Inclusion of the herpes simplex thymidine kinase gene in a replicating adenovirus does not augment antitumor efficacy

Gene Therapy

Volumn 8, Issue 12, 2001, Pages 946-953

  Lambright, E S ^a   Amin, K ^a   Wiewrodt, R ^a   Force, S D ^a   Lanuti, M ^a   Propert, K J ^a   Litzky, L ^a   Kaiser, L R ^a   Albelda, S M ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Adenovirus; Cancer gene therapy; Gene therapy; Herpes simplex thymidine kinase; Replicating adenovirus

Indexed keywords

GANCICLOVIR; THYMIDINE KINASE; VIRUS PROTEIN; VIRUS VECTOR;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER; CELL KILLING; CONTROLLED STUDY; FEMALE; GENE CONSTRUCT; GENE DELETION; GENE THERAPY; GENETIC TRANSDUCTION; HERPES SIMPLEX; HUMAN; HUMAN CELL; IN VITRO STUDY; INJECTION; MOUSE; NONHUMAN; PERITONEUM TUMOR; PRIORITY JOURNAL; PROMOTER REGION; SUICIDE GENE; TRANSGENE; TUMOR CELL; VIRUS REPLICATION;

ADENOVIRIDAE; ANALYSIS OF VARIANCE; ANIMALS; ANTIVIRAL AGENTS; FEMALE; GANCICLOVIR; GENE THERAPY; GENETIC VECTORS; INJECTIONS, INTRALESIONAL; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; MICE, SCID; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; SIMPLEXVIRUS; THYMIDINE KINASE; TRANSDUCTION, GENETIC; VIRUS REPLICATION;

EID: 0034956825     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301489     Document Type: Article

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