Interferon-α/β receptor-mediated selective induction of a gene cluster by CpG oligodeoxynucleotide 2006

BMC Immunology

Volumn 4, Issue , 2003, Pages

  Kato, Atsushi ^a,b   Homma, Toshiki ^a,b   Batchelor, Jonathan ^c   Hashimoto, Noriko ^a   Imai, Shosuke ^d   Wakiguchi, Hiroshi ^d   Saito, Hirohisa ^a,e   Matsumoto, Kenji ^a,e  

^a NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^b Genox Research Inc   (Japan)

^c NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^d KOCHI MEDICAL SCHOOL   (Japan)

^e RIKEN   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; ALPHA INTERFERON RECEPTOR; BETA INTERFERON RECEPTOR; CHEMOATTRACTANT; CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON RECEPTOR; INTERLEUKIN 6; MESSENGER RNA; MONOCLONAL ANTIBODY; OLIGODEOXYNUCLEOTIDE; UNCLASSIFIED DRUG; VIRUS PROTEIN; ALPHA BETA INTERFERON RECEPTOR; ANTIVIRUS AGENT; CYTOKINE; DNA; INTERFERON; MEMBRANE PROTEIN; OLIGODEOXYRIBONUCLEOTIDE;

ARTICLE; CELL CULTURE; CELLULAR IMMUNITY; CLUSTER ANALYSIS; COMPUTER PROGRAM; CONTROLLED STUDY; CPG ISLAND; GENE CLUSTER; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IN VIVO STUDY; KINETICS; MOLECULAR DYNAMICS; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; PARACRINE SIGNALING; PERIPHERAL BLOOD MONONUCLEAR CELL; PREDICTION; TH1 CELL; TIME; UNINDEXED SEQUENCE; UPREGULATION; VOLUNTEER; DNA MICROARRAY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; MONONUCLEAR CELL; MULTIGENE FAMILY;

ANTIBODIES, MONOCLONAL; ANTIVIRAL AGENTS; CELLS, CULTURED; CYTOKINES; DNA; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; INTERFERON TYPE I; LEUKOCYTES, MONONUCLEAR; MEMBRANE PROTEINS; MULTIGENE FAMILY; OLIGODEOXYRIBONUCLEOTIDES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTOR, INTERFERON ALPHA-BETA; RECEPTORS, INTERFERON; RNA, MESSENGER; UP-REGULATION;

EID: 0642277951     PISSN: 14712172     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2172-4-8     Document Type: Article

References (49)

1. Whittle HC, Lamb WH and Ryder RW: Trials of intradermal hepatitis B vaccines in Gambian children Ann Trop Paediatr 1987, 7:6-9.
2. Uede T, Huff TF and Ishizaka K: Formation of IgE-binding factors by rat T lymphocytes. V. Effect of adjuvant for the priming immunization on the nature of IgE binding factors formed by antigenic stimulation J Immunol 1982, 129:1384-90.
3. Koh YI, Choi IS and Kim WY: BCG infection in allergen-presensitized rats suppresses Th2 immune response and prevents the development of allergic asthmatic reaction J Clin Immunol 2001, 21:51-9.
4. Tokunaga T, Yamamoto T and Yamamoto S: How BCG led to the discovery of immunostimulatory DNA Jpn J Infect Dis 1999, 52:1-11.
5. Tokunaga T, Yamamoto H, Shimada S, Abe H, Fukuda T, Fujisawa Y, Furutani Y, Yano O, Kataoka T and Sudo T et al.: Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. I. Isolation, physicochemical characterization, and antitumor activity J Natl Cancer Inst 1984, 72:955-62.
6. Hartmann G, Weeratna RD, Ballas ZK, Payette P, Blackwell S, Suparto I, Rasmussen WL, Waldschmidt M, Sajuthi D and Purcell RH et al.: Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo J Immunol 2000, 164:1617-24.
7. Medzhitov R and Janeway CA Jr: Innate immunity: the virtues of a nonclonal system of recognition Cell 1997, 91:295-8.
8. Krieg AM: The role of CpG motifs in innate immunity Curr Opin Immunol 2000, 12:35-43.
9. Rock FL, Hardiman G, Timans JC, Kastelein RA and Bazan JF: A family of human receptors structurally related to Drosophila Toll Proc Natl Acad Sci U S A 1998, 95:588-93.
10. Lemaitre B, Nicolas E, Michaut L, Reichhart JM and Hoffmann JA: The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults Cell 1996, 86:973-83.
11. Akira S, Takeda K and Kaisho T: Toll-like receptors: critical proteins linking innate and acquired immunity Nat Immunol 2001, 2:675-80.
12. Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, Sanjo H, Matsumoto M, Hoshino K, Wagner H and Takeda K et al.: A Toll-like receptor recognizes bacterial DNA Nature 2000, 408:740-5.
13. Takeshita F, Leifer CA, Gursel I, Ishii KJ, Takeshita S, Gursel M and Klinman DM: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells J Immunol 2001, 167:3555-8.
14. Krieg AM: CpG motifs in bacterial DNA and their immune effects Annu Rev Immunol 2002, 20:709-60.
15. Krug A, Rothenfusser S, Hornung V, Jahrsdorfer B, Blackwell S, Ballas ZK, Endres S, Krieg AM and Hartmann G: Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells Eur J Immunol 2001, 31:2154-63.
16. Gursel M, Verthelyi D, Gursel I, Ishii KJ and Klinman DM: Differential and competitive activation of human immune cells by distinct classes of CpG oligodeoxynucleotide J Leukoc Biol 2002, 71:813-20.
17. Zdilar D, Franco-Bronson K, Buchler N, Locala JA and Younossi ZM: Hepatitis C, interferon alfa, and depression Hepatology 2000, 31:1207-11.
18. Der SD, Zhou A, Williams BR and Silverman RH: Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays Proc Natl Acad Sci U S A 1998, 95:15623-8.
19. Hornung V, Rothenfusser S, Britsch S, Krug A, Jahrsdorfer B, Giese T, Endres S and Hartmann G: Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides J Immunol 2002, 168:4531-7.
20. Blackwell SE and Krieg AM: CpG-A-Induced Monocyte IFN-gamma-Inducible Protein-10 Production Is Regulated by Plasmacytoid Dendritic Cell-Derived IFN-alpha J Immunol 2003, 170:4061-8.
21. Munoz C, Pascual-Salcedo D, Castellanos MC, Alfranca A, Aragones J, Vara A, Redondo MJ and de Landazuri MO: Pyrrolidine dithiocarbamate inhibits the production of interleukin-6, interleukin-8, and granulocyte-macrophage colony-stimulating factor by human endothelial cells in response to inflammatory mediators: modulation of NF-kappa B and AP-1 transcription factors activity Blood 1996, 88:3482-90.
22. Ohshima Y, Yang LP, Avice MN, Kurimoto M, Nakajima T, Sergerie M, Demeure CE, Sarfati M and Delespesse G: Naive human CD4+ T cells are a major source of lymphotoxin alpha J Immunol 1999, 162:3790-4.
23. Shan X, Bourdeau A, Rhoton A, Wells DE, Cohen EH, Landgraf BE and Palfree RG: Characterization and mapping to human chromosome 8q24.3 of Ly-6-related gene 9804 encoding an apparent homologue of mouse TSA-1 J Immunol 1998, 160:197-208.
24. Grotzinger T, Jensen K and Will H: The interferon (IFN)-stimulated gene Sp100 promoter contains an IFN-gamma activation site and an imperfect IFN-stimulated response element which mediate type I IFN inducibility J Biol Chem 1996, 271:25253-60.
25. Sciavolino PJ and Vilcek J: Regulation of metallothionein gene expression by TNF-alpha and IFN-beta in human fibroblasts Cytokine 1995, 7:242-50.
26. Silverman RH, Halloum A, Zhou A, Dong B, Al-Zoghaibi F, Kushner D, Zhou Q, Zhao J, Wiedmer T and Sims PJ: Suppression of ovarian carcinoma cell growth in vivo by the interferon-inducible plasma membrane protein, phospholipid scramblase 1 Cancer Res 2002, 62:397-402.
27. Sedger LM, Shows DM, Blanton RA, Peschon JJ, Goodwin RG, Cosman D and Wiley SR: IFN-gamma mediates a novel antiviral activity through dynamic modulation of TRAIL and TRAIL receptor expression J Immunol 1999, 163:920-6.
28. Kayagaki N, Yamaguchi N, Nakayama M, Eto H, Okumura K and Yagita H: Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs J Exp Med 1999, 189:1451-60
29. Brinkmann V, Geiger T, Alkan S and Heusser CH: Interferon alpha increases the frequency of interferon gamma-producing human CD4+ T cells J Exp Med 1993, 178:1655-63.
30. Hunter CA, Gabriel KE, Radzanowski T, Neyer LE and Remington JS: Type I interferons enhance production of IFN-gamma by NK cells Immunol Lett 1997, 59:1-5.
31. Sato M, Suemori H, Hata N, Asagiri M, Ogasawara K, Nakao K, Nakaya T, Katsuki M, Noguchi S and Tanaka N et al.: Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction Immunity 2000, 13:539-48.
32. Le Bon A and Tough DF: Links between innate and adaptive immunity via type I interferon Curr Opin Immunol 2002, 14:432-6.
33. Siegal FP, Kadowaki N, Shodell M, Fitzgerald-Bocarsly PA, Shah K, Ho S, Antonenko S and Liu YJ: The nature of the principal type 1 interferon-producing cells in human blood Science 1999, 284:1835-7.
34. Cella M, Jarrossay D, Facchetti F, Alebardi O, Nakajima H, Lanzavecchia A and Colonna M: Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon Nat Med 1999, 5:919-23.
35. Kerkmann M, Rothenfusser S, Hornung V, Towarowski A, Wagner M, Sarris A, Giese T, Endres S and Hartmann G: Activation with CpG-A and CpG-B Oligonucleotides Reveals Two Distinct Regulatory Pathways of Type I IFN Synthesis in Human Plasmacytoid Dendritic Cells J Immunol 2003, 170:4465-74.
36. Krieg AM: From A to Z on CpG Trends Immunol 2002, 23:64-5.
37. Guo J, Hui DJ, Merrick WC and Sen GC: A new pathway of translational regulation mediated by eukaryotic initiation factor 3 Embo J 2000, 19:6891-9.
38. Diaz-Guerra M, Rivas C and Esteban M: Inducible expression of the 2-5A synthetase/RNase L system results in inhibition of vaccinia virus replication Virology 1997, 227:220-8.
39. Ponten A, Sick C, Weeber M, Haller O and Kochs G: Dominant-negative mutants of human MxA protein: domains in the carboxy-terminal moiety are important for oligomerization and antiviral activity J Virol 1997, 71:2591-9.
40. Malakhov MP, Malakhova OA, Kim KI, Ritchie KJ and Zhang DE: UBP43 (USP18) specifically removes ISG15 from conjugated proteins J Biol Chem 2002, 277:9976-81.
41. Park Y, Chang YS, Lee SW, Cho SY, Kim YK, Min KU, Kim YY, Cho SH and Sung YC: The enhanced effect of a hexameric deoxyriboguanosine run conjugation to CpG oligodeoxynucleotides on protection against allergic asthma J Allergy Clin Immunol 2001, 108:570-6.
42. Marshall JD, Abtahi S, Eiden JJ, Tuck S, Milley R, Haycock F, Reid MJ, Kagey-Sobotka A, Creticos PS and Lichtenstein LM et al.: Immunostimulatory sequence DNA linked to the Amb a 1 allergen promotes T(H)1 cytokine expression while downregulating T(H)2 cytokine expression in PBMCs from human patients with ragweed allergy J Allergy Clin Immunol 2001, 108:191-7.
43. Shirota H, Sano K, Hirasawa N, Terui T, Ohuchi K, Hattori T and Tamura G: B cells capturing antigen conjugated with CpG oligodeoxynucleotides induce Th1 cells by elaborating IL-12 J Immunol 2002, 169:787-94.
44. Santeliz JV, Van Nest G, Traquina P, Larsen E and Wills-Karp M: Amb a 1-linked CpG oligodeoxynucleotides reverse established airway hyperresponsiveness in a murine model of asthma J Allergy Clin Immunol 2002, 109:455-62.
45. Farrar JD and Murphy KM: Type I interferons and T helper development Immunol Today 2000, 21:484-9.
46. Krug A, Towarowski A, Britsch S, Rothenfusser S, Hornung V, Bals R, Giese T, Engelmann H, Endres S and Krieg AM et al.: Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12 Eur J Immunol 2001, 31:3026-37.
47. Loetscher M, Loetscher P, Brass N, Meese E and Moser B: Lymphocyte-specific chemokine receptor CXCR3: regulation, chemokine binding and gene localization Eur J Immunol 1998, 28:3696-705.
48. Weng Y, Siciliano SJ, Waldburger KE, Sirotina-Meisher A, Staruch MJ, Daugherty BL, Gould SL, Springer MS and DeMartino JA: Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors J Biol Chem 1998, 273:18288-91.
49. Loetscher P, Pellegrino A, Gong JH, Mattioli I, Loetscher M, Bardi G, Baggiolini M and Clark-Lewis I: The ligands of CXC chemokine receptor 3, I-TAC, Mig, and IP10, are natural antagonists for CCR3 J Biol Chem 2001, 276:2986-91.