Staphylococcus aureus α-toxin-induced cell death: Predominant necrosis despite apoptotic caspase activation

Cell Death and Differentiation

Volumn 10, Issue 11, 2003, Pages 1260-1272

  Essmann, F ^a   Bantel, H ^a,c   Totzke, G ^a   Engels, I H ^a,d   Sinha, B ^b   Schulze Osthoff, K ^a   Janicke R U ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

toxin; Bcl 2; Caspase independent death; DNA fragmentation; Necrosis; zVAD fmk

Indexed keywords

ADENOSINE TRIPHOSPHATE; APOPTOSIS INDUCING FACTOR; CASPASE; CELL DNA; DNA FRAGMENT; FAS ANTIGEN; LACTATE DEHYDROGENASE; PROPIDIUM IODIDE; PROTEIN BCL 2; STAPHYLOCOCCUS ALPHA TOXIN;

APOPTOSIS; ARTICLE; BREAST CARCINOMA; CANCER CELL; CANCER CELL CULTURE; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL STRUCTURE; CELL SWELLING; CELL VACUOLE; CONTROLLED STUDY; CYTOPLASM; ELECTRON MICROSCOPY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN DEPLETION; STAPHYLOCOCCUS AUREUS;

AMINO ACID CHLOROMETHYL KETONES; ANTIBODIES; ANTIGENS, CD95; BACTERIAL TOXINS; CASPASES; CELL DEATH; CELL LINE, TUMOR; DNA FRAGMENTATION; ENZYME ACTIVATION; ENZYME INHIBITORS; HEMOLYSIN PROTEINS; HUMANS; JURKAT CELLS; MICROSCOPY, ELECTRON; MODELS, BIOLOGICAL; MOLECULAR WEIGHT; NECROSIS; PROTO-ONCOGENE PROTEINS C-BCL-2; STAPHYLOCOCCUS AUREUS;

MINK CELL FOCUS-FORMING VIRUS; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 0141809842     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401301     Document Type: Article

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