-
1
-
-
0037055025
-
Antiretroviral treatment for adult HIV infection in 2002: Updated recommendations of the International AIDS Society-USA Panel
-
Yeni PG, Hammer SM, Carpenter CC, Cooper DA, Fischl MA, Gatell JM, Gazzard BG, Hirsch MS, Jacobsen DM, Katzenstein DA, Montaner JS, Richman DD, Saag MS, Schechter M, Schooley RT, Thompson MA, Vella S & Volberding PA. Antiretroviral treatment for adult HIV infection in 2002: updated recommendations of the International AIDS Society-USA Panel. Journal of the American Medical Association 2002; 288:222-235.
-
(2002)
Journal of the American Medical Association
, vol.288
, pp. 222-235
-
-
Yeni, P.G.1
Hammer, S.M.2
Carpenter, C.C.3
Cooper, D.A.4
Fischl, M.A.5
Gatell, J.M.6
Gazzard, B.G.7
Hirsch, M.S.8
Jacobsen, D.M.9
Katzenstein, D.A.10
Montaner, J.S.11
Richman, D.D.12
Saag, M.S.13
Schechter, M.14
Schooley, R.T.15
Thompson, M.A.16
Vella, S.17
Volberding, P.A.18
-
2
-
-
0038234808
-
Antiretroviral drug resistance testing in adults infected with human immunodeficiency virus type 1: 2003 Recommendations of an International AIDS Society-USA Panel
-
Hirsch MS, Brun-Vezinet F, Clotet B, Conway B, Kuritzkes DR, D'Aquila RT, Demeter LM, Hammer SM, Johnson VA, Loveday C, Mellors JW, Jacobsen DM & Richman DD. Antiretroviral drug resistance testing in adults infected with human immunodeficiency virus type 1: 2003 recommendations of an International AIDS Society-USA Panel. Clinical Infectious Diseases 2003; 37:113-128.
-
(2003)
Clinical Infectious Diseases
, vol.37
, pp. 113-128
-
-
Hirsch, M.S.1
Brun-Vezinet, F.2
Clotet, B.3
Conway, B.4
Kuritzkes, D.R.5
D'Aquila, R.T.6
Demeter, L.M.7
Hammer, S.M.8
Johnson, V.A.9
Loveday, C.10
Mellors, J.W.11
Jacobsen, D.M.12
Richman, D.D.13
-
3
-
-
0033014502
-
HIV resistance to zidovudine: The role of pyrophosphorolysis
-
Arion D & Parniak MA. HIV resistance to zidovudine: the role of pyrophosphorolysis. Drug Resistance Update 1999; 2:91-95.
-
(1999)
Drug Resistance Update
, vol.2
, pp. 91-95
-
-
Arion, D.1
Parniak, M.A.2
-
4
-
-
0034616958
-
The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase
-
Gao H-Q, Boyer PL, Sarafianos SG, Arnold E & Hughes SH. The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase. Journal of Molecular Biology 2000; 300:403-418.
-
(2000)
Journal of Molecular Biology
, vol.300
, pp. 403-418
-
-
Gao, H.-Q.1
Boyer, P.L.2
Sarafianos, S.G.3
Arnold, E.4
Hughes, S.H.5
-
5
-
-
0024310253
-
Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)
-
Larder BA & Kemp SD. Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT). Science 1989; 246:1155-1158.
-
(1989)
Science
, vol.246
, pp. 1155-1158
-
-
Larder, B.A.1
Kemp, S.D.2
-
6
-
-
0346090032
-
In vitro selection of the T251Y and K65R mutations by stavudine and demonstration of high-level resistance to stavudine
-
Abstract 31
-
Garcia-Lerma G, MacInnes H, Nidtha S, Bennet D, Weinstock H & Heneine W. In vitro selection of the T251Y and K65R mutations by stavudine and demonstration of high-level resistance to stavudine. Antiviral Therapy 2002; 7:S28. Abstract 31.
-
(2002)
Antiviral Therapy
, vol.7
-
-
Garcia-Lerma, G.1
MacInnes, H.2
Nidtha, S.3
Bennet, D.4
Weinstock, H.5
Heneine, W.6
-
7
-
-
0000474117
-
Stavudine-based combination and monotherapy selects for zidovudine resistance HIV-1 mutations in zidovudine-naive adults and in paediatric patients
-
Abstract 115
-
Ross L, Danehower S, Johnson M et al. Stavudine-based combination and monotherapy selects for zidovudine resistance HIV-1 mutations in zidovudine-naive adults and in paediatric patients. Antiviral Therapy 1999; 4(Suppl. 1):79. Abstract 115.
-
(1999)
Antiviral Therapy
, vol.4
, Issue.SUPPL. 1
, pp. 79
-
-
Ross, L.1
Danehower, S.2
Johnson, M.3
-
8
-
-
0035159223
-
Thymidine-analog and multi-nucleoside resistance mutations are observed in both zidovudine-naive and zidovudine-experienced subjects with viremia after treatment with stavudine-containing regimens
-
Ross L, Henry K, Paar D, Salvato P, Shaefer M, Fisher R, Liao Q & St Clair M. Thymidine-analog and multi-nucleoside resistance mutations are observed in both zidovudine-naive and zidovudine-experienced subjects with viremia after treatment with stavudine-containing regimens. Journal of Human Virology 2001; 4:217-222.
-
(2001)
Journal of Human Virology
, vol.4
, pp. 217-222
-
-
Ross, L.1
Henry, K.2
Paar, D.3
Salvato, P.4
Shaefer, M.5
Fisher, R.6
Liao, Q.7
St. Clair, M.8
-
9
-
-
0003052774
-
Drug resistance mutations in HIV-1
-
International AIDS Society-USA
-
D'Aquila RT, Schapiro JM, Brun-Vezinet F, Clotet B, Conway B, Demeter LM, Grant RM, Johnson VA, Kuritzkes DR, Loveday C, Shafer RW & Richman DD; International AIDS Society-USA. Drug resistance mutations in HIV-1. Topics in HIV Medicine 2002; 10:11-25.
-
(2002)
Topics in HIV Medicine
, vol.10
, pp. 11-25
-
-
D'Aquila, R.T.1
Schapiro, J.M.2
Brun-Vezinet, F.3
Clotet, B.4
Conway, B.5
Demeter, L.M.6
Grant, R.M.7
Johnson, V.A.8
Kuritzkes, D.R.9
Loveday, C.10
Shafer, R.W.11
Richman, D.D.12
-
10
-
-
0000770125
-
Effects of M41L and T215Y mutations in HIV-1 reverse transcriptase on removal of chain-terminators from blocked primer/templates
-
Abstract 15
-
Meyer PR, Pfeifer I, Matsuura S, Bazmi H, So AG, Mellors JW & Scott WA. Effects of M41L and T215Y mutations in HIV-1 reverse transcriptase on removal of chain-terminators from blocked primer/templates. Antiviral Therapy 2000; 5(Suppl. 3):14. Abstract 15.
-
(2000)
Antiviral Therapy
, vol.5
, Issue.SUPPL. 3
, pp. 14
-
-
Meyer, P.R.1
Pfeifer, I.2
Matsuura, S.3
Bazmi, H.4
So, A.G.5
Mellors, J.W.6
Scott, W.A.7
-
11
-
-
0003284450
-
Determination of a clinically relevant phenotypic resistance 'cutoff' for abacavir using the PhenoSense assay
-
February 4-8; Chicago, Ill., USA. Abstract 254
-
Lanier ER, Hellmann N, Scott J, Ait-Khaled M, Melby T, Paxinos E, Werhane H, Petropoulos C, Kusaba E, St Clair M, Smiley L & Lafon S. Determination of a clinically relevant phenotypic resistance 'cutoff' for abacavir using the PhenoSense assay. Presented at: 8th Conference on Retroviruses & Opportunistic Infections; February 4-8 2001; Chicago, Ill., USA. Abstract 254.
-
(2001)
8th Conference on Retroviruses & Opportunistic Infections
-
-
Lanier, E.R.1
Hellmann, N.2
Scott, J.3
Ait-Khaled, M.4
Melby, T.5
Paxinos, E.6
Werhane, H.7
Petropoulos, C.8
Kusaba, E.9
St. Clair, M.10
Smiley, L.11
Lafon, S.12
-
12
-
-
0003324025
-
Presence of thymidine associated mutations and response to d4T, abacavir and ddI in the control Arm of the Narval ANRS 088 Trial
-
February 4-8; Chicago, Ill., USA. Abstract 450
-
Costagliola D, Descamps D, Calvez V, Masquelier B, Ruffault A, Telles F, Meynard JL & Brun-Vezinet F. Presence of thymidine associated mutations and response to d4T, abacavir and ddI in the control Arm of the Narval ANRS 088 Trial. Presented at: 8th Conference on Retroviruses & Opportunistic Infections; February 4-8, 2001; Chicago, Ill., USA. Abstract 450.
-
(2001)
8th Conference on Retroviruses & Opportunistic Infections
-
-
Costagliola, D.1
Descamps, D.2
Calvez, V.3
Masquelier, B.4
Ruffault, A.5
Telles, F.6
Meynard, J.L.7
Brun-Vezinet, F.8
-
13
-
-
8944256865
-
Drug resistance and virologic response in NUCA 3001, a randomized trial of lamivudine (3TC) versus zidovudine (ZDV) versus ZDV plus 3TC in previously untreated patients
-
Kuritzkes DR, Quinn JB, Benoit SL, Shugarts DL, Griffin A, Bakhtiari M, Poticha D, Eron JJ, Fallon MA & Rubin M. Drug resistance and virologic response in NUCA 3001, a randomized trial of lamivudine (3TC) versus zidovudine (ZDV) versus ZDV plus 3TC in previously untreated patients. AIDS 1996; 10:975-981.
-
(1996)
AIDS
, vol.10
, pp. 975-981
-
-
Kuritzkes, D.R.1
Quinn, J.B.2
Benoit, S.L.3
Shugarts, D.L.4
Griffin, A.5
Bakhtiari, M.6
Poticha, D.7
Eron, J.J.8
Fallon, M.A.9
Rubin, M.10
-
14
-
-
0042276943
-
-
Foster City, Calif., USA: Gilead Sciences, Inc.
-
Emtriva [package insert]. Foster City, Calif., USA: Gilead Sciences, Inc.; 2003.
-
(2003)
Emtriva [Package Insert]
-
-
-
15
-
-
0034088720
-
Resistance profile of the human immunodeficiency virus type 1 reverse transcriptase inhibitor abacavir (1592U89) after monotherapy and combination therapy
-
CNA2001 Investigative Group
-
Harrigan PR, Stone C, Griffin P, Najera I, Bloor S, Kemp S, Tisdale M & Larder B. Resistance profile of the human immunodeficiency virus type 1 reverse transcriptase inhibitor abacavir (1592U89) after monotherapy and combination therapy. CNA2001 Investigative Group. Journal of Infectious Diseases 2000; 181:912-920.
-
(2000)
Journal of Infectious Diseases
, vol.181
, pp. 912-920
-
-
Harrigan, P.R.1
Stone, C.2
Griffin, P.3
Najera, I.4
Bloor, S.5
Kemp, S.6
Tisdale, M.7
Larder, B.8
-
16
-
-
0030892246
-
Human immunodeficiency virus type 1 reverse transcriptase genotype and drug susceptibility changes in infected individuals receiving dideoxyinosine monotherapy for 1 to 2 years
-
Winters MA, Shafer RW, Jellinger RA, Mamtora G, Gingeras T & Merigan TC. Human immunodeficiency virus type 1 reverse transcriptase genotype and drug susceptibility changes in infected individuals receiving dideoxyinosine monotherapy for 1 to 2 years. Antimicrobial Agents & Chemotherapy 1997; 41:757-762.
-
(1997)
Antimicrobial Agents & Chemotherapy
, vol.41
, pp. 757-762
-
-
Winters, M.A.1
Shafer, R.W.2
Jellinger, R.A.3
Mamtora, G.4
Gingeras, T.5
Merigan, T.C.6
-
17
-
-
7144262385
-
The M184V mutation in HIV-1 reverse transcriptase (RT) conferring lamivudine resistance does not result in broad cross-resistance to nucleoside analogue RT inhibitors
-
Miller V, Sturmer M, Staszewski S, Groschel B, Hertogs K, de Bethune MP, Pauwels R, Harrigan PR, Bloor S, Kemp SD & Larder BA. The M184V mutation in HIV-1 reverse transcriptase (RT) conferring lamivudine resistance does not result in broad cross-resistance to nucleoside analogue RT inhibitors. AIDS 1998; 12:705-712.
-
(1998)
AIDS
, vol.12
, pp. 705-712
-
-
Miller, V.1
Sturmer, M.2
Staszewski, S.3
Groschel, B.4
Hertogs, K.5
De Bethune, M.P.6
Pauwels, R.7
Harrigan, P.R.8
Bloor, S.9
Kemp, S.D.10
Larder, B.A.11
-
18
-
-
0347981395
-
M184V significantly delays the emergence of the T215F/T, D67N, and L210W mutations independently of VRNA and time on therapy
-
October 23-27; Lisbon, Portugal. Abstract 1236
-
Ait-Khaled M, Stone C, Amphlett G, Clotet B, Staszewski S & Katlama C. M184V significantly delays the emergence of the T215F/T, D67N, and L210W mutations independently of VRNA and time on therapy. Presented at: 7th European Conference on Clinical Aspects & Treatment of HIV Infection; October 23-27 1999; Lisbon, Portugal. Abstract 1236.
-
(1999)
7th European Conference on Clinical Aspects & Treatment of HIV Infection
-
-
Ait-Khaled, M.1
Stone, C.2
Amphlett, G.3
Clotet, B.4
Staszewski, S.5
Katlama, C.6
-
19
-
-
0003333653
-
The presence of nucleoside analog mutations (NAMs) is highly correlated with reduced susceptibility to all NRTIs
-
February 24-28, Seattle, Wash., USA. Abstract 569-T
-
Whitcomb JM, Paxinos E, Huang W, Maranta M, Limoli K, Chappey C, Parkin NT, Hellmann NS & Petropoulos CJ. The presence of nucleoside analog mutations (NAMs) is highly correlated with reduced susceptibility to all NRTIs. Presented at: 9th Conference on Retroviruses & Opportunistic Infections; February 24-28 2002, Seattle, Wash., USA. Abstract 569-T.
-
(2002)
9th Conference on Retroviruses & Opportunistic Infections
-
-
Whitcomb, J.M.1
Paxinos, E.2
Huang, W.3
Maranta, M.4
Limoli, K.5
Chappey, C.6
Parkin, N.T.7
Hellmann, N.S.8
Petropoulos, C.J.9
-
20
-
-
0346720613
-
Clinical impact of the M184V mutation on switching to didanosine or maintaining lamivudine treatment in nucleoside-experienced patients
-
Abstract 122
-
Winters MA, Bosch RJ, Albrecht MA & Katzenstein DA, for the ACTG 364 Study Team. Clinical impact of the M184V mutation on switching to didanosine or maintaining lamivudine treatment in nucleoside-experienced patients. Antiviral Therapy 2002; 7:S101. Abstract 122.
-
(2002)
Antiviral Therapy
, vol.7
-
-
Winters, M.A.1
Bosch, R.J.2
Albrecht, M.A.3
Katzenstein, D.A.4
-
21
-
-
0032571378
-
Endogenous reverse transcriptase assays reveal synergy between combinations of the M184V and other drug resistance-conferring mutations in interactions with nucleoside analog triphosphates
-
Quan Y, Gu Z, Li X, Liang C, Parniak MA & Wainberg MA. Endogenous reverse transcriptase assays reveal synergy between combinations of the M184V and other drug resistance-conferring mutations in interactions with nucleoside analog triphosphates. Journal of Molecular Biology 1998; 277:237-247.
-
(1998)
Journal of Molecular Biology
, vol.277
, pp. 237-247
-
-
Quan, Y.1
Gu, Z.2
Li, X.3
Liang, C.4
Parniak, M.A.5
Wainberg, M.A.6
-
22
-
-
0343811737
-
Single- step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC
-
Krebs R, Immendorfer U, Thrall SH, Wohrl BM & Goody RS. Single- step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC. Biochemistry 1997; 36:10292-10300.
-
(1997)
Biochemistry
, vol.36
, pp. 10292-10300
-
-
Krebs, R.1
Immendorfer, U.2
Thrall, S.H.3
Wohrl, B.M.4
Goody, R.S.5
-
23
-
-
0033587620
-
Mechanistic studies examining the efficiency and fidelity of DNA synthesis by the 3TC-resistant mutant (184V) of HIV-1 reverse transcriptase
-
Feng JY & Anderson KS. Mechanistic studies examining the efficiency and fidelity of DNA synthesis by the 3TC-resistant mutant (184V) of HIV-1 reverse transcriptase. Biochemistry 1999; 38:9440-9448.
-
(1999)
Biochemistry
, vol.38
, pp. 9440-9448
-
-
Feng, J.Y.1
Anderson, K.S.2
-
24
-
-
0033621167
-
Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with b-branched amino acids
-
Sarafianos SG, Das K, Clark AD Jr, Ding J, Boyer PL, Hughes SH & Arnold E. Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with b-branched amino acids. Proceedings of the National Academy of Sciences, USA 1999; 96:10027-10032.
-
(1999)
Proceedings of the National Academy of Sciences, USA
, vol.96
, pp. 10027-10032
-
-
Sarafianos, S.G.1
Das, K.2
Clark Jr., A.D.3
Ding, J.4
Boyer, P.L.5
Hughes, S.H.6
Arnold, E.7
-
25
-
-
0029896847
-
Endogenous reverse transcription assays reveal high-level resistance to the triphosphate of (-)2′-dideoxy-3′-thiacytidine by mutated M184V human immunodeficiency virus type 1
-
Quan Y, Gu Z, Li X, Li Z, Morrow CD & Wainberg MA. Endogenous reverse transcription assays reveal high-level resistance to the triphosphate of (-)2′-dideoxy-3′-thiacytidine by mutated M184V human immunodeficiency virus type 1. Journal of Virology 1996; 70:5642-5645.
-
(1996)
Journal of Virology
, vol.70
, pp. 5642-5645
-
-
Quan, Y.1
Gu, Z.2
Li, X.3
Li, Z.4
Morrow, C.D.5
Wainberg, M.A.6
-
26
-
-
0030772853
-
Higher fidelity of RNA-dependent DNA mispair extension by M184V drug-resistant than wild-type reverse transcriptase of human immunodeficiency virus type 1
-
Hsu M, Inouye P, Rezende L, Richard N, Li Z, Prasad VR & Wainberg MA. Higher fidelity of RNA-dependent DNA mispair extension by M184V drug-resistant than wild-type reverse transcriptase of human immunodeficiency virus type 1. Nucleic Acids Research 1997; 25:4532-4536.
-
(1997)
Nucleic Acids Research
, vol.25
, pp. 4532-4536
-
-
Hsu, M.1
Inouye, P.2
Rezende, L.3
Richard, N.4
Li, Z.5
Prasad, V.R.6
Wainberg, M.A.7
-
27
-
-
0030791104
-
Increased polymerase fidelity of the 3TC-resistant variants of HIV-1 reverse transcriptase
-
Oude Essink BB, Back NKT & Berkhout B. Increased polymerase fidelity of the 3TC-resistant variants of HIV-1 reverse transcriptase. Nucleic Acids Research 1997; 25:3212-3217.
-
(1997)
Nucleic Acids Research
, vol.25
, pp. 3212-3217
-
-
Oude Essink, B.B.1
Back, N.K.T.2
Berkhout, B.3
-
28
-
-
13344294407
-
Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase
-
Wainberg MA, Drosopoulos WC, Salomon H, Hsu M, Borkow G, Parniak M, Gu Z, Song Q, Manne J, Islam S, Castriota G & Prasad VR. Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase. Science 1996; 271:1282-1285.
-
(1996)
Science
, vol.271
, pp. 1282-1285
-
-
Wainberg, M.A.1
Drosopoulos, W.C.2
Salomon, H.3
Hsu, M.4
Borkow, G.5
Parniak, M.6
Gu, Z.7
Song, Q.8
Manne, J.9
Islam, S.10
Castriota, G.11
Prasad, V.R.12
-
29
-
-
0029035638
-
Analysis of mutations at position 184 in reverse transcriptase of human immunodeficiency virus type 1
-
Boyer PL & Huges SH. Analysis of mutations at position 184 in reverse transcriptase of human immunodeficiency virus type 1. Antimicrobial Agents & Chemotherapy 1995; 39:1624-1628.
-
(1995)
Antimicrobial Agents & Chemotherapy
, vol.39
, pp. 1624-1628
-
-
Boyer, P.L.1
Huges, S.H.2
-
30
-
-
0030691001
-
Limiting deoxynucleoside triphosphate concentrations emphasize the processivity defect of lamivudine-resistant variants of human immunodeficiency virus type 1 reverse transcriptase
-
Back NK & Berkhout B. Limiting deoxynucleoside triphosphate concentrations emphasize the processivity defect of lamivudine-resistant variants of human immunodeficiency virus type 1 reverse transcriptase. Antimicrobial Agents & Chemotherapy 1997; 41:2484-2491.
-
(1997)
Antimicrobial Agents & Chemotherapy
, vol.41
, pp. 2484-2491
-
-
Back, N.K.1
Berkhout, B.2
-
31
-
-
0036149707
-
Persistence and fitness of multidrug-resistant human immunodeficiency virus type 1 acquired in primary infection
-
Brenner BG, Routy JP, Petrella M, Moisi D, Oliveira M, Detorio M, Spira B, Essabag V, Conway B, Lalonde R, Sekaly RP & Wainberg MA. Persistence and fitness of multidrug-resistant human immunodeficiency virus type 1 acquired in primary infection. Journal of Virology 2002; 76:1753-1761.
-
(2002)
Journal of Virology
, vol.76
, pp. 1753-1761
-
-
Brenner, B.G.1
Routy, J.P.2
Petrella, M.3
Moisi, D.4
Oliveira, M.5
Detorio, M.6
Spira, B.7
Essabag, V.8
Conway, B.9
Lalonde, R.10
Sekaly, R.P.11
Wainberg, M.A.12
-
32
-
-
0142100752
-
The M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1 impairs rescue of chain-terminated DNA synthesis
-
Götte M, Arion D, Parniak MA & Wainberg MA. The M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1 impairs rescue of chain-terminated DNA synthesis. Journal of Virology 2000; 74:3579-3585.
-
(2000)
Journal of Virology
, vol.74
, pp. 3579-3585
-
-
Götte, M.1
Arion, D.2
Parniak, M.A.3
Wainberg, M.A.4
-
33
-
-
0036124432
-
The M184V mutation reduces the selective excision of zidovudine 5′-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1
-
Boyer PL, Sarafianos SG, Arnold E & Hughes SH. The M184V mutation reduces the selective excision of zidovudine 5′-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1. Journal of Virology 2002; 76:3248-3256.
-
(2002)
Journal of Virology
, vol.76
, pp. 3248-3256
-
-
Boyer, P.L.1
Sarafianos, S.G.2
Arnold, E.3
Hughes, S.H.4
-
34
-
-
0034947293
-
Increased drug susceptibility of HIV-1 reverse transcriptase mutants containing M184V and zidovudine-associated mutations: Analysis of enzyme processivity, chain-terminator removal and viral replication
-
Naeger LK, Margot NA & Miller MD. Increased drug susceptibility of HIV-1 reverse transcriptase mutants containing M184V and zidovudine-associated mutations: analysis of enzyme processivity, chain-terminator removal and viral replication. Antiviral Therapy 2001; 6:115-126.
-
(2001)
Antiviral Therapy
, vol.6
, pp. 115-126
-
-
Naeger, L.K.1
Margot, N.A.2
Miller, M.D.3
-
35
-
-
0003254824
-
Time to appearance of NRTI-associated mutations and response to subsequent therapy for patients on failing ABC/COM
-
February 4-8; Chicago, Ill., USA. Abstract 448
-
Melby T, Tortell S, Thorborn D, Pearce G, Spreen W, Scott J, Madison S, Lafon S & Lanier ER. Time to appearance of NRTI-associated mutations and response to subsequent therapy for patients on failing ABC/COM. Presented at: 8th Conference on Retroviruses & Opportunistic Infections; February 4-8 2001; Chicago, Ill., USA. Abstract 448.
-
(2001)
8th Conference on Retroviruses & Opportunistic Infections
-
-
Melby, T.1
Tortell, S.2
Thorborn, D.3
Pearce, G.4
Spreen, W.5
Scott, J.6
Madison, S.7
Lafon, S.8
Lanier, E.R.9
-
36
-
-
0029028067
-
Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy
-
Larder BA, Kemp SD & Harrigan PR. Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy. Science 1995; 269:696-699.
-
(1995)
Science
, vol.269
, pp. 696-699
-
-
Larder, B.A.1
Kemp, S.D.2
Harrigan, P.R.3
-
37
-
-
0032766314
-
Zidovudine resensitization and dual HIV-1 resistance to zidovudine and lamivudine in the delta lamivudine roll-over study
-
Masquelier B, Descamps D, Carriere I, Ferchal F, Collin G, Denayrolles M, Ruffault A, Chanzy B, Izopet J, Buffet-Janvresse C, Schmitt MP, Race E, Fleury HJ, Aboulker JP, Yeni P & Brun-Vezinet F. Zidovudine resensitization and dual HIV-1 resistance to zidovudine and lamivudine in the delta lamivudine roll-over study. Antiviral Therapy 1999; 4:69-77.
-
(1999)
Antiviral Therapy
, vol.4
, pp. 69-77
-
-
Masquelier, B.1
Descamps, D.2
Carriere, I.3
Ferchal, F.4
Collin, G.5
Denayrolles, M.6
Ruffault, A.7
Chanzy, B.8
Izopet, J.9
Buffet-Janvresse, C.10
Schmitt, M.P.11
Race, E.12
Fleury, H.J.13
Aboulker, J.P.14
Yeni, P.15
Brun-Vezinet, F.16
-
38
-
-
0347351149
-
Zidovudine/lamivudine co-resistance is preceded by a transient period of zidovudine hypersensitivity
-
Abstract 30
-
Tian H, Whitcomb JM, Limoli K et al. Zidovudine/lamivudine co-resistance is preceded by a transient period of zidovudine hypersensitivity. Antiviral Therapy 1998; 3(Suppl. 1):22. Abstract 30.
-
(1998)
Antiviral Therapy
, vol.3
, Issue.SUPPL. 1
, pp. 30
-
-
Tian, H.1
Whitcomb, J.M.2
Limoli, K.3
-
39
-
-
20644436472
-
In vitro selection and characterization of HIV-1 with reduced susceptibility to PMPA
-
Wainberg MA, Miller MD, Quan Y, Salomon H, Mulato AS, Lamy PD, Margot NA, Anton KE & Cherrington JM. In vitro selection and characterization of HIV-1 with reduced susceptibility to PMPA. Antiviral Therapy 1999; 4:87-94.
-
(1999)
Antiviral Therapy
, vol.4
, pp. 87-94
-
-
Wainberg, M.A.1
Miller, M.D.2
Quan, Y.3
Salomon, H.4
Mulato, A.S.5
Lamy, P.D.6
Margot, N.A.7
Anton, K.E.8
Cherrington, J.M.9
-
40
-
-
0003317879
-
Final 48-week genotypic and phenotypic analyses of study 907: Tenofovir DF added to stable background regimens
-
February 24-28; Seattle, Wash., USA. Poster 414-W
-
Margot NA, Johnson A, Coakley DF, Cheng AK & Miller MD. Final 48-week genotypic and phenotypic analyses of study 907: tenofovir DF added to stable background regimens. Presented at: 9th Conference on Retroviruses & Opportunistic Infections; February 24-28 2002; Seattle, Wash., USA. Poster 414-W.
-
(2002)
9th Conference on Retroviruses & Opportunistic Infections
-
-
Margot, N.A.1
Johnson, A.2
Coakley, D.F.3
Cheng, A.K.4
Miller, M.D.5
-
41
-
-
0003214033
-
Antiviral activity of tenofovir (PMPA) against nucleoside-resistant HIV samples
-
September 17-20; Toronto, ON, Canada. Abstract 2115
-
Miller MD, Margot NA, Hertogs K, Larder B & Miller V. Antiviral activity of tenofovir (PMPA) against nucleoside-resistant HIV samples. Presented at: 40th Interscience Conference on Antimicrobial Agents & Chemotherapy; September 17-20, 2000; Toronto, ON, Canada. Abstract 2115.
-
(2000)
40th Interscience Conference on Antimicrobial Agents & Chemotherapy
-
-
Miller, M.D.1
Margot, N.A.2
Hertogs, K.3
Larder, B.4
Miller, V.5
-
42
-
-
0242375446
-
M184V selection in suppressed subjects at week 24 may not be associated with treatment outcome (NZTA4002)
-
February 24-28; Seattle, Wash., USA. Abstract 570-T
-
Eron JJ, McClernon D, Pierce A, Sawyerr G, Gao H, St Clair M, Tolson J, Capuano G, Hernandez J & Snidow J. M184V selection in suppressed subjects at week 24 may not be associated with treatment outcome (NZTA4002). Presented at: 9th Conference on Retroviruses & Opportunistic Infections; February 24-28, 2002; Seattle, Wash., USA. Abstract 570-T.
-
(2002)
9th Conference on Retroviruses & Opportunistic Infections
-
-
Eron, J.J.1
McClernon, D.2
Pierce, A.3
Sawyerr, G.4
Gao, H.5
St. Clair, M.6
Tolson, J.7
Capuano, G.8
Hernandez, J.9
Snidow, J.10
-
43
-
-
26744478821
-
Genotypic and phenotypic changes in antiretroviral-naive patients experiencing failure on randomised treatment with abacavir, didanosine and stavudine
-
Abstract 153
-
Røge BT, Katzenstein TL, Obel N, Nielsen H, Kirk O & Gertoft J. Genotypic and phenotypic changes in antiretroviral-naive patients experiencing failure on randomised treatment with abacavir, didanosine and stavudine. Antiviral Therapy 2002; 7:S125. Abstract 153.
-
(2002)
Antiviral Therapy
, vol.7
-
-
Røge, B.T.1
Katzenstein, T.L.2
Obel, N.3
Nielsen, H.4
Kirk, O.5
Gertoft, J.6
-
44
-
-
0347351148
-
HIV-1 reverse transcriptase mutations identified by in vitro selection with tenofovir (TDF) ± abacavir and tenofovir ± lamivudine
-
Abstract 44
-
Stone C, Ait-Khaled M, Craig C & Tisdale M. HIV-1 reverse transcriptase mutations identified by in vitro selection with tenofovir (TDF) ± abacavir and tenofovir ± lamivudine. Antiviral Therapy 2002; 7:S37. Abstract 44.
-
(2002)
Antiviral Therapy
, vol.7
-
-
Stone, C.1
Ait-Khaled, M.2
Craig, C.3
Tisdale, M.4
-
45
-
-
0033921632
-
In vitro selection of mutations in the human immunodeficiency virus type 1 reverse transcriptase that decrease susceptibility to (-)-β -D-dioxolane-guanosine and suppress resistance to 3′-azido-3′ -deoxythymidine
-
Bazmi HZ, Hammond JL, Cavalcanti SCH, Chu CK, Schinazi RF & Mellors JW. In vitro selection of mutations in the human immunodeficiency virus type 1 reverse transcriptase that decrease susceptibility to (-)-β -D-dioxolane-guanosine and suppress resistance to 3′-azido-3′ -deoxythymidine. Antimicrobial Agents & Chemotherapy 2000; 44:1783-1788.
-
(2000)
Antimicrobial Agents & Chemotherapy
, vol.44
, pp. 1783-1788
-
-
Bazmi, H.Z.1
Hammond, J.L.2
Cavalcanti, S.C.H.3
Chu, C.K.4
Schinazi, R.F.5
Mellors, J.W.6
-
46
-
-
1542360605
-
Enzymatic analyses and replication capacity of HIV-1 reverse transcriptase mutants K65R and K65R+M184V
-
July 7-12; Barcelona Spain. Abstract MoPe3033
-
White KL, Margot NA, Petropoulos CJ, Wrin T, Naeger LK & Miller MD. Enzymatic analyses and replication capacity of HIV-1 reverse transcriptase mutants K65R and K65R+M184V. Presented at: XIV International AIDS Conference; July 7-12 2002; Barcelona Spain. Abstract MoPe3033.
-
(2002)
XIV International AIDS Conference
-
-
White, K.L.1
Margot, N.A.2
Petropoulos, C.J.3
Wrin, T.4
Naeger, L.K.5
Miller, M.D.6
-
47
-
-
0037076708
-
Genotypic and phenotypic analyses of HIV-1 in antiretroviral-experienced patients treated with tenofovir DF
-
Margot NA, Isaacson E, McGowan I, Cheng AK, Schooley RT & Miller MD. Genotypic and phenotypic analyses of HIV-1 in antiretroviral-experienced patients treated with tenofovir DF. AIDS 2002; 16:1227-1235.
-
(2002)
AIDS
, vol.16
, pp. 1227-1235
-
-
Margot, N.A.1
Isaacson, E.2
McGowan, I.3
Cheng, A.K.4
Schooley, R.T.5
Miller, M.D.6
-
48
-
-
0033995190
-
HIV-1 reverse transcriptase (RT) genotype and susceptibility to RT inhibitors during abacavir monotherapy and combination therapy
-
Miller V, Ait-Khaled M, Stone C, Griffin P, Mesogiti D, Cutrell A, Harrigan R, Staszewski S, Katlama C, Pearce G & Tisdale M. HIV-1 reverse transcriptase (RT) genotype and susceptibility to RT inhibitors during abacavir monotherapy and combination therapy. AIDS 2000; 14:163-171.
-
(2000)
AIDS
, vol.14
, pp. 163-171
-
-
Miller, V.1
Ait-Khaled, M.2
Stone, C.3
Griffin, P.4
Mesogiti, D.5
Cutrell, A.6
Harrigan, R.7
Staszewski, S.8
Katlama, C.9
Pearce, G.10
Tisdale, M.11
-
49
-
-
0035930584
-
Mechanism-based suppression of dideoxynucleotide resistance by K65R human immunodeficiency virus reverse transcriptase using an alpha-boranophosphate nucleoside analogue
-
Selmi B, Boretto J, Sarfati SR, Guerreiro C & Canard B. Mechanism-based suppression of dideoxynucleotide resistance by K65R human immunodeficiency virus reverse transcriptase using an alpha-boranophosphate nucleoside analogue. Journal of Biological Chemistry 2001; 276:48466-48472.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 48466-48472
-
-
Selmi, B.1
Boretto, J.2
Sarfati, S.R.3
Guerreiro, C.4
Canard, B.5
-
50
-
-
0034282409
-
Differential influence of nucleoside analog-resistance mutations K65R and L74V on the overall mutation rate and error specificity of human immunodeficiency virus type 1 reverse transcriptase
-
Shah FS, Curr KA, Hamburgh ME, Parniak M, Mitsuya H, Arnez JG & Prasad VR. Differential influence of nucleoside analog-resistance mutations K65R and L74V on the overall mutation rate and error specificity of human immunodeficiency virus type 1 reverse transcriptase. Journal of Biological Chemistry 2000; 275:27037-27044.
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 27037-27044
-
-
Shah, F.S.1
Curr, K.A.2
Hamburgh, M.E.3
Parniak, M.4
Mitsuya, H.5
Arnez, J.G.6
Prasad, V.R.7
-
51
-
-
0347351146
-
Characterization of resistance mutation patterns emerging over 2 years during first-line antiretroviral treatment with tenofovir DF (TDF) or stavudine (d4T) in combination with lamivudine (3TC) and efavirenz (EFV)
-
Abstract 135
-
Miller M, Margot N, McColl D, Wrin T, Coakley D & Cheng A. Characterization of resistance mutation patterns emerging over 2 years during first-line antiretroviral treatment with tenofovir DF (TDF) or stavudine (d4T) in combination with lamivudine (3TC) and efavirenz (EFV). Antiviral Therapy 2003; 8:S151. Abstract 135.
-
(2003)
Antiviral Therapy
, vol.8
-
-
Miller, M.1
Margot, N.2
McColl, D.3
Wrin, T.4
Coakley, D.5
Cheng, A.6
-
52
-
-
0038368654
-
Zidovudine appears to prevent selection of K65R and L74V mutations normally selected by abacavir mono- or combination therapies not containing zidovudine
-
Abstract 129
-
Ait-Khaled M, Lanier R, Richards N, Stone C, Griffin P, Gibb DM & Walker AS on behalf of PENTA 5 study team, Craig C, Loeloger AE & Tisdale M. Zidovudine appears to prevent selection of K65R and L74V mutations normally selected by abacavir mono- or combination therapies not containing zidovudine. Antiviral Therapy 2002; 7:S107. Abstract 129.
-
(2002)
Antiviral Therapy
, vol.7
-
-
Ait-Khaled, M.1
Lanier, R.2
Richards, N.3
Stone, C.4
Griffin, P.5
Gibb, D.M.6
-
53
-
-
0036156325
-
Dioxolane guanosine, the active form of the prodrug diaminopurine dioxolane, is a potent inhibitor of drug-resistant HIV-1 isolates from patients for whom standard nucleoside therapy fails
-
Mewshaw JP, Myrick FT, Wakefield DA, Hooper BJ, Harris JL, McCreedy B & Borroto-Esoda K. Dioxolane guanosine, the active form of the prodrug diaminopurine dioxolane, is a potent inhibitor of drug-resistant HIV-1 isolates from patients for whom standard nucleoside therapy fails. Journal of Acquired Immune Deficiency Syndromes 2002; 29:11-20.
-
(2002)
Journal of Acquired Immune Deficiency Syndromes
, vol.29
, pp. 11-20
-
-
Mewshaw, J.P.1
Myrick, F.T.2
Wakefield, D.A.3
Hooper, B.J.4
Harris, J.L.5
McCreedy, B.6
Borroto-Esoda, K.7
-
54
-
-
0025950055
-
Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase
-
St Clair MH, Martin JL, Tudor-Williams G, Bach MC, Vavro CL, King DM, Kellam P, Kemp SD & Larder BA. Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase. Science 1991; 253:1557-1559.
-
(1991)
Science
, vol.253
, pp. 1557-1559
-
-
St. Clair, M.H.1
Martin, J.L.2
Tudor-Williams, G.3
Bach, M.C.4
Vavro, C.L.5
King, D.M.6
Kellam, P.7
Kemp, S.D.8
Larder, B.A.9
-
55
-
-
0028607429
-
Didanosine resistance in HIV-infected patients switched from zidovudine to didanosine monotherapy
-
Kozal MJ, Kroodsma K, Winters MA, Shafer RW, Efron B, Katzenstein DA & Merigan TC. Didanosine resistance in HIV-infected patients switched from zidovudine to didanosine monotherapy. Annals of Internal Medicine 1994; 121:263-268.
-
(1994)
Annals of Internal Medicine
, vol.121
, pp. 263-268
-
-
Kozal, M.J.1
Kroodsma, K.2
Winters, M.A.3
Shafer, R.W.4
Efron, B.5
Katzenstein, D.A.6
Merigan, T.C.7
-
56
-
-
0028940084
-
Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides
-
Shirasaka T, Kavlick MF, Ueno T, Gao WY, Kojima E, Alcaide ML, Chokekijchai S, Roy BM, Arnold E, Yarchoan R et al. Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides. Proceedings of the National Academy of Sciences, USA 1995; 92:2398-2402.
-
(1995)
Proceedings of the National Academy of Sciences, USA
, vol.92
, pp. 2398-2402
-
-
Shirasaka, T.1
Kavlick, M.F.2
Ueno, T.3
Gao, W.Y.4
Kojima, E.5
Alcaide, M.L.6
Chokekijchai, S.7
Roy, B.M.8
Arnold, E.9
Yarchoan, R.10
-
57
-
-
0031802175
-
Emergence of multi-dideoxynucleoside-resistant human immunodeficiency virus type 1 variants, viral sequence variation, and disease progression in patients receiving antiretroviral chemotherapy
-
Kavlick MF, Wyvill K, Yarchoan R & Mitsuya H. Emergence of multi-dideoxynucleoside-resistant human immunodeficiency virus type 1 variants, viral sequence variation, and disease progression in patients receiving antiretroviral chemotherapy. Journal of Infectious Diseases 1998; 177:1506-1513.
-
(1998)
Journal of Infectious Diseases
, vol.177
, pp. 1506-1513
-
-
Kavlick, M.F.1
Wyvill, K.2
Yarchoan, R.3
Mitsuya, H.4
-
58
-
-
0029007143
-
Drug resistance and heterogeneous long-term virologic responses of human immunodeficiency virus type 1-infected subjects to zidovudine and didanosine combination therapy
-
The AIDS Clinical Trials Group 143 Virology Team
-
Shafer RW, Iversen AK, Winters MA, Aguiniga E, Katzenstein DA & Merigan TC. Drug resistance and heterogeneous long-term virologic responses of human immunodeficiency virus type 1-infected subjects to zidovudine and didanosine combination therapy. The AIDS Clinical Trials Group 143 Virology Team. Journal of Infectious Diseases 1995; 172:70-78.
-
(1995)
Journal of Infectious Diseases
, vol.172
, pp. 70-78
-
-
Shafer, R.W.1
Iversen, A.K.2
Winters, M.A.3
Aguiniga, E.4
Katzenstein, D.A.5
Merigan, T.C.6
-
59
-
-
0347981391
-
Choice of co-nucleoside analog in d4T-treated subjects may influence the pattern of thymidine analog mutations (TAMs) and multi-nucleoside resistance mutations (MNRs)
-
February 24-28; Seattle, Wash., USA. Poster 568-T
-
Ross L, Liao Q, Henry K, Cohen C, Hirani A, Fisher R, St Clair M & Hernandez J. Choice of co-nucleoside analog in d4T-treated subjects may influence the pattern of thymidine analog mutations (TAMs) and multi-nucleoside resistance mutations (MNRs). Presented at: 9th Conference on Retroviruses & Opportunistic Infections; February 24-28 2002; Seattle, Wash., USA. Poster 568-T.
-
(2002)
9th Conference on Retroviruses & Opportunistic Infections
-
-
Ross, L.1
Liao, Q.2
Henry, K.3
Cohen, C.4
Hirani, A.5
Fisher, R.6
St. Clair, M.7
Hernandez, J.8
-
60
-
-
0035884247
-
Comparison of genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 isolates from patients treated with stavudine and didanosine or zidovudine and lamivudine
-
Picard V, Angelini E, Maillard A, Race E, Clavel F, Chene G, Ferchal F & Molina JM. Comparison of genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 isolates from patients treated with stavudine and didanosine or zidovudine and lamivudine. Journal of Infectious Diseases 2001; 184:781-784.
-
(2001)
Journal of Infectious Diseases
, vol.184
, pp. 781-784
-
-
Picard, V.1
Angelini, E.2
Maillard, A.3
Race, E.4
Clavel, F.5
Chene, G.6
Ferchal, F.7
Molina, J.M.8
-
61
-
-
0033022106
-
Highly drug-resistant HIV-1 clinical isolates are cross-resistant to many antiretroviral compounds in current clinical development
-
Palmer S, Shafer RW & Merigan TC. Highly drug-resistant HIV-1 clinical isolates are cross-resistant to many antiretroviral compounds in current clinical development. AIDS 1999; 13:661-667.
-
(1999)
AIDS
, vol.13
, pp. 661-667
-
-
Palmer, S.1
Shafer, R.W.2
Merigan, T.C.3
-
62
-
-
0032817241
-
A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance
-
Larder BA, Bloor S, Kemp SD, Hertogs K, Desmet RL, Miller V, Sturmer M, Staszewski S, Ren J, Stammers DK, Stuart DI & Pauwels R. A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance. Antimicrobial Agents & Chemotherapy 1999; 43:1961-1967.
-
(1999)
Antimicrobial Agents & Chemotherapy
, vol.43
, pp. 1961-1967
-
-
Larder, B.A.1
Bloor, S.2
Kemp, S.D.3
Hertogs, K.4
Desmet, R.L.5
Miller, V.6
Sturmer, M.7
Staszewski, S.8
Ren, J.9
Stammers, D.K.10
Stuart, D.I.11
Pauwels, R.12
-
63
-
-
0034999828
-
Genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 variants with insertions or deletions in the reverse transcriptase (RT): Multicenter study of patients treated with RT inhibitors
-
French Agence Nationale de Recherches sur le SIDA
-
Masquelier B, Race E, Tamalet C, Descamps D, Izopet J, Buffet-Janvresse C, Ruffault A, Mohammed AS, Cottalorda J, Schmuck A, Calvez V, Dam E, Fleury H & Brun-Vezinet F; ANRS AC11 Resistance study group. French Agence Nationale de Recherches sur le SIDA. Genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 variants with insertions or deletions in the reverse transcriptase (RT): multicenter study of patients treated with RT inhibitors. Antimicrobial Agents & Chemotherapy 2001; 45:1836-1842.
-
(2001)
Antimicrobial Agents & Chemotherapy
, vol.45
, pp. 1836-1842
-
-
Masquelier, B.1
Race, E.2
Tamalet, C.3
Descamps, D.4
Izopet, J.5
Buffet-Janvresse, C.6
Ruffault, A.7
Mohammed, A.S.8
Cottalorda, J.9
Schmuck, A.10
Calvez, V.11
Dam, E.12
Fleury, H.13
Brun-Vezinet, F.14
-
64
-
-
0034963036
-
Biochemical mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to stavudine
-
Lennerstrand J, Stammers DK & Larder BA. Biochemical mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to stavudine. Antimicrobial Agents & Chemotherapy 2001; 45:2144-2146.
-
(2001)
Antimicrobial Agents & Chemotherapy
, vol.45
, pp. 2144-2146
-
-
Lennerstrand, J.1
Stammers, D.K.2
Larder, B.A.3
-
65
-
-
0034948070
-
Correlation between viral resistance to zidovudine and resistance at the reverse transcriptase level for a panel of human immunodeficiency virus type 1 mutants
-
Lennerstrand J, Hertogs K, Stammers DK & Larder BA. Correlation between viral resistance to zidovudine and resistance at the reverse transcriptase level for a panel of human immunodeficiency virus type 1 mutants. Journal of Virology 2001; 75:7202-7205.
-
(2001)
Journal of Virology
, vol.75
, pp. 7202-7205
-
-
Lennerstrand, J.1
Hertogs, K.2
Stammers, D.K.3
Larder, B.A.4
-
66
-
-
0037334586
-
Effects of dipeptide insertions between codons 69 and 70 of human immunodeficiency virus type 1 reverse transcriptase on primer unblocking, deoxynucleoside triphosphate inhibition, and DNA chain elongation
-
Meyer PR, Lennerstrand J, Matsuura SE, Larder BA & Scott WA. Effects of dipeptide insertions between codons 69 and 70 of human immunodeficiency virus type 1 reverse transcriptase on primer unblocking, deoxynucleoside triphosphate inhibition, and DNA chain elongation. Journal of Virology 2003; 77:3871-3877.
-
(2003)
Journal of Virology
, vol.77
, pp. 3871-3877
-
-
Meyer, P.R.1
Lennerstrand, J.2
Matsuura, S.E.3
Larder, B.A.4
Scott, W.A.5
-
67
-
-
0033606540
-
Drug-resistance genotyping in HIV-1 therapy: The VIRADAPT randomised controlled trial
-
Durant J, Clevenbergh P, Halfon P, Delgiudice P, Porsin S, Simonet P, Montagne N, Boucher CA, Schapiro JM & Dellamonica P. Drug-resistance genotyping in HIV-1 therapy: the VIRADAPT randomised controlled trial. Lancet 1999; 353:2195-2199.
-
(1999)
Lancet
, vol.353
, pp. 2195-2199
-
-
Durant, J.1
Clevenbergh, P.2
Halfon, P.3
Delgiudice, P.4
Porsin, S.5
Simonet, P.6
Montagne, N.7
Boucher, C.A.8
Schapiro, J.M.9
Dellamonica, P.10
-
68
-
-
0033920318
-
A randomized study of antiretroviral management based on plasma genotypic antiretroviral resistance testing in patients failing therapy
-
CPCRA 046 Study Team for the Terry Beirn Community Programs for Clinical Research on AIDS
-
Baxter JD, Mayers DL, Wentworth DN, Neaton JD, Hoover ML, Winters MA, Mannheimer SB, Thompson MA, Abrams DI, Brizz BJ, Ioannidis JP & Merigan TC. A randomized study of antiretroviral management based on plasma genotypic antiretroviral resistance testing in patients failing therapy. CPCRA 046 Study Team for the Terry Beirn Community Programs for Clinical Research on AIDS. AIDS 2000; 14:F83-F93.
-
(2000)
AIDS
, vol.14
-
-
Baxter, J.D.1
Mayers, D.L.2
Wentworth, D.N.3
Neaton, J.D.4
Hoover, M.L.5
Winters, M.A.6
Mannheimer, S.B.7
Thompson, M.A.8
Abrams, D.I.9
Brizz, B.J.10
Ioannidis, J.P.11
Merigan, T.C.12
-
69
-
-
0344593433
-
The relation between baseline HIV drug resistance and response to antiretroviral therapy: Reanalysis of retrospective and prospective studies using a standardized data analysis plan
-
DeGruttola V, Dix L, D'Aquila R, Holder D, Phillips A, Ait-Khaled M, Baxter J, Clevenbergh P, Hammer S, Harrigan R, Katzenstein D, Lanier R, Miller M, Para M, Yerly S, Zolopa A, Murray J, Patick A, Miller V, Castillo S, Pedneault & Mellors J. The relation between baseline HIV drug resistance and response to antiretroviral therapy: reanalysis of retrospective and prospective studies using a standardized data analysis plan. Antiviral Therapy 2000; 5:41-48.
-
(2000)
Antiviral Therapy
, vol.5
, pp. 41-48
-
-
DeGruttola, V.1
Dix, L.2
D'Aquila, R.3
Holder, D.4
Phillips, A.5
Ait-Khaled, M.6
Baxter, J.7
Clevenbergh, P.8
Hammer, S.9
Harrigan, R.10
Katzenstein, D.11
Lanier, R.12
Miller, M.13
Para, M.14
Yerly, S.15
Zolopa, A.16
Murray, J.17
Patick, A.18
Miller, V.19
Castillo, S.20
Pedneault21
Mellors, J.22
more..
-
70
-
-
0037169170
-
Clinical utility of HIV-1 genotyping and expert advice: The Havana trial
-
Tural C, Ruiz L, Holtzer C, Schapiro J, Viciana P, Gonzalez J, Domingo P, Boucher C, Rey-Joly & Clotet B; Havana Study Group. Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. AIDS 2002; 16:209-218.
-
(2002)
AIDS
, vol.16
, pp. 209-218
-
-
Tural, C.1
Ruiz, L.2
Holtzer, C.3
Schapiro, J.4
Viciana, P.5
Gonzalez, J.6
Domingo, P.7
Boucher, C.8
Rey-Joly9
Clotet, B.10
-
71
-
-
0037040360
-
A randomized trial assessing the impact of phenotypic resistance testing on antiretroviral therapy
-
Cohen CJ, Hunt S, Sension M, Farthing C, Conant M, Jacobson S, Nadler J, Verbiest W, Hertogs K, Ames M, Rinehart AR & Graham NM; VIRA3001 Study Team. A randomized trial assessing the impact of phenotypic resistance testing on antiretroviral therapy. AIDS 2002; 16:579-588.
-
(2002)
AIDS
, vol.16
, pp. 579-588
-
-
Cohen, C.J.1
Hunt, S.2
Sension, M.3
Farthing, C.4
Conant, M.5
Jacobson, S.6
Nadler, J.7
Verbiest, W.8
Hertogs, K.9
Ames, M.10
Rinehart, A.R.11
Graham, N.M.12
-
72
-
-
0003667696
-
-
Washington, DC: US Dept of Health and Human Services
-
US Department of Health and Human Services. Guidelines for the Use of Antiretroviral Agents in HIV-Infected Adults and Adolescents. Washington, DC: US Dept of Health and Human Services; 2001. Available at: http://aidsinfo.nih.gov/guidelines/adult/AA_111003.pdf. Accessed November 10, 2003.
-
(2001)
Guidelines for the Use of Antiretroviral Agents in HIV-Infected Adults and Adolescents
-
-
-
73
-
-
0035895674
-
Clinical and laboratory guidelines for the use of HIV-1 drug resistance testing as part of treatment management: Recommendations for the European setting
-
The EuroGuidelines Group for HIV. Clinical and laboratory guidelines for the use of HIV-1 drug resistance testing as part of treatment management: recommendations for the European setting. AIDS 2001; 15:309-320.
-
(2001)
AIDS
, vol.15
, pp. 309-320
-
-
-
74
-
-
0036768696
-
Impact of stavudine phenotype and thymidine analogues mutations on viral response to stavudine plus lamivudine in ALTIS 2 ANRS trial
-
Calvez V, Costagliola D, Descamps D, Yvon A, Collin G, Cecile A, Delaugerre C, Damond F, Marcelin AG, Matheron S, Simon A, Valantin MA, Katlama C & Brun-Vezinet F. Impact of stavudine phenotype and thymidine analogues mutations on viral response to stavudine plus lamivudine in ALTIS 2 ANRS trial. Antiviral Therapy 2002; 7:211-218.
-
(2002)
Antiviral Therapy
, vol.7
, pp. 211-218
-
-
Calvez, V.1
Costagliola, D.2
Descamps, D.3
Yvon, A.4
Collin, G.5
Cecile, A.6
Delaugerre, C.7
Damond, F.8
Marcelin, A.G.9
Matheron, S.10
Simon, A.11
Valantin, M.A.12
Katlama, C.13
Brun-Vezinet, F.14
-
75
-
-
0036797093
-
Subtle decreases in stavudine phenotypic susceptibility predict poor virologic response to stavudine monotherapy in zidovudine-experienced patients
-
Shulman NS, Hughes MD, Winters MA, Shafer RW, Zolopa AR, Hellmann NS, Bates M, Whitcomb JM & Katzenstein DA. Subtle decreases in stavudine phenotypic susceptibility predict poor virologic response to stavudine monotherapy in zidovudine-experienced patients. Journal of Acquired Immune Deficiency Syndromes 2002; 31:121-127.
-
(2002)
Journal of Acquired Immune Deficiency Syndromes
, vol.31
, pp. 121-127
-
-
Shulman, N.S.1
Hughes, M.D.2
Winters, M.A.3
Shafer, R.W.4
Zolopa, A.R.5
Hellmann, N.S.6
Bates, M.7
Whitcomb, J.M.8
Katzenstein, D.A.9
-
76
-
-
0141767757
-
Mutations in HIV-1 protease associated with resistance to amprenavir contribute towards phenotypic resistance to lopinavir
-
Abstract 24
-
Parkin NT, Chappey C & Petropoulos CJ. Mutations in HIV-1 protease associated with resistance to amprenavir contribute towards phenotypic resistance to lopinavir. Antiviral Therapy 2002; 7:S23. Abstract 24.
-
(2002)
Antiviral Therapy
, vol.7
-
-
Parkin, N.T.1
Chappey, C.2
Petropoulos, C.J.3
-
77
-
-
0036797415
-
Phenotypic and genotypic HIV-1 drug resistance assays provide complementary information
-
Parkin N, Chappey C, Maroldo L, Bates M, Hellmann NS & Petropoulos CJ. Phenotypic and genotypic HIV-1 drug resistance assays provide complementary information. Journal of Acquired Immune Deficiency Syndromes 2002; 31:128-136.
-
(2002)
Journal of Acquired Immune Deficiency Syndromes
, vol.31
, pp. 128-136
-
-
Parkin, N.1
Chappey, C.2
Maroldo, L.3
Bates, M.4
Hellmann, N.S.5
Petropoulos, C.J.6
-
78
-
-
18344409610
-
The clinical relevance of non-nucleoside reverse transcriptase inhibitor hypersusceptibility: A prospective cohort analysis
-
Haubrich RH, Kemper CA, Hellmann NS & the CCTG Study Team. The clinical relevance of non-nucleoside reverse transcriptase inhibitor hypersusceptibility: a prospective cohort analysis. AIDS 2002; 16:F33-F40.
-
(2002)
AIDS
, vol.16
-
-
Haubrich, R.H.1
Kemper, C.A.2
Hellmann, N.S.3
-
79
-
-
0001903816
-
CCTG 575: A randomized, prospective study of phenotype testing versus standard of care for patients failing antiretroviral therapy
-
Abstract 80
-
Haubrich R, Keiser P, Kemper C et al. & the CCTG Study Team. CCTG 575: a randomized, prospective study of phenotype testing versus standard of care for patients failing antiretroviral therapy. Antiviral Therapy 2001; 6(Suppl. 1):63. Abstract 80.
-
(2001)
Antiviral Therapy
, vol.6
, Issue.SUPPL. 1
, pp. 63
-
-
Haubrich, R.1
Keiser, P.2
Kemper, C.3
-
80
-
-
0037978856
-
Long-term clinical efficacy of resistance testing: Results of the CERT trial
-
Abstract 158
-
Wegner S, Wallace M, Tasker S, Aronson N, Blazes D, Tamminga C, Fraser S, Stephen K, Jagodzinski L, Vahey M, Tracy L, Rinehart A, Graham N, Hertogs K & Birx D. Long-term clinical efficacy of resistance testing: results of the CERT trial. Antiviral Therapy 2002; 7:S129. Abstract 158.
-
(2002)
Antiviral Therapy
, vol.7
-
-
Wegner, S.1
Wallace, M.2
Tasker, S.3
Aronson, N.4
Blazes, D.5
Tamminga, C.6
Fraser, S.7
Stephen, K.8
Jagodzinski, L.9
Vahey, M.10
Tracy, L.11
Rinehart, A.12
Graham, N.13
Hertogs, K.14
Birx, D.15
-
81
-
-
0026565278
-
Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine
-
Kellam P, Boucher CAB & Larder BA. Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine. Proceedings of the National Academy of Sciences, USA 1992; 89:1934-1938.
-
(1992)
Proceedings of the National Academy of Sciences, USA
, vol.89
, pp. 1934-1938
-
-
Kellam, P.1
Boucher, C.A.B.2
Larder, B.A.3
-
82
-
-
0029843986
-
Significance of amino acid variation at human immunodeficiency virus type 1 reverse transcriptase residue 210 for zidovudine susceptibility
-
Harrigan PR, Kinghorn I, Bloor S, Kemp SD, Najera I, Kohli A & Larder BA. Significance of amino acid variation at human immunodeficiency virus type 1 reverse transcriptase residue 210 for zidovudine susceptibility. Journal of Virology 1996; 70:5930-5934.
-
(1996)
Journal of Virology
, vol.70
, pp. 5930-5934
-
-
Harrigan, P.R.1
Kinghorn, I.2
Bloor, S.3
Kemp, S.D.4
Najera, I.5
Kohli, A.6
Larder, B.A.7
-
83
-
-
0026570624
-
Ordered appearance of zidovudine resistance mutations during treatment of 18 human immunodeficiency virus-positive subjects
-
Boucher CA, O'Sullivan E, Mulder JW, Ramautarsing C, Kellam P, Darby G, Lange JM, Goudsmit J & Larder BA. Ordered appearance of zidovudine resistance mutations during treatment of 18 human immunodeficiency virus-positive subjects. Journal of Infectious Diseases 1992; 165:105-110.
-
(1992)
Journal of Infectious Diseases
, vol.165
, pp. 105-110
-
-
Boucher, C.A.1
O'Sullivan, E.2
Mulder, J.W.3
Ramautarsing, C.4
Kellam, P.5
Darby, G.6
Lange, J.M.7
Goudsmit, J.8
Larder, B.A.9
-
84
-
-
0036204427
-
Frequency of mutations conferring resistance to nucleoside reverse transcriptase inhibitors in human immunodeficiency virus type 1-infected patients in Korea
-
Cho YK, Sung H, Ahn SH, Bae IG, Woo JH, Won YH, Kim DG & Kang MW. Frequency of mutations conferring resistance to nucleoside reverse transcriptase inhibitors in human immunodeficiency virus type 1-infected patients in Korea. Journal of Clinical Microbiology 2002; 40:1319-1325.
-
(2002)
Journal of Clinical Microbiology
, vol.40
, pp. 1319-1325
-
-
Cho, Y.K.1
Sung, H.2
Ahn, S.H.3
Bae, I.G.4
Woo, J.H.5
Won, Y.H.6
Kim, D.G.7
Kang, M.W.8
-
85
-
-
26744447700
-
Selection of thymidine analogue mutations by nucleoside reverse transcriptase inhibitors occurs step by step and through two different pathways
-
Abstract 40
-
Marcelin AG, Wirden M, Delaugerre C, Viegas P, Simon A, Katlama C & Calvez V. Selection of thymidine analogue mutations by nucleoside reverse transcriptase inhibitors occurs step by step and through two different pathways. Antiviral Therapy 2002; 7:S34. Abstract 40.
-
(2002)
Antiviral Therapy
, vol.7
-
-
Marcelin, A.G.1
Wirden, M.2
Delaugerre, C.3
Viegas, P.4
Simon, A.5
Katlama, C.6
Calvez, V.7
-
86
-
-
0001380955
-
d4T-based combination therapy selects for 'ZDV like' HIV-1 resistance mutations in ZDV-naive adult patients
-
September 26-29; San Francisco, Calif., USA. Abstract 429
-
Ross LL, Johnson M, Hernandez J et al. d4T-based combination therapy selects for 'ZDV like' HIV-1 resistance mutations in ZDV-naive adult patients. Presented at: 39th International Conference on Antimicrobial Agents & Chemotherapy; September 26-29 1999; San Francisco, Calif., USA. Abstract 429.
-
(1999)
39th International Conference on Antimicrobial Agents & Chemotherapy
-
-
Ross, L.L.1
Johnson, M.2
Hernandez, J.3
-
87
-
-
0037090053
-
Selection of zidovudine resistance mutations and escape of human immunodeficiency virus type 1 from antiretroviral pressure in stavudine-treated pediatric patients
-
Maxeiner HG, Keulen W, Schuurman R, Bijen M, de Graaf L, van Wijk A, Back N, Kline MW, Boucher CA & Nijhuis M. Selection of zidovudine resistance mutations and escape of human immunodeficiency virus type 1 from antiretroviral pressure in stavudine-treated pediatric patients. Journal of Infectious Diseases 2002; 185:1070-1076.
-
(2002)
Journal of Infectious Diseases
, vol.185
, pp. 1070-1076
-
-
Maxeiner, H.G.1
Keulen, W.2
Schuurman, R.3
Bijen, M.4
De Graaf, L.5
Van Wijk, A.6
Back, N.7
Kline, M.W.8
Boucher, C.A.9
Nijhuis, M.10
-
88
-
-
0028332029
-
Novel mutation (V75T) in human immunodeficiency virus type 1 reverse transcriptase confers resistance to 2′,3′-didehydro-2′ ,3′-dideoxythymidine in cell culture
-
Lacey SF & Larder BA. Novel mutation (V75T) in human immunodeficiency virus type 1 reverse transcriptase confers resistance to 2′,3′-didehydro-2′,3′-dideoxythymidine in cell culture. Antimicrobial Agents & Chemotherapy 1994; 38:1428-1432.
-
(1994)
Antimicrobial Agents & Chemotherapy
, vol.38
, pp. 1428-1432
-
-
Lacey, S.F.1
Larder, B.A.2
-
89
-
-
0027988547
-
Genotypic and phenotypic analysis of human immunodeficiency virus type 1 isolates from patients on prolonged stavudine therapy
-
Lin PF, Samanta H, Rose RE, Patick AK, Trimble J, Bechtold CM, Revie DR, Khan NC, Federici ME, Li H et al. Genotypic and phenotypic analysis of human immunodeficiency virus type 1 isolates from patients on prolonged stavudine therapy. Journal of Infectious Diseases 1994; 170:1157-1164.
-
(1994)
Journal of Infectious Diseases
, vol.170
, pp. 1157-1164
-
-
Lin, P.F.1
Samanta, H.2
Rose, R.E.3
Patick, A.K.4
Trimble, J.5
Bechtold, C.M.6
Revie, D.R.7
Khan, N.C.8
Federici, M.E.9
Li, H.10
-
90
-
-
0029563673
-
Treatment with lamivudine, zidovudine, or both in HIV-positive patients with 200 to 500 CD4+ cells per cubic millimeter
-
North American HIV Working Party
-
Eron JJ, Benoit SL, Jemsek J, MacArthur RD, Santana J, Quinn JB, Kuritzkes DR, Fallon MA & Rubin M. Treatment with lamivudine, zidovudine, or both in HIV-positive patients with 200 to 500 CD4+ cells per cubic millimeter. North American HIV Working Party. New England Journal of Medicine 1995; 333:1662-1669.
-
(1995)
New England Journal of Medicine
, vol.333
, pp. 1662-1669
-
-
Eron, J.J.1
Benoit, S.L.2
Jemsek, J.3
MacArthur, R.D.4
Santana, J.5
Quinn, J.B.6
Kuritzkes, D.R.7
Fallon, M.A.8
Rubin, M.9
-
91
-
-
0038655202
-
Multivariate analyses of antiviral response to tenofovir DF therapy in antiretroviral-experienced patients
-
Abstract 14
-
Miller MD, Zhong L, Chen S, Margot NA & Wulfsohn M. Multivariate analyses of antiviral response to tenofovir DF therapy in antiretroviral-experienced patients. Antiviral Therapy 2002; 7:S12. Abstract 14.
-
(2002)
Antiviral Therapy
, vol.7
-
-
Miller, M.D.1
Zhong, L.2
Chen, S.3
Margot, N.A.4
Wulfsohn, M.5
-
92
-
-
0142041082
-
-
Foster City, Calif., USA: Gilead
-
Viread [package insert]. Foster City, Calif., USA: Gilead; 2002.
-
(2002)
Viread [Package Insert]
-
-
-
93
-
-
0012612571
-
Rate of emergence of thymidine analogue resistance mutations in HIV-1 reverse transcriptase selected by stavudine or zidovudine-based regimens in treatment-naive patients
-
Abstract 36
-
Kuritzkes DR, Bassett RL, Young RK et al., for the ACTG 306 and 370 Protocol Teams. Rate of emergence of thymidine analogue resistance mutations in HIV-1 reverse transcriptase selected by stavudine or zidovudine-based regimens in treatment-naive patients. Antiviral Therapy 2002; 7:S31. Abstract 36.
-
(2002)
Antiviral Therapy
, vol.7
-
-
Kuritzkes, D.R.1
Bassett, R.L.2
Young, R.K.3
-
94
-
-
0035214534
-
Failure of stavudine-lamivudine combination therapy in antiretroviral-naive patients with AZT-like HIV-1 resistance mutations
-
Sarmati L, Nicastri E, Parisi SG, D'Ettorre G, Narciso P, Mancino G, Gallo I, Abbadessa V, Dalle NE, Traina C, Vullo V & Andreoni M. Failure of stavudine-lamivudine combination therapy in antiretroviral-naive patients with AZT-like HIV-1 resistance mutations. Journal of Medical Virology 2001; 65:631-636.
-
(2001)
Journal of Medical Virology
, vol.65
, pp. 631-636
-
-
Sarmati, L.1
Nicastri, E.2
Parisi, S.G.3
D'Ettorre, G.4
Narciso, P.5
Mancino, G.6
Gallo, I.7
Abbadessa, V.8
Dalle, N.E.9
Traina, C.10
Vullo, V.11
Andreoni, M.12
-
95
-
-
17544391491
-
A novel human immunodeficiency virus type 1 reverse transcriptase mutational pattern confers phenotypic lamivudine resistance in the absence of mutation 184V
-
Hertogs K, Bloor S, De Vroey V, van Den Eynde C, Dehertogh P, van Cauwenberge A, Sturmer M, Alcorn T, Wegner S, van Houtte M, Miller V & Larder BA. A novel human immunodeficiency virus type 1 reverse transcriptase mutational pattern confers phenotypic lamivudine resistance in the absence of mutation 184V. Antimicrobial Agents & Chemotherapy 2000; 44:568-573.
-
(2000)
Antimicrobial Agents & Chemotherapy
, vol.44
, pp. 568-573
-
-
Hertogs, K.1
Bloor, S.2
De Vroey, V.3
Van Den Eynde, C.4
Dehertogh, P.5
Van Cauwenberge, A.6
Sturmer, M.7
Alcorn, T.8
Wegner, S.9
Van Houtte, M.10
Miller, V.11
Larder, B.A.12
-
96
-
-
0034275159
-
Prevalence of novel lamivudine-resistant genotypes (E44D/A, V118I) in naive and pretreated HIV-infected individuals
-
Gallego O, Briones C, Corral A & Soriano V. Prevalence of novel lamivudine-resistant genotypes (E44D/A, V118I) in naive and pretreated HIV-infected individuals. Journal of Acquired Immune Deficiency Syndromes 2000; 25:95-96.
-
(2000)
Journal of Acquired Immune Deficiency Syndromes
, vol.25
, pp. 95-96
-
-
Gallego, O.1
Briones, C.2
Corral, A.3
Soriano, V.4
-
97
-
-
0036534427
-
Broad nucleoside-analogue resistance implications for human immunodeficiency virus type 1 reverse-transcriptase mutations at codons 44 and 118
-
Romano L, Venturi G, Bloor S, Harrigan R, Larder BA, Major JC & Zazzi M. Broad nucleoside-analogue resistance implications for human immunodeficiency virus type 1 reverse-transcriptase mutations at codons 44 and 118. Journal of Infectious Diseases 2002; 185:898-904.
-
(2002)
Journal of Infectious Diseases
, vol.185
, pp. 898-904
-
-
Romano, L.1
Venturi, G.2
Bloor, S.3
Harrigan, R.4
Larder, B.A.5
Major, J.C.6
Zazzi, M.7
-
98
-
-
0036135318
-
Prediction of abacavir resistance from genotypic data: Impact of zidovudine and lamivudine resistance in vitro and in vivo
-
Walter H, Schmidt B, Werwein M, Schwingel E & Korn K. Prediction of abacavir resistance from genotypic data: impact of zidovudine and lamivudine resistance in vitro and in vivo. Antimicrobial Agents & Chemotherapy 2002; 46:89-94.
-
(2002)
Antimicrobial Agents & Chemotherapy
, vol.46
, pp. 89-94
-
-
Walter, H.1
Schmidt, B.2
Werwein, M.3
Schwingel, E.4
Korn, K.5
-
99
-
-
0028137794
-
Resistance to AZT and ddC during long-term combination therapy in patients with advanced infection with human immunodeficiency virus
-
Richman DD, Meng TC, Spector SA, Fischl MA, Resnick L & Lai S. Resistance to AZT and ddC during long-term combination therapy in patients with advanced infection with human immunodeficiency virus. Journal of Acquired Immune Deficiency Syndromes 1994; 7:135-138.
-
(1994)
Journal of Acquired Immune Deficiency Syndromes
, vol.7
, pp. 135-138
-
-
Richman, D.D.1
Meng, T.C.2
Spector, S.A.3
Fischl, M.A.4
Resnick, L.5
Lai, S.6
-
100
-
-
0036721511
-
Impact of human immunodeficiency virus type 1 subtypes on virologic response and emergence of drug resistance among children in the Paediatric European Network for Treatment of AIDS (PENTA) 5 trial
-
Pillay D, Walker AS, Gibb DM, de Rossi A, Kaye S, Ait-Khaled M, Munoz-Fernandez M & Babiker A. Impact of human immunodeficiency virus type 1 subtypes on virologic response and emergence of drug resistance among children in the Paediatric European Network for Treatment of AIDS (PENTA) 5 trial. Journal of Infectious Diseases 2002; 186:617-625.
-
(2002)
Journal of Infectious Diseases
, vol.186
, pp. 617-625
-
-
Pillay, D.1
Walker, A.S.2
Gibb, D.M.3
De Rossi, A.4
Kaye, S.5
Ait-Khaled, M.6
Munoz-Fernandez, M.7
Babiker, A.8
-
101
-
-
0036972280
-
Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1 infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (The PENTA 5 Trial)
-
Gibb DM, Walker AS, Kaye S, De Rossi A, Ait-Khaled M, Pillay D, Munoz-Fernandez MA, Loveday C, Compagnucci A, Dunn DT & Babiker AG. Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1 infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (The PENTA 5 Trial). Antiviral Therapy 2002; 7:293-303.
-
(2002)
Antiviral Therapy
, vol.7
, pp. 293-303
-
-
Gibb, D.M.1
Walker, A.S.2
Kaye, S.3
De Rossi, A.4
Ait-Khaled, M.5
Pillay, D.6
Munoz-Fernandez, M.A.7
Loveday, C.8
Compagnucci, A.9
Dunn, D.T.10
Babiker, A.G.11
-
102
-
-
0007523835
-
START observational study: Longitudinal follow-up of virologic and immunologic responses in START I and START II patients
-
February 4-8; Chicago, Ill., USA. Abstract 314
-
Murphy R, Santana J, Squires K, Yangco B, Peterson D, Adams J, Mauney J, Perry M, Grosso R, Tudor J, Stevens M & the Start Observation Team. START observational study: longitudinal follow-up of virologic and immunologic responses in START I and START II patients. Presented at: 8th Conference on Retroviruses & Opportunistic Infections; February 4-8 2001; Chicago, Ill., USA. Abstract 314.
-
(2001)
8th Conference on Retroviruses & Opportunistic Infections
-
-
Murphy, R.1
Santana, J.2
Squires, K.3
Yangco, B.4
Peterson, D.5
Adams, J.6
Mauney, J.7
Perry, M.8
Grosso, R.9
Tudor, J.10
Stevens, M.11
-
103
-
-
0003259742
-
Viral rebound in the presence of indinavir without protease inhibitor resistance
-
January 31-February 4 1999; Chicago, Ill., USA. Abstract LB12
-
Havlir D, Hellman N, Petropoulos C et al. Viral rebound in the presence of indinavir without protease inhibitor resistance. Presented at: 6th Conference on Retroviruses & Opportunistic Infections; January 31-February 4 1999; Chicago, Ill., USA. Abstract LB12.
-
(1999)
6th Conference on Retroviruses & Opportunistic Infections
-
-
Havlir, D.1
Hellman, N.2
Petropoulos, C.3
-
104
-
-
0347981389
-
Genotypic patterns in virologic failures on lamivudine/zidovudine-based triple and quadruple therapy (NZTA4002)
-
September 17-20 2000; Toronto, ON, Canada. Abstract 1274
-
Eron J, Arduino R, Junod P et al. Genotypic patterns in virologic failures on lamivudine/zidovudine-based triple and quadruple therapy (NZTA4002). Presented at: 40th Interscience Conference on Antimicrobial Agents & Chemotherapy; September 17-20 2000; Toronto, ON, Canada. Abstract 1274.
-
(2000)
40th Interscience Conference on Antimicrobial Agents & Chemotherapy
-
-
Eron, J.1
Arduino, R.2
Junod, P.3
-
105
-
-
0032899327
-
Treatment with amprenavir alone or amprenavir with zidovudine and lamivudine in adults with human immunodeficiency virus infection
-
AIDS Clinical Trials Group 347 Study Team
-
Murphy RL, Gulick RM, DeGruttola V, D'Aquila RT, Eron JJ, Sommadossi JP, Currier JS, Smeaton L, Frank I, Caliendo AM, Gerber JG, Tung R & Kuritzkes DR. Treatment with amprenavir alone or amprenavir with zidovudine and lamivudine in adults with human immunodeficiency virus infection. AIDS Clinical Trials Group 347 Study Team. Journal of Infectious Diseases 1999; 179:808-816.
-
(1999)
Journal of Infectious Diseases
, vol.179
, pp. 808-816
-
-
Murphy, R.L.1
Gulick, R.M.2
DeGruttola, V.3
D'Aquila, R.T.4
Eron, J.J.5
Sommadossi, J.P.6
Currier, J.S.7
Smeaton, L.8
Frank, I.9
Caliendo, A.M.10
Gerber, J.G.11
Tung, R.12
Kuritzkes, D.R.13
-
106
-
-
0033946694
-
Absence of zidovudine resistance in antiretroviral-naive patients following zidovudine/lamivudine/protease inhibitor combination therapy: Virological evaluation of the AVANTI 2 and AVANTI 3 studies
-
Maguire M, Gartland M, Moore S, Hill A, Tisdale M, Harrigan R & Kleim JP. Absence of zidovudine resistance in antiretroviral-naive patients following zidovudine/lamivudine/protease inhibitor combination therapy: virological evaluation of the AVANTI 2 and AVANTI 3 studies. AIDS 2000; 14:1195-1201.
-
(2000)
AIDS
, vol.14
, pp. 1195-1201
-
-
Maguire, M.1
Gartland, M.2
Moore, S.3
Hill, A.4
Tisdale, M.5
Harrigan, R.6
Kleim, J.P.7
-
107
-
-
2642704250
-
Human immunodeficiency virus replication and genotypic resistance in blood and lymph nodes after a year of potent antiretroviral therapy
-
Gunthard HF, Wong JK, Ignacio CC, Guatelli JC, Riggs NL, Havlir DV & Richman DD. Human immunodeficiency virus replication and genotypic resistance in blood and lymph nodes after a year of potent antiretroviral therapy. Journal of Virology 1998; 72:2422-2428.
-
(1998)
Journal of Virology
, vol.72
, pp. 2422-2428
-
-
Gunthard, H.F.1
Wong, J.K.2
Ignacio, C.C.3
Guatelli, J.C.4
Riggs, N.L.5
Havlir, D.V.6
Richman, D.D.7
-
108
-
-
0037182766
-
Lopinavir-ritonavir versus nelfinavir for the initial treatment of HIV infection
-
Walmsley S, Bernstein B, King M, Arribas J, Beall G, Ruane P, Johnson M, Johnson D, Lalonde R, Japour A, Brun S & Sun E; M98-863 Study Team. Lopinavir-ritonavir versus nelfinavir for the initial treatment of HIV infection. New England Journal of Medicine 2002; 346:2039-2046.
-
(2002)
New England Journal of Medicine
, vol.346
, pp. 2039-2046
-
-
Walmsley, S.1
Bernstein, B.2
King, M.3
Arribas, J.4
Beall, G.5
Ruane, P.6
Johnson, M.7
Johnson, D.8
Lalonde, R.9
Japour, A.10
Brun, S.11
Sun, E.12
-
109
-
-
0346720608
-
ACTG 5095: A comparative study of 3 protease inhibitor-sparing antiretroviral regimens for the initial treatment of HIV infection
-
Abstract 41
-
Gulick RM, Ribaudo HJ, Shikuma CM, Lustgarten S, Meyer WA, Klingman K, Squires KE, Snyder S & Kuritzkes DR. ACTG 5095: A comparative study of 3 protease inhibitor-sparing antiretroviral regimens for the initial treatment of HIV infection. Antiviral Therapy 2003; 8(Suppl. 1):S194. Abstract 41.
-
(2003)
Antiviral Therapy
, vol.8
, Issue.SUPPL. 1
-
-
Gulick, R.M.1
Ribaudo, H.J.2
Shikuma, C.M.3
Lustgarten, S.4
Meyer, W.A.5
Klingman, K.6
Squires, K.E.7
Snyder, S.8
Kuritzkes, D.R.9
-
110
-
-
0037131342
-
The prevalence and determinants of the K65R mutation in HIV reverse transcriptase in tenofovir naive patients
-
July 7-12; Barcelona, Spain. Abstract TuPeB4600
-
Winston A, Mandalia S, Pillay D, Gazzard B & Pozniak A. The prevalence and determinants of the K65R mutation in HIV reverse transcriptase in tenofovir naive patients. Presented at: XIV International AIDS Conference; July 7-12 2002; Barcelona, Spain. Abstract TuPeB4600.
-
(2002)
XIV International AIDS Conference
-
-
Winston, A.1
Mandalia, S.2
Pillay, D.3
Gazzard, B.4
Pozniak, A.5
-
111
-
-
0142072954
-
Early virologic failure in a pilot study evaluating the efficacy of abacavir, lamivudine and tenofovir in treatment naive HIV-infected patients
-
Abstract 43
-
Farthing C, Khanlou H & Yeh V. Early virologic failure in a pilot study evaluating the efficacy of abacavir, lamivudine and tenofovir in treatment naive HIV-infected patients. Antiviral Therapy 2003; 8(Suppl. 1):S195. Abstract 43.
-
(2003)
Antiviral Therapy
, vol.8
, Issue.SUPPL. 1
-
-
Farthing, C.1
Khanlou, H.2
Yeh, V.3
-
112
-
-
0345007748
-
Early non-response to tenofovir DF (TDF) + abacavir (ABC) and lamivudine (3TC) in a randomized trial compared to efavirenz (EFV) + ABC and 3TC: ESS30009 unplanned interim analysis
-
September 14-17; Chicago, Ill., USA. Abstract LB-1722A
-
Gallant JE, Rodriguez AE, Weinberg W et al. for the ESS30009 Study Team. Early non-response to tenofovir DF (TDF) + abacavir (ABC) and lamivudine (3TC) in a randomized trial compared to efavirenz (EFV) + ABC and 3TC: ESS30009 unplanned interim analysis. Presented at: 43rd Interscience Conference on Antimicrobial Agents & Chemotherapy. September 14-17 2003; Chicago, Ill., USA. Abstract LB-1722A.
-
(2003)
43rd Interscience Conference on Antimicrobial Agents & Chemotherapy
-
-
Gallant, J.E.1
Rodriguez, A.E.2
Weinberg, W.3
-
113
-
-
0030768138
-
Attenuated replication of human immunodeficiency virus type 1 with a didanosine-selected reverse transcriptase mutation
-
Sharma PL & Crumpacker CS. Attenuated replication of human immunodeficiency virus type 1 with a didanosine-selected reverse transcriptase mutation. Journal of Virology 1997; 71:8846-8851.
-
(1997)
Journal of Virology
, vol.71
, pp. 8846-8851
-
-
Sharma, P.L.1
Crumpacker, C.S.2
-
114
-
-
0035864943
-
Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia
-
Deeks SG, Wrin T, Liegler T, Hoh R, Hayden M, Barbour JD, Hellmann NS, Petropoulos CJ, McCune JM, Hellerstein MK & Grant RM. Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia. New England Journal of Medicine 2001; 344:472-480.
-
(2001)
New England Journal of Medicine
, vol.344
, pp. 472-480
-
-
Deeks, S.G.1
Wrin, T.2
Liegler, T.3
Hoh, R.4
Hayden, M.5
Barbour, J.D.6
Hellmann, N.S.7
Petropoulos, C.J.8
McCune, J.M.9
Hellerstein, M.K.10
Grant, R.M.11
-
115
-
-
0002451331
-
HIV-specific cellular immunity and partial control of drug-resistant vs wild-type viremia
-
February 24-28; Seattle, Wash., USA. Abstract 108
-
Deeks SG, Sinclair E, Harris JM et al. HIV-specific cellular immunity and partial control of drug-resistant vs wild-type viremia. Presented at: 9th Conference on Retroviruses & Opportunistic Infections; February 24-28 2002; Seattle, Wash., USA. Abstract 108.
-
(2002)
9th Conference on Retroviruses & Opportunistic Infections
-
-
Deeks, S.G.1
Sinclair, E.2
Harris, J.M.3
-
116
-
-
0034081772
-
Patterns of resistance mutations selected by treatment of human immunodeficiency virus type 1 infection with zidovudine, didanosine, and nevirapine
-
Hanna GJ, Johnson VA, Kuritzkes DR, Richman DD, Brown AJ, Savara AV, Hazelwood JD & D'Aquila RT. Patterns of resistance mutations selected by treatment of human immunodeficiency virus type 1 infection with zidovudine, didanosine, and nevirapine. Journal of Infectious Diseases 2000; 181:904-911.
-
(2000)
Journal of Infectious Diseases
, vol.181
, pp. 904-911
-
-
Hanna, G.J.1
Johnson, V.A.2
Kuritzkes, D.R.3
Richman, D.D.4
Brown, A.J.5
Savara, A.V.6
Hazelwood, J.D.7
D'Aquila, R.T.8
-
117
-
-
0003077314
-
Effect of baseline nucleoside-associated resistance on response to tenofovir DF (TDF) therapy: Integrated analyses of studies 902 and 907
-
February 24-28 2002; Seattle, Wash., USA. Abstract 43
-
Miller MD, Margot NA & Lu B. Effect of baseline nucleoside-associated resistance on response to tenofovir DF (TDF) therapy: integrated analyses of studies 902 and 907. Presented at: 9th Conference on Retroviruses & Opportunistic Infections; February 24-28 2002; Seattle, Wash., USA. Abstract 43.
-
(2002)
9th Conference on Retroviruses & Opportunistic Infections
-
-
Miller, M.D.1
Margot, N.A.2
Lu, B.3
-
118
-
-
0032701542
-
Mutation patterns of the reverse transcriptase and protease genes in human immunodeficiency virus type 1-infected patients undergoing combination therapy: Survey of 787 sequences
-
Yahi N, Tamalet C, Tourres C, Tivoli N, Ariasi F, Volot F, Gastaut JA, Gallais H, Moreau J & Fantini J. Mutation patterns of the reverse transcriptase and protease genes in human immunodeficiency virus type 1-infected patients undergoing combination therapy: survey of 787 sequences. Journal of Clinical Microbiology 1999; 37:4099-4106.
-
(1999)
Journal of Clinical Microbiology
, vol.37
, pp. 4099-4106
-
-
Yahi, N.1
Tamalet, C.2
Tourres, C.3
Tivoli, N.4
Ariasi, F.5
Volot, F.6
Gastaut, J.A.7
Gallais, H.8
Moreau, J.9
Fantini, J.10
-
119
-
-
0346720609
-
Prediction of NRTI Options by Linking Reverse Transcriptase Genotype to Phenotypic Breakpoints
-
February 10-14; Boston, Mass., USA. Abstract 586
-
Lanier ER, Irlbeck D, Ross L, Gerondelis P, Underwood M, Parkin N, Chappey C & St Clair M. Prediction of NRTI Options by Linking Reverse Transcriptase Genotype to Phenotypic Breakpoints. Presented at: 10th Conference on Retroviruses & Opportunistic Infections; February 10-14 2003; Boston, Mass., USA. Abstract 586.
-
(2003)
10th Conference on Retroviruses & Opportunistic Infections
-
-
Lanier, E.R.1
Irlbeck, D.2
Ross, L.3
Gerondelis, P.4
Underwood, M.5
Parkin, N.6
Chappey, C.7
St. Clair, M.8
-
121
-
-
0034051154
-
Strategies for long-term success in the treatment of HIV infection
-
Gallant J. Strategies for long-term success in the treatment of HIV infection. Journal of the American Medical Association 2000; 283:1329-1334.
-
(2000)
Journal of the American Medical Association
, vol.283
, pp. 1329-1334
-
-
Gallant, J.1
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