메뉴 건너뛰기




Volumn 59, Issue 21, 1999, Pages 5412-5416

Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; PROTEIN TYROSINE KINASE INHIBITOR; SEMAXANIB; SU 6688; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR;

EID: 0033231069     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (329)

References (15)
  • 1
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rhuematoid and other disease
    • Folkman, J. Angiogenesis in cancer, vascular, rhuematoid and other disease. Nat. Med., 1: 27-31, 1995.
    • (1995) Nat. Med. , vol.1 , pp. 27-31
    • Folkman, J.1
  • 2
    • 84970070220 scopus 로고
    • Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer
    • Takahashi, Y., Kitadai, Y., Bucana, C. D., Cleary, K. R., and Ellis, L. M. Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res., 55: 3964-3968, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 3964-3968
    • Takahashi, Y.1    Kitadai, Y.2    Bucana, C.D.3    Cleary, K.R.4    Ellis, L.M.5
  • 3
    • 0031915348 scopus 로고    scopus 로고
    • Regulation of distinct steps of angiogenesis by different angiogenic molecules
    • Kumar, R., Yoneda, J., Bucana, C. D., and Fidler, I. J. Regulation of distinct steps of angiogenesis by different angiogenic molecules. Int. J. Oncol., 12: 749-757, 1998.
    • (1998) Int. J. Oncol. , vol.12 , pp. 749-757
    • Kumar, R.1    Yoneda, J.2    Bucana, C.D.3    Fidler, I.J.4
  • 4
    • 0028808015 scopus 로고
    • Platelet-derived growth factor-B increases colon cancer cell growth in vivo by a paracrine effect
    • Hsu, S., Huang, F., and Friedman, E. Platelet-derived growth factor-B increases colon cancer cell growth in vivo by a paracrine effect. J. Cell, Physiol., 165: 239-245, 1995.
    • (1995) J. Cell, Physiol. , vol.165 , pp. 239-245
    • Hsu, S.1    Huang, F.2    Friedman, E.3
  • 5
    • 0029855311 scopus 로고    scopus 로고
    • Protein tyrosine kinase receptors
    • Heldin, C. H. Protein tyrosine kinase receptors. Cancer Surv., 27: 7-24, 1996.
    • (1996) Cancer Surv. , vol.27 , pp. 7-24
    • Heldin, C.H.1
  • 6
    • 0032437411 scopus 로고    scopus 로고
    • Targeting VEGF in anti-angiogenic and anti-tumour therapy: Where are we now?
    • Leenders, W. P. J. Targeting VEGF in anti-angiogenic and anti-tumour therapy: where are we now? Int. J. Exp. Pathol., 79: 339-346, 1998.
    • (1998) Int. J. Exp. Pathol. , vol.79 , pp. 339-346
    • Leenders, W.P.J.1
  • 8
    • 0032893263 scopus 로고    scopus 로고
    • SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types
    • Fong, T. A., Shawver, L. K., Sun, L., Tang, C., App, H., Powell, T. J., Kim, Y. H., Schreck, R., Wang, X., Risau, W., Ullrich, A., Hirth, K. P., and McMahon, G. SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types. Cancer Res., 59: 99-106, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 99-106
    • Fong, T.A.1    Shawver, L.K.2    Sun, L.3    Tang, C.4    App, H.5    Powell, T.J.6    Kim, Y.H.7    Schreck, R.8    Wang, X.9    Risau, W.10    Ullrich, A.11    Hirth, K.P.12    McMahon, G.13
  • 9
    • 0028342711 scopus 로고
    • Organ-specific modulation of steady-state mdr-1 gene expression and drug resistance in murine colon cancer cells
    • Dong, Z., Radinsky, R., Fan, D., Tsan, R., Bucana, C. D., Wilmanns, C., and Fidler, I. J. Organ-specific modulation of steady-state mdr-1 gene expression and drug resistance in murine colon cancer cells. J. Natl. Cancer Inst., 86: 913-920, 1994.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 913-920
    • Dong, Z.1    Radinsky, R.2    Fan, D.3    Tsan, R.4    Bucana, C.D.5    Wilmanns, C.6    Fidler, I.J.7
  • 10
    • 0026846928 scopus 로고
    • The role of angiogenesis in tumor growth
    • Folkman, J. The role of angiogenesis in tumor growth. Semin. Cancer Biol., 3:65-71, 1992.
    • (1992) Semin. Cancer Biol. , vol.3 , pp. 65-71
    • Folkman, J.1
  • 12
    • 0033134716 scopus 로고    scopus 로고
    • Antiangiogenic gene therapy in a rat glioma model using a dominant-negative vascular endothelial growth factor receptor 2
    • Machein, M. R., Risau, W., and Plate, K. H. Antiangiogenic gene therapy in a rat glioma model using a dominant-negative vascular endothelial growth factor receptor 2. Hum. Gene Ther., 10: 1117-1128, 1999.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 1117-1128
    • Machein, M.R.1    Risau, W.2    Plate, K.H.3
  • 13
    • 0033018871 scopus 로고    scopus 로고
    • Efficacy and concentration-response of murine anti-VEGF monoclonal antibody in tumor-bearing mice and extrapolation to humans
    • Mordenti, J., Thomsen, K., Licko, V., Chen, H., Meng, Y. G., and Ferrara, N. Efficacy and concentration-response of murine anti-VEGF monoclonal antibody in tumor-bearing mice and extrapolation to humans. Toxicol. Pathol., 27: 14-21, 1999.
    • (1999) Toxicol. Pathol. , vol.27 , pp. 14-21
    • Mordenti, J.1    Thomsen, K.2    Licko, V.3    Chen, H.4    Meng, Y.G.5    Ferrara, N.6
  • 14
    • 0028951043 scopus 로고
    • Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
    • Holmgren, L., O'Reilly, M. S., and Folkman, J. Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression Nat. Med., 1: 149-153, 1995.
    • (1995) Nat. Med. , vol.1 , pp. 149-153
    • Holmgren, L.1    O'Reilly, M.S.2    Folkman, J.3
  • 15
    • 0032557564 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and Al in vascular endothelial cells
    • Gerber, H. P., Dixit, V., and Ferrara, N. Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and Al in vascular endothelial cells. J. Biol. Chem., 273: 13313-13316, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 13313-13316
    • Gerber, H.P.1    Dixit, V.2    Ferrara, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.