-
1
-
-
0035685449
-
Complete characterization of the human ABC gene family
-
Dean M, Allikmets R. Complete characterization of the human ABC gene family. J Bioenerg Biomembr 2001; 33: 475-479.
-
(2001)
J Bioenerg Biomembr
, vol.33
, pp. 475-479
-
-
Dean, M.1
Allikmets, R.2
-
2
-
-
0034767050
-
Drug transporters and their role in multidrug resistance of neoplastic cells
-
Kvackajova-Kisucka J, Barancik M, Breier A. Drug transporters and their role in multidrug resistance of neoplastic cells. Gen Physiol Biophys 2001; 20: 215-237.
-
(2001)
Gen Physiol Biophys
, vol.20
, pp. 215-237
-
-
Kvackajova-Kisucka, J.1
Barancik, M.2
Breier, A.3
-
3
-
-
0035682486
-
MRP subfamily transporters and resistance to anticancer agents
-
Kruh GD, Zeng H, Rea PA, et al. MRP subfamily transporters and resistance to anticancer agents. J Bioenerg Biomembr 2001; 33: 493-501.
-
(2001)
J Bioenerg Biomembr
, vol.33
, pp. 493-501
-
-
Kruh, G.D.1
Zeng, H.2
Rea, P.A.3
-
4
-
-
0034795256
-
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
-
Zhou S, Schuetz JD, Bunting KD, et al. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nature Med 2001; 7: 1028-1034.
-
(2001)
Nature Med
, vol.7
, pp. 1028-1034
-
-
Zhou, S.1
Schuetz, J.D.2
Bunting, K.D.3
-
5
-
-
13044249156
-
A multidrug resistance transporter from human MCF-7 breast cancer cells
-
Doyle LA, Yang W, Abruzzo LV, et al. A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci USA 1998; 95: 15665-15670.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15665-15670
-
-
Doyle, L.A.1
Yang, W.2
Abruzzo, L.V.3
-
6
-
-
0034081847
-
The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)
-
Litman T, Brangi M, Hudson E, et al. The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2). J Cell Sci 2000; 113: 2011-2021.
-
(2000)
J Cell Sci
, vol.113
, pp. 2011-2021
-
-
Litman, T.1
Brangi, M.2
Hudson, E.3
-
7
-
-
0034728768
-
The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane
-
Rocchi E, Khodjakov A, Volk EL, et al. The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane. Biochem Biophys Res Commun 2000; 271: 42-46.
-
(2000)
Biochem Biophys Res Commun
, vol.271
, pp. 42-46
-
-
Rocchi, E.1
Khodjakov, A.2
Volk, E.L.3
-
8
-
-
0037164703
-
Functional analysis of candidate ABC transporter proteins for sitosterols transport
-
Albrecht C, Elliott JI, Sardini A, et al. Functional analysis of candidate ABC transporter proteins for sitosterols transport. Biochim Biophys Acta 2002; 1567: 133-142.
-
(2002)
Biochim Biophys Acta
, vol.1567
, pp. 133-142
-
-
Albrecht, C.1
Elliott, J.I.2
Sardini, A.3
-
9
-
-
0027855043
-
In vivo and in vitro characterization of long-term repopulating primitive hematopoietic cells isolated by sequential Hoechst 33342-rhodamine 123 FACS selection
-
Wolf NS, Kone A, Priestley GV, Bartelmez SH. In vivo and in vitro characterization of long-term repopulating primitive hematopoietic cells isolated by sequential Hoechst 33342-rhodamine 123 FACS selection. Exp Hematol 1993; 21: 614-622.
-
(1993)
Exp Hematol
, vol.21
, pp. 614-622
-
-
Wolf, N.S.1
Kone, A.2
Priestley, G.V.3
Bartelmez, S.H.4
-
10
-
-
0031435428
-
Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species
-
Goodell MA, Rosenzweig M, Kim H, et al. Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nature Med 1997; 3: 1337-1345.
-
(1997)
Nature Med
, vol.3
, pp. 1337-1345
-
-
Goodell, M.A.1
Rosenzweig, M.2
Kim, H.3
-
11
-
-
0037079708
-
The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors
-
Scharenberg CW, Harkey MA, Torok-Storb B. The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors. Blood 2002; 99: 507-512.
-
(2002)
Blood
, vol.99
, pp. 507-512
-
-
Scharenberg, C.W.1
Harkey, M.A.2
Torok-Storb, B.3
-
12
-
-
0036154828
-
The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells
-
Kim M, Turnquist H, Jackson J, et al. The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells. Clin Cancer Res 2002; 8: 22-28.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 22-28
-
-
Kim, M.1
Turnquist, H.2
Jackson, J.3
-
13
-
-
0032188998
-
Transduction of murine bone marrow cells with an MDR1 vector enables ex vivo stem cell expansion, but these expanded grafts cause a myeloproliferative syndrome in transplanted mice
-
Bunting KD, Galipeau J, Topham D, Benaim E, Sorrentino BP. Transduction of murine bone marrow cells with an MDR1 vector enables ex vivo stem cell expansion, but these expanded grafts cause a myeloproliferative syndrome in transplanted mice. Blood 1998; 92: 2269-2279.
-
(1998)
Blood
, vol.92
, pp. 2269-2279
-
-
Bunting, K.D.1
Galipeau, J.2
Topham, D.3
Benaim, E.4
Sorrentino, B.P.5
-
14
-
-
0036324223
-
Liver and marrow of adult mdr-1a/1b(-/-) mice show normal generation, function, and multi-tissue trafficking of primitive hematopoietic cells
-
Uchida N, Leung FY, Eaves CJ. Liver and marrow of adult mdr-1a/1b(-/-) mice show normal generation, function, and multi-tissue trafficking of primitive hematopoietic cells. Exp Hematol 2002; 30: 862-869.
-
(2002)
Exp Hematol
, vol.30
, pp. 862-869
-
-
Uchida, N.1
Leung, F.Y.2
Eaves, C.J.3
-
15
-
-
0036646107
-
Transport of phosphatidylserine via P-glycoprotein in a human gastric carcinoma cell line
-
Pohl A, Lage H, Muller P, Pomorski T, Herrmann A. Transport of phosphatidylserine via P-glycoprotein in a human gastric carcinoma cell line. Biochem J 2002; 365: 259-268.
-
(2002)
Biochem J
, vol.365
, pp. 259-268
-
-
Pohl, A.1
Lage, H.2
Muller, P.3
Pomorski, T.4
Herrmann, A.5
-
16
-
-
0034192163
-
P-glycoprotein plays a drug-efflux-independent role in augmenting cell survival in acute myeloblastic leukemia and is associated with modulation of a sphingomyelin-ceramide apoptotic pathway
-
Pallis M, Russell N. P-glycoprotein plays a drug-efflux-independent role in augmenting cell survival in acute myeloblastic leukemia and is associated with modulation of a sphingomyelin-ceramide apoptotic pathway. Blood 2000; 95: 2897-2904.
-
(2000)
Blood
, vol.95
, pp. 2897-2904
-
-
Pallis, M.1
Russell, N.2
-
17
-
-
0032562990
-
Evidence for a role of the multidrug resistance protein (MRP) in the outward translocation of NBD-phospholipids in the erythrocyte membrane
-
Kamp D, Haest CW. Evidence for a role of the multidrug resistance protein (MRP) in the outward translocation of NBD-phospholipids in the erythrocyte membrane. Biochim Biophys Acta 1998; 1372: 91-101.
-
(1998)
Biochim Biophys Acta
, vol.1372
, pp. 91-101
-
-
Kamp, D.1
Haest, C.W.2
-
18
-
-
0037125973
-
Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo
-
Zhou S, Morris JJ, Barnes Y, Lan L, Schuetz JD, Sorrentino BP. Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo. Proc Natl Acad Sci USA 2002; 99: 12339-12344.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12339-12344
-
-
Zhou, S.1
Morris, J.J.2
Barnes, Y.3
Lan, L.4
Schuetz, J.D.5
Sorrentino, B.P.6
-
19
-
-
0000890967
-
Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C
-
Allen JD, van Loevezijn A, Lakhai JM, et al. Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C. Mol Cancer Ther 2002; 1: 417-425.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 417-425
-
-
Allen, J.D.1
Van Loevezijn, A.2
Lakhai, J.M.3
-
20
-
-
0037180446
-
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
-
Jonker JW, Buitelaar M, Wagenaar E, et al. The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria. Proc Natl Acad Sci USA 2002; 99: 15649-15654.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15649-15654
-
-
Jonker, J.W.1
Buitelaar, M.2
Wagenaar, E.3
-
21
-
-
0036598543
-
C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance
-
Imai Y, Nakane M, Kage K, et al. C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance. Mol Cancer Ther 2002; 1: 611-616.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 611-616
-
-
Imai, Y.1
Nakane, M.2
Kage, K.3
-
22
-
-
0036731995
-
MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients
-
Illmer T, Schuler US, Thiede C, et al. MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients. Cancer Res 2002; 62: 4955-4962.
-
(2002)
Cancer Res
, vol.62
, pp. 4955-4962
-
-
Illmer, T.1
Schuler, U.S.2
Thiede, C.3
-
23
-
-
0035987003
-
Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8
-
Iida A, Saito S, Sekine A, et al. Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8. J Hum Genet 2002; 47: 285-310.
-
(2002)
J Hum Genet
, vol.47
, pp. 285-310
-
-
Iida, A.1
Saito, S.2
Sekine, A.3
-
24
-
-
0037246432
-
Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestine
-
Zamber CP, Lamba JK, Yasuda K, et al. Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestine. Pharmacogenetics 2003; 13: 19-28.
-
(2003)
Pharmacogenetics
, vol.13
, pp. 19-28
-
-
Zamber, C.P.1
Lamba, J.K.2
Yasuda, K.3
-
25
-
-
0038311942
-
Single-Nucleotide Polymorphism (SNP) analysis in the ABC half-transporter ABCG2 (MXR/BCRP/ABCP1)
-
Honjo Y, Morisaki K, Huff LM, et al. Single-Nucleotide Polymorphism (SNP) analysis in the ABC half-transporter ABCG2 (MXR/BCRP/ABCP1). Cancer Biol Ther 2002; 1: 696-702.
-
(2002)
Cancer Biol Ther
, vol.1
, pp. 696-702
-
-
Honjo, Y.1
Morisaki, K.2
Huff, L.M.3
-
26
-
-
0035884595
-
Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells
-
Honjo Y, Hrycyna CA, Yan QW, et al. Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells. Cancer Res 2001; 61: 6635-6639.
-
(2001)
Cancer Res
, vol.61
, pp. 6635-6639
-
-
Honjo, Y.1
Hrycyna, C.A.2
Yan, Q.W.3
-
27
-
-
0037089528
-
A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for doxorubicin resistance
-
Allen JD, Jackson SC, Schinkel AH. A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for doxorubicin resistance. Cancer Res 2002; 62: 2294-2299.
-
(2002)
Cancer Res
, vol.62
, pp. 2294-2299
-
-
Allen, J.D.1
Jackson, S.C.2
Schinkel, A.H.3
-
28
-
-
0035883060
-
A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia
-
Wulf GG, Wang RY, Kuehnle I, et al. A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia. Blood 2001; 98: 1166-1173.
-
(2001)
Blood
, vol.98
, pp. 1166-1173
-
-
Wulf, G.G.1
Wang, R.Y.2
Kuehnle, I.3
-
29
-
-
0029008635
-
Lack of correlation between expression and function of P-glycoprotein in acute myeloid leukemia cell lines
-
Bailly JD, Muller C, Jaffrezou JP, et al. Lack of correlation between expression and function of P-glycoprotein in acute myeloid leukemia cell lines. Leukemia 1995; 9: 799-807.
-
(1995)
Leukemia
, vol.9
, pp. 799-807
-
-
Bailly, J.D.1
Muller, C.2
Jaffrezou, J.P.3
-
30
-
-
0037114644
-
Low levels of ABCG2 expression in adult AML blast samples
-
Abbott BL, Colapietro AM, Barnes Y, Marini F, Andreeff M, Sorrentino BP. Low levels of ABCG2 expression in adult AML blast samples. Blood 2002; 100: 4594-4601.
-
(2002)
Blood
, vol.100
, pp. 4594-4601
-
-
Abbott, B.L.1
Colapietro, A.M.2
Barnes, Y.3
Marini, F.4
Andreeff, M.5
Sorrentino, B.P.6
-
31
-
-
0037444271
-
Mouse breast cancer resistance protein (Bcrp1/Abcg2) mediates etoposide resistance and transport, but etoposide oral availability is limited primarily by P-glycoprotein
-
Allen JD, Van Dort SC, Buitelaar M, Van Tellingen O, Schinkel AH. Mouse breast cancer resistance protein (Bcrp1/Abcg2) mediates etoposide resistance and transport, but etoposide oral availability is limited primarily by P-glycoprotein. Cancer Res 2003; 63: 1339-1344.
-
(2003)
Cancer Res
, vol.63
, pp. 1339-1344
-
-
Allen, J.D.1
Van Dort, S.C.2
Buitelaar, M.3
Van Tellingen, O.4
Schinkel, A.H.5
-
32
-
-
0034817098
-
Breast cancer resistance protein directly confers SN-38 resistance of lung cancer cells
-
Kawabata S, Oka M, Shiozawa K, et al. Breast cancer resistance protein directly confers SN-38 resistance of lung cancer cells. Biochem Biophys Res Commun 2001; 280: 1216-1223.
-
(2001)
Biochem Biophys Res Commun
, vol.280
, pp. 1216-1223
-
-
Kawabata, S.1
Oka, M.2
Shiozawa, K.3
-
33
-
-
18544375425
-
Induction of breast cancer resistance protein by the camptothecin derivative DX-8951f is associated with minor reduction of antitumour activity
-
van Hattum AH, Hoogsteen IJ, Schluper HM, et al. Induction of breast cancer resistance protein by the camptothecin derivative DX-8951f is associated with minor reduction of antitumour activity. Br J Cancer 2002; 87: 665-672.
-
(2002)
Br J Cancer
, vol.87
, pp. 665-672
-
-
Van Hattum, A.H.1
Hoogsteen, I.J.2
Schluper, H.M.3
-
34
-
-
0036643756
-
Novel camptothecin derivative BNP1350 in experimental human ovarian cancer: Determination of efficacy and possible mechanisms of resistance
-
van Hattum AH, Schluper HM, Hausheer FH, Pinedo HM, Boven E. Novel camptothecin derivative BNP1350 in experimental human ovarian cancer: determination of efficacy and possible mechanisms of resistance. Int J Cancer 2002; 100: 22-29.
-
(2002)
Int J Cancer
, vol.100
, pp. 22-29
-
-
Van Hattum, A.H.1
Schluper, H.M.2
Hausheer, F.H.3
Pinedo, H.M.4
Boven, E.5
-
35
-
-
0035881280
-
A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line
-
Perego P, De Cesare M, De Isabella P, et al. A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line. Cancer Res 2001; 61: 6034-6037.
-
(2001)
Cancer Res
, vol.61
, pp. 6034-6037
-
-
Perego, P.1
De Cesare, M.2
De Isabella, P.3
-
36
-
-
0034906472
-
Circumvention of breast cancer resistance protein (BCRP)-mediated resistance to camptothecins in vitro using non-substrate drugs or the BCRP inhibitor GF120918
-
Maliepaard M, van Gastelen MA, Tohgo A, et al. Circumvention of breast cancer resistance protein (BCRP)-mediated resistance to camptothecins in vitro using non-substrate drugs or the BCRP inhibitor GF120918. Clin Cancer Res 2001; 7: 935-941.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 935-941
-
-
Maliepaard, M.1
Van Gastelen, M.A.2
Tohgo, A.3
-
38
-
-
0035300476
-
Identification of breast cancer resistant protein/mitoxantrone resistance/placenta-specific, ATP-binding cassette transporter as a transporter of NB-506 and J-107088, topoisomerase I inhibitors with an indolocarbazole structure
-
Komatani H, Kotani H, Hara Y, et al. Identification of breast cancer resistant protein/mitoxantrone resistance/ placenta-specific, ATP-binding cassette transporter as a transporter of NB-506 and J-107088, topoisomerase I inhibitors with an indolocarbazole structure. Cancer Res 2001; 61: 2827-2832.
-
(2001)
Cancer Res
, vol.61
, pp. 2827-2832
-
-
Komatani, H.1
Kotani, H.2
Hara, Y.3
-
39
-
-
18444411317
-
Reduced effect of gemtuzumab ozogamicin (CMA-676) on P-glyco-protein and/or CD34-positive leukemia cells and its restoration by multidrug resistance modifiers
-
Matsui H, Takeshita A, Naito K, et al. Reduced effect of gemtuzumab ozogamicin (CMA-676) on P-glyco-protein and/or CD34-positive leukemia cells and its restoration by multidrug resistance modifiers. Leukemia 2002; 16: 813-819.
-
(2002)
Leukemia
, vol.16
, pp. 813-819
-
-
Matsui, H.1
Takeshita, A.2
Naito, K.3
-
40
-
-
0033852105
-
Calicheamicin-conjugated humanized anti-CD33 monoclonal anti-body (gemtuzumab ozogamicin, CMA-676) shows cytocidal effect on CD33-positive leukemia cell lines, but is inactive on P-glycoprotein-expressing sublines
-
Naito K, Takeshita A, Shigeno K, et al. Calicheamicin-conjugated humanized anti-CD33 monoclonal anti-body (gemtuzumab ozogamicin, CMA-676) shows cytocidal effect on CD33-positive leukemia cell lines, but is inactive on P-glycoprotein-expressing sublines. Leukemia 2000; 14: 1436-1443.
-
(2000)
Leukemia
, vol.14
, pp. 1436-1443
-
-
Naito, K.1
Takeshita, A.2
Shigeno, K.3
-
41
-
-
0036733277
-
Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin)
-
Larson RA, Boogaerts M, Estey E, et al. Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin). Leukemia 2002; 16: 1627-1636.
-
(2002)
Leukemia
, vol.16
, pp. 1627-1636
-
-
Larson, R.A.1
Boogaerts, M.2
Estey, E.3
-
43
-
-
0029910797
-
Maternal exposure to potential inhibitors of DNA topoisomerase II and infant leukemia: A report from the Children's Cancer Group
-
Ross JA, Potter JD, Reaman GH, Pendergrass TW, Robison LL. Maternal exposure to potential inhibitors of DNA topoisomerase II and infant leukemia: a report from the Children's Cancer Group. Cancer Causes Control 1996; 7: 581-590
-
(1996)
Cancer Causes Control
, vol.7
, pp. 581-590
-
-
Ross, J.A.1
Potter, J.D.2
Reaman, G.H.3
Pendergrass, T.W.4
Robison, L.L.5
-
44
-
-
0034712748
-
Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia
-
Strick R, Strissel PL, Borgers S, Smith SL, Rowley JD. Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia. Proc Natl Acad Sci USA 2000; 97: 4790-4795.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 4790-4795
-
-
Strick, R.1
Strissel, P.L.2
Borgers, S.3
Smith, S.L.4
Rowley, J.D.5
-
45
-
-
0035138482
-
Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells
-
Robey RW, Medina-Perez WY, Nishiyama K, et al. Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells. Clin Cancer Res 2001; 7: 145-152.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 145-152
-
-
Robey, R.W.1
Medina-Perez, W.Y.2
Nishiyama, K.3
-
46
-
-
0037280015
-
Molecular modes of action of cephalotaxine and homoharringtonine from the coniferous tree Cephalotaxus hainanensis in human tumor cell lines
-
Efferth T, Sauerbrey A, Halatsch ME, Ross DD, Gebhart E. Molecular modes of action of cephalotaxine and homoharringtonine from the coniferous tree Cephalotaxus hainanensis in human tumor cell lines. Naunyn Schmiedebergs Arch Pharmacol 2003; 367: 56-67.
-
(2003)
Naunyn Schmiedebergs Arch Pharmacol
, vol.367
, pp. 56-67
-
-
Efferth, T.1
Sauerbrey, A.2
Halatsch, M.E.3
Ross, D.D.4
Gebhart, E.5
-
47
-
-
0037218382
-
Breast cancer resistance protein (BCRP/ABCG2) induces cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors
-
Wang X, Furukawa T, Nitanda T, et al. Breast cancer resistance protein (BCRP/ABCG2) induces cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors. Mol Pharmacol 2003; 63: 65-72.
-
(2003)
Mol Pharmacol
, vol.63
, pp. 65-72
-
-
Wang, X.1
Furukawa, T.2
Nitanda, T.3
-
48
-
-
0036732010
-
Overexpression of wild-type breast cancer resistance protein mediates methotrexate resistance
-
Volk EL, Farley KM, Wu Y, Li F, Robey RW, Schneider E. Overexpression of wild-type breast cancer resistance protein mediates methotrexate resistance. Cancer Res 2002; 62: 5035-5040.
-
(2002)
Cancer Res
, vol.62
, pp. 5035-5040
-
-
Volk, E.L.1
Farley, K.M.2
Wu, Y.3
Li, F.4
Robey, R.W.5
Schneider, E.6
-
49
-
-
0037438387
-
Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis
-
Akashi K, He X, Chen J, et al. Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis. Blood 2003; 101: 383-389.
-
(2003)
Blood
, vol.101
, pp. 383-389
-
-
Akashi, K.1
He, X.2
Chen, J.3
-
51
-
-
0034194009
-
Isolation and characterization of human CD34- Lin- and CD34+ Lin- hematopoietic stem cells using cell surface markers AC133 and CD7
-
Gallacher L, Murdoch B, Wu DM, Karanu FN, Keeney M, Bhatia M. Isolation and characterization of human CD34- Lin- and CD34+ Lin- hematopoietic stem cells using cell surface markers AC133 and CD7. Blood 2000, 95: 2813-2820.
-
(2000)
Blood
, vol.95
, pp. 2813-2820
-
-
Gallacher, L.1
Murdoch, B.2
Wu, D.M.3
Karanu, F.N.4
Keeney, M.5
Bhatia, M.6
-
52
-
-
0037305235
-
Identification of a novel class of human adherent CD34- stem cells that give rise to SCID-repopulating cells
-
Kuci S, Wessels JT, Buhring HJ, et al. Identification of a novel class of human adherent CD34- stem cells that give rise to SCID-repopulating cells. Blood 2003; 101: 869-876.
-
(2003)
Blood
, vol.101
, pp. 869-876
-
-
Kuci, S.1
Wessels, J.T.2
Buhring, H.J.3
-
53
-
-
0033529756
-
Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity
-
Storms RW, Trujillo AP, Springer JB, et al. Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity. Proc Natl Acad Sci USA 1999; 96: 9118-9123.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 9118-9123
-
-
Storms, R.W.1
Trujillo, A.P.2
Springer, J.B.3
-
54
-
-
0034665902
-
Hoechst dye efflux reveals a novel CD7+ CD34- lymphoid progenitor in human umbilical cord blood
-
Storms RW, Goodell MA, Fisher A, Mulligan RC, Smith C. Hoechst dye efflux reveals a novel CD7+ CD34- lymphoid progenitor in human umbilical cord blood. Blood 2000; 96: 2125-2133.
-
(2000)
Blood
, vol.96
, pp. 2125-2133
-
-
Storms, R.W.1
Goodell, M.A.2
Fisher, A.3
Mulligan, R.C.4
Smith, C.5
-
55
-
-
0035877996
-
Identification of a novel, human multilymphoid progenitor in cord blood
-
Hao GL, Zhu J, Price MA, Payne KJ, Barsky LW, Crooks GM. Identification of a novel, human multilymphoid progenitor in cord blood. Blood 2001; 97: 3683-3690.
-
(2001)
Blood
, vol.97
, pp. 3683-3690
-
-
Hao, G.L.1
Zhu, J.2
Price, M.A.3
Payne, K.J.4
Barsky, L.W.5
Crooks, G.M.6
-
56
-
-
0035870289
-
Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues
-
Maliepaard M, Scheffer GL, Faneyte IF, et al. Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues. Cancer Res 2001; 61: 3458-3464.
-
(2001)
Cancer Res
, vol.61
, pp. 3458-3464
-
-
Maliepaard, M.1
Scheffer, G.L.2
Faneyte, I.F.3
-
57
-
-
0036297914
-
Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter
-
Lechner A, Leech CA, Abraham EJ, Nolan AL, Habener JF. Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter. Biochem Biophys Res Commun 2002; 293: 670-674.
-
(2002)
Biochem Biophys Res Commun
, vol.293
, pp. 670-674
-
-
Lechner, A.1
Leech, C.A.2
Abraham, E.J.3
Nolan, A.L.4
Habener, J.F.5
-
58
-
-
0037071546
-
Identification of myogenic-endothelial progenitor cells in the interstitial spaces of skeletal muscle
-
Tamaki T, Akatsuka A, Ando K, et al. Identification of myogenic-endothelial progenitor cells in the interstitial spaces of skeletal muscle. J Cell Biol 2002; 157: 571-577.
-
(2002)
J Cell Biol
, vol.157
, pp. 571-577
-
-
Tamaki, T.1
Akatsuka, A.2
Ando, K.3
-
59
-
-
0029096486
-
Correlation of multidrug resistance (MDR1) protein expression with functional dye/drug efflux in acute myeloid leukemia by multiparameter flow cytometry: Identification of discordant MDR-/efflux+ and MDR1+/efflux-cases
-
Leith CP, Chen IM, Kopecky KJ, et al. Correlation of multidrug resistance (MDR1) protein expression with functional dye/drug efflux in acute myeloid leukemia by multiparameter flow cytometry: identification of discordant MDR-/efflux+ and MDR1+/efflux- cases. Blood 1995; 86: 2329-2342.
-
(1995)
Blood
, vol.86
, pp. 2329-2342
-
-
Leith, C.P.1
Chen, I.M.2
Kopecky, K.J.3
-
60
-
-
0035877989
-
Hoechst 33342 efflux identifies a subpopulation of cytogenetically normal CD34(+)CD38(-) progenitor cells from patients with acute myeloid leukemia
-
Feuring-Buske M, Hogge DE. Hoechst 33342 efflux identifies a subpopulation of cytogenetically normal CD34(+)CD38(-) progenitor cells from patients with acute myeloid leukemia. Blood 2001; 97: 3882-3889.
-
(2001)
Blood
, vol.97
, pp. 3882-3889
-
-
Feuring-Buske, M.1
Hogge, D.E.2
-
61
-
-
0034234653
-
Expression of breast cancer resistance protein in blast cells from patients with acute leukemia
-
Ross DD, Karp JE, Chen TT, Doyle LA. Expression of breast cancer resistance protein in blast cells from patients with acute leukemia. Blood 2000; 96: 365-368.
-
(2000)
Blood
, vol.96
, pp. 365-368
-
-
Ross, D.D.1
Karp, J.E.2
Chen, T.T.3
Doyle, L.A.4
-
62
-
-
0035726216
-
Breast cancer resistance protein expression and resistance to daunorubicin in blast cells from patients with acute myeloid leukaemia
-
Sargent JM, Williamson CJ, Maliepaard M, Elgie AW, Scheper RJ, Taylor CG. Breast cancer resistance protein expression and resistance to daunorubicin in blast cells from patients with acute myeloid leukaemia. Br J Haematol 2001; 115: 257-262.
-
(2001)
Br J Haematol
, vol.115
, pp. 257-262
-
-
Sargent, J.M.1
Williamson, C.J.2
Maliepaard, M.3
Elgie, A.W.4
Scheper, R.J.5
Taylor, C.G.6
-
63
-
-
0036100195
-
Increased expression of the breast cancer resistance protein (BCRP) in relapsed or refractory acute myeloid leukemia (AML)
-
van den Heuvel-Eibrink MM, Wiemer EA, Prins A, et al. Increased expression of the breast cancer resistance protein (BCRP) in relapsed or refractory acute myeloid leukemia (AML). Leukemia 2002; 16: 833-839.
-
(2002)
Leukemia
, vol.16
, pp. 833-839
-
-
Van den Heuvel-Eibrink, M.M.1
Wiemer, E.A.2
Prins, A.3
-
64
-
-
0036052296
-
BCRP gene expression is associated with a poor response to remission induction therapy in childhood acute myeloid leukemia
-
Steinbach D, Sell W, Voigt A, Hermann J, Zintl F, Sauerbrey A. BCRP gene expression is associated with a poor response to remission induction therapy in childhood acute myeloid leukemia. Leukemia 2002; 16: 1443-1447.
-
(2002)
Leukemia
, vol.16
, pp. 1443-1447
-
-
Steinbach, D.1
Sell, W.2
Voigt, A.3
Hermann, J.4
Zintl, F.5
Sauerbrey, A.6
-
65
-
-
0037093101
-
Expression and activity of breast cancer resistance protein (BCRP) in de novo and relapsed acute myeloid leukemia
-
van der Kolk DM, Vellenga E, Scheffer GL, et al. Expression and activity of breast cancer resistance protein (BCRP) in de novo and relapsed acute myeloid leukemia. Blood 2002; 99: 3763-3770.
-
(2002)
Blood
, vol.99
, pp. 3763-3770
-
-
Van der Kolk, D.M.1
Vellenga, E.2
Scheffer, G.L.3
-
66
-
-
0037872761
-
Function of the ABC transporters, P-glycoprotein, multi-drug resistance protein and breast cancer resistance protein, in minimal residual disease in acute myeloid leukemia
-
Van Der Pol MA, Broxterman HJ, Pater JM, et al. Function of the ABC transporters, P-glycoprotein, multi-drug resistance protein and breast cancer resistance protein, in minimal residual disease in acute myeloid leukemia. Haematologica 2003; 88: 134-147.
-
(2003)
Haematologica
, vol.88
, pp. 134-147
-
-
Van Der Pol, M.A.1
Broxterman, H.J.2
Pater, J.M.3
-
67
-
-
0005040904
-
A systematic collaborative overview of randomized trials comparing idarubicin with daunorubicin (or other anthracyclines) as induction therapy for acute myeloid leukaemia
-
AML Collaborative Group
-
Wheatley K. A systematic collaborative overview of randomized trials comparing idarubicin with daunorubicin (or other anthracyclines) as induction therapy for acute myeloid leukaemia. AML Collaborative Group. Br J Haematol 1998; 103: 100-109.
-
(1998)
Br J Haematol
, vol.103
, pp. 100-109
-
-
Wheatley, K.1
-
68
-
-
0036064629
-
Expression of the BCRP gene (ABCG2/MXR/ABCP) in childhood acute lymphoblastic leukaemia
-
Sauerbrey A, Sell W, Steinbach D, Voigt A, Zintl F. Expression of the BCRP gene (ABCG2/MXR/ABCP) in childhood acute lymphoblastic leukaemia. Br J Haematol 2002; 118: 147-150.
-
(2002)
Br J Haematol
, vol.118
, pp. 147-150
-
-
Sauerbrey, A.1
Sell, W.2
Steinbach, D.3
Voigt, A.4
Zintl, F.5
-
69
-
-
0037443754
-
MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models
-
Mahon FX, Belloc F, Lagarde V, et al. MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models. Blood 2003; 101: 2368-2373.
-
(2003)
Blood
, vol.101
, pp. 2368-2373
-
-
Mahon, F.X.1
Belloc, F.2
Lagarde, V.3
-
70
-
-
0345144023
-
High levels of BAX, low levels of MRP-1, and high platelets are independent predictors of response to imatinib in myeloid blast crisis of CML
-
Lange T, Gunther C, Kohler T, et al. High levels of BAX, low levels of MRP-1, and high platelets are independent predictors of response to imatinib in myeloid blast crisis of CML. Blood 2003; 101: 2152-2155.
-
(2003)
Blood
, vol.101
, pp. 2152-2155
-
-
Lange, T.1
Gunther, C.2
Kohler, T.3
-
71
-
-
0034786310
-
Cells from chronic myelogenous leukaemia patients at presentation exhibit multidrug resistance not mediated by either MDR1 or MRP1
-
Carter A, Dann EJ, Katz T, et al. Cells from chronic myelogenous leukaemia patients at presentation exhibit multidrug resistance not mediated by either MDR1 or MRP1. Br J Haematol 2001; 114: 581-590.
-
(2001)
Br J Haematol
, vol.114
, pp. 581-590
-
-
Carter, A.1
Dann, E.J.2
Katz, T.3
-
72
-
-
24244476379
-
Expression of ABC family transporters: Breast cancer resistance protein (ABCG2) and P-glycoprotein in patients with chronic lymphoctyic leukemia (CLL)
-
Jamroziak K, Smolewski P, Cebula B, et al. Expression of ABC family transporters: breast cancer resistance protein (ABCG2) and P-glycoprotein in patients with chronic lymphoctyic leukemia (CLL). Proc Annu Meet Am Assoc Cancer Res 2003; a593.
-
(2003)
Proc Annu Meet Am Assoc Cancer Res
-
-
Jamroziak, K.1
Smolewski, P.2
Cebula, B.3
-
73
-
-
0037314795
-
RNA expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: Correlation with chemotherapeutic response
-
Burger H, Foekens JA, Look MP, et al. RNA expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: correlation with chemotherapeutic response. Clin Cancer Res 2003; 9: 827-836.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 827-836
-
-
Burger, H.1
Foekens, J.A.2
Look, M.P.3
-
74
-
-
0036554732
-
Expression of the breast cancer resistance protein in breast cancer
-
Faneyte IF, Kristel PM, Maliepaard M, et al. Expression of the breast cancer resistance protein in breast cancer. Clin Cancer Res 2002; 8: 1068-1074.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1068-1074
-
-
Faneyte, I.F.1
Kristel, P.M.2
Maliepaard, M.3
-
75
-
-
0037464302
-
Lung resistance-related protein as a predictor of clinical outcome in advanced testicular germ-cell tumours
-
Zurita AJ, Diestra JE, Condom E, et al. Lung resistance-related protein as a predictor of clinical outcome in advanced testicular germ-cell tumours. Br J Cancer 2003; 88: 879-886.
-
(2003)
Br J Cancer
, vol.88
, pp. 879-886
-
-
Zurita, A.J.1
Diestra, J.E.2
Condom, E.3
-
76
-
-
0036772386
-
Frequent expression of the multi-drug resistance-associated protein BCRP/MXR/ABCP/ABCG2 in human tumours detected by the BXP-21 monoclonal antibody in paraffin-embedded material
-
Diestra JE, Scheffer GL, Catala I, et al. Frequent expression of the multi-drug resistance-associated protein BCRP/MXR/ABCP/ABCG2 in human tumours detected by the BXP-21 monoclonal antibody in paraffin-embedded material. J Pathol 2002; 198: 213-219.
-
(2002)
J Pathol
, vol.198
, pp. 213-219
-
-
Diestra, J.E.1
Scheffer, G.L.2
Catala, I.3
-
77
-
-
0034789387
-
Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells
-
Ozvegy C, Litman T, Szakacs G, et al. Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells. Biochem Biophys Res Commun 2001; 285: 111-117.
-
(2001)
Biochem Biophys Res Commun
, vol.285
, pp. 111-117
-
-
Ozvegy, C.1
Litman, T.2
Szakacs, G.3
-
78
-
-
0035863314
-
The HER tyrosine kinase inhibitor CI1033 enhances cytotoxicity of 7-ethyl-10-hydroxycamptothecin and topotecan by inhibiting breast cancer resistance protein-mediated drug efflux
-
Erlichman C, Boerner SA, Hallgren CG, et al. The HER tyrosine kinase inhibitor CI1033 enhances cytotoxicity of 7-ethyl-10-hydroxycamptothecin and topotecan by inhibiting breast cancer resistance protein-mediated drug efflux. Cancer Res 2001; 61: 739-748.
-
(2001)
Cancer Res
, vol.61
, pp. 739-748
-
-
Erlichman, C.1
Boerner, S.A.2
Hallgren, C.G.3
-
79
-
-
24244467699
-
Gefitinib ('Iressa', ZD1839) inhibits topotecan efflux in small cell lung cancer cells overexpressing breast cancer resistance protein (BCRP/ABCG2)
-
Nakamura Y, Oka M, Shiozowa K, et al. Gefitinib ('Iressa', ZD1839) inhibits topotecan efflux in small cell lung cancer cells overexpressing breast cancer resistance protein (BCRP/ABCG2). Proc Annu Meet Am Assoc Cancer Res 2003; a4679.
-
(2003)
Proc Annu Meet Am Assoc Cancer Res
-
-
Nakamura, Y.1
Oka, M.2
Shiozowa, K.3
-
80
-
-
0142153372
-
Imatinib mesylate (STI571, Gleevec) is a potent inhibitor of BCRP(ABCG2) and reverses topotecan resistance in vitro
-
Houghton PJ, Germain GS, Schuetz JD, Stewart CF, Buchdunger E, Traxler R. Imatinib mesylate (STI571, Gleevec) is a potent inhibitor of BCRP(ABCG2) and reverses topotecan resistance in vitro. Proc Am Assoc Cancer Res 2003; a1959.
-
(2003)
Proc Am Assoc Cancer Res
-
-
Houghton, P.J.1
Germain, G.S.2
Schuetz, J.D.3
Stewart, C.F.4
Buchdunger, E.5
Traxler, R.6
-
81
-
-
0032535004
-
Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C
-
Rabindran SK, He H, Singh M, et al. Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C. Cancer Res 1998; 58: 5850-5858.
-
(1998)
Cancer Res
, vol.58
, pp. 5850-5858
-
-
Rabindran, S.K.1
He, H.2
Singh, M.3
-
82
-
-
0033966957
-
Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein
-
Rabindran SK, Ross DD, Doyle LA, Yang W, Greenberger LM. Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res 2000; 60: 47-50.
-
(2000)
Cancer Res
, vol.60
, pp. 47-50
-
-
Rabindran, S.K.1
Ross, D.D.2
Doyle, L.A.3
Yang, W.4
Greenberger, L.M.5
-
83
-
-
0035049256
-
Selection and characterization of a high-activity ribozyme directed against the antineoplastic drug resistance-associated ABC transporter BCRP/MXR/ABCG2
-
Kowalski P, Wichert A, Holm PS, Dietel M, Lage H. Selection and characterization of a high-activity ribozyme directed against the antineoplastic drug resistance-associated ABC transporter BCRP/MXR/ABCG2. Cancer Gene Ther 2001; 8: 185-192.
-
(2001)
Cancer Gene Ther
, vol.8
, pp. 185-192
-
-
Kowalski, P.1
Wichert, A.2
Holm, P.S.3
Dietel, M.4
Lage, H.5
|