I. Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane. Nature 2002; 418: 988-994.
-
(2002)
Nature
, vol.418
, pp. 988-994
-
-
Chow, A.1
Toomre, D.2
Garrett, W.3
Mellman, I.4
-
34
-
-
0037194784
-
T-cell engagement of dendritic cells rapidly rearranges MHC class II transport
-
Boes M, Cerny J, Massol R et al. T-cell engagement of dendritic cells rapidly rearranges MHC class II transport. Nature 2002; 418: 983-988.
-
(2002)
Nature
, vol.418
, pp. 983-988
-
-
Boes, M.1
Cerny, J.2
Massol, R.3
-
35
-
-
0032476602
-
CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation
-
Hacker H, Mischak H, Miethke T et al. CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation. EMBO J 1998; 17: 6230-6240.
-
(1998)
EMBO J.
, vol.17
, pp. 6230-6240
-
-
Hacker, H.1
Mischak, H.2
Miethke, T.3
-
36
-
-
0035825154
-
The phagosome proteome: Insight into phagosome functions
-
Garin J, Diez R, Kieffer S et al. The phagosome proteome: insight into phagosome functions. J Cell Biol 2001; 152: 165-180.
-
(2001)
J. Cell Biol.
, vol.152
, pp. 165-180
-
-
Garin, J.1
Diez, R.2
Kieffer, S.3
-
37
-
-
0037067649
-
Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages
-
Gagnon E, Duclos S, Rondeau C et al. Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages. Cell 2002; 110: 119-131.
-
(2002)
Cell
, vol.110
, pp. 119-131
-
-
Gagnon, E.1
Duclos, S.2
Rondeau, C.3
-
38
-
-
18344405138
-
Phagosomes are competent organelles for antigen cross-presentation
-
Houde M, Bertholet S, Gagnon E et al. Phagosomes are competent organelles for antigen cross-presentation. Nature 2003; 425: 402-406.
-
(2003)
Nature
, vol.425
, pp. 402-406
-
-
Houde, M.1
Bertholet, S.2
Gagnon, E.3
-
39
-
-
0141707939
-
ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells
-
Guermonprez P, Saveanu L, Kleijmeer M, Davoust J, Van Endert P, Amigorena S. ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells. Nature 2003; 425: 397-402.
-
(2003)
Nature
, vol.425
, pp. 397-402
-
-
Guermonprez, P.1
Saveanu, L.2
Kleijmeer, M.3
Davoust, J.4
Van Endert, P.5
Amigorena, S.6
-
40
-
-
1042290493
-
Recent developments in MHC-class-I-mediated antigen presentation
-
Lehner PJ, Cresswell P. Recent developments in MHC-class-I-mediated antigen presentation. Curr Opin Immunol 2004; 16: 82-89.
-
(2004)
Curr. Opin. Immunol.
, vol.16
, pp. 82-89
-
-
Lehner, P.J.1
Cresswell, P.2
-
41
-
-
3242804567
-
Cellular mechanisms governing cross-presentation of exogenous antigens
-
Ackermann ML, Cresswell P. Cellular mechanisms governing cross-presentation of exogenous antigens. Nat Immunol 2004; 5 678-684.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 678-684
-
-
Ackermann, M.L.1
Cresswell, P.2
-
42
-
-
0035865054
-
Human peripheral blood cells differentially recognize and respond to two distinct CpG motifs
-
Verthelyi D, Ishii KJ, Gursel M, Takeshita F, Klinman DM. Human peripheral blood cells differentially recognize and respond to two distinct CpG motifs. J Immunol 2001; 166: 2372-2377.
-
(2001)
J. Immunol.
, vol.166
, pp. 2372-2377
-
-
Verthelyi, D.1
Ishii, K.J.2
Gursel, M.3
Takeshita, F.4
Klinman, D.M.5
-
43
-
-
0034952872
-
From bugs to drugs: Therapeutic immunomodulation with oligodeoxynucleotides containing CpG sequences from bacterial DNA
-
Krieg AM. From bugs to drugs: therapeutic immunomodulation with oligodeoxynucleotides containing CpG sequences from bacterial DNA. Antisense Nucleic Acid Drug Dev 2001; 11: 181-188.
-
(2001)
Antisense Nucleic Acid Drug Dev.
, vol.11
, pp. 181-188
-
-
Krieg, A.M.1
-
44
-
-
2342558523
-
Antitumor applications of stimulating Toll-like receptor 9 with CpG oligodeoxynucleotides
-
Krieg AM. Antitumor applications of stimulating Toll-like receptor 9 with CpG oligodeoxynucleotides. Curr Oncol Report 2004; 6: 88-95.
-
(2004)
Curr. Oncol. Report
, vol.6
, pp. 88-95
-
-
Krieg, A.M.1
-
45
-
-
3042548161
-
Use of CpG oligodeoxynucleotides as immunoprotective agents
-
Klinman DM. Use of CpG oligodeoxynucleotides as immunoprotective agents. Expert Opin Biol Ther 2004; 4: 937-946.
-
(2004)
Expert Opin. Biol. Ther.
, vol.4
, pp. 937-946
-
-
Klinman, D.M.1
-
46
-
-
1842631153
-
Immunotherapeutic uses of CpG oligodeoxynucleotides
-
Klinman DM. Immunotherapeutic uses of CpG oligodeoxynucleotides. Nat Rev Immunol 2004; 4: 249-258.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 249-258
-
-
Klinman, D.M.1
|