Tetrahydrocannabinol-induced neurotoxicity depends on CB 1 receptor-mediated c-Jun N-terminal kinase activation in cultured cortical neurons

British Journal of Pharmacology

Volumn 140, Issue 3, 2003, Pages 547-557

  Downer, Eric J ^a   Fogarty, Marie P ^a   Campbell, Veronica A ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

9 Tetrahydrocannabinol; Antisense; Apoptosis; Bax; C Jun N terminal kinase; Caspase 3

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CANNABINOID 1 RECEPTOR; CANNABINOID 1 RECEPTOR ANTAGONIST; CASPASE 3; GUANINE NUCLEOTIDE BINDING PROTEIN; PERTUSSIS TOXIN; RECEPTOR BLOCKING AGENT; STRESS ACTIVATED PROTEIN KINASE; TETRAHYDROCANNABINOL; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CANNABIS ADDICTION; CONTROLLED STUDY; DNA DEGRADATION; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; NEUROTOXICITY; NEWBORN; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; ENZYME ACTIVATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; RATS; RATS, WISTAR; RECEPTOR, CANNABINOID, CB1; TETRAHYDROCANNABINOL;

EID: 0142184948     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705464     Document Type: Article

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