Oxidative stress and gene expression: The AP-1 and NF-κB connections

BioFactors

Volumn 15, Issue 2-4, 2001, Pages 87-89

  Karin, Michael ^a   Takahashi, Takayuki ^a   Kapahi, Pankaj ^a   Delhase, Mireille ^a   Chen, Yi ^a   Makris, Constantin ^a   Rothwarf, David ^a   Baud, Véronique ^a   Natoli, Goiacchino ^a   Guido, Francesco ^a   Li, Nanxin ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC TRIOXIDE; BIOLOGICAL MARKER; HYDROGEN PEROXIDE; I KAPPA B; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PROTEIN C JUN; PROTEIN FOS; PROTEIN SUBUNIT; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CATALYSIS; CELL DIFFERENTIATION; CELL STIMULATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; INFLAMMATION; LEUKEMIA CELL LINE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

EID: 18344378407     PISSN: 09516433     EISSN: None     Source Type: Journal    
DOI: 10.1002/biof.5520150207     Document Type: Article

References (13)

1. A cytokine responsive IκB kinase that activates the transcription factor NF-κB
2. The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation
3. IKKγ is an essential regulatory subunit of the IκB kinase complex
4. Ionizing radiation and short wavelength UV activate NF-κB through two distinct mechanisms
5. Is NF-κB the sensor of oxidative stress?
6. Positive and negative regulation of IκB kinase activity through IKKβ subunit phosphorylation
7. Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of the IκB kinase
8. Bridging the gap: Composition, regulation and physiological function of the I kappa B kinase complex
9. Signaling by proinflammatory cytokines: Oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain
10. JNK2 and IKKβ are required for activating the innate response to viral infection
11. The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase
12. The regulation of AP-1 activity by mitogen-activated protein kinases
13. The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest