메뉴 건너뛰기




Volumn 45, Issue 6, 2001, Pages 1836-1842

Genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 variants with insertions or deletions in the reverse transcriptase (RT): Multicenter study of patients treated with RT inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; AMPRENAVIR; DELAVIRDINE; DIDANOSINE; HYDROXYUREA; INDINAVIR; LAMIVUDINE; NELFINAVIR; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; STAVUDINE; ZALCITABINE; ZIDOVUDINE;

EID: 0034999828     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.45.6.1836-1842.2001     Document Type: Article
Times cited : (69)

References (31)
  • 3
    • 0027965903 scopus 로고
    • HIV-1 reverse transcription: A termination step at the centre of the genome
    • Charneau, P., G. Mirambeau, P. Roux, S. Paulous, H. Bue, and F. Clavel. 1994. HIV-1 reverse transcription: a termination step at the centre of the genome. J. Mol. Biol. 241:651-662.
    • (1994) J. Mol. Biol. , vol.241 , pp. 651-662
    • Charneau, P.1    Mirambeau, G.2    Roux, P.3    Paulous, S.4    Bue, H.5    Clavel, F.6
  • 4
    • 0002658306 scopus 로고
    • The median-effect principle and the combination index for quantitation of synergism and antagonism
    • T.-C. Chou and J. Rideout (ed.), Academic Press, New York, N.Y.
    • Chou, T.-C. 1991. The median-effect principle and the combination index for quantitation of synergism and antagonism. P. 61-102. In T.-C. Chou and J. Rideout (ed.), Synergism and antagonism in chemotherapy. Academic Press, New York, N.Y.
    • (1991) Synergism and Antagonism in Chemotherapy , pp. 61-102
    • Chou, T.-C.1
  • 6
    • 0002310279 scopus 로고    scopus 로고
    • Frequency of stavudine and didanosine resistance among a large number of randomly selected HIV-1 isolates
    • Colonno, R. J., Y. T. Wachtfogel, K. Hertogs, and B. A. Larder. 2000. Frequency of stavudine and didanosine resistance among a large number of randomly selected HIV-1 isolates. Antivir. Ther. 5:85.
    • (2000) Antivir. Ther. , vol.5 , pp. 85
    • Colonno, R.J.1    Wachtfogel, Y.T.2    Hertogs, K.3    Larder, B.A.4
  • 7
    • 0030840407 scopus 로고    scopus 로고
    • Mutations in the pol gene of human immunodeficiency virus type 1 in infected patients receiving didanosine and hydroxyurea conihination therapy
    • De Antoni, A., J. Foli, J. Lisziewicz, and F. Lori. 1997. Mutations in the pol gene of human immunodeficiency virus type 1 in infected patients receiving didanosine and hydroxyurea conihination therapy. J. Infect. Dis. 176:899-903.
    • (1997) J. Infect. Dis. , vol.176 , pp. 899-903
    • De Antoni, A.1    Foli, J.2    Lisziewicz, J.3    Lori, F.4
  • 8
    • 0033552832 scopus 로고    scopus 로고
    • Insertion of two amino acids combined with changes in reverse transcriptase containing tyrosine-215 of HIV-1 resistant to multiple nucleoside analogs
    • de Jong, J. J., J. Goudsmit, V. V. Lukashov, M. E. Hillebrand, E. Baan, R. Huismans, S. A. Danner, J. H. Ten Veen, F. De Wolf, and S. Jurrians. 1999. Insertion of two amino acids combined with changes in reverse transcriptase containing tyrosine-215 of HIV-1 resistant to multiple nucleoside analogs. AIDS 13:75-80.
    • (1999) AIDS , vol.13 , pp. 75-80
    • De Jong, J.J.1    Goudsmit, J.2    Lukashov, V.V.3    Hillebrand, M.E.4    Baan, E.5    Huismans, R.6    Danner, S.A.7    Ten Veen, J.H.8    De Wolf, F.9    Jurrians, S.10
  • 12
    • 0030048748 scopus 로고    scopus 로고
    • Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy
    • Iversen, A. K. N., R. W. Shafer, K. Wehrly, M. A. Winters, J. I. Mullins, B. Chesebro, and T. C. Merigan. 1996. Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy. J. Virol. 70:1086-1090.
    • (1996) J. Virol. , vol.70 , pp. 1086-1090
    • Iversen, A.K.N.1    Shafer, R.W.2    Wehrly, K.3    Winters, M.A.4    Mullins, J.I.5    Chesebro, B.6    Merigan, T.C.7
  • 14
    • 0026565278 scopus 로고
    • A novel fifth mutation in HIV-1 reverse transcriptase contributes to the development of high-level resistance to zidovudine
    • Kellam, P., C. A. B. Boucher, and B. A. Larder. 1992. A novel fifth mutation in HIV-1 reverse transcriptase contributes to the development of high-level resistance to zidovudine. Proc. Natl. Acad. Sci. USA 80:1934-1938.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 1934-1938
    • Kellam, P.1    Boucher, C.A.B.2    Larder, B.A.3
  • 15
    • 0024310253 scopus 로고
    • Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)
    • Larder, B. A., and S. D. Kemp. 1989. Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT). Science 246: 1155-1158.
    • (1989) Science , vol.246 , pp. 1155-1158
    • Larder, B.A.1    Kemp, S.D.2
  • 16
    • 0026036042 scopus 로고
    • Zidovudine resistance predicted by direct detection of mutations in DNA from HIV-infected lymphocytes
    • Larder, B. A., P. Kellam, and S. D. Kemp. 1991. Zidovudine resistance predicted by direct detection of mutations in DNA from HIV-infected lymphocytes. AIDS 5:137-144.
    • (1991) AIDS , vol.5 , pp. 137-144
    • Larder, B.A.1    Kellam, P.2    Kemp, S.D.3
  • 20
    • 0032750954 scopus 로고    scopus 로고
    • Analysis of human immunodeficiency virus type 1 cross-resistance to protease inhibitors in patients failing on combination therapies using a rapid single-cycle recombinant virus assay
    • Race, E., E. Dam, V. Obry, S. Paulous, and F. Clavel. 1999. Analysis of human immunodeficiency virus type 1 cross-resistance to protease inhibitors in patients failing on combination therapies using a rapid single-cycle recombinant virus assay. AIDS 13:2061-2068.
    • (1999) AIDS , vol.13 , pp. 2061-2068
    • Race, E.1    Dam, E.2    Obry, V.3    Paulous, S.4    Clavel, F.5
  • 21
    • 0032724499 scopus 로고    scopus 로고
    • A novel genotype encoding a single amino acid insertion and five other substitutions between residues 64 and 74 of the HIV-1 reverse transcriptase confers high-level cross-resistance to nucleoside reverse transcriptase inhibitors
    • Rakik, A., M. Ait-Khaled, P. Griffin, D. A. Thomas, M. Tisdale, and J. P. Kleim for the abacavir CNA2007 International Study Group. 1999. A novel genotype encoding a single amino acid insertion and five other substitutions between residues 64 and 74 of the HIV-1 reverse transcriptase confers high-level cross-resistance to nucleoside reverse transcriptase inhibitors. J. Aquir. Immune Defic. Syndr. 22:139-145.
    • (1999) J. Aquir. Immune Defic. Syndr. , vol.22 , pp. 139-145
    • Rakik, A.1    Ait-Khaled, M.2    Griffin, P.3    Thomas, D.A.4    Tisdale, M.5    Kleim, J.P.6
  • 22
    • 0033502898 scopus 로고    scopus 로고
    • The reverse transcriptase codon 69 insertion is observed in nucleoside reverse transcriptase inhibitor-experienced HIV-1 infected individuals, including those without prior or concurrent zidovudine therapy
    • Ross, L., M. Johnson, N. Graham, M. Shaefer and M. St. Clair. 1999. The reverse transcriptase codon 69 insertion is observed in nucleoside reverse transcriptase inhibitor-experienced HIV-1 infected individuals, including those without prior or concurrent zidovudine therapy. J. Hum. Virol. 2:290-295.
    • (1999) J. Hum. Virol. , vol.2 , pp. 290-295
    • Ross, L.1    Johnson, M.2    Graham, N.3    Shaefer, M.4    St. Clair, M.5
  • 23
    • 0034083833 scopus 로고    scopus 로고
    • Mutations in retroviral genes associated with drug resistance: 2000-2001 update
    • Schinazi, R. F., B. A. Larder, and J. W. Mellors. 2000. Mutations in retroviral genes associated with drug resistance: 2000-2001 update. Int. Antivir. News 8:65-91.
    • (2000) Int. Antivir. News , vol.8 , pp. 65-91
    • Schinazi, R.F.1    Larder, B.A.2    Mellors, J.W.3
  • 26
    • 0032189068 scopus 로고    scopus 로고
    • Stable rearrangements of the β3-β4 hairpin loop of HIV-1 reverse transcriptase in plasma viruses from patients receiving combination therapy
    • Tamalet, C., J. Izopet, N. Koch, J. Fantini, and N. Yahi. 1998. Stable rearrangements of the β3-β4 hairpin loop of HIV-1 reverse transcriptase in plasma viruses from patients receiving combination therapy. AIDS 12:F161-F166.
    • (1998) AIDS , vol.12
    • Tamalet, C.1    Izopet, J.2    Koch, N.3    Fantini, J.4    Yahi, N.5
  • 27
    • 0034630898 scopus 로고    scopus 로고
    • Multidrug resistance genotypes (insertions in the beta3-beta4 finger subdomain and MDR mutations) of HIV-1 reverse transcriptase from extensively treated patients: Incidence and association with other resistance mutations
    • Tamalet, C., N. Yahi, C. Tourres, P. Colson, A. M. Quinson, I. Poizot-Martin, C. Dhiver, and J. Fantini. 2000. Multidrug resistance genotypes (insertions in the beta3-beta4 finger subdomain and MDR mutations) of HIV-1 reverse transcriptase from extensively treated patients: incidence and association with other resistance mutations. Virology 270:310-316.
    • (2000) Virology , vol.270 , pp. 310-316
    • Tamalet, C.1    Yahi, N.2    Tourres, C.3    Colson, P.4    Quinson, A.M.5    Poizot-Martin, I.6    Dhiver, C.7    Fantini, J.8
  • 29
    • 0032533207 scopus 로고    scopus 로고
    • A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors
    • Winters, M. A., K. I. Cooley, Y. A. Girard, D. J. Levee, H. Hamdan, R. W. Shafer, D. A. Katzenstein, and T. C. Merigan. 1998. A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors. J. Clin. Investig. 102: 1769-1775.
    • (1998) J. Clin. Investig. , vol.102 , pp. 1769-1775
    • Winters, M.A.1    Cooley, K.I.2    Girard, Y.A.3    Levee, D.J.4    Hamdan, H.5    Shafer, R.W.6    Katzenstein, D.A.7    Merigan, T.C.8
  • 30
    • 0033760936 scopus 로고    scopus 로고
    • Genotypic, phenotypic, and modeling studies of a deletion in the β3-β4 region of the human immunodeficiency virus type 1 reverse transeriptase gene that is associated with resistance to nucleoside reverse transcriptase inhibitors
    • Winters, M. A., K. L. Coolley, P. Cheng, Y. A. Girard, H. Hamdan, L. C. Kovari, and T. C. Merigan. 2000. Genotypic, phenotypic, and modeling studies of a deletion in the β3-β4 region of the human immunodeficiency virus type 1 reverse transeriptase gene that is associated with resistance to nucleoside reverse transcriptase inhibitors. J. Virol. 74:10707-10713.
    • (2000) J. Virol. , vol.74 , pp. 10707-10713
    • Winters, M.A.1    Coolley, K.L.2    Cheng, P.3    Girard, Y.A.4    Hamdan, H.5    Kovari, L.C.6    Merigan, T.C.7
  • 31
    • 0031946007 scopus 로고    scopus 로고
    • Loss of viral fitness associated with multiple Gag and Gag-Pol processing defects in human immunodeficiency virus type 1 variants selected for resistance to prolease inhibitors in vivo
    • Zennou, V., F. Mammano, S. Paulous, D. Mathez, and F. Clavel. 1998. Loss of viral fitness associated with multiple Gag and Gag-Pol processing defects in human immunodeficiency virus type 1 variants selected for resistance to prolease inhibitors in vivo. J. Virol. 72:3300-3306.
    • (1998) J. Virol. , vol.72 , pp. 3300-3306
    • Zennou, V.1    Mammano, F.2    Paulous, S.3    Mathez, D.4    Clavel, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.