Expression of cell-associated isoform of vascular endothelial growth factor 189 and its prognostic relevance in non-small cell lung cancer

International Journal of Oncology

Volumn 12, Issue 3, 1998, Pages 541-544

  Oshika, Yoshiro ^a   Nakamura, Masato ^a   Tokunaga, Tetsuji ^a   Ozeki, Yuichi ^b   Fukushima, Yoshitaka ^a   Hatanaka, Hiroyuki ^a   Abe, Yoshiyuki ^a   Yamazaki, Hitoshi ^a   Kijima, Hiroshi ^a   Tamaoki, Norikazu ^a   Ueyama, Yoshito ^a  

^a TOKAI UNIVERSITY   (Japan)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

Non small cell lung cancer; Prognosis; VEGF189

Indexed keywords

CELL PROTEIN; ISOPROTEIN; MESSENGER RNA; VASCULOTROPIN;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 13144260681     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.12.3.541     Document Type: Article

References (25)

1. Gospodarowicz DJ, Abraham JA and Schilling J: Isolation and characterization of a vascular endothelial cell mitogen produced by pituitary-derived folliculo stellate cells. Proc Natl Acad Sci USA 86: 7311-7315, 1989.
2. Keck PJ, Hauser SD, Krivi G, Sanzo K, Warren T, Feder J and Connolly DT: Vascular permiability factor, an endothelial cell mitogen related to PDGF. Science 246: 1309-1312, 1989.
3. Plate KH, Breier G, Weich HA and Risau W: Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 359: 845-848, 1992.
4. Asano M, Yukita A, Matsumoto T, Kondo S and Suzuki H: Inhibition of tumor growth and metastasis by an immunoneutralizing monoclonal antibody to human vascular endothelial growth factor/vascular permiability factor 121. Cancer Res 55: 5296-5301, 1995.
5. Cheng SY, Huang HJ, Nagane M, Ji XD, Wang D, Shih CC, Arap W, Huang CM and Cavenee WK: Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor. Proc Natl Acad Sci USA 93: 8502-8507, 1996.
6. Ramakrishnan S, Olson TA, Bautch VL and Mohanraj D: Vascular endothelial growth factor-toxin conjugate specifically inhibits KDR/flk-1-positive endothelial cell proliferation in vitro and angiogenesis in vivo. Cancer Res 56: 1324-1330, 1996.
7. Takahashi Y, Kitadai Y, Bucana CD, Cleary RK and Ellis LM: Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res 55: 3964-3968, 1995.
8. Brown LF, Berse B, Jackman RW, Tognazzi K, Guildi A, Dvorak H, Senger D, Connonlly J and Schnitt S: Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer. Hum Pathol 26: 86-91, 1995.
9. Berkman RA, Merril MJ, Reinhold WC, Monacci WT, Saxena A, Clark WC, Robertson JT, Ali IU and Oldfield EH: Expression of the vascular permeability factor/vascular endothelial growth gene in central nervous system neoplasms. J Clin Invest 91: 153-159, 1993.
10. Boocock CA, Charnock-Jones DS, Sharkey AM, McLaren J, Barker PJ, Wright KA, Twentyman PR and Smith SK: Expression of vascular endothelial growth factor and its receptors fit and KDR in ovarian carcinoma. J Natl Cancer Inst 87: 506-516, 1995.
11. Suzuki K, Hayashi N, Miyamoto Y, Yamamoto M, Ohkawa K, Ito Y, Sasaki Y, Yamaguchi Y, Nakase H, Noda K, Enomoto N, Arai K, Yamada Y, Yoshihara H, Tujimura T, Kawano K, Yoshikawa K and Kamada T: Expression of vascular permeability factor/vascular endothelial growth factor in human hepatocellular carcinoma. Cancer Res 56: 3004-3009, 1996.
12. Berse B, Brown LF, Vav De Water L, Dvorak HF and Senger DR: Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors. Mol Biol Cell 3: 211-220, 1992.
13. Inoue K, Ozcki Y, Suganuma Y, Sugiura Y and Tanaka S: Vascular endothelial growth factor expression in primary esophageal squamous cell carcinoma. Association with angiogenesis and tumor progression. Cancer 79; 206-213, 1997.
14. Volm M, Koomägi R and Mattern J: Prognostic value of vascular endothelial growth factor and its receptor flt-1 in squamous cell lung cancer. Int J Cancer 74: 64-68, 1997.
15. Dvorak HF, Brown LF, Detmar M and Dvorak AM: Vascular permiability factor/vascular endothelial growth factor, microvascular hyperpermiability, and angiogenesis. Am J Pathol 146: 1029-1039, 1995.
16. Houck KA, Leung DW, Rawland AM and Winer J: Dual regulation of vascular endothelial growth factor bioavailability by genetic proteolytic machenisms. J Biol Chem 267:26031-26037, 1992.
17. Viglietto G, Romano A, Maglione D, Rambaldi M, Paoletti I, Lago CT, Califano D, Monaco C, Mineo A, Santelli G, Manzo G, Botti G, Chiappetta G and Persico MG: Neovascularization in human germ cell tumors correlates with a marked increase in the expression of the vascular endothelial growth factor but not the placenta-derived growth factor. Oncogene 13: 577-587, 1996.
18. Tokunaga T, Oshika Y, Abe Y, Ozeki Y, Sadahiro S, Kijima H, Tsuchida T, Yamazaki H, Ueyama Y, Tamaoki N and Nakamura M: Vascular endothelial growth factor (VEGF) mRNA isoform expression pattern is correlated with liver metastasis and poor prognosis in colon cancer. Br J Cancer (In press).
19. Folkman J: Tumor angiogenesis: therapeutic implications. N Eng J Med 285: 1182-1186, 1971.
20. Paley PJ, Staskus KA, Gebhard K, Mohanraj D, Twiggs LB, Carson LF and Ramakrishnan S: Vascular endothelial growth factor expression in early ovarian carcinoma. Cancer 80: 98-106, 1997.
21. Gasparini G, Toi M, Gion M, Verderio P, Dittadi R, Hanatani M, Matsubara I, Vinante O, Bonoldi E, Boracchi P, Gatti C, Suzuki H and Tominaga T: Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma. J Natl Cancer Inst 89: 139-147, 1997.
22. Obermair A, Kohlberger P, Bancher-Todesca D, Tempfer C, Sliutz G, Leodolter S, Reinthaller A, Kainz C, Breitenecker G and Gotsch G: Influence of microvessel density and vascular endothelial permiability factor/vascular endothelial growth factor expression on prognosis in vulvar cancer. Gynecol Oncol 63: 204-209, 1996.
23. Shweiki D, Itin A, Soffer D and Keishet E: Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359: 843-845, 1992.
24. Kamat BR, Brown LF, Manseau EJ, Senger DR and Dvorak HF: Expression of vascular permiability factor/vascular endothelial growth factor by human granulosa and theca lutein cells: role in corpus luteum development. Am J Pathol 146: 157-165, 1995.
25. Plouët J, Moro F, Bertagnolli S, Coldeboeuf N, Mazarguil H, Clamens S and Bayard F: Extracellular cleavage of the vascular endothelial growth factor 189-amino acid form by urokinase is required for its mitogenic effect. J Biol Chem 272: 13390-13396, 1997.