Modulation of hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an rb-and schedule-dependent manner

Clinical Cancer Research

Volumn 7, Issue 8, 2001, Pages 2228-2236

  Münster, Pamela N ^a   Basso, Andrea ^a   Solit, David ^a   Norton, Larry ^a   Rosen, Neal ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

17 ALLYLAMINOGELDANAMYCIN; ANSAMYCIN DERIVATIVE; CASPASE 3; CASPASE 9; DOXORUBICIN; HEAT SHOCK PROTEIN 90; PACLITAXEL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL CYCLE G1 PHASE; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; SENSITIZATION;

ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BENZOQUINONES; BREAST NEOPLASMS; CASPASE 3; CASPASE 9; CASPASES; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG SYNERGISM; ENZYME ACTIVATION; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; MITOSIS; PACLITAXEL; RETINOBLASTOMA PROTEIN; RIFABUTIN; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0034890377     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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