메뉴 건너뛰기




Volumn 313, Issue 2, 2004, Pages 437-441

Raptor, a binding partner of target of rapamycin

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BINDING PROTEIN; REGULATORY ASSOCIATED PROTEIN OF MAMMALIAN TARGET OF RAPAMYCIN; TARGET OF RAPAMYCIN KINASE; TUBERIN; UNCLASSIFIED DRUG;

EID: 0346366446     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.07.018     Document Type: Conference Paper
Times cited : (73)

References (35)
  • 1
    • 0027311858 scopus 로고
    • Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression
    • Kunz J., Henriquez R., Schneider U., Deuter Reinhard M., Movva N.R., Hall M.N. Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression. Cell. 73:1993;585-596.
    • (1993) Cell , vol.73 , pp. 585-596
    • Kunz, J.1    Henriquez, R.2    Schneider, U.3    Deuter Reinhard, M.4    Movva, N.R.5    Hall, M.N.6
  • 3
    • 0034644525 scopus 로고    scopus 로고
    • TOR, a central controller of cell growth
    • Schmelzle T., Hall M.N. TOR, a central controller of cell growth. Cell. 103:2000;253-262.
    • (2000) Cell , vol.103 , pp. 253-262
    • Schmelzle, T.1    Hall, M.N.2
  • 4
    • 0029095931 scopus 로고
    • Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway
    • Lin T.A., Kong X., Saltiel A.R., Blackshear P.J., Lawrence J.C. Jr. Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway. J. Biol. Chem. 270:1995;18531-18538.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18531-18538
    • Lin, T.A.1    Kong, X.2    Saltiel, A.R.3    Blackshear, P.J.4    Lawrence, J.C.Jr.5
  • 5
    • 0026759874 scopus 로고
    • Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase
    • Price D.J., Grove J.R., Calvo V., Avruch J., Bierer B.E. Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. Science. 257:1992;973-977.
    • (1992) Science , vol.257 , pp. 973-977
    • Price, D.J.1    Grove, J.R.2    Calvo, V.3    Avruch, J.4    Bierer, B.E.5
  • 8
    • 0028800996 scopus 로고
    • PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints
    • Keith C.T., Schreiber S.L. PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints. Science. 270:1995;50-51.
    • (1995) Science , vol.270 , pp. 50-51
    • Keith, C.T.1    Schreiber, S.L.2
  • 9
    • 0035225023 scopus 로고    scopus 로고
    • The p70 S6 kinase integrates nutrient and growth signals to control translational capacity
    • Avruch J., Belham C., Weng Q., Hara K., Yonezawa K. The p70 S6 kinase integrates nutrient and growth signals to control translational capacity. Prog. Mol. Subcell. Biol. 26:2001;115-154.
    • (2001) Prog. Mol. Subcell. Biol. , vol.26 , pp. 115-154
    • Avruch, J.1    Belham, C.2    Weng, Q.3    Hara, K.4    Yonezawa, K.5
  • 11
    • 0000831271 scopus 로고    scopus 로고
    • ′ Cap-binding protein eIF4E and control of cell growth
    • W.B. Hershey, M.B. Mathews, & N. Sonenberg. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory
    • ′ Cap-binding protein eIF4E and control of cell growth Hershey W.B., Mathews M.B., Sonenberg N. Translational Control. 1996;245-270 Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
    • (1996) Translational Control , pp. 245-270
    • Sonenberg, N.1
  • 12
    • 0032486268 scopus 로고    scopus 로고
    • Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism
    • Hara K., Yonezawa K., Weng Q.P., Kozlowski M.T., Belham C., Avruch J. Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism. J. Biol. Chem. 273:1998;14484-14494.
    • (1998) J. Biol. Chem. , vol.273 , pp. 14484-14494
    • Hara, K.1    Yonezawa, K.2    Weng, Q.P.3    Kozlowski, M.T.4    Belham, C.5    Avruch, J.6
  • 14
    • 0032528917 scopus 로고    scopus 로고
    • Amino acid availability regulates p70 S6 kinase and multiple translation factors
    • Wang X., Campbell L.E., Miller C.M., Proud C.G. Amino acid availability regulates p70 S6 kinase and multiple translation factors. Biochem. J. 334:1998;261-267.
    • (1998) Biochem. J. , vol.334 , pp. 261-267
    • Wang, X.1    Campbell, L.E.2    Miller, C.M.3    Proud, C.G.4
  • 15
    • 0034312279 scopus 로고    scopus 로고
    • Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin
    • Oldham S., Montagne J., Radimerski T., Thomas G., Hafen E. Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin. Genes Dev. 14:2000;2689-2694.
    • (2000) Genes Dev. , vol.14 , pp. 2689-2694
    • Oldham, S.1    Montagne, J.2    Radimerski, T.3    Thomas, G.4    Hafen, E.5
  • 16
    • 0034312315 scopus 로고    scopus 로고
    • Regulation of cellular growth by the Drosophila target of rapamycin dTOR
    • Zhang H., Stallock J.P., Ng J.C., Reinhard C., Neufeld T.P. Regulation of cellular growth by the Drosophila target of rapamycin dTOR. Genes Dev. 14:2000;2712-2724.
    • (2000) Genes Dev. , vol.14 , pp. 2712-2724
    • Zhang, H.1    Stallock, J.P.2    Ng, J.C.3    Reinhard, C.4    Neufeld, T.P.5
  • 20
    • 0032514924 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region
    • Gout I., Minami T., Hara K., Tsujishita Y., Filonenko V., Waterfield M.D., Yonezawa K. Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region. J. Biol. Chem. 273:1998;30061-30064.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30061-30064
    • Gout, I.1    Minami, T.2    Hara, K.3    Tsujishita, Y.4    Filonenko, V.5    Waterfield, M.D.6    Yonezawa, K.7
  • 21
    • 0033607531 scopus 로고    scopus 로고
    • Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro
    • Isotani S., Hara K., Tokunaga C., Inoue H., Avruch J., Yonezawa K. Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro. J. Biol. Chem. 274:1999;34493-34498.
    • (1999) J. Biol. Chem. , vol.274 , pp. 34493-34498
    • Isotani, S.1    Hara, K.2    Tokunaga, C.3    Inoue, H.4    Avruch, J.5    Yonezawa, K.6
  • 23
    • 0033983556 scopus 로고    scopus 로고
    • Novel WD-repeat protein Mip1p facilitates function of the meiotic regulator Mei2p in fission yeast
    • Shinozaki-Yabana S., Watanabe Y., Yamamoto M. Novel WD-repeat protein Mip1p facilitates function of the meiotic regulator Mei2p in fission yeast. Mol. Cell. Biol. 20:2000;1234-1242.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1234-1242
    • Shinozaki-Yabana, S.1    Watanabe, Y.2    Yamamoto, M.3
  • 27
    • 0037623417 scopus 로고    scopus 로고
    • GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR
    • Kim D.H., Sarbassov D.D., Ali S.M., Latek R.R., Guntur K.V., Erdjument-Bromage H., Tempst P., Sabatini D.M. GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Mol. Cell. 11:2003;895-904.
    • (2003) Mol. Cell , vol.11 , pp. 895-904
    • Kim, D.H.1    Sarbassov, D.D.2    Ali, S.M.3    Latek, R.R.4    Guntur, K.V.5    Erdjument-Bromage, H.6    Tempst, P.7    Sabatini, D.M.8
  • 28
    • 0037117409 scopus 로고    scopus 로고
    • Identification of a conserved motif required for mTOR signaling
    • Schalm S.S., Blenis J. Identification of a conserved motif required for mTOR signaling. Curr. Biol. 12:2002;632-639.
    • (2002) Curr. Biol. , vol.12 , pp. 632-639
    • Schalm, S.S.1    Blenis, J.2
  • 29
    • 0037507252 scopus 로고    scopus 로고
    • The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif
    • Nojima H., Tokunaga C., Eguchi S., Oshiro N., Hidayat S., Yoshino K., Hara K., Tanaka N., Avruch J., Yonezawa K. The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif. J. Biol. Chem. 278:2003;15461-15464.
    • (2003) J. Biol. Chem. , vol.278 , pp. 15461-15464
    • Nojima, H.1    Tokunaga, C.2    Eguchi, S.3    Oshiro, N.4    Hidayat, S.5    Yoshino, K.6    Hara, K.7    Tanaka, N.8    Avruch, J.9    Yonezawa, K.10
  • 30
    • 0037718389 scopus 로고    scopus 로고
    • TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function
    • Schalm S.S., Fingar D.C., Sabatini D.M., Blenis J. TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function. Curr. Biol. 13:2003;797-806.
    • (2003) Curr. Biol. , vol.13 , pp. 797-806
    • Schalm, S.S.1    Fingar, D.C.2    Sabatini, D.M.3    Blenis, J.4
  • 31
    • 0038482156 scopus 로고    scopus 로고
    • Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor
    • Choi K.M., McMahon L.P., Lawrence J.J. Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor. J. Biol. Chem. 278:2003;19667-19673.
    • (2003) J. Biol. Chem. , vol.278 , pp. 19667-19673
    • Choi, K.M.1    McMahon, L.P.2    Lawrence, J.J.3
  • 32
    • 0142071830 scopus 로고    scopus 로고
    • Target of rapamycin (TOR)-signaling and RAIP motifs play distinct roles in the mammalian TOR-dependent phosphorylation of initiation factor 4E-binding protein 1
    • Beugnet A., Wang X., Proud C.G. Target of rapamycin (TOR)-signaling and RAIP motifs play distinct roles in the mammalian TOR-dependent phosphorylation of initiation factor 4E-binding protein 1. J. Biol. Chem. 278:2003;40717-40722.
    • (2003) J. Biol. Chem. , vol.278 , pp. 40717-40722
    • Beugnet, A.1    Wang, X.2    Proud, C.G.3
  • 33
    • 0037137380 scopus 로고    scopus 로고
    • Growth signaling: TSC takes its place
    • Marygold S.J., Leevers S.J. Growth signaling: TSC takes its place. Curr. Biol. 12:2002;R785-R787.
    • (2002) Curr. Biol. , vol.12
    • Marygold, S.J.1    Leevers, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.