Internalization of Staphylococcus aureus by endothelial cells induces apoptosis

Infection and Immunity

Volumn 66, Issue 12, 1998, Pages 5994-5998

  Menzies, Barbara E ^a,b,c   Kourteva, Iordanka ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHALASIN D; DNA FRAGMENT; LYSOSTAPHIN;

APOPTOSIS; ARTICLE; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; CELL INVASION; CELL NUCLEUS; CYTOPLASM; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; TRANSMISSION ELECTRON MICROSCOPY; UMBILICAL VEIN;

EID: 0031741285     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.12.5994-5998.1998     Document Type: Article

References (19)

1. Baran, J., K. Guzik, W. Hryniewicz, M. Ernst, H. D. Flad, and J. Pryjma. 1996. Apoptosis of monocytes and prolonged survival of granulocytes as a result of phagocytosis of bacteria. Infect. Immun. 64:4242-4248.
2. Bayles, K. W., C. A. Wesson, L. E. Liou, L. K. Fox, G. A. Bohach, and W. R. Trumble. 1998. Intracellular Staphylococcus aureus escapes the endosome and induces apoptosis in epithelial cells. Infect. Immun. 66:336-342.
3. Beekhuizen, H., J. S. van de Gevel, B. Olsson, I. J. van Benten, and R. van Furth. 1997. Infection of human vascular endothelial cells with Staphylococcus aureus induces hyperadhesiveness for human monocytes and granulocytes. J. Immun. 158:774-782.
4. Cheung, A. L., J. M. Koomey, C. A. Butler, S. J. Projan, and V. A. Fischetti. 1992. Regulation of expoprotein expression in Staphylococcus aureus by a locus (sar) distinct from agr. Proc. Natl. Acad. Sci. USA 89:6462-6466.
5. Drake, T. A., and M. Pang. 1988. Staphylococcus aureus induces tissue factor expression in cultured human cardiac valve endothelium. J. Infect. Dis. 157:749-756.
6. Hamill, R. J., J. M. Vann, and R. A. Proctor. 1986. Phagocytosis of Staphylococcus aureus by cultured bovine endothelial cells: model for postadherence events in endovascular infections. Infect. Immun. 54:833-836.
7. Ing, M. B., L. M. Baddour, and A. S. Bayer. 1997. Bacteremia and infective endocarditis: pathogenesis, diagnosis, and complications, p. 331-353. In K. B. Crossley and G. L. Archer (ed.), The staphylococci. Churchill Livingstone, New York, N.Y.
8. Jonas, D., I. Walev, T. Berger, M. Liebetrau, M. Palmer, and S. Bhakdi. 1994. Novel path to apoptosis: small transmembrane pores created by staphylococcal alpha-toxin in T lymphocytes evoke internucleosomal DNA degradation. Infect. Immun. 62:1304-1312.
9. Kernodle, D. S., R. K. R. Voladri, B. E. Menzies, C. C. Hager, and K. M. Edwards. 1997. Expression of an antisense hla fragment in Staphylococcus aureus reduces alpha-toxin production in vitro and attenuates lethal activity in a murine model. Infect. Immun. 65:179-184.
10. Lowy, F. D., J. Fant, L. L. Higgins, S. K. Ogawa, and V. B. Hatcher. 1988. Staphylococcus aureus-human endothelial cell interactions. J. Ultrastruct. Mol. Struct. Res. 98:137-146.
11. Novick, R. P. 1991. Genetic systems in staphylococci. Methods Enzymol. 204:587-636.
12. Ogawa, S. K., E. R. Yurberg, V. B. Hatcher, M. A. Levitt, and F. D. Lowy. 1985. Bacterial adherence to human endothelial cells in vitro. Infect. Immun. 50:218-224.
13. Sheagren, J. N. 1984. S. aureus: the persistent pathogen. N. Engl. J. Med. 310:1368-1373, 1437-1442.
14. Vann, J. M., and R. A. Proctor. 1988. Cytotoxic effects of ingested Staphylococcus aureus on bovine endothelial cells: role of S. aureus α-hemolysin. Microb. Pathog. 4:443-453.
15. Vesga, O., M. C. Groeschel, M. F. Otten, D. W. Brar, J. M. Vann, and R. A. Proctor. 1996. Staphylococcus aureus small colony variants are induced by the endothelial cell intracellular milieu. J. Infect. Dis. 173:739-742.
16. Watankunakorn, C., and T. Burkert. 1993. Infective endocarditis at a large community teaching hospital, 1980-1990. A review of 210 episodes. Medicine (Baltimore) 72:90-102.
17. Weinstein, L., and J. J. Schlesinger. 1974. Pathoanatomic, pathophysiologic, and clinical correlation in endocarditis. N. Engl. J. Med. 291:832-837, 1122-1126.
18. Yao, L., V. Bengualid, F. D. Lowy, J. J. Gibbons, V. B. Hatcher, and J. W. Berman. 1995. Internalization of Staphylococcus aureus by endothelial cells induces cytokine gene expression. Infect. Immun. 63:1835-1839.
19. Zychlinshy, A., and P. Sansonetti. 1997. Apoptosis in bacterial pathogenesis. J. Clin. Invest. 100:493-496.