Comparison between the timing of JNK activation, c-Jun phosphorylation, and onset of death commitment in sympathetic neurones

Journal of Neurochemistry

Volumn 69, Issue 2, 1997, Pages 550-561

  Virdee, Kanwar ^a   Bannister, Andrew J ^b   Hunt, Stephen P ^c   Tolkovsky, Aviva M ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

Apoptosis; c Jun; MAP kinase; Signal transduction; Stress activated protein kinase; Superior cervical ganglion; Trk

Indexed keywords

GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ASSAY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; NERVE CELL CULTURE; NERVE CELL NECROSIS; NONHUMAN; ONCOGENE C JUN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; STRESS; SUPERIOR CERVICAL GANGLION; SYMPATHETIC NERVE CELL;

ANIMALIA;

EID: 0030751556     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.69020550.x     Document Type: Article

References (42)

1. Adler V., Schaffer A., Kim J., Dolan L., and Ronai Z. (1995) UV irradiation and heat shock mediated JNK activation via alternate pathways. J. Biol. Chem. 270, 26071-26077.
2. Bannister A. J., Gottlieb T. M., Kouzarides T., and Jackson S. P. (1993) c-Jun is phosphorylated by the DNA-dependent protien kinase in vitro; definition of the minimal kinase recognition motif. Nucleic Acids Res. 21, 1289-1295.
3. Barbin G., Manthorpe M., Varon S. (1984) Purification of the chick eye ciliary neuronotrophic factor. J. Neurochem. 43, 1468-1478.
4. Binetruy B., Smeal T., and Karin M. (1991) Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. Nature 351, 122-127.
5. Buckmaster E. A., Nobes C. D., Edwards S. N., and Tolkovsky A. M. (1991) Nerve growth factor is required for the induction of c-fos immunoreactivity by serum, depolarisation, cylic AMP or trauma in cultured rat sympathetic neurons. Eur J. Neurosci. 3, 698-707.
6. Burnham P., Louis J.-C., Magal E., and Varon S. (1994) Effects of ciliary neurotrophic factor on the survival and response to nerve growth factor of cultured rat sympathetic neurons. Dev. Biol. 161, 96-106.
7. Cowley S., Paterson H., Kemp P., Marshall C. J. (1994) Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77, 841-852.
8. Creedon D. J., Johnson E. M., and Lawrence J. C. (1996) Mitogen-activated protein kinase-independent pathways mediate the effects of nerve growth-factor and cAMP on neuronal survival. J. Biol. Chem. 271, 20713-20718.
9. Davis R. J. (1994) MAPKs - new JNK expands the group. Trends Biochem. Sci. 19, 470-473.
10. Defelipe C. and Hunt S. P. (1994) The differential control of c-Jun expression in regenerating sensory neurons and their associated glial cells. J. Neurosci. 14, 2911-2923.
11. Dérijard B., Hibi H., Wu I.-H., Barret T., Su B., Deng T., Karin M., and Davis R. J. (1994) JNK1 - a protein-kinase stimulated by UV-light and Ha-ras that binds and phosphorylates the c-Jun activation domain. Cell 76, 1025-1037.
12. Edwards S. N. and Tolkovsky A. M. (1994) Characterisation of apoptosis in cultured rat sympathetic neurons after nerve growth factor (NGF) withdrawal. J. Cell Biol. 124, 537-546.
13. Edwards S. N., Buckmaster A. E., and Tolkovsky A. M. (1991) The death programme in sympathetic neurons can be suppressed at the posttranslational level by nerve growth factor, cylic AMP, and depolarization. J. Neurochem. 57, 2140-2143.
14. Estus S., Zaks W. J., Freeman R. S., Gruda M., Bravo R., and Johnson E. M. (1994) Altered gene expression in neurons during programmed cell death; identification of c-Jun as necessary for neuronal apoptosis. J. Cell Biol. 127, 1717-1727.
15. Ham J., Babij C., Whitfield J., Pfarr C. M., Lallemand D., Yaniv M., and Rubin L. L. (1995) A c-jun dominant-negative mutant protects sympathetic neurons againts programmmed cell death. Neuron 14, 927-939.
16. Hawrot E. and Patterson P. H. (1979) Long-term culture of dissociated sympathetic neurons. Methods Enzymol. 58, 574-584.
17. Hibi M., Lin A., Smeal T., Minden A., and Karin M. (1993) Identification of an oncoprotein-and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev. 7, 2135-2148.
18. Hsueh Y.-P. and Lai M.-Z. (1995) c-Jun N-terminal kinase but not mitogen-activated protein kinase is sensitive to cAMP inhibition in T lymphocytes. J. Biol. Chem. 270, 18094-18098.
19. Jenkins R., McMahon S. B., Bond A. B., and Hunt S. P. (1993) Expression of c-Jun as a response to dorsal-root and peripheranerve section in damaged and adjacent intact primary sensory neurons in the rat. Eur. J. Neurosci. 5, 751-759.
20. Kotzbauer P. T., Lampe P. A., Estus S., Milbrandt J., and Johnson E. M. (1994) Postnatal development of survival responsiveness in rat sympathetic neurons to leukemia inhibitory factor and ciliary neurotrophic factor. Neuron 12, 763-773.
21. Kumar S. (1995) ICE-like proteases in apoptosis. Trends Biochem. Sci. 20, 198-202.
22. Kyriakis J. M. and Avruch J. (1996) Sounding the alarm: protein kinase cascades activated by stress and inflammation. J. Biol. Chem. 271, 24313-24316.
23. Kyriakis J. M., Banerjee P., Nikolakaki E., Dai T., Rubie E. A., Ahmad M. F., Avruch J., and Woodgett J. R. (1994) The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369, 156-160.
24. Leah J. D., Herdegen T., and Bravo R. (1991) Selective expression of Jun proteins following axotomy and axonal-transport block in peripheral-nerves in the rat - evidence for a role in the regeneration process. Brain Res. 566, 198-207.
25. Levi-Montalcini R. (1965) The nerve growth factor: its mode of action on sensory and sympathetic nerve cells. Harvey Lect. 60, 217-259.
26. Liu Z., Hsu H., Goeddel D. V., and Karin M. (1996) Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-KB activation prevents cell death. Cell 87, 565-576.
27. Livingstone C., Patel G., and Jones N. (1995) ATF-2 contains a phosphorylation-dependent transcriptional domain. EMBO J. 14, 1785-1797.
28. Minden A., Lin A., McMahon M., Lange-Carter C., Dérijard B., Davis R. J., Johnson G. L., and Karin M. (1994) Differential activation of ERK and JNK mitogen-activated protein-kinases by Raf-1 and MEKK. Science 266, 1719-1723.
29. Nicholson D. W., Ali A., Thornberry N. A., Vaillancourt J. P., Ding C. K., Gallant M., Gareau Y., Griffin P. R., Labelle M., Lazebnik Y. A., Munday N. A., Raju S. M., Smulson M. E., Yamin T.-T., Yu V. L., and Miller D. (1995) Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376, 37-43.
30. Nobes C. D. and Tolkovsky A. M. (1995) Neutralizing anti-p21ras Fabs suppress rat sympathetic neuron survival induced by NGF, LIF, CNTF and cAMP. Eur. J. Neurosci. 7, 344-350.
31. Nobes C. D., Reppas J. P., Markus A., and Tolkovsky A. M. (1996) Active p21Ras is sufficient for rescue of NGF-dependent rat sympathetic neurons. Neuroscience 70, 1067-1079.
32. Pulverer B. J., Kyriakis J. M., Avruch J., Nikolakaki E., and Woodgett J. R. (1991) Phosphorylation of c-jun mediated by MAP kinases. Nature 353, 670-674.
33. Rehen S. K., Varella M. H., Freitas F. G., Moraes M. O., and Linden R. (1996) Contrasting effects of protein-synthesis inhibition and of cyclic-AMP on apoptosis in the developing retina. Development 122, 1439-1448.
34. Rofflertarlov S., Brown J. J. G., Tarlov E., Stolarov J., Chapman D. L., Alexiou M., and Papaioannou V. E. (1996) Programmed cell-death in the absence of c-fos and c-jun. Development 122, 1-9.
35. Rydel R. E. and Greene L. A. (1988) cAMP analogs promote survival and neunte outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor. Proc. Natl. Acad. Sci. USA 85, 1257-1261.
36. Saadat S., Sendtner M., and Rohrer H. (1989) Ciliary neurotrophic factor induces cholinergic differentiation of rat sympathetic neurons in culture. J. Cell Biol. 108, 1807-1816.
37. Sluss H. K., Barrett T., Derijard B., and Davis R. J. (1994) Signal transduction by tumor necrosis factor mediated by JNK protein kinases. Mol. Cell. Biol. 14, 8376-8384.
38. Smeal T., Binetruy B., Mercola D., Birrer M., and Karin M. (1991) Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature 354, 494-496.
39. Smith D. B. and Johnson K. S. (1988) Single-step purification of polypeptides expressed in Escherichia-coli as fusions with glutathione-S-transferase. Gene 67, 31-40.
40. Virdee K. and Tolkovsky A. M. (1995) Activation of p44 and p42 MAP kinases is not essential for the survival of rat sympathetic neurons. Eur. J. Neurosci. 7, 2159-2169.
41. Virdee K. and Tolkovsky A. M. (1996) Inhibition of p42 and p44 mitogen-activated protein kinase activity by PD98059 does not suppress nerve growth factor-induced survival of sympathetic neurons. J. Neurochem. 67, 1801-1805.
42. Xia Z., Dickens M., Raingeaud J., Davis R. J., and Greenberg M. E. (1995) Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270, 1326-1331.