메뉴 건너뛰기




Volumn 88, Issue 9, 1996, Pages 3482-3490

Pyrrolidine dithiocarbamate inhibits the production of interleukin-6, interleukin-8, and granulocyte-macrophage colony-stimulating factor by human endothelial cells in response to inflammatory mediators: Modulation of NF- κB and AP-1 transcription factors activity

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; BACTERIUM LIPOPOLYSACCHARIDE; DITHIOCARBAMIC ACID DERIVATIVE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; PYRROLIDINE DERIVATIVE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

EID: 0029959753     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.9.3482.bloodjournal8893482     Document Type: Article
Times cited : (162)

References (48)
  • 1
    • 0026725537 scopus 로고
    • Cytokine regulation of endothelial cell function
    • Mantovani A, Bussolino F, Dejana E: Cytokine regulation of endothelial cell function. FASEB J 6:2591, 1992
    • (1992) FASEB J , vol.6 , pp. 2591
    • Mantovani, A.1    Bussolino, F.2    Dejana, E.3
  • 2
    • 0027935309 scopus 로고
    • Leukocyte-endothelial adhesion molecules
    • Carlos TM, Harlan JM: Leukocyte-endothelial adhesion molecules. Blood 7:2068, 1994
    • (1994) Blood , vol.7 , pp. 2068
    • Carlos, T.M.1    Harlan, J.M.2
  • 3
    • 0028557450 scopus 로고
    • Chemokines, leukocyte trafficking, and inflammation
    • Schall TJ, Bacon KB: Chemokines, leukocyte trafficking, and inflammation. Curr Opin Immunol 6:865, 1994
    • (1994) Curr Opin Immunol , vol.6 , pp. 865
    • Schall, T.J.1    Bacon, K.B.2
  • 4
    • 0023152506 scopus 로고
    • Chemotactic activity of human recombinant granulocyte-macrophage colony-stimulating factor
    • Wang JM, Colella S, Allavena P, Mantovani A: Chemotactic activity of human recombinant granulocyte-macrophage colony-stimulating factor. Immunology 60:439, 1987
    • (1987) Immunology , vol.60 , pp. 439
    • Wang, J.M.1    Colella, S.2    Allavena, P.3    Mantovani, A.4
  • 5
    • 0023783962 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor induces the expression of the CDI 1b surface adhesion molecule on human granulocytes in vivo
    • Socinski MA, Cannistra SA, Sullivan R, Elias A, Antman K, Schnipper L, Griffins JD: Granulocyte-macrophage colony-stimulating factor induces the expression of the CDI 1b surface adhesion molecule on human granulocytes in vivo. Blood 72:691, 1988
    • (1988) Blood , vol.72 , pp. 691
    • Socinski, M.A.1    Cannistra, S.A.2    Sullivan, R.3    Elias, A.4    Antman, K.5    Schnipper, L.6    Griffins, J.D.7
  • 6
    • 0027365599 scopus 로고
    • Vascular adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells
    • Marui N, Offermann MK, Swerlick R, Kunsch C, Rosen CA, Ahmad M, Alexander RW, Medford RM: Vascular adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J Clin Invest 92:1866, 1993
    • (1993) J Clin Invest , vol.92 , pp. 1866
    • Marui, N.1    Offermann, M.K.2    Swerlick, R.3    Kunsch, C.4    Rosen, C.A.5    Ahmad, M.6    Alexander, R.W.7    Medford, R.M.8
  • 7
    • 0028148369 scopus 로고
    • Antioxidants inhibit monocyte adhesion by suppressing nuclear factor-κB mobilization and induction of vascular adhesion molecule-1 in human endothelial cells stimulated to generate radicals
    • Weber C, Erl W, Pietsch A, Ströbel M, Lörns Ziegler-Heitbrock HW, Weber PC: Antioxidants inhibit monocyte adhesion by suppressing nuclear factor-κB mobilization and induction of vascular adhesion molecule-1 in human endothelial cells stimulated to generate radicals. Arterioscler Thromb 14:1665, 1994
    • (1994) Arterioscler Thromb , vol.14 , pp. 1665
    • Weber, C.1    Erl, W.2    Pietsch, A.3    Ströbel, M.4    Lörns Ziegler-Heitbrock, H.W.5    Weber, P.C.6
  • 8
    • 0029063964 scopus 로고
    • Pyrrolidine dithiocarbamate abrogates tissue factor (TF) expression by endothelial cells: Evidence implicating nuclear factor-κB in TF induction by diverse agonists
    • Orthner CL, Rodgers GM, Fitgerald LA: Pyrrolidine dithiocarbamate abrogates tissue factor (TF) expression by endothelial cells: Evidence implicating nuclear factor-κB in TF induction by diverse agonists. Blood 86:436, 1995
    • (1995) Blood , vol.86 , pp. 436
    • Orthner, C.L.1    Rodgers, G.M.2    Fitgerald, L.A.3
  • 10
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • Baeuerle PA, Henkel T: Function and activation of NF-κB in the immune system. Annu Rev Immunol 12:141, 1994
    • (1994) Annu Rev Immunol , vol.12 , pp. 141
    • Baeuerle, P.A.1    Henkel, T.2
  • 11
    • 0026590541 scopus 로고
    • Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells
    • Scherck R, Meier B. Männel DN, Dröge W, Baeuerle P: Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells. J Exp Med 175:1181, 1992
    • (1992) J Exp Med , vol.175 , pp. 1181
    • Scherck, R.1    Meier, B.2    Männel, D.N.3    Dröge, W.4    Baeuerle, P.5
  • 12
    • 0025077481 scopus 로고
    • Redox regulation of Fos and Jun DNA-binding activity in vitro
    • Abate C, Patel L, Rauscher FJ III, Curran T: Redox regulation of Fos and Jun DNA-binding activity in vitro. Science 249:1157, 1990
    • (1990) Science , vol.249 , pp. 1157
    • Abate, C.1    Patel, L.2    Rauscher III, F.J.3    Curran, T.4
  • 13
    • 0027269781 scopus 로고
    • 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor
    • 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J 12:2005, 1993
    • (1993) EMBO J , vol.12 , pp. 2005
    • Meyer, M.1    Schreck, R.2    Baeuerle, P.A.3
  • 14
    • 0025138248 scopus 로고
    • Involvement of a NF-κB-like transcription factor in the activation of the interleukin-6 gene by inflammatory lymphokines
    • Shimizu H, Mitomo K, Watanabe T, Okamoto S, Yamamoto K: Involvement of a NF-κB-like transcription factor in the activation of the interleukin-6 gene by inflammatory lymphokines. Mol Cell Biol 10:561, 1990
    • (1990) Mol Cell Biol , vol.10 , pp. 561
    • Shimizu, H.1    Mitomo, K.2    Watanabe, T.3    Okamoto, S.4    Yamamoto, K.5
  • 15
    • 0025280023 scopus 로고
    • Interleukin-6 induction by tumor necrosis factor and interleukin-1 in human fibroblasts involves activation of a nuclear factor binding to a κB-like sequence
    • Zhang Y, Lin J-X, Vilcek J: Interleukin-6 induction by tumor necrosis factor and interleukin-1 in human fibroblasts involves activation of a nuclear factor binding to a κB-like sequence. Mol Cell Biol 10:3818, 1990
    • (1990) Mol Cell Biol , vol.10 , pp. 3818
    • Zhang, Y.1    Lin, J.-X.2    Vilcek, J.3
  • 16
    • 0025343895 scopus 로고
    • Activation of interleukin-6 gene expression through the NF-κB transcription factor
    • Libermann TA, Baltimore D: Activation of interleukin-6 gene expression through the NF-κB transcription factor. Mol Cell Biol 10:2327, 1990
    • (1990) Mol Cell Biol , vol.10 , pp. 2327
    • Libermann, T.A.1    Baltimore, D.2
  • 17
    • 0025601628 scopus 로고
    • Cooperative interaction of nuclear factor-κB and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines
    • Mukaida N, Mahe Y, Matsushima K: Cooperative interaction of nuclear factor-κB and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines. J Biol Chem 265:21128, 1990
    • (1990) J Biol Chem , vol.265 , pp. 21128
    • Mukaida, N.1    Mahe, Y.2    Matsushima, K.3
  • 18
    • 0027379055 scopus 로고
    • Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-κB
    • Stein B, Baldwin AS: Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-κB. Mol Cell Biol 13:7191, 1993
    • (1993) Mol Cell Biol , vol.13 , pp. 7191
    • Stein, B.1    Baldwin, A.S.2
  • 19
    • 0025139463 scopus 로고
    • NF-κB as inducible transcriptional activator of the granulocyte-macrophage colony-stimulating factor
    • Schreck R, Baeuerle PA: NF-κB as inducible transcriptional activator of the granulocyte-macrophage colony-stimulating factor. Mol Cell Biol 10:1281, 1990
    • (1990) Mol Cell Biol , vol.10 , pp. 1281
    • Schreck, R.1    Baeuerle, P.A.2
  • 21
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    • Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ: Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294, 1979
    • (1979) Biochemistry , vol.18 , pp. 5294
    • Chirgwin, J.M.1    Przybyla, A.E.2    MacDonald, R.J.3    Rutter, W.J.4
  • 23
    • 0342742310 scopus 로고
    • Tumor necrosis factor α and interleukin 1 stimulate the immunodeficiency virus enhancer by active nuclear factor κB
    • Osborn L, Kunkel S, Nabel GJ: Tumor necrosis factor α and interleukin 1 stimulate the immunodeficiency virus enhancer by active nuclear factor κB. Proc Natl Acad Sci USA 86:2336, 1989
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2336
    • Osborn, L.1    Kunkel, S.2    Nabel, G.J.3
  • 24
    • 0025941557 scopus 로고
    • Identification of an essential site for transcriptional activation within the human T-cell receptor δ enhancer
    • Redondo JM, Pfhol JL, Krangel MS: Identification of an essential site for transcriptional activation within the human T-cell receptor δ enhancer. Mol Cell Biol 11:5671, 1991
    • (1991) Mol Cell Biol , vol.11 , pp. 5671
    • Redondo, J.M.1    Pfhol, J.L.2    Krangel, M.S.3
  • 25
  • 28
    • 0027965614 scopus 로고
    • Transcriptional inhibition of the interleukin-8 gene by interferon is mediated by the NF-κB site
    • Oliveira IC, Mukaida N, Matsushima K, Vilcek J: Transcriptional inhibition of the interleukin-8 gene by interferon is mediated by the NF-κB site. Mol Cell Biol 14:5300, 1994
    • (1994) Mol Cell Biol , vol.14 , pp. 5300
    • Oliveira, I.C.1    Mukaida, N.2    Matsushima, K.3    Vilcek, J.4
  • 29
    • 0028176449 scopus 로고
    • The interleukin-8 AP-1 and κB-like sites are genetic end targets of FK506-sensitive pathway accompanied by calcium mobilization
    • Okamoto S, Mukaida N, Yasumoto K, Rice N, Ishikawa Y, Horiguchi H, Murakami S, Matsushima K: The interleukin-8 AP-1 and κB-like sites are genetic end targets of FK506-sensitive pathway accompanied by calcium mobilization. J Biol Chem 269:8582, 1994
    • (1994) J Biol Chem , vol.269 , pp. 8582
    • Okamoto, S.1    Mukaida, N.2    Yasumoto, K.3    Rice, N.4    Ishikawa, Y.5    Horiguchi, H.6    Murakami, S.7    Matsushima, K.8
  • 30
    • 0029147741 scopus 로고
    • Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-κB and C/EBPβ
    • Stein B, Yang MX: Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-κB and C/EBPβ. Mol Cell Biol 15:4971, 1995
    • (1995) Mol Cell Biol , vol.15 , pp. 4971
    • Stein, B.1    Yang, M.X.2
  • 31
    • 0027453552 scopus 로고
    • Transcription factors NF-IL6 and NF-κB synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8
    • Matsusaka T, Fujikawa K, Nishio Y, Mukaida N, Matsushima K, Kishimoto T, Akira S: Transcription factors NF-IL6 and NF-κB synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8. Proc Natl Acad Sci USA 90:10197, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10197
    • Matsusaka, T.1    Fujikawa, K.2    Nishio, Y.3    Mukaida, N.4    Matsushima, K.5    Kishimoto, T.6    Akira, S.7
  • 32
    • 0028359534 scopus 로고
    • Calcineurin activates transcription from the GM-CSF promoter in synergy with either protein kinase C or NF-κB/AP-1 in T cells
    • Tsuboi A, Muramatsu A, Tsutsumi A, Arai K, Arai N: Calcineurin activates transcription from the GM-CSF promoter in synergy with either protein kinase C or NF-κB/AP-1 in T cells. Biochem Biophys Res Commun 199:1064, 1994
    • (1994) Biochem Biophys Res Commun , vol.199 , pp. 1064
    • Tsuboi, A.1    Muramatsu, A.2    Tsutsumi, A.3    Arai, K.4    Arai, N.5
  • 33
    • 0027434124 scopus 로고
    • HTLV-1 tax activation of the GM-CSF and G-CSF promoters requires the interaction of NF-kappa B with other transcription factor families
    • Himes SR, Coles LS, Katsikeros, Lang RK, Shannon MF: HTLV-1 tax activation of the GM-CSF and G-CSF promoters requires the interaction of NF-kappa B with other transcription factor families. Oncogene 8:3189, 1993
    • (1993) Oncogene , vol.8 , pp. 3189
    • Himes, S.R.1    Coles, L.S.2    Katsikeros3    Lang, R.K.4    Shannon, M.F.5
  • 34
    • 0028055284 scopus 로고
    • Activation of the granuloyte-macrophage colony-stimulating factor promoter in T cells requires cooperative binding of Elf-1 and AP-1 transcription factors
    • Wang CY, Bassuk AG, Boise LH, Thompson CB, Bravo R, Leiden JM: Activation of the granuloyte-macrophage colony-stimulating factor promoter in T cells requires cooperative binding of Elf-1 and AP-1 transcription factors. Mol Cell Biol 14:1153, 1994
    • (1994) Mol Cell Biol , vol.14 , pp. 1153
    • Wang, C.Y.1    Bassuk, A.G.2    Boise, L.H.3    Thompson, C.B.4    Bravo, R.5    Leiden, J.M.6
  • 35
    • 0025720735 scopus 로고
    • The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
    • Angel P, Karin M: The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta 1072:129, 1991
    • (1991) Biochim Biophys Acta , vol.1072 , pp. 129
    • Angel, P.1    Karin, M.2
  • 36
    • 0029032249 scopus 로고
    • The regulation of AP-1 activity by mitogen-activated protein kinases
    • Karin M: The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 270:16483, 1995
    • (1995) J Biol Chem , vol.270 , pp. 16483
    • Karin, M.1
  • 37
    • 0028969349 scopus 로고
    • New concepts in the immunopathogenesis of HIV infection
    • Fauci AS, Pantaleo G: New concepts in the immunopathogenesis of HIV infection. Annu Rev Immunol 13:487, 1995
    • (1995) Annu Rev Immunol , vol.13 , pp. 487
    • Fauci, A.S.1    Pantaleo, G.2
  • 39
    • 0028148227 scopus 로고
    • A proteasome inhibitor prevents activation of NF-κB and stabilizes a newly phosphorylated form of IκB-α that is still bound to NF-κB
    • Praenckner EB, Wilk S, Baeuerle PA: A proteasome inhibitor prevents activation of NF-κB and stabilizes a newly phosphorylated form of IκB-α that is still bound to NF-κB. EMBO J 13:5433, 1994
    • (1994) EMBO J , vol.13 , pp. 5433
    • Praenckner, E.B.1    Wilk, S.2    Baeuerle, P.A.3
  • 40
    • 0028978032 scopus 로고
    • Phosphorylation of human IκB-α on serines 32 and 36 controls IκB-α proteolysis and NF-κB activation in response to diverse stimuli
    • Praenckner EB, Pahl HL, Henkel T, Schmidt KN, Wilk S, Baeuerle PA: Phosphorylation of human IκB-α on serines 32 and 36 controls IκB-α proteolysis and NF-κB activation in response to diverse stimuli. EMBO J 14:2876, 1995
    • (1995) EMBO J , vol.14 , pp. 2876
    • Praenckner, E.B.1    Pahl, H.L.2    Henkel, T.3    Schmidt, K.N.4    Wilk, S.5    Baeuerle, P.A.6
  • 41
    • 0028557348 scopus 로고
    • Tumor necrosis factor α-induced phosphorylation of IκB-α is a signal for its degradation but not dissociation from NF-κB
    • Miyamato S, Maki M, Schmitt MJ, Hatanaka M, Verma IM: Tumor necrosis factor α-induced phosphorylation of IκB-α is a signal for its degradation but not dissociation from NF-κB. Proc Natl Acad Sci USA 91:12740, 1994
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12740
    • Miyamato, S.1    Maki, M.2    Schmitt, M.J.3    Hatanaka, M.4    Verma, I.M.5
  • 42
    • 0028172869 scopus 로고
    • Inducible phosphorylation of IκB-α is not sufficient for its dissociation from NF-κB and is inhibited by protease inhibitors
    • Finco TS, Beg AA, Baldwin AS: Inducible phosphorylation of IκB-α is not sufficient for its dissociation from NF-κB and is inhibited by protease inhibitors. Proc Natl Acad Sci USA 91:11884, 1994
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11884
    • Finco, T.S.1    Beg, A.A.2    Baldwin, A.S.3
  • 43
    • 0029091013 scopus 로고
    • Selective inhibition of E-selectin, vascular cell adhesion molecule-1, an intercellular adhesion molecule-1 expression by inhibitors of IκB-α phosphorylation
    • Chen CC, Rosenbloom CI, Anderson DC, Manning AM: Selective inhibition of E-selectin, vascular cell adhesion molecule-1, an intercellular adhesion molecule-1 expression by inhibitors of IκB-α phosphorylation. J Immunol 155:3538, 1995
    • (1995) J Immunol , vol.155 , pp. 3538
    • Chen, C.C.1    Rosenbloom, C.I.2    Anderson, D.C.3    Manning, A.M.4
  • 44
    • 0029010658 scopus 로고
    • The proteasome pathway is required for cytokine-induced endothelial leukocyte adhesion molecule expression
    • Read MA, Neish AS, Luscinskas FW, Palombella VJ, Maniatis T, Collins T: The proteasome pathway is required for cytokine-induced endothelial leukocyte adhesion molecule expression. Immunity 2:493, 1995
    • (1995) Immunity , vol.2 , pp. 493
    • Read, M.A.1    Neish, A.S.2    Luscinskas, F.W.3    Palombella, V.J.4    Maniatis, T.5    Collins, T.6
  • 46
    • 0028099150 scopus 로고
    • Signal transduction for nuclear factor-κB activation
    • Suzuki YJ, Mitzuno M, Packer L: Signal transduction for nuclear factor-κB activation. J Immunol 153:5008, 1994
    • (1994) J Immunol , vol.153 , pp. 5008
    • Suzuki, Y.J.1    Mitzuno, M.2    Packer, L.3
  • 47
    • 0026755187 scopus 로고
    • Regulation of human NAD(P)H:quinone oxidoreductase gene
    • Li Y, Jaiswal AK: Regulation of human NAD(P)H:quinone oxidoreductase gene. J Biol Chem 267:15097, 1992
    • (1992) J Biol Chem , vol.267 , pp. 15097
    • Li, Y.1    Jaiswal, A.K.2
  • 48
    • 0028009237 scopus 로고
    • Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region
    • Hsu W, Kerppola TK, Chen P, Curran T, Chen-Kiang S: Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region. Mol Cell Biol 14:268, 1994
    • (1994) Mol Cell Biol , vol.14 , pp. 268
    • Hsu, W.1    Kerppola, T.K.2    Chen, P.3    Curran, T.4    Chen-Kiang, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.