메뉴 건너뛰기




Volumn 42, Issue 7, 2003, Pages 660-671

Oncolytic Herpes Viruses as a Potential Mechanism for Cancer Therapy

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; DISEASE CONTROL; GENES; GENETIC ENGINEERING; ONCOGENIC VIRUSES; ONCOLOGY; TISSUE CULTURE;

EID: 0345449049     PISSN: 0284186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/0284186031000518     Document Type: Review
Times cited : (26)

References (185)
  • 1
    • 0001511115 scopus 로고
    • The influence of complicating diseases upon leukaemia
    • Dock G. The influence of complicating diseases upon leukaemia. Am J Med Sci 1904; 127: 563-92.
    • (1904) Am J Med Sci , vol.127 , pp. 563-592
    • Dock, G.1
  • 2
    • 0014934866 scopus 로고
    • Viruses in the treatment of cancer
    • Webb HE, Smith CE. Viruses in the treatment of cancer. Lancet 1970; 1: 1206-8.
    • (1970) Lancet , vol.1 , pp. 1206-1208
    • Webb, H.E.1    Smith, C.E.2
  • 3
    • 0004983276 scopus 로고
    • Effects of viruses on tumors
    • Moore AE. Effects of viruses on tumors. Ann Rev Microbiol 1954; 8: 393-410.
    • (1954) Ann Rev Microbiol , vol.8 , pp. 393-410
    • Moore, A.E.1
  • 4
    • 77049281450 scopus 로고
    • Studies on the use of viruses in the treatment of carcinoma of the cervix
    • Smith RRHRJ, Rowe WP, Schatten WE, Thomas LB. Studies on the use of viruses in the treatment of carcinoma of the cervix. Cancer 1956; 9: 1211-8.
    • (1956) Cancer , vol.9 , pp. 1211-1218
    • Smith, R.R.H.R.J.1    Rowe, W.P.2    Schatten, W.E.3    Thomas, L.B.4
  • 5
    • 0000343064 scopus 로고
    • Present status of oncolytic virus studies
    • Southam C. Present status of oncolytic virus studies. Trans NY Acad Sci 1960; 22: 657-73.
    • (1960) Trans NY Acad Sci , vol.22 , pp. 657-673
    • Southam, C.1
  • 6
    • 0034022622 scopus 로고    scopus 로고
    • Gene delivery from replication-selective viruses: Arming guided missiles in the war against cancer
    • Hermiston T. Gene delivery from replication-selective viruses: arming guided missiles in the war against cancer. J Clin Invest 2000; 105: 1169-72.
    • (2000) J Clin Invest , vol.105 , pp. 1169-1172
    • Hermiston, T.1
  • 7
    • 0028775663 scopus 로고
    • Viruses as oncolytic agents: A new age for 'therapeutic' viruses?
    • Kenney S, Pagano JS. Viruses as oncolytic agents: a new age for 'therapeutic' viruses? J Natl Cancer Inst 1994; 86: 1185-6.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1185-1186
    • Kenney, S.1    Pagano, J.S.2
  • 8
    • 0034927057 scopus 로고    scopus 로고
    • Replication-selective virotherapy for cancer: Biological principles, risk management and future directions
    • Kirn D, Martuza RL, Zwiebel J. Replication-selective virotherapy for cancer: biological principles, risk management and future directions. Nat Med 2001; 7: 781-7.
    • (2001) Nat Med , vol.7 , pp. 781-787
    • Kirn, D.1    Martuza, R.L.2    Zwiebel, J.3
  • 9
    • 0034128881 scopus 로고    scopus 로고
    • Replication-selective microbiological agents: Fighting cancer with targeted germ warfare
    • Kirn DH. Replication-selective microbiological agents: fighting cancer with targeted germ warfare. J Clin Invest 2000; 105: 837-9.
    • (2000) J Clin Invest , vol.105 , pp. 837-839
    • Kirn, D.H.1
  • 10
    • 78651190570 scopus 로고
    • Newcastle disease virus as an antineoplastic agent
    • Cassel WAG. Newcastle disease virus as an antineoplastic agent. Cancer 1965; 18: 863-8.
    • (1965) Cancer , vol.18 , pp. 863-868
    • Cassel, W.A.G.1
  • 11
    • 0028081158 scopus 로고
    • Complete regression of human fibrosarcoma xenografts after local Newcastle disease virus therapy
    • Lorence RM, Katubig BB, Reichard KW, et al. Complete regression of human fibrosarcoma xenografts after local Newcastle disease virus therapy. Cancer Res 1994; 54: 6017-21.
    • (1994) Cancer Res , vol.54 , pp. 6017-6021
    • Lorence, R.M.1    Katubig, B.B.2    Reichard, K.W.3
  • 12
    • 0027980233 scopus 로고
    • Complete regression of human neuroblastoma xenografts in athymic mice after local Newcastle disease virus therapy
    • Lorence RM, Reichard KW, Katubig BB, et al. Complete regression of human neuroblastoma xenografts in athymic mice after local Newcastle disease virus therapy. J Natl Cancer Inst 1994; 86: 1228-33.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1228-1233
    • Lorence, R.M.1    Reichard, K.W.2    Katubig, B.B.3
  • 13
    • 0036569510 scopus 로고    scopus 로고
    • Phase I trial of intravenous administration of PV701, an oncolytic virus, in patients with advanced solid cancers
    • Pecora AL, Rizvi N, Cohen GI, et al. Phase I trial of intravenous administration of PV701, an oncolytic virus, in patients with advanced solid cancers. J Clin Oncol 2002; 20: 2251-66.
    • (2002) J Clin Oncol , vol.20 , pp. 2251-2266
    • Pecora, A.L.1    Rizvi, N.2    Cohen, G.I.3
  • 14
    • 0026751242 scopus 로고
    • Newcastle disease virus selectively kills human tumor cells
    • Richard KW, Lorence RM, Cascino CJ, et al. Newcastle disease virus selectively kills human tumor cells. J Surg Res 1992; 52: 448-53.
    • (1992) J Surg Res , vol.52 , pp. 448-453
    • Richard, K.W.1    Lorence, R.M.2    Cascino, C.J.3
  • 15
    • 0032515141 scopus 로고    scopus 로고
    • Reovirus therapy of tumors with activated Ras pathway
    • Coffey MC, Strong JE, Forsyth PA, Lee PW. Reovirus therapy of tumors with activated Ras pathway. Science 1998; 282: 1332-4.
    • (1998) Science , vol.282 , pp. 1332-1334
    • Coffey, M.C.1    Strong, J.E.2    Forsyth, P.A.3    Lee, P.W.4
  • 16
    • 0015233149 scopus 로고
    • Measles and leukaemia
    • Gross S. Measles and leukaemia. Lancet 1971; 1: 397-8.
    • (1971) Lancet , vol.1 , pp. 397-398
    • Gross, S.1
  • 17
    • 0016358317 scopus 로고
    • Treatment of human cancer with mumps virus
    • Asada T. Treatment of human cancer with mumps virus. Cancer 1974; 34: 1907-28.
    • (1974) Cancer , vol.34 , pp. 1907-1928
    • Asada, T.1
  • 19
    • 0034785561 scopus 로고    scopus 로고
    • Yaba-like disease virus: An alternative replicating poxvirus vector for cancer gene therapy
    • Hu Y, Lee J, McCart JA, et al. Yaba-like disease virus: an alternative replicating poxvirus vector for cancer gene therapy. J Virol 2001; 75: 10300-8.
    • (2001) J Virol , vol.75 , pp. 10300-10308
    • Hu, Y.1    Lee, J.2    McCart, J.A.3
  • 20
    • 0015043872 scopus 로고
    • Viruses as an aid to cancer therapy: Regression of solid and ascites tumors in rodents after treatment with bovine enterovirus
    • Taylor MW, Cordell B, Souhrada M, Prather S. Viruses as an aid to cancer therapy: regression of solid and ascites tumors in rodents after treatment with bovine enterovirus. Proc Natl Acad Sci USA 1971; 68: 836-40.
    • (1971) Proc Natl Acad Sci USA , vol.68 , pp. 836-840
    • Taylor, M.W.1    Cordell, B.2    Souhrada, M.3    Prather, S.4
  • 21
    • 0027818396 scopus 로고
    • A retroviral wild-type p53 expression vector penetrates human lung cancer spheroids and inhibits growth by inducing apoptosis
    • Fujiwara T, Grimm EA, Mukhopadhyay T, Cai DW, Owen-Schaub LB, Roth JA. A retroviral wild-type p53 expression vector penetrates human lung cancer spheroids and inhibits growth by inducing apoptosis. Cancer Res 1993; 53: 4129-33.
    • (1993) Cancer Res , vol.53 , pp. 4129-4133
    • Fujiwara, T.1    Grimm, E.A.2    Mukhopadhyay, T.3    Cai, D.W.4    Owen-Schaub, L.B.5    Roth, J.A.6
  • 22
    • 9544244796 scopus 로고    scopus 로고
    • Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer
    • Roth JA, Nguyen D, Lawrence DD, et al. Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer. Nat Med 1996; 2: 985-91.
    • (1996) Nat Med , vol.2 , pp. 985-991
    • Roth, J.A.1    Nguyen, D.2    Lawrence, D.D.3
  • 23
    • 0035175933 scopus 로고    scopus 로고
    • Systemic vector leakage and transgene expression by intratumorally injected recombinant adenovirus vectors
    • Lohr F, Huang Q, Hu K, Dewhirst MW, Li CY. Systemic vector leakage and transgene expression by intratumorally injected recombinant adenovirus vectors. Clin Cancer Res 2001; 7: 3625-8.
    • (2001) Clin Cancer Res , vol.7 , pp. 3625-3628
    • Lohr, F.1    Huang, Q.2    Hu, K.3    Dewhirst, M.W.4    Li, C.Y.5
  • 24
    • 0034438592 scopus 로고    scopus 로고
    • Adenoviral-mediated gene transfer to mouse salivary glands
    • Wang S, Baum BJ, Yamano S, et al. Adenoviral-mediated gene transfer to mouse salivary glands. J Dent Res 2000; 79: 701-8.
    • (2000) J Dent Res , vol.79 , pp. 701-708
    • Wang, S.1    Baum, B.J.2    Yamano, S.3
  • 25
    • 0034467640 scopus 로고    scopus 로고
    • Recombinant human adenovirus: Targeting to the human transferrin receptor improves gene transfer to brain microcapillary endothelium
    • Xia H, Anderson B, Mao Q, Davidson BL. Recombinant human adenovirus: targeting to the human transferrin receptor improves gene transfer to brain microcapillary endothelium. J Virol 2000; 74: 11359-66.
    • (2000) J Virol , vol.74 , pp. 11359-11366
    • Xia, H.1    Anderson, B.2    Mao, Q.3    Davidson, B.L.4
  • 26
    • 0037462590 scopus 로고    scopus 로고
    • Gene therapy. Seeking the cause of induced leukemias in X-SCID trial
    • Kaiser J. Gene therapy. Seeking the cause of induced leukemias in X-SCID trial. Science 2003; 299: 495.
    • (2003) Science , vol.299 , pp. 495
    • Kaiser, J.1
  • 27
    • 0037020112 scopus 로고    scopus 로고
    • Gene therapy a suspect in leukemia-like disease
    • Marshall E. Gene therapy a suspect in leukemia-like disease. Science 2002; 298: 34-5.
    • (2002) Science , vol.298 , pp. 34-35
    • Marshall, E.1
  • 28
    • 0037449534 scopus 로고    scopus 로고
    • Gene therapy. Second child in French trial is found to have leukemia
    • Marshall E. Gene therapy. Second child in French trial is found to have leukemia. Science 2003; 299: 320.
    • (2003) Science , vol.299 , pp. 320
    • Marshall, E.1
  • 29
    • 0035890773 scopus 로고    scopus 로고
    • A genetically engineered influenza A virus with ras-dependent oncolytic properties
    • Bergmann M, Romirer I, Sachet M, et al. A genetically engineered influenza A virus with ras-dependent oncolytic properties. Cancer Res 2001; 61: 8188-93.
    • (2001) Cancer Res , vol.61 , pp. 8188-8193
    • Bergmann, M.1    Romirer, I.2    Sachet, M.3
  • 30
    • 0034671477 scopus 로고    scopus 로고
    • Antitumor properties of influenza virus vectors
    • Zheng H, Palese P, Garcia-Sastre A. Antitumor properties of influenza virus vectors. Cancer Res 2000; 60: 6972-6.
    • (2000) Cancer Res , vol.60 , pp. 6972-6976
    • Zheng, H.1    Palese, P.2    Garcia-Sastre, A.3
  • 31
    • 0035576889 scopus 로고    scopus 로고
    • RNA replicons derived from poliovirus are directly oncolytic for human tumor cells of diverse origins
    • Ansardi DC, Porter DC, Jackson CA, Gillespie GY, Morrow CD. RNA replicons derived from poliovirus are directly oncolytic for human tumor cells of diverse origins. Cancer Res 2001; 61: 8470-9.
    • (2001) Cancer Res , vol.61 , pp. 8470-8479
    • Ansardi, D.C.1    Porter, D.C.2    Jackson, C.A.3    Gillespie, G.Y.4    Morrow, C.D.5
  • 32
    • 0034026546 scopus 로고    scopus 로고
    • Immunomodulation of cancer: Potential use of selectively replicating agents
    • Agha-Mohammadi S, Lotze MT. Immunomodulation of cancer: potential use of selectively replicating agents. J Clin Invest 2000; 105: 1173-6.
    • (2000) J Clin Invest , vol.105 , pp. 1173-1176
    • Agha-Mohammadi, S.1    Lotze, M.T.2
  • 33
    • 0034924079 scopus 로고    scopus 로고
    • Positron emission tomography imaging for herpes virus infection: Implications for oncolytic viral treatments of cancer
    • Bennett JJ, Tjuvajev J, Johnson P, et al. Positron emission tomography imaging for herpes virus infection: implications for oncolytic viral treatments of cancer. Nat Med 2001; 7: 859-63.
    • (2001) Nat Med , vol.7 , pp. 859-863
    • Bennett, J.J.1    Tjuvajev, J.2    Johnson, P.3
  • 34
    • 0026772206 scopus 로고
    • In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors
    • Culver KW, Ram Z, Wallbridge S, Ishii H, Oldfield EH, Blaese RM. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 1992; 256: 1550-2.
    • (1992) Science , vol.256 , pp. 1550-1552
    • Culver, K.W.1    Ram, Z.2    Wallbridge, S.3    Ishii, H.4    Oldfield, E.H.5    Blaese, R.M.6
  • 35
    • 0022485359 scopus 로고
    • Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
    • Moolten FL. Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. Cancer Res 1986; 46: 5276-81.
    • (1986) Cancer Res , vol.46 , pp. 5276-5281
    • Moolten, F.L.1
  • 36
    • 0031985463 scopus 로고    scopus 로고
    • Suicide genes against brain tumors
    • Paillard F. Suicide genes against brain tumors. Hum Gene Ther 1998; 9: 3-4.
    • (1998) Hum Gene Ther , vol.9 , pp. 3-4
    • Paillard, F.1
  • 37
    • 0024318150 scopus 로고
    • Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate
    • Coen DM, Kosz-Vnenchak M, Jacobson JG, et al. Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate. Proc Natl Acad Sci USA 1989; 86: 4736-40.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 4736-4740
    • Coen, D.M.1    Kosz-Vnenchak, M.2    Jacobson, J.G.3
  • 38
    • 0027419624 scopus 로고
    • Reduction and elimination of encephalitis in an experimental glioma therapy model with attenuated herpes simplex mutants that retain susceptibility to acyclovir
    • Markert JM, Malick A, Coen DM, Martuza RL. Reduction and elimination of encephalitis in an experimental glioma therapy model with attenuated herpes simplex mutants that retain susceptibility to acyclovir. Neurosurgery 1993; 32: 597-603.
    • (1993) Neurosurgery , vol.32 , pp. 597-603
    • Markert, J.M.1    Malick, A.2    Coen, D.M.3    Martuza, R.L.4
  • 39
    • 0036494383 scopus 로고    scopus 로고
    • Treatment of ovarian cancer with a tropism modified oncolytic adenovirus
    • Bauerschmitz GJ, Lam JT, Kanerva A, et al. Treatment of ovarian cancer with a tropism modified oncolytic adenovirus. Cancer Res 2002; 62: 1266-70.
    • (2002) Cancer Res , vol.62 , pp. 1266-1270
    • Bauerschmitz, G.J.1    Lam, J.T.2    Kanerva, A.3
  • 40
    • 0035114089 scopus 로고    scopus 로고
    • Efficient oncolysis by a replicating adenovirus (ad) in vivo is critically dependent on tumor expression of primary ad receptors
    • Douglas JT, Kim M, Sumerel LA, Carey DE, Curiel DT, Efficient oncolysis by a replicating adenovirus (ad) in vivo is critically dependent on tumor expression of primary ad receptors. Cancer Res 2001; 61: 813-7.
    • (2001) Cancer Res , vol.61 , pp. 813-817
    • Douglas, J.T.1    Kim, M.2    Sumerel, L.A.3    Carey, D.E.4    Curiel, D.T.5
  • 41
    • 0035138689 scopus 로고    scopus 로고
    • A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency
    • Suzuki K, Fueyo J, Krasnykh V, Reynolds PN, Curiel DT, Alemany R. A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency. Clin Cancer Res 2001; 7: 120-6.
    • (2001) Clin Cancer Res , vol.7 , pp. 120-126
    • Suzuki, K.1    Fueyo, J.2    Krasnykh, V.3    Reynolds, P.N.4    Curiel, D.T.5    Alemany, R.6
  • 42
    • 0035418580 scopus 로고    scopus 로고
    • Targeting oncolytic adenoviral agents to the epidermal growth factor pathway with a secretory fusion molecule
    • Hemminki A, Dmitriev I, Liu B, Desmond RA, Alemany R, Curiel DT. Targeting oncolytic adenoviral agents to the epidermal growth factor pathway with a secretory fusion molecule. Cancer Res 2001; 61: 6377-81.
    • (2001) Cancer Res , vol.61 , pp. 6377-6381
    • Hemminki, A.1    Dmitriev, I.2    Liu, B.3    Desmond, R.A.4    Alemany, R.5    Curiel, D.T.6
  • 43
    • 0344188096 scopus 로고    scopus 로고
    • An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
    • Bischoff JR, Kirn DH, Williams A, et al. An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science 1996; 274: 373-6.
    • (1996) Science , vol.274 , pp. 373-376
    • Bischoff, J.R.1    Kirn, D.H.2    Williams, A.3
  • 44
    • 0034759057 scopus 로고    scopus 로고
    • Re-engineering adenovirus regulatory pathways to enhance oncolytic specificity and efficacy
    • Ramachandra M, Rahman A, Zou A, et al. Re-engineering adenovirus regulatory pathways to enhance oncolytic specificity and efficacy. Nat Biotechnol 2001; 19: 1035-41.
    • (2001) Nat Biotechnol , vol.19 , pp. 1035-1041
    • Ramachandra, M.1    Rahman, A.2    Zou, A.3
  • 45
    • 0035120593 scopus 로고    scopus 로고
    • Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathway
    • Brunori M, Malerba M, Kashiwazaki H, Iggo R. Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathway J Virol 2001; 75: 2857-65.
    • (2001) J Virol , vol.75 , pp. 2857-2865
    • Brunori, M.1    Malerba, M.2    Kashiwazaki, H.3    Iggo, R.4
  • 46
    • 0035881263 scopus 로고    scopus 로고
    • A conditional replication-competent adenoviral vector, Ad-OC-E1a, to co-target prostate cancer and bone stroma in an experimental model of androgen-independent prostate cancer bone metastasis
    • Matsubara S, Wada Y, Gardner TA, et al. A conditional replication-competent adenoviral vector, Ad-OC-E1a, to co-target prostate cancer and bone stroma in an experimental model of androgen-independent prostate cancer bone metastasis. Cancer Res 2001; 61: 6012-9.
    • (2001) Cancer Res , vol.61 , pp. 6012-6019
    • Matsubara, S.1    Wada, Y.2    Gardner, T.A.3
  • 47
    • 0035503241 scopus 로고    scopus 로고
    • A midkine promoter-based conditionally replicative adenovirus for treatment of pediatric solid tumors and bone marrow tumor purging
    • Adachi Y, Reynolds PN, Yamamoto M, et al. A midkine promoter-based conditionally replicative adenovirus for treatment of pediatric solid tumors and bone marrow tumor purging. Cancer Res 2001; 61: 7882-8.
    • (2001) Cancer Res , vol.61 , pp. 7882-7888
    • Adachi, Y.1    Reynolds, P.N.2    Yamamoto, M.3
  • 48
    • 0035879042 scopus 로고    scopus 로고
    • CV706, a prostate cancer-specific adenovirus variant, in combination with radiotherapy produces synergistic antitumor efficacy without increasing toxicity
    • Chen Y, DeWeese T, Dilley J, et al. CV706, a prostate cancer-specific adenovirus variant, in combination with radiotherapy produces synergistic antitumor efficacy without increasing toxicity. Cancer Res 2001; 61: 5453-60.
    • (2001) Cancer Res , vol.61 , pp. 5453-5460
    • Chen, Y.1    DeWeese, T.2    Dilley, J.3
  • 49
    • 0035887153 scopus 로고    scopus 로고
    • A phase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy
    • DeWeese TL, van der Poel H, Li S, et al. A phase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy. Cancer Res 2001; 61: 7464-72.
    • (2001) Cancer Res , vol.61 , pp. 7464-7472
    • DeWeese, T.L.1    Van Der Poel, H.2    Li, S.3
  • 50
    • 0035863499 scopus 로고    scopus 로고
    • Antitumor synergy of CV787, a prostate cancer-specific adenovirus, and paclitaxel and docetaxel
    • Yu DC, Chen Y, Dilley J, et al. Antitumor synergy of CV787, a prostate cancer-specific adenovirus, and paclitaxel and docetaxel. Cancer Res 2001; 61: 517-25.
    • (2001) Cancer Res , vol.61 , pp. 517-525
    • Yu, D.C.1    Chen, Y.2    Dilley, J.3
  • 51
    • 0028937785 scopus 로고
    • Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
    • Yang Y, Li Q, Ertl HC, Wilson JM. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J Virol 1995; 69: 2004-15.
    • (1995) J Virol , vol.69 , pp. 2004-2015
    • Yang, Y.1    Li, Q.2    Ertl, H.C.3    Wilson, J.M.4
  • 52
    • 14344276590 scopus 로고    scopus 로고
    • An improved helper-dependent adenoviral vector allows persistent gene expression after intramuscular delivery and overcomes preexisting immunity to adenovirus
    • Maione D, Della Rocca C, Giannetti P, et al. An improved helper-dependent adenoviral vector allows persistent gene expression after intramuscular delivery and overcomes preexisting immunity to adenovirus. Proc Natl Acad Sci USA 2001; 98: 5986-91.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5986-5991
    • Maione, D.1    Della Rocca, C.2    Giannetti, P.3
  • 53
    • 0034926344 scopus 로고    scopus 로고
    • Preexisting antiadenoviral immunity is not a barrier to efficient and stable transduction of the brain, mediated by novel high-capacity adenovirus vectors
    • Thomas CE, Schiedner G, Kochanek S, Castro MG, Lowenstein PR. Preexisting antiadenoviral immunity is not a barrier to efficient and stable transduction of the brain, mediated by novel high-capacity adenovirus vectors. Hum Gene Ther 2001; 12: 839-46.
    • (2001) Hum Gene Ther , vol.12 , pp. 839-846
    • Thomas, C.E.1    Schiedner, G.2    Kochanek, S.3    Castro, M.G.4    Lowenstein, P.R.5
  • 54
    • 0033900009 scopus 로고    scopus 로고
    • Bystander effect in herpes simplex virus-thymidine kinase/ganciclovir cancer gene therapy: Role of gap-junctional intercellular communication
    • Mesnil M, Yamasaki H. Bystander effect in herpes simplex virus-thymidine kinase/ganciclovir cancer gene therapy: role of gap-junctional intercellular communication. Cancer Res 2000; 60: 3989-99.
    • (2000) Cancer Res , vol.60 , pp. 3989-3999
    • Mesnil, M.1    Yamasaki, H.2
  • 55
    • 0027483695 scopus 로고
    • The 'bystander effect': Tumor regression when a fraction of the tumor mass is genetically modified
    • Freeman SM, Abboud CN, Whartenby KA, et al. The 'bystander effect': tumor regression when a fraction of the tumor mass is genetically modified. Cancer Res 1993; 53: 5274-83.
    • (1993) Cancer Res , vol.53 , pp. 5274-5283
    • Freeman, S.M.1    Abboud, C.N.2    Whartenby, K.A.3
  • 56
    • 0033217787 scopus 로고    scopus 로고
    • Suicidal gene therapy for pleural metastasis of lung cancer by liposome-mediated transfer of herpes simplex virus thymidine kinase gene
    • Nagamachi Y, Tani M, Shimizu K, Yoshida T, Yokota J. Suicidal gene therapy for pleural metastasis of lung cancer by liposome-mediated transfer of herpes simplex virus thymidine kinase gene. Cancer Gene Ther 1999; 6: 546-53.
    • (1999) Cancer Gene Ther , vol.6 , pp. 546-553
    • Nagamachi, Y.1    Tani, M.2    Shimizu, K.3    Yoshida, T.4    Yokota, J.5
  • 57
    • 0035893397 scopus 로고    scopus 로고
    • Treatment of malignant gliomas with a replicating adenoviral vector expressing herpes simplex virus-thymidine kinase
    • Nanda D, Vogels R, Havenga M, Avezaat CJ, Bout A, Smitt PS. Treatment of malignant gliomas with a replicating adenoviral vector expressing herpes simplex virus-thymidine kinase. Cancer Res 2001; 61: 8743-50.
    • (2001) Cancer Res , vol.61 , pp. 8743-8750
    • Nanda, D.1    Vogels, R.2    Havenga, M.3    Avezaat, C.J.4    Bout, A.5    Smitt, P.S.6
  • 58
    • 0033556003 scopus 로고    scopus 로고
    • Therapy of colon cancer with oncolytic adenovirus is enhanced by the addition of herpes simplex virus-thymidine kinase
    • Wildner O, Blaese RM, Morris JC. Therapy of colon cancer with oncolytic adenovirus is enhanced by the addition of herpes simplex virus-thymidine kinase. Cancer Res 1999; 59: 410-3.
    • (1999) Cancer Res , vol.59 , pp. 410-413
    • Wildner, O.1    Blaese, R.M.2    Morris, J.C.3
  • 59
    • 0033895515 scopus 로고    scopus 로고
    • The role of the E1B 55 kDa gene product in oncolytic adenoviral vectors expressing herpes simplex virus-tk: Assessment of antitumor efficacy and toxicity
    • Wildner O, Morris JC. The role of the E1B 55 kDa gene product in oncolytic adenoviral vectors expressing herpes simplex virus-tk: assessment of antitumor efficacy and toxicity. Cancer Res 2000; 60: 4167-74.
    • (2000) Cancer Res , vol.60 , pp. 4167-4174
    • Wildner, O.1    Morris, J.C.2
  • 60
    • 16944364591 scopus 로고    scopus 로고
    • Safety of intrapleurally administered recombinant adenovirus carrying herpes simplex thymidine kinase DNA followed by ganciclovir therapy in nonhuman primates
    • Kucharczuk JC, Raper S, Elshami AA, et al. Safety of intrapleurally administered recombinant adenovirus carrying herpes simplex thymidine kinase DNA followed by ganciclovir therapy in nonhuman primates. Hum Gene Ther 1996; 7: 2225-33.
    • (1996) Hum Gene Ther , vol.7 , pp. 2225-2233
    • Kucharczuk, J.C.1    Raper, S.2    Elshami, A.A.3
  • 61
    • 17344365922 scopus 로고    scopus 로고
    • Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: Results of a phase I clinical trial in malignant mesothelioma
    • Sterman DH, Treat J, Litzky LA, et al. Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma. Hum Gene Ther 1998; 9: 1083-92.
    • (1998) Hum Gene Ther , vol.9 , pp. 1083-1092
    • Sterman, D.H.1    Treat, J.2    Litzky, L.A.3
  • 62
    • 0032922211 scopus 로고    scopus 로고
    • Adenoviral vectors capable of replication improve the efficacy of HSVtk/GCV suicide gene therapy of cancer
    • Wildner O, Morris JC, Vahanian NN, Ford H Jr, Ramsey WJ, Blaese RM. Adenoviral vectors capable of replication improve the efficacy of HSVtk/GCV suicide gene therapy of cancer. Gene Ther 1999; 6: 57-62.
    • (1999) Gene Ther , vol.6 , pp. 57-62
    • Wildner, O.1    Morris, J.C.2    Vahanian, N.N.3    Ford Jr., H.4    Ramsey, W.J.5    Blaese, R.M.6
  • 63
    • 0034956825 scopus 로고    scopus 로고
    • Inclusion of the herpes simplex thymidine kinase gene in a replicating adenovirus does not augment antitumor efficacy
    • Lambright ES, Amin K, Wiewrodt R, et al. Inclusion of the herpes simplex thymidine kinase gene in a replicating adenovirus does not augment antitumor efficacy. Gene Ther 2001; 8: 946-53.
    • (2001) Gene Ther , vol.8 , pp. 946-953
    • Lambright, E.S.1    Amin, K.2    Wiewrodt, R.3
  • 64
    • 0030916131 scopus 로고    scopus 로고
    • Protection of herpes simplex virus thymidine kinase-transduced cells from ganciclovir-mediated cytotoxicity by bystander cells: The Good Samaritan effect
    • Wygoda MR, Wilson MR, Davis MA, Trosko JE, Rehemtulla A, Lawrence TS. Protection of herpes simplex virus thymidine kinase-transduced cells from ganciclovir-mediated cytotoxicity by bystander cells: the Good Samaritan effect. Cancer Res 1997; 57: 1699-703.
    • (1997) Cancer Res , vol.57 , pp. 1699-1703
    • Wygoda, M.R.1    Wilson, M.R.2    Davis, M.A.3    Trosko, J.E.4    Rehemtulla, A.5    Lawrence, T.S.6
  • 65
    • 0028202066 scopus 로고
    • Gene therapy for brain tumors: Regression of experimental gliomas by adenovirus-mediated gene transfer in vivo
    • Chen SH, Shine HD, Goodman JC, Grossman RG, Woo SL. Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo. Proc Natl Acad Sci USA 1994; 91: 3054-7.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3054-3057
    • Chen, S.H.1    Shine, H.D.2    Goodman, J.C.3    Grossman, R.G.4    Woo, S.L.5
  • 66
    • 0032503659 scopus 로고    scopus 로고
    • A novel three-pronged approach to kill cancer cells selectively: Concomitant viral, double suicide gene, and radiotherapy
    • Freytag SO, Rogulski KR, Paielli DL, Gilbert JD, Kim JH. A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy. Hum Gene Ther 1998; 9: 1323-33.
    • (1998) Hum Gene Ther , vol.9 , pp. 1323-1333
    • Freytag, S.O.1    Rogulski, K.R.2    Paielli, D.L.3    Gilbert, J.D.4    Kim, J.H.5
  • 67
    • 0034161976 scopus 로고    scopus 로고
    • In vivo antitumor activity of ONYX-015 is influenced by p53 status and is augmented by radiotherapy
    • Rogulski KR, Freytag SO, Zhang K, et al. In vivo antitumor activity of ONYX-015 is influenced by p53 status and is augmented by radiotherapy. Cancer Res 2000; 60: 1193-6.
    • (2000) Cancer Res , vol.60 , pp. 1193-1196
    • Rogulski, K.R.1    Freytag, S.O.2    Zhang, K.3
  • 68
    • 0033984339 scopus 로고    scopus 로고
    • Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization
    • Rogulski KR, Wing MS, Paielli DL, Gilbert JD, Kim JH, Freytag SO. Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization. Hum Gene Ther 2000; 11: 67-76.
    • (2000) Hum Gene Ther , vol.11 , pp. 67-76
    • Rogulski, K.R.1    Wing, M.S.2    Paielli, D.L.3    Gilbert, J.D.4    Kim, J.H.5    Freytag, S.O.6
  • 69
    • 0029154946 scopus 로고
    • The role of immunosuppression in the efficacy of cancer gene therapy using adenovirus transfer of the herpes simplex thymidine kinase gene
    • Elshami AA, Kucharczuk JC, Sterman DH, et al. The role of immunosuppression in the efficacy of cancer gene therapy using adenovirus transfer of the herpes simplex thymidine kinase gene. Ann Surg 1995; 222: 298-310.
    • (1995) Ann Surg , vol.222 , pp. 298-310
    • Elshami, A.A.1    Kucharczuk, J.C.2    Sterman, D.H.3
  • 70
    • 0032549688 scopus 로고    scopus 로고
    • Intercellular communication mediates the bystander effect during herpes simplex thymidine kinase/ganciclovir-based gene therapy of human gastrointestinal tumor cells
    • Yang L, Chiang Y, Lenz HJ, et al. Intercellular communication mediates the bystander effect during herpes simplex thymidine kinase/ganciclovir-based gene therapy of human gastrointestinal tumor cells. Hum Gene Ther 1998; 9: 719-28.
    • (1998) Hum Gene Ther , vol.9 , pp. 719-728
    • Yang, L.1    Chiang, Y.2    Lenz, H.J.3
  • 71
    • 0027787053 scopus 로고
    • In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy
    • Bi WL, Parysek LM, Warnick R, Stambrook PJ. In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy. Hum Gene Ther 1993; 4: 725-31.
    • (1993) Hum Gene Ther , vol.4 , pp. 725-731
    • Bi, W.L.1    Parysek, L.M.2    Warnick, R.3    Stambrook, P.J.4
  • 72
    • 0031179187 scopus 로고    scopus 로고
    • An HSVtk-mediated local and distant antitumor bystander effect in tumors of head and neck origin in athymic mice
    • Bi W, Kim YG, Feliciano ES, et al. An HSVtk-mediated local and distant antitumor bystander effect in tumors of head and neck origin in athymic mice. Cancer Gene Ther 1997; 4: 246-52.
    • (1997) Cancer Gene Ther , vol.4 , pp. 246-252
    • Bi, W.1    Kim, Y.G.2    Feliciano, E.S.3
  • 73
    • 0028789833 scopus 로고
    • Development and application of herpes simplex virus vectors for human gene therapy
    • Glorioso JC, DeLuca NA, Fink DJ. Development and application of herpes simplex virus vectors for human gene therapy. Annu Rev Microbiol 1995; 49: 675-710.
    • (1995) Annu Rev Microbiol , vol.49 , pp. 675-710
    • Glorioso, J.C.1    DeLuca, N.A.2    Fink, D.J.3
  • 74
    • 0032720040 scopus 로고    scopus 로고
    • Molecular genetic analysis of herpesviruses and their potential use as vectors for gene therapy applications
    • Cotter MA, Robertson ES. Molecular genetic analysis of herpesviruses and their potential use as vectors for gene therapy applications. Curr Opin Mol Ther 1999; 1: 633-44.
    • (1999) Curr Opin Mol Ther , vol.1 , pp. 633-644
    • Cotter, M.A.1    Robertson, E.S.2
  • 75
    • 0028558776 scopus 로고
    • Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus, and retrovirus vectors
    • Boviatsis EJ, Chase M, Wei MX, et al. Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus, and retrovirus vectors. Hum Gene Ther 1994; 5: 183-91.
    • (1994) Hum Gene Ther , vol.5 , pp. 183-191
    • Boviatsis, E.J.1    Chase, M.2    Wei, M.X.3
  • 77
    • 0032829989 scopus 로고    scopus 로고
    • Engineering herpes simplex virus vectors for CNS applications
    • Wolfe D, Goins WF, Yamada M, et al. Engineering herpes simplex virus vectors for CNS applications. Exp Neurol 1999; 159: 34-46.
    • (1999) Exp Neurol , vol.159 , pp. 34-46
    • Wolfe, D.1    Goins, W.F.2    Yamada, M.3
  • 78
    • 0030919279 scopus 로고    scopus 로고
    • Herpes simplex virus vectors for gene transfer to the nervous system
    • Goins WF, Krisky D, Marconi P, et al. Herpes simplex virus vectors for gene transfer to the nervous system. J Neurovirol 1997; 3(Suppl 1): S80-8.
    • (1997) J Neurovirol , vol.3 , Issue.1 SUPPL.
    • Goins, W.F.1    Krisky, D.2    Marconi, P.3
  • 79
    • 0029859684 scopus 로고    scopus 로고
    • The function of herpes simplex virus genes: A primer for genetic engineering of novel vectors
    • Roizman B. The function of herpes simplex virus genes: a primer for genetic engineering of novel vectors. Proc Natl Acad Sci USA 1996; 93: 11307-12.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11307-11312
    • Roizman, B.1
  • 80
    • 0025225452 scopus 로고
    • An efficient deletion mutant packaging system for defective herpes simplex virus vectors: Potential applications to human gene therapy and neuronal physiology
    • Geller AI, Keyomarsi K, Bryan J, Pardee AB. An efficient deletion mutant packaging system for defective herpes simplex virus vectors: potential applications to human gene therapy and neuronal physiology. Proc Natl Acad Sci USA 1990; 87: 8950-4.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8950-8954
    • Geller, A.I.1    Keyomarsi, K.2    Bryan, J.3    Pardee, A.B.4
  • 81
    • 0029973972 scopus 로고    scopus 로고
    • Replication-defective herpes simplex virus vectors for gene transfer in vivo
    • Marconi P, Krisky D, Oligino T, et al. Replication-defective herpes simplex virus vectors for gene transfer in vivo. Proc Natl Acad Sci USA 1996; 93: 11319-20.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11319-11320
    • Marconi, P.1    Krisky, D.2    Oligino, T.3
  • 82
    • 0029838241 scopus 로고    scopus 로고
    • A novel 'piggy-back' packaging system for herpes simplex virus amplicon vectors
    • Pechan PA, Fotaki M, Thompson RL, et al. A novel 'piggy-back' packaging system for herpes simplex virus amplicon vectors. Hum Gene Ther 1996; 7: 2003-13.
    • (1996) Hum Gene Ther , vol.7 , pp. 2003-2013
    • Pechan, P.A.1    Fotaki, M.2    Thompson, R.L.3
  • 83
    • 0033589748 scopus 로고    scopus 로고
    • Disabled infectious single-cycle herpes simplex virus as an oncolytic vector for immunotherapy of colorectal cancer
    • Todryk S, McLean C, Ali S, et al. Disabled infectious single-cycle herpes simplex virus as an oncolytic vector for immunotherapy of colorectal cancer. Hum Gene Ther 1999; 10: 2757-68.
    • (1999) Hum Gene Ther , vol.10 , pp. 2757-2768
    • Todryk, S.1    McLean, C.2    Ali, S.3
  • 84
    • 0017840246 scopus 로고
    • Inhibition of herpes simplex virus type 1 replication in temperature-sensitive cell cycle mutants
    • Yanagi K, Talavera A, Nishimoto T, Rush MG. Inhibition of herpes simplex virus type 1 replication in temperature-sensitive cell cycle mutants. J Virol 1978; 25: 42-50.
    • (1978) J Virol , vol.25 , pp. 42-50
    • Yanagi, K.1    Talavera, A.2    Nishimoto, T.3    Rush, M.G.4
  • 85
    • 0035878847 scopus 로고    scopus 로고
    • Comparative analyses of transgene delivery and expression in tumors inoculated with a replication-conditional or -defective viral vector
    • Ichikawa T, Chiocca EA. Comparative analyses of transgene delivery and expression in tumors inoculated with a replication-conditional or -defective viral vector. Cancer Res 2001; 61: 5336-9.
    • (2001) Cancer Res , vol.61 , pp. 5336-5339
    • Ichikawa, T.1    Chiocca, E.A.2
  • 86
    • 0026785257 scopus 로고
    • Expanded spectrum of viral therapy in the treatment of nervous system tumors
    • Markert JM, Coen DM, Malick A, Mineta T, Martuza RL. Expanded spectrum of viral therapy in the treatment of nervous system tumors. J Neurosurg 1992; 77: 590-4.
    • (1992) J Neurosurg , vol.77 , pp. 590-594
    • Markert, J.M.1    Coen, D.M.2    Malick, A.3    Mineta, T.4    Martuza, R.L.5
  • 87
    • 12944315014 scopus 로고    scopus 로고
    • Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: Results of a phase I trial
    • Markert JM, Medlock MD, Rabkin SD, et al. Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial. Gene Ther 2000; 7: 867-74.
    • (2000) Gene Ther , vol.7 , pp. 867-874
    • Markert, J.M.1    Medlock, M.D.2    Rabkin, S.D.3
  • 88
    • 0025864440 scopus 로고
    • Experimental therapy of human glioma by means of a genetically engineered virus mutant
    • Martuza RL, Malick A, Markert JM, Ruffner KL, Coen DM. Experimental therapy of human glioma by means of a genetically engineered virus mutant. Science 1991; 252: 854-6.
    • (1991) Science , vol.252 , pp. 854-856
    • Martuza, R.L.1    Malick, A.2    Markert, J.M.3    Ruffner, K.L.4    Coen, D.M.5
  • 90
    • 0028108669 scopus 로고
    • Treatment of malignant gliomas using ganciclovir-hypersensitive, ribonucleotide reductase-deficient herpes simplex viral mutant
    • Mineta T, Rabkin SD, Martuza RL. Treatment of malignant gliomas using ganciclovir-hypersensitive, ribonucleotide reductase-deficient herpes simplex viral mutant. Cancer Res 1994; 54: 3963-6.
    • (1994) Cancer Res , vol.54 , pp. 3963-3966
    • Mineta, T.1    Rabkin, S.D.2    Martuza, R.L.3
  • 91
    • 0029023868 scopus 로고
    • Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas
    • Mineta T, Rabkin SD, Yazaki T, Hunter WD, Martuza RL. Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas. Nat Med 1995; 1: 938-43.
    • (1995) Nat Med , vol.1 , pp. 938-943
    • Mineta, T.1    Rabkin, S.D.2    Yazaki, T.3    Hunter, W.D.4    Martuza, R.L.5
  • 92
    • 0033140039 scopus 로고    scopus 로고
    • Replication-competent herpes simplex virus vector G207 and cisplatin combination therapy for head and neck squamous cell carcinoma
    • Chahlavi A, Todo T, Martuza RL, Rabkin SD. Replication-competent herpes simplex virus vector G207 and cisplatin combination therapy for head and neck squamous cell carcinoma. Neoplasia 1999; 1: 162-9.
    • (1999) Neoplasia , vol.1 , pp. 162-169
    • Chahlavi, A.1    Todo, T.2    Martuza, R.L.3    Rabkin, S.D.4
  • 93
    • 0033875563 scopus 로고    scopus 로고
    • Oncolytic herpes simplex virus-1 lacking ICP34.5 induces p53-independent death and is efficacious against chemotherapy-resistant ovarian cancer
    • Coukos G, Makrigiannakis A, Kang EH, Rubin SC, Albelda SM, Molnar-Kimber KL. Oncolytic herpes simplex virus-1 lacking ICP34.5 induces p53-independent death and is efficacious against chemotherapy-resistant ovarian cancer. Clin Cancer Res 2000; 6: 3342-53.
    • (2000) Clin Cancer Res , vol.6 , pp. 3342-3353
    • Coukos, G.1    Makrigiannakis, A.2    Kang, E.H.3    Rubin, S.C.4    Albelda, S.M.5    Molnar-Kimber, K.L.6
  • 94
    • 0034032455 scopus 로고    scopus 로고
    • Multi-attenuated herpes simplex virus-1 mutant G207 exerts cytotoxicity against epithelial ovarian cancer but not normal mesothelium and is suitable for intraperitoneal oncolytic therapy
    • Coukos G, Makrigiannakis A, Montas S, et al. Multi-attenuated herpes simplex virus-1 mutant G207 exerts cytotoxicity against epithelial ovarian cancer but not normal mesothelium and is suitable for intraperitoneal oncolytic therapy. Cancer Gene Ther 2000; 7: 275-83.
    • (2000) Cancer Gene Ther , vol.7 , pp. 275-283
    • Coukos, G.1    Makrigiannakis, A.2    Montas, S.3
  • 95
    • 0030914772 scopus 로고    scopus 로고
    • Treatment of experimental subcutaneous human melanoma with a replication-restricted herpes simplex virus mutant
    • Randazzo BP, Bhat MG, Kesari S, Fraser NW, Brown SM. Treatment of experimental subcutaneous human melanoma with a replication-restricted herpes simplex virus mutant. J Invest Dermatol 1997; 108: 933-7.
    • (1997) J Invest Dermatol , vol.108 , pp. 933-937
    • Randazzo, B.P.1    Bhat, M.G.2    Kesari, S.3    Fraser, N.W.4    Brown, S.M.5
  • 96
    • 0034950470 scopus 로고    scopus 로고
    • Effective treatment of head and neck squamous cell carcinoma by an oncolytic herpes simplex virus
    • Wong RJ, Kim SH, Joe JK, Shah JP, Johnson PA, Fong Y. Effective treatment of head and neck squamous cell carcinoma by an oncolytic herpes simplex virus. J Am Coll Surg 2001; 193: 12-21.
    • (2001) J Am Coll Surg , vol.193 , pp. 12-21
    • Wong, R.J.1    Kim, S.H.2    Joe, J.K.3    Shah, J.P.4    Johnson, P.A.5    Fong, Y.6
  • 97
    • 0032471162 scopus 로고    scopus 로고
    • Cancer gene therapy using a replication-competent herpes simplex virus type 1 vector
    • Yoon SS, Carroll NM, Chiocca EA, Tanabe KK. Cancer gene therapy using a replication-competent herpes simplex virus type 1 vector. Ann Surg 1998; 228: 366-74.
    • (1998) Ann Surg , vol.228 , pp. 366-374
    • Yoon, S.S.1    Carroll, N.M.2    Chiocca, E.A.3    Tanabe, K.K.4
  • 98
    • 0031610546 scopus 로고    scopus 로고
    • A study of the pharmacokinetics, antiviral activity, and tolerability of oral ganciclovir for CMV prophylaxis in marrow transplantation
    • Boeckh M, Zaia JA, Jung D, Skettino S, Chauncey TR, Bowden RA. A study of the pharmacokinetics, antiviral activity, and tolerability of oral ganciclovir for CMV prophylaxis in marrow transplantation. Biol Blood Marrow Transplant 1998; 4: 13-9.
    • (1998) Biol Blood Marrow Transplant , vol.4 , pp. 13-19
    • Boeckh, M.1    Zaia, J.A.2    Jung, D.3    Skettino, S.4    Chauncey, T.R.5    Bowden, R.A.6
  • 99
    • 0035985948 scopus 로고    scopus 로고
    • Neutrophil dysplasia characterised by a pseudo-Pelger-Huet anomaly occurring with the use of mycophenolate mofetil and ganciclovir following renal transplantation: A report of five cases
    • Kennedy GA, Kay TD, Johnson DW, et al. Neutrophil dysplasia characterised by a pseudo-Pelger-Huet anomaly occurring with the use of mycophenolate mofetil and ganciclovir following renal transplantation: a report of five cases. Pathology 2002; 34: 263-6.
    • (2002) Pathology , vol.34 , pp. 263-266
    • Kennedy, G.A.1    Kay, T.D.2    Johnson, D.W.3
  • 100
    • 0032809464 scopus 로고    scopus 로고
    • Ganciclovir-induced encephalopathy in a bone marrow transplant recipient
    • Sharathkumar A, Shaw P. Ganciclovir-induced encephalopathy in a bone marrow transplant recipient. Bone Marrow Transplant 1999; 24: 421-3.
    • (1999) Bone Marrow Transplant , vol.24 , pp. 421-423
    • Sharathkumar, A.1    Shaw, P.2
  • 101
    • 0034062033 scopus 로고    scopus 로고
    • Safety and efficacy of granulocyte colony-stimulating factor in kidney and liver transplant recipients
    • Turgeon N, Hovingh GK, Fishman JA, et al. Safety and efficacy of granulocyte colony-stimulating factor in kidney and liver transplant recipients. Transpl Infect Dis 2000; 2: 15-21.
    • (2000) Transpl Infect Dis , vol.2 , pp. 15-21
    • Turgeon, N.1    Hovingh, G.K.2    Fishman, J.A.3
  • 102
    • 0035300565 scopus 로고    scopus 로고
    • Herpes simplex virus-1 thymidine kinase mutants created by semi-random sequence mutagenesis improve prodrug-mediated tumor cell killing
    • Black ME, Kokoris MS, Sabo P. Herpes simplex virus-1 thymidine kinase mutants created by semi-random sequence mutagenesis improve prodrug-mediated tumor cell killing. Cancer Res 2001; 61: 3022-6.
    • (2001) Cancer Res , vol.61 , pp. 3022-3026
    • Black, M.E.1    Kokoris, M.S.2    Sabo, P.3
  • 103
    • 0031183754 scopus 로고    scopus 로고
    • Defective herpes simplex virus vectors expressing thymidine kinase for the treatment of malignant glioma
    • Miyatake S, Martuza RL, Rabkin SD. Defective herpes simplex virus vectors expressing thymidine kinase for the treatment of malignant glioma. Cancer Gene Ther 1997; 4: 222-8.
    • (1997) Cancer Gene Ther , vol.4 , pp. 222-228
    • Miyatake, S.1    Martuza, R.L.2    Rabkin, S.D.3
  • 104
    • 0033800317 scopus 로고    scopus 로고
    • HSV vector cytotoxicity is inversely correlated with effective TK/GCV suicide gene therapy of rat gliosarcoma
    • Moriuchi S, Krisky DM, Marconi PC, et al. HSV vector cytotoxicity is inversely correlated with effective TK/GCV suicide gene therapy of rat gliosarcoma. Gene Ther 2000; 7: 1483-90.
    • (2000) Gene Ther , vol.7 , pp. 1483-1490
    • Moriuchi, S.1    Krisky, D.M.2    Marconi, P.C.3
  • 105
    • 0035878715 scopus 로고    scopus 로고
    • Multimodality therapy with a replication-conditional herpes simplex virus 1 mutant that expresses yeast cytosine deaminase for intratumoral conversion of 5-fluorocytosine to 5-fluorouracil
    • Nakamura H, Mullen JT, Chandrasekhar S, Pawlik TM, Yoon SS, Tanabe KK. Multimodality therapy with a replication-conditional herpes simplex virus 1 mutant that expresses yeast cytosine deaminase for intratumoral conversion of 5-fluorocytosine to 5-fluorouracil. Cancer Res 2001; 61: 5447-52.
    • (2001) Cancer Res , vol.61 , pp. 5447-5452
    • Nakamura, H.1    Mullen, J.T.2    Chandrasekhar, S.3    Pawlik, T.M.4    Yoon, S.S.5    Tanabe, K.K.6
  • 106
    • 0031947191 scopus 로고    scopus 로고
    • An oncolytic viral mutant that delivers the CYP2B1 transgene and augments cyclophosphamide chemotherapy
    • Chase M, Chung RY, Chiocca EA. An oncolytic viral mutant that delivers the CYP2B1 transgene and augments cyclophosphamide chemotherapy. Nat Biotechnol 1998; 16: 444-8.
    • (1998) Nat Biotechnol , vol.16 , pp. 444-448
    • Chase, M.1    Chung, R.Y.2    Chiocca, E.A.3
  • 107
    • 0034169521 scopus 로고    scopus 로고
    • Neural precursor cells for delivery of replication-conditional HSV-1 vectors to intracerebral gliomas
    • Herrlinger U, Woiciechowski C, Sena-Esteves M, et al. Neural precursor cells for delivery of replication-conditional HSV-1 vectors to intracerebral gliomas. Mol Ther 2000; 1: 347-57.
    • (2000) Mol Ther , vol.1 , pp. 347-357
    • Herrlinger, U.1    Woiciechowski, C.2    Sena-Esteves, M.3
  • 108
    • 0035116213 scopus 로고    scopus 로고
    • Intraneoplastic polymer-based delivery of cyclophosphamide for intratumoral bioconversion by a replicating oncolytic viral vector
    • Ichikawa T, Petros WP, Ludeman SM, et al. Intraneoplastic polymer-based delivery of cyclophosphamide for intratumoral bioconversion by a replicating oncolytic viral vector. Cancer Res 2001; 61: 864-8.
    • (2001) Cancer Res , vol.61 , pp. 864-868
    • Ichikawa, T.1    Petros, W.P.2    Ludeman, S.M.3
  • 109
    • 0034212631 scopus 로고    scopus 로고
    • Oncolysis of diffuse hepatocellular carcinoma by intravascular administration of a replication-competent, genetically engineered herpesvirus
    • Pawlik TM, Nakamura H, Yoon SS, et al. Oncolysis of diffuse hepatocellular carcinoma by intravascular administration of a replication-competent, genetically engineered herpesvirus. Cancer Res 2000; 60: 2790-5.
    • (2000) Cancer Res , vol.60 , pp. 2790-2795
    • Pawlik, T.M.1    Nakamura, H.2    Yoon, S.S.3
  • 110
    • 0028016249 scopus 로고
    • Selective destruction of gliomas in immunocompetent rats by thymidine kinase-defective herpes simplex virus type 1
    • Jia WW, McDermott M, Goldie J, Cynader M, Tan J, Tufaro F. Selective destruction of gliomas in immunocompetent rats by thymidine kinase-defective herpes simplex virus type 1. J Natl Cancer Inst 1994; 86: 1209-15.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1209-1215
    • Jia, W.W.1    McDermott, M.2    Goldie, J.3    Cynader, M.4    Tan, J.5    Tufaro, F.6
  • 111
    • 0029810499 scopus 로고    scopus 로고
    • Toxicity studies in thymidine kinase-deficient herpes simplex virus therapy for malignant astrocytoma
    • Jia WW, Tan J, Redekop GJ, Goldie JH. Toxicity studies in thymidine kinase-deficient herpes simplex virus therapy for malignant astrocytoma. J Neurosurg 1996; 85: 662-6.
    • (1996) J Neurosurg , vol.85 , pp. 662-666
    • Jia, W.W.1    Tan, J.2    Redekop, G.J.3    Goldie, J.H.4
  • 112
    • 0028141887 scopus 로고
    • The herpes simplex virus type 1 strain 17+ gamma 34.5 deletion mutant 1716 is avirulent in SCID mice
    • Valyi-Nagy T, Fareed MU, O'Keefe JS, et al. The herpes simplex virus type 1 strain 17+ gamma 34.5 deletion mutant 1716 is avirulent in SCID mice. J Gen Virol 1994; 75: 2059-63.
    • (1994) J Gen Virol , vol.75 , pp. 2059-2063
    • Valyi-Nagy, T.1    Fareed, M.U.2    O'Keefe, J.S.3
  • 113
    • 0028321989 scopus 로고
    • A thymidine kinase-negative HSV-1 strain establishes a persistent infection in SCID mice that features uncontrolled peripheral replication but only marginal nervous system involvement
    • Valyi-Nagy T, Gesser RM, Raengsakulrach B, et al. A thymidine kinase-negative HSV-1 strain establishes a persistent infection in SCID mice that features uncontrolled peripheral replication but only marginal nervous system involvement. Virology 1994; 199: 484-90.
    • (1994) Virology , vol.199 , pp. 484-490
    • Valyi-Nagy, T.1    Gesser, R.M.2    Raengsakulrach, B.3
  • 114
    • 0023880185 scopus 로고
    • Herpes simplex virus type 1-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis: Isolation and characterization of an ICP6 lacZ insertion mutant
    • Goldstein DJ, Weller SK. Herpes simplex virus type 1-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis: isolation and characterization of an ICP6 lacZ insertion mutant. J Virol 1988; 62: 196-205.
    • (1988) J Virol , vol.62 , pp. 196-205
    • Goldstein, D.J.1    Weller, S.K.2
  • 115
    • 0034947844 scopus 로고    scopus 로고
    • Functional interaction between fluorodeoxyuridine-induced cellular alterations and replication of a ribonucleotide reductase-negative herpes simplex virus
    • Petrowsky H, Roberts GD, Kooby DA, et al. Functional interaction between fluorodeoxyuridine-induced cellular alterations and replication of a ribonucleotide reductase-negative herpes simplex virus. J Virol 2001; 75: 7050-8.
    • (2001) J Virol , vol.75 , pp. 7050-7058
    • Petrowsky, H.1    Roberts, G.D.2    Kooby, D.A.3
  • 116
    • 0035300468 scopus 로고    scopus 로고
    • Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo
    • Jacobs A, Tjuvajev JG, Dubrovin M, et al. Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo. Cancer Res 2001; 61: 2983-95.
    • (2001) Cancer Res , vol.61 , pp. 2983-2995
    • Jacobs, A.1    Tjuvajev, J.G.2    Dubrovin, M.3
  • 117
    • 0029818276 scopus 로고    scopus 로고
    • Long-term survival in a rodent model of disseminated brain tumors by combined intrathecal delivery of herpes vectors and ganciclovir treatment
    • Kramm CM, Rainov NG, Sena-Esteves M, et al. Long-term survival in a rodent model of disseminated brain tumors by combined intrathecal delivery of herpes vectors and ganciclovir treatment. Hum Gene Ther 1996; 7: 1989-94.
    • (1996) Hum Gene Ther , vol.7 , pp. 1989-1994
    • Kramm, C.M.1    Rainov, N.G.2    Sena-Esteves, M.3
  • 118
    • 0032756916 scopus 로고    scopus 로고
    • Intraperitoneal delivery of hrR3 and ganciclovir prolongs survival in mice with disseminated pancreatic cancer
    • Kasuya H, Nishiyama Y, Nomoto S, Hosono J, Takeda S, Nakao A. Intraperitoneal delivery of hrR3 and ganciclovir prolongs survival in mice with disseminated pancreatic cancer. J Surg Oncol 1999; 72: 136-41.
    • (1999) J Surg Oncol , vol.72 , pp. 136-141
    • Kasuya, H.1    Nishiyama, Y.2    Nomoto, S.3    Hosono, J.4    Takeda, S.5    Nakao, A.6
  • 119
    • 0032814773 scopus 로고    scopus 로고
    • Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses
    • Ikeda K, Ichikawa T, Wakimoto H, et al. Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses. Nat Med 1999; 5: 881-7.
    • (1999) Nat Med , vol.5 , pp. 881-887
    • Ikeda, K.1    Ichikawa, T.2    Wakimoto, H.3
  • 120
    • 0033997183 scopus 로고    scopus 로고
    • Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication-conditional herpes simplex virus mutant
    • Ikeda K, Wakimoto H, Ichikawa T, et al. Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication- conditional herpes simplex virus mutant. J Virol 2000; 74: 4765-75.
    • (2000) J Virol , vol.74 , pp. 4765-4775
    • Ikeda, K.1    Wakimoto, H.2    Ichikawa, T.3
  • 121
    • 0029906853 scopus 로고    scopus 로고
    • Therapy of a murine model of pediatric brain tumors using a herpes simplex virus type-1 ICP34.5 mutant and demonstration of viral replication within the CNS
    • Lasner TM, Kesari S, Brown SM, Lee VM, Fraser NW Trojanowski JQ. Therapy of a murine model of pediatric brain tumors using a herpes simplex virus type-1 ICP34.5 mutant and demonstration of viral replication within the CNS. J Neuropathol Exp Neurol 1996; 55: 1259-69.
    • (1996) J Neuropathol Exp Neurol , vol.55 , pp. 1259-1269
    • Lasner, T.M.1    Kesari, S.2    Brown, S.M.3    Lee, V.M.4    Fraser, N.W.5    Trojanowski, J.Q.6
  • 122
    • 0028892032 scopus 로고
    • Therapy of experimental human brain tumors using a neuroattenuated herpes simplex virus mutant
    • Kesari S, Randazzo BP, Valyi-Nagy T, et al. Therapy of experimental human brain tumors using a neuroattenuated herpes simplex virus mutant. Lab Invest 1995; 73: 636-48.
    • (1995) Lab Invest , vol.73 , pp. 636-648
    • Kesari, S.1    Randazzo, B.P.2    Valyi-Nagy, T.3
  • 123
    • 0031052384 scopus 로고    scopus 로고
    • Use of a 'replication-restricted' herpes virus to treat experimental human malignant mesothelioma
    • Kucharczuk JC, Randazzo B, Chang MY, et al. Use of a 'replication- restricted' herpes virus to treat experimental human malignant mesothelioma. Cancer Res 1997; 57: 466-71.
    • (1997) Cancer Res , vol.57 , pp. 466-471
    • Kucharczuk, J.C.1    Randazzo, B.2    Chang, M.Y.3
  • 124
    • 12944272092 scopus 로고    scopus 로고
    • Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma
    • Rampling R, Cruickshank G, Papanastassiou V, et al. Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma. Gene Ther 2000; 7: 859-66.
    • (2000) Gene Ther , vol.7 , pp. 859-866
    • Rampling, R.1    Cruickshank, G.2    Papanastassiou, V.3
  • 125
    • 85047699172 scopus 로고    scopus 로고
    • The potential for efficacy of the modified (ICP 34.5(-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: A proof of principle study
    • Papanastassiou V, Rampling R, Fraser M, et al. The potential for efficacy of the modified (ICP 34.5(-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of principle study. Gene Ther 2002; 9: 398-406.
    • (2002) Gene Ther , vol.9 , pp. 398-406
    • Papanastassiou, V.1    Rampling, R.2    Fraser, M.3
  • 126
    • 0029961357 scopus 로고    scopus 로고
    • The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors
    • Andreansky SS, He B, Gillespie GY, et al. The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors. Proc Natl Acad Sci USA 1996; 93: 11313-8.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11313-11318
    • Andreansky, S.S.1    He, B.2    Gillespie, G.Y.3
  • 127
    • 0028931228 scopus 로고
    • Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a seid mouse model of human malignant glioma
    • Chambers R, Gillespie GY, Soroceanu L, et al. Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a seid mouse model of human malignant glioma. Proc Natl Acad Sci USA 1995; 92: 1411-5.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1411-1415
    • Chambers, R.1    Gillespie, G.Y.2    Soroceanu, L.3
  • 128
    • 0030587476 scopus 로고    scopus 로고
    • Herpes simplex 1716 - An ICP 34.5 mutant - Is severely replication restricted in human skin xenografts in vivo
    • Randazzo BP, Kucharczuk JC, Litzky LA, et al. Herpes simplex 1716 - an ICP 34.5 mutant - is severely replication restricted in human skin xenografts in vivo. Virology 1996; 223: 392-5.
    • (1996) Virology , vol.223 , pp. 392-395
    • Randazzo, B.P.1    Kucharczuk, J.C.2    Litzky, L.A.3
  • 129
    • 0030897659 scopus 로고    scopus 로고
    • Evaluation of genetically engineered herpes simplex viruses as oncolytic agents for human malignant brain tumors
    • Andreansky S, Soroceanu L, Flotte ER, et al. Evaluation of genetically engineered herpes simplex viruses as oncolytic agents for human malignant brain tumors. Cancer Res 1997; 57: 1502-9.
    • (1997) Cancer Res , vol.57 , pp. 1502-1509
    • Andreansky, S.1    Soroceanu, L.2    Flotte, E.R.3
  • 130
    • 0035902471 scopus 로고    scopus 로고
    • Enhanced antitumor efficacy of a herpes simplex virus mutant isolated by genetic selection in cancer cells
    • Taneja S, MacGregor J, Markus S, Ha S, Mohr I. Enhanced antitumor efficacy of a herpes simplex virus mutant isolated by genetic selection in cancer cells. Proc Natl Acad Sci USA 2001; 98: 8804-8.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8804-8808
    • Taneja, S.1    MacGregor, J.2    Markus, S.3    Ha, S.4    Mohr, I.5
  • 131
    • 0031909185 scopus 로고    scopus 로고
    • Enhancement of replication of genetically engineered herpes simplex viruses by ionizing radiation: A new paradigm for destruction of therapeutically intractable tumors
    • Advani SJ, Sibley GS, Song PY, et al. Enhancement of replication of genetically engineered herpes simplex viruses by ionizing radiation: a new paradigm for destruction of therapeutically intractable tumors. Gene Ther 1998; 5: 160-5.
    • (1998) Gene Ther , vol.5 , pp. 160-165
    • Advani, S.J.1    Sibley, G.S.2    Song, P.Y.3
  • 132
    • 0033018852 scopus 로고    scopus 로고
    • Ionizing radiation improves survival in mice bearing intracranial high-grade gliomas injected with genetically modified herpes simplex virus
    • Bradley JD, Kataoka Y, Advani S, et al. Ionizing radiation improves survival in mice bearing intracranial high-grade gliomas injected with genetically modified herpes simplex virus. Clin Cancer Res 1999; 5: 1517-22.
    • (1999) Clin Cancer Res , vol.5 , pp. 1517-1522
    • Bradley, J.D.1    Kataoka, Y.2    Advani, S.3
  • 134
    • 0031963349 scopus 로고    scopus 로고
    • Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins
    • Andreansky S, He B, van Cott J, et al. Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins. Gene Ther 1998; 5: 121-30.
    • (1998) Gene Ther , vol.5 , pp. 121-130
    • Andreansky, S.1    He, B.2    Van Cott, J.3
  • 135
    • 0036212495 scopus 로고    scopus 로고
    • Regulation of herpes simplex virus gamma (1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5
    • Nakamura H, Kasuya H, Mullen JT, et al. Regulation of herpes simplex virus gamma (1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5. J Clin Invest 2002; 109: 871-82.
    • (2002) J Clin Invest , vol.109 , pp. 871-882
    • Nakamura, H.1    Kasuya, H.2    Mullen, J.T.3
  • 136
    • 17344362951 scopus 로고    scopus 로고
    • Therapeutic efficiency and safety of a second-generation replication-conditional HSV1 vector for brain tumor gene therapy
    • Kramm CM, Chase M, Herrlinger U, et al. Therapeutic efficiency and safety of a second-generation replication-conditional HSV1 vector for brain tumor gene therapy. Hum Gene Ther 1997; 8: 2057-68.
    • (1997) Hum Gene Ther , vol.8 , pp. 2057-2068
    • Kramm, C.M.1    Chase, M.2    Herrlinger, U.3
  • 137
    • 0028822061 scopus 로고
    • Treatment of human malignant meningiomas by G207, a replication- competent multimutated herpes simplex virus 1
    • Yazaki T, Manz HJ, Rabkin SD, Martuza RL. Treatment of human malignant meningiomas by G207, a replication-competent multimutated herpes simplex virus 1. Cancer Res 1995; 55: 4752-6.
    • (1995) Cancer Res , vol.55 , pp. 4752-4756
    • Yazaki, T.1    Manz, H.J.2    Rabkin, S.D.3    Martuza, R.L.4
  • 138
    • 0035004186 scopus 로고    scopus 로고
    • Therapeutic efficacy of G207 in a novel peripheral nerve sheath tumor model
    • Mashour GA, Moulding HD, Chahlavi A, et al. Therapeutic efficacy of G207 in a novel peripheral nerve sheath tumor model. Exp Neurol 2001; 169: 64-71.
    • (2001) Exp Neurol , vol.169 , pp. 64-71
    • Mashour, G.A.1    Moulding, H.D.2    Chahlavi, A.3
  • 139
    • 0033918250 scopus 로고    scopus 로고
    • Evaluation of ganciclovir-mediated enhancement of the antitumoral effect in oncolytic, multimutated herpes simplex virus type 1 (G207) therapy of brain tumors
    • Todo T, Rabkin SD, Martuza RL. Evaluation of ganciclovir-mediated enhancement of the antitumoral effect in oncolytic, multimutated herpes simplex virus type 1 (G207) therapy of brain tumors. Cancer Gene Ther 2000; 7: 939-46.
    • (2000) Cancer Gene Ther , vol.7 , pp. 939-946
    • Todo, T.1    Rabkin, S.D.2    Martuza, R.L.3
  • 140
    • 0036215782 scopus 로고    scopus 로고
    • Immuno-viral therapy of brain tumors by combination of viral therapy with cancer vaccination using a replication-conditional HSV
    • Toda M, Iizuka Y, Kawase T, Uyemura K, Kawakami Y. Immuno-viral therapy of brain tumors by combination of viral therapy with cancer vaccination using a replication-conditional HSV. Cancer Gene Ther 2002; 9: 356-64.
    • (2002) Cancer Gene Ther , vol.9 , pp. 356-364
    • Toda, M.1    Iizuka, Y.2    Kawase, T.3    Uyemura, K.4    Kawakami, Y.5
  • 141
    • 0033540654 scopus 로고    scopus 로고
    • Herpes simplex virus as an in situ cancer vaccine for the induction of specific anti-tumor immunity
    • Toda M, Rabkin SD, Kojima H, Martuza RL. Herpes simplex virus as an in situ cancer vaccine for the induction of specific anti-tumor immunity. Hum Gene Ther 1999; 10: 385-93.
    • (1999) Hum Gene Ther , vol.10 , pp. 385-393
    • Toda, M.1    Rabkin, S.D.2    Kojima, H.3    Martuza, R.L.4
  • 142
    • 0033589694 scopus 로고    scopus 로고
    • Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus
    • Todo T, Rabkin SD, Sundaresan P, et al. Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus. Hum Gene Ther 1999; 10: 2741-55.
    • (1999) Hum Gene Ther , vol.10 , pp. 2741-2755
    • Todo, T.1    Rabkin, S.D.2    Sundaresan, P.3
  • 143
    • 0035138174 scopus 로고    scopus 로고
    • In situ expression of soluble B7-1 in the context of oncolytic herpes simplex virus induces potent antitumor immunity
    • Todo T, Martuza RL, Dallman MJ, Rabkin SD. In situ expression of soluble B7-1 in the context of oncolytic herpes simplex virus induces potent antitumor immunity. Cancer Res 2001; 61: 153-61.
    • (2001) Cancer Res , vol.61 , pp. 153-161
    • Todo, T.1    Martuza, R.L.2    Dallman, M.J.3    Rabkin, S.D.4
  • 144
    • 0036167471 scopus 로고    scopus 로고
    • In situ cancer vaccination with a replication-conditional HSV for the treatment of liver metastasis of colon cancer
    • Endo T, Toda M, Watanabe M, et al. In situ cancer vaccination with a replication-conditional HSV for the treatment of liver metastasis of colon cancer. Cancer Gene Ther 2002; 9: 142-8.
    • (2002) Cancer Gene Ther , vol.9 , pp. 142-148
    • Endo, T.1    Toda, M.2    Watanabe, M.3
  • 145
    • 0029069681 scopus 로고
    • A viral inhibitor of peptide transporters for antigen presentation
    • Fruh K, Ahn K, Djaballah H, et al. A viral inhibitor of peptide transporters for antigen presentation. Nature 1995; 375: 415-8.
    • (1995) Nature , vol.375 , pp. 415-418
    • Fruh, K.1    Ahn, K.2    Djaballah, H.3
  • 146
    • 0029034237 scopus 로고
    • Herpes simplex virus turns off the TAP to evade host immunity
    • Hill A, Jugovic P, York I, et al. Herpes simplex virus turns off the TAP to evade host immunity. Nature 1995; 375: 411-5.
    • (1995) Nature , vol.375 , pp. 411-415
    • Hill, A.1    Jugovic, P.2    York, I.3
  • 147
    • 0032789088 scopus 로고    scopus 로고
    • Attenuated, replication-competent herpes simplex virus type 1 mutant G207: Safety evaluation of intracerebral injection in nonhuman primates
    • Hunter WD, Martuza RL, Feigenbaum F, et al. Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation of intracerebral injection in nonhuman primates. J Virol 1999; 73: 6319-26.
    • (1999) J Virol , vol.73 , pp. 6319-6326
    • Hunter, W.D.1    Martuza, R.L.2    Feigenbaum, F.3
  • 148
    • 0034035628 scopus 로고    scopus 로고
    • Attenuated, replication-competent herpes simplex virus type 1 mutant G207: Safety evaluation in mice
    • Sundaresan P, Hunter WD, Martuza RL, Rabkin SD. Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation in mice. J Virol 2000; 74: 3832-41.
    • (2000) J Virol , vol.74 , pp. 3832-3841
    • Sundaresan, P.1    Hunter, W.D.2    Martuza, R.L.3    Rabkin, S.D.4
  • 149
    • 0034567125 scopus 로고    scopus 로고
    • Viral shedding and biodistribution of G207, a multimutated, conditionally replicating herpes simplex virus type 1, after intracerebral inoculation in aotus
    • Todo T, Feigenbaum F, Rabkin SD, et al. Viral shedding and biodistribution of G207, a multimutated, conditionally replicating herpes simplex virus type 1, after intracerebral inoculation in aotus. Mol Ther 2000; 2: 588-95.
    • (2000) Mol Ther , vol.2 , pp. 588-595
    • Todo, T.1    Feigenbaum, F.2    Rabkin, S.D.3
  • 150
    • 0034922940 scopus 로고    scopus 로고
    • Preclinical safety evaluation of G207, a replication-competent herpes simplex virus type 1, inoculated intraprostatically in mice and nonhuman primates
    • Varghese S, Newsome JT, Rabkin SD, et al. Preclinical safety evaluation of G207, a replication-competent herpes simplex virus type 1, inoculated intraprostatically in mice and nonhuman primates. Hum Gene Ther 2001; 12: 999-1010.
    • (2001) Hum Gene Ther , vol.12 , pp. 999-1010
    • Varghese, S.1    Newsome, J.T.2    Rabkin, S.D.3
  • 151
    • 0034028625 scopus 로고    scopus 로고
    • A tale of two trials: Selectively replicating herpes-viruses for brain tumors
    • Kirn DH. A tale of two trials: selectively replicating herpes-viruses for brain tumors. Gene Ther 2000; 7: 815-6.
    • (2000) Gene Ther , vol.7 , pp. 815-816
    • Kirn, D.H.1
  • 152
    • 0034780803 scopus 로고    scopus 로고
    • Ionizing radiation does not alter the antitumor activity of herpes simplex virus vector G207 in subcutaneous tumor models of human and murine prostate cancer
    • Jorgensen TJ, Katz S, Wittmack EK, et al. Ionizing radiation does not alter the antitumor activity of herpes simplex virus vector G207 in subcutaneous tumor models of human and murine prostate cancer. Neoplasia 2001; 3: 451-6.
    • (2001) Neoplasia , vol.3 , pp. 451-456
    • Jorgensen, T.J.1    Katz, S.2    Wittmack, E.K.3
  • 153
    • 0033589814 scopus 로고    scopus 로고
    • Corticosteroid administration does not affect viral oncolytic activity, but inhibits antitumor immunity in replication-competent herpes simplex virus tumor therapy
    • Todo T, Rabkin SD, Chahlavi A, Martuza RL. Corticosteroid administration does not affect viral oncolytic activity, but inhibits antitumor immunity in replication-competent herpes simplex virus tumor therapy. Hum Gene Ther 1999; 10: 2869-78.
    • (1999) Hum Gene Ther , vol.10 , pp. 2869-2878
    • Todo, T.1    Rabkin, S.D.2    Chahlavi, A.3    Martuza, R.L.4
  • 154
    • 0034634863 scopus 로고    scopus 로고
    • Effects of preexisting immunity on the response to herpes simplex-based oncolytic viral therapy
    • Delman KA, Bennett JJ, Zager JS, et al. Effects of preexisting immunity on the response to herpes simplex-based oncolytic viral therapy. Hum Gene Ther 2000; 11: 2465-72.
    • (2000) Hum Gene Ther , vol.11 , pp. 2465-2472
    • Delman, K.A.1    Bennett, J.J.2    Zager, J.S.3
  • 155
    • 0032844251 scopus 로고    scopus 로고
    • Effect of prior exposure to herpes simplex virus 1 on viral vector-mediated tumor therapy in immunocompetent mice
    • Chahlavi A, Rabkin S, Todo T, Sundaresan P, Martuza R. Effect of prior exposure to herpes simplex virus 1 on viral vector-mediated tumor therapy in immunocompetent mice. Gene Ther 1999; 6: 1751-8.
    • (1999) Gene Ther , vol.6 , pp. 1751-1758
    • Chahlavi, A.1    Rabkin, S.2    Todo, T.3    Sundaresan, P.4    Martuza, R.5
  • 156
    • 7344262312 scopus 로고    scopus 로고
    • Preexisting herpes simplex virus 1 (HSV-1) immunity decreases, but does not abolish, gene transfer to experimental brain tumors by a HSV-1 vector
    • Herrlinger U, Kramm CM, Aboody-Guterman KS, et al. Preexisting herpes simplex virus 1 (HSV-1) immunity decreases, but does not abolish, gene transfer to experimental brain tumors by a HSV-1 vector. Gene Ther 2001; 5: 809-19.
    • (2001) Gene Ther , vol.5 , pp. 809-819
    • Herrlinger, U.1    Kramm, C.M.2    Aboody-Guterman, K.S.3
  • 157
    • 0034082389 scopus 로고    scopus 로고
    • Antitumor efficacy of regional oncolytic viral therapy for peritoneally disseminated cancer
    • Bennett JJ, Kooby DA, Delman K, et al. Antitumor efficacy of regional oncolytic viral therapy for peritoneally disseminated cancer. J Mol Med 2000; 78: 166-74.
    • (2000) J Mol Med , vol.78 , pp. 166-174
    • Bennett, J.J.1    Kooby, D.A.2    Delman, K.3
  • 158
    • 0036210311 scopus 로고    scopus 로고
    • Replication-selective herpes simplex virus type 1 mutant therapy of cervical cancer is enhanced by low-dose radiation
    • Blank SV, Rubin SC, Coukos G, Amin KM, Albelda SM, Molnar-Kimber KL. Replication-selective herpes simplex virus type 1 mutant therapy of cervical cancer is enhanced by low-dose radiation. Hum Gene Ther 2002; 13: 627-39.
    • (2002) Hum Gene Ther , vol.13 , pp. 627-639
    • Blank, S.V.1    Rubin, S.C.2    Coukos, G.3    Amin, K.M.4    Albelda, S.M.5    Molnar-Kimber, K.L.6
  • 159
    • 0031550775 scopus 로고    scopus 로고
    • Treatment of spontaneously arising retinoblastoma tumors in transgenic mice with an attenuated herpes simplex virus mutant
    • Brandt CR, Imesch PD, Robinson NL, et al. Treatment of spontaneously arising retinoblastoma tumors in transgenic mice with an attenuated herpes simplex virus mutant. Virology 1997; 229: 283-91.
    • (1997) Virology , vol.229 , pp. 283-291
    • Brandt, C.R.1    Imesch, P.D.2    Robinson, N.L.3
  • 160
    • 0033018401 scopus 로고    scopus 로고
    • Use of carrier cells to deliver a replication-selective herpes simplex virus-1 mutant for the intraperitoneal therapy of epithelial ovarian cancer
    • Coukos G, Makrigiannakis A, Kang EH, et al. Use of carrier cells to deliver a replication-selective herpes simplex virus-1 mutant for the intraperitoneal therapy of epithelial ovarian cancer. Clin Cancer Res 1999; 5: 1523-37.
    • (1999) Clin Cancer Res , vol.5 , pp. 1523-1537
    • Coukos, G.1    Makrigiannakis, A.2    Kang, E.H.3
  • 161
    • 0035349907 scopus 로고    scopus 로고
    • Intravesical oncolytic viral therapy using attenuated, replication-competent herpes simplex viruses G207 and Nv1020 is effective in the treatment of bladder cancer in an orthotopic syngeneic model
    • Cozzi PJ, Malhotra S, McAuliffe P, et al. Intravesical oncolytic viral therapy using attenuated, replication-competent herpes simplex viruses G207 and Nv1020 is effective in the treatment of bladder cancer in an orthotopic syngeneic model. Faseb J 2001; 15: 1306-8.
    • (2001) Faseb J , vol.15 , pp. 1306-1308
    • Cozzi, P.J.1    Malhotra, S.2    McAuliffe, P.3
  • 162
    • 0032774578 scopus 로고    scopus 로고
    • Oncolytic viral therapy for human colorectal cancer and liver metastases using a multi-mutated herpes simplex virus type-1 (G207)
    • Kooby DA, Carew JF, Halterman MW, et al. Oncolytic viral therapy for human colorectal cancer and liver metastases using a multi-mutated herpes simplex virus type-1 (G207). Faseb J 1999; 13: 1325-34.
    • (1999) Faseb J , vol.13 , pp. 1325-1334
    • Kooby, D.A.1    Carew, J.F.2    Halterman, M.W.3
  • 163
    • 0033085093 scopus 로고    scopus 로고
    • G207, modified herpes simplex virus type 1, kills human pancreatic cancer cells in vitro
    • Lee JH, Federoff HJ, Schoeniger LO. G207, modified herpes simplex virus type 1, kills human pancreatic cancer cells in vitro. J Gastrointest Surg 1999; 3: 127-31; discussion 32-3.
    • (1999) J Gastrointest Surg , vol.3 , pp. 127-131
    • Lee, J.H.1    Federoff, H.J.2    Schoeniger, L.O.3
  • 165
    • 0034980707 scopus 로고    scopus 로고
    • Therapeutic efficacy of G207, a conditionally replicating herpes simplex virus type 1 mutant, for gallbladder carcinoma in immunocompetent hamsters
    • Nakano K, Todo T, Chijiiwa K, Tanaka M. Therapeutic efficacy of G207, a conditionally replicating herpes simplex virus type 1 mutant, for gallbladder carcinoma in immunocompetent hamsters. Mol Ther 2001; 3: 431-7.
    • (2001) Mol Ther , vol.3 , pp. 431-437
    • Nakano, K.1    Todo, T.2    Chijiiwa, K.3    Tanaka, M.4
  • 166
    • 0034524154 scopus 로고    scopus 로고
    • Oncolytic viral therapy for human prostate cancer by conditionally replicating herpes simplex virus 1 vector G207
    • Oyama M, Ohigashi T, Hoshi M, Murai M, Uyemura K, Yazaki T. Oncolytic viral therapy for human prostate cancer by conditionally replicating herpes simplex virus 1 vector G207. Jpn J Cancer Res 2000; 91: 1339-44.
    • (2000) Jpn J Cancer Res , vol.91 , pp. 1339-1344
    • Oyama, M.1    Ohigashi, T.2    Hoshi, M.3    Murai, M.4    Uyemura, K.5    Yazaki, T.6
  • 167
    • 0035093631 scopus 로고    scopus 로고
    • Treatment of human renal cell carcinoma by a conditionally replicating herpes vector G207
    • Oyama M, Ohigashi T, Hoshi M, Murai M, Uyemura K, Yazaki T. Treatment of human renal cell carcinoma by a conditionally replicating herpes vector G207. J Urol 2001; 165: 1274-8.
    • (2001) J Urol , vol.165 , pp. 1274-1278
    • Oyama, M.1    Ohigashi, T.2    Hoshi, M.3    Murai, M.4    Uyemura, K.5    Yazaki, T.6
  • 168
    • 0029113725 scopus 로고
    • Treatment of experimental intracranial murine melanoma with a neuroattenuated herpes simplex virus 1 mutant
    • Randazzo BP, Kesari S, Gesser RM, et al. Treatment of experimental intracranial murine melanoma with a neuroattenuated herpes simplex virus 1 mutant. Virology 1995; 211: 94-101.
    • (1995) Virology , vol.211 , pp. 94-101
    • Randazzo, B.P.1    Kesari, S.2    Gesser, R.M.3
  • 169
    • 0032505773 scopus 로고    scopus 로고
    • Treatment of human breast cancer in a brain metastatic model by G207, a replication-competent multimutated herpes simplex virus 1
    • Toda M, Rabkin SD, Martuza RL. Treatment of human breast cancer in a brain metastatic model by G207, a replication-competent multimutated herpes simplex virus 1. Hum Gene Ther 1998; 9: 2177-85.
    • (1998) Hum Gene Ther , vol.9 , pp. 2177-2185
    • Toda, M.1    Rabkin, S.D.2    Martuza, R.L.3
  • 170
    • 0033199929 scopus 로고    scopus 로고
    • Local and systemic therapy of human prostate adenocarcinoma with the conditionally replicating herpes simplex virus vector G207
    • Walker JR, McGeagh KG, Sundaresan P, Jorgensen TJ, Rabkin SD, Martuza RL. Local and systemic therapy of human prostate adenocarcinoma with the conditionally replicating herpes simplex virus vector G207. Hum Gene Ther 1999; 10: 2237-43.
    • (1999) Hum Gene Ther , vol.10 , pp. 2237-2243
    • Walker, J.R.1    McGeagh, K.G.2    Sundaresan, P.3    Jorgensen, T.J.4    Rabkin, S.D.5    Martuza, R.L.6
  • 171
    • 20244374204 scopus 로고    scopus 로고
    • Cytokine gene transfer enhances herpes oncolytic therapy in murine squamous cell carcinoma
    • Wong RJ, Patel SG, Kim S, et al. Cytokine gene transfer enhances herpes oncolytic therapy in murine squamous cell carcinoma. Hum Gene Ther 2001; 12: 253-65.
    • (2001) Hum Gene Ther , vol.12 , pp. 253-265
    • Wong, R.J.1    Patel, S.G.2    Kim, S.3
  • 172
    • 0035300425 scopus 로고    scopus 로고
    • Biological purging of breast cancer cells using an attenuated replication-competent herpes simplex virus in human hematopoietic stem cell transplantation
    • Wu A, Mazumder A, Martuza RL, et al. Biological purging of breast cancer cells using an attenuated replication-competent herpes simplex virus in human hematopoietic stem cell transplantation. Cancer Res 2001; 61: 3009-15.
    • (2001) Cancer Res , vol.61 , pp. 3009-3015
    • Wu, A.1    Mazumder, A.2    Martuza, R.L.3
  • 173
    • 0033135055 scopus 로고    scopus 로고
    • Replication-competent, nonneuroinvasive genetically engineered herpes virus is highly effective in the treatment of therapy-resistant experimental human tumors
    • Advani SJ, Chung SM, Yan SY, et al. Replication-competent, nonneuroinvasive genetically engineered herpes virus is highly effective in the treatment of therapy-resistant experimental human tumors. Cancer Res 1999; 59: 2055-8.
    • (1999) Cancer Res , vol.59 , pp. 2055-2058
    • Advani, S.J.1    Chung, S.M.2    Yan, S.Y.3
  • 174
    • 0036169306 scopus 로고    scopus 로고
    • The use of a genetically engineered herpes simplex virus (R7020) with ionizing radiation for experimental hepatoma
    • Chung SM, Advani SJ, Bradley JD, et al. The use of a genetically engineered herpes simplex virus (R7020) with ionizing radiation for experimental hepatoma. Gene Ther 2002; 9: 75-80.
    • (2002) Gene Ther , vol.9 , pp. 75-80
    • Chung, S.M.1    Advani, S.J.2    Bradley, J.D.3
  • 175
    • 0034856629 scopus 로고    scopus 로고
    • A novel approach to cancer therapy using an oncolytic herpes virus to package amplicons containing cytokine genes
    • Carew JF, Kooby DA, Halterman MW, Kim SH, Federoff HJ, Fong Y. A novel approach to cancer therapy using an oncolytic herpes virus to package amplicons containing cytokine genes. Mol Ther 2001; 4: 250-6.
    • (2001) Mol Ther , vol.4 , pp. 250-256
    • Carew, J.F.1    Kooby, D.A.2    Halterman, M.W.3    Kim, S.H.4    Federoff, H.J.5    Fong, Y.6
  • 177
    • 0032080376 scopus 로고    scopus 로고
    • In situ cancer vaccination: An IL-12 defective vector/replication- competent herpes simplex virus combination induces local and systemic antitumor activity
    • Toda M, Martuza RL, Kojima H, Rabkin SD. In situ cancer vaccination: an IL-12 defective vector/replication-competent herpes simplex virus combination induces local and systemic antitumor activity. J Immunol 1998; 160: 4457-64.
    • (1998) J Immunol , vol.160 , pp. 4457-4464
    • Toda, M.1    Martuza, R.L.2    Kojima, H.3    Rabkin, S.D.4
  • 178
    • 0035432783 scopus 로고    scopus 로고
    • Combination vascular delivery of herpes simplex oncolytic viruses and amplicon mediated cytokine gene transfer is effective therapy for experimental liver cancer
    • Zager JS, Delman KA, Malhotra S, et al. Combination vascular delivery of herpes simplex oncolytic viruses and amplicon mediated cytokine gene transfer is effective therapy for experimental liver cancer. Mol Med 2001; 7: 561-8.
    • (2001) Mol Med , vol.7 , pp. 561-568
    • Zager, J.S.1    Delman, K.A.2    Malhotra, S.3
  • 179
    • 0032535495 scopus 로고    scopus 로고
    • Enhanced tumor cell killing in the presence of ganciclovir by herpes simplex virus type 1 vector-directed coexpression of human tumor necrosis factor-alpha and herpes simplex virus thymidine kinase
    • Moriuchi S, Oligino T, Krisky D, et al. Enhanced tumor cell killing in the presence of ganciclovir by herpes simplex virus type 1 vector-directed coexpression of human tumor necrosis factor-alpha and herpes simplex virus thymidine kinase. Cancer Res 1998; 58: 5731-7.
    • (1998) Cancer Res , vol.58 , pp. 5731-5737
    • Moriuchi, S.1    Oligino, T.2    Krisky, D.3
  • 180
    • 0035076462 scopus 로고    scopus 로고
    • Combination suicide/ cytokine gene therapy as adjuvants to a defective herpes simplex virus-based cancer vaccine
    • Toda M, Martuza RL, Rabkin SD. Combination suicide/ cytokine gene therapy as adjuvants to a defective herpes simplex virus-based cancer vaccine. Gene Ther 2001; 8: 332-9.
    • (2001) Gene Ther , vol.8 , pp. 332-339
    • Toda, M.1    Martuza, R.L.2    Rabkin, S.D.3
  • 181
    • 0033222263 scopus 로고    scopus 로고
    • HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: Part I. HSV-1 structure, replication and pathogenesis
    • Jacobs A, Breakefield XO, Fraefel C. HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part I. HSV-1 structure, replication and pathogenesis. Neoplasia 1999; 1: 387-401.
    • (1999) Neoplasia , vol.1 , pp. 387-401
    • Jacobs, A.1    Breakefield, X.O.2    Fraefel, C.3
  • 182
    • 0033222932 scopus 로고    scopus 로고
    • HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: Part II. Vector systems and applications
    • Jacobs A, Breakefield XO, Fraefel C. HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part II. Vector systems and applications. Neoplasia 1999; 1: 402-16.
    • (1999) Neoplasia , vol.1 , pp. 402-416
    • Jacobs, A.1    Breakefield, X.O.2    Fraefel, C.3
  • 183
    • 0025975357 scopus 로고
    • Herpes simplex virus type 1 deletion variants 1714 and 1716 pinpoint neurovirulence-related sequences in Glasgow strain 17+ between immediate early gene 1 and the 'a' sequence
    • MacLean AR, ul-Fareed M, Robertson L, Harland J, Brown SM. Herpes simplex virus type 1 deletion variants 1714 and 1716 pinpoint neurovirulence-related sequences in Glasgow strain 17+ between immediate early gene 1 and the 'a' sequence. J Gen Virol 1991; 72: 631-9.
    • (1991) J Gen Virol , vol.72 , pp. 631-639
    • MacLean, A.R.1    Ul-Fareed, M.2    Robertson, L.3    Harland, J.4    Brown, S.M.5
  • 184
    • 0025688373 scopus 로고
    • Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture
    • Chou J, Kern ER, Whitley RJ, Roizman B. Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture. Science 1990; 250: 1262-6.
    • (1990) Science , vol.250 , pp. 1262-1266
    • Chou, J.1    Kern, E.R.2    Whitley, R.J.3    Roizman, B.4
  • 185
    • 0035933088 scopus 로고    scopus 로고
    • Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing
    • Todo T, Martuza RL, Rabkin SD, Johnson PA. Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing. Proc Natl Acad Sci USA 2001; 98: 6396-401.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6396-6401
    • Todo, T.1    Martuza, R.L.2    Rabkin, S.D.3    Johnson, P.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.