An unstable liaison

Science

Volumn 300, Issue 5618, 2003, Pages 442-443

  Lengauer, Christoph ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE; GENOMIC DNA; HISTONE; PROTEIN P53; DNA (CYTOSINE 5 ) METHYLTRANSFERASE 1; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B;

INSTABILITY;

ADENOMATOUS POLYP; ANIMAL MODEL; CHROMATIN STRUCTURE; COLON CANCER; COLON CARCINOGENESIS; DNA METHYLATION; DNMT3B GENE; GENE; GENE LOCUS; HETEROZYGOSITY LOSS; INTESTINE CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; TUMOR CELL; TUMOR SUPPRESSOR GENE; ALLELE; ANIMAL; CHROMOSOME; CHROMOSOME ABERRATION; COLORECTAL TUMOR; DNA REPAIR; GENE SILENCING; GENETIC RECOMBINATION; GENETICS; HUMAN; METABOLISM; MUTATION; NEOPLASM; NOTE; PHYSIOLOGY; SARCOMA; SOFT TISSUE TUMOR; T CELL LYMPHOMA;

ANIMALIA;

ALLELES; ANIMALS; CHROMOSOME ABERRATIONS; CHROMOSOMES; COLORECTAL NEOPLASMS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA REPAIR; GENE SILENCING; GENES, NEUROFIBROMATOSIS 1; GENES, P53; HUMANS; LOSS OF HETEROZYGOSITY; LYMPHOMA, T-CELL; MICE; MUTATION; NEOPLASMS; RECOMBINATION, GENETIC; SARCOMA; SOFT TISSUE NEOPLASMS;

EID: 0037453509     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1084468     Document Type: Short Survey

References (21)

1. P. A. Jones, S. B. Baylin, Nature Rev. Genet. 3, 415 (2002).
2. A. P. Feinberg, B. Vogelstein, Nature 301, 89 (1983).
3. T. L. Kautiainen, P. A. Jones, J. Biol. Chem. 261, 1594 (1986).
4. A. Eden et al., Science 300, 455 (2003).
5. F. Gaudet et al., Science 300, 489 (2003).
6. M. Ehrlich, Oncogene 21, 5400 (2002).
7. P. Laird et al., Cell 81, 197 (1995).
8. B. N. Trinh et al., Mol Cell. Biol. 22, 2906 (2002).
9. C. Lengauer et al., Nature 396, 643 (1998).
10. Proc. Natl. Acad. Sci. U.S.A. 94, 2545 (1997).
11. G.-L. Xu et al., Nature 402, 187 (1999).
12. R. Z. Chen et al., Nature 395, 89 (1998).
13. E. Li et al., Cell 69, 915 (1992).
14. K. S. Vogel et al., Science 286, 2176 (1999).
15. A. H. Peters et al., Cell 107, 323 (2001).
16. R. Jaenisch, personal communication.
17. I. Rhee et al., Nature 404, 1003 (2000).
18. I. Rhee et al., Nature 416, 552 (2002).
19. A. R. Karpf, D. A. Jones, Oncogene 21, 5496 (2002).
20. D. P. Cahill et al., Trends Cell Biol. 9, M57 (1999).
21. I thank H. Rajagopalan and B. Vogelstein for their helpful comments.