Reactive oxygen species generation is independent of de novo sphingolipids in apoptotic photosensitized cells

Experimental Cell Research

Volumn 288, Issue 2, 2003, Pages 425-436

  Dolgachev, Vladislav ^a   Nagy, Biserka ^b   Taffe, Bonita ^a   Hanada, Kentaro ^c   Separovic, Duska ^a  

^a WAYNE STATE UNIVERSITY   (United States)

^b UNIVERSITY OF ZAGREB   (Croatia)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

Apoptosis; MnTBAP; Oxidative stress; Pc4; Photodynamic therapy; Sphingolipids; Superoxide; m

Indexed keywords

CERAMIDE; ENZYME; MANGANESE DERIVATIVE; MANGANESE TETRAKIS(4 BENZOIC ACID)PORPHYRIN; PHTHALOCYANINE; REACTIVE OXYGEN METABOLITE; SERINE PALMITOYLTRANSFERASE; SPHINGANINE; SPHINGOLIPID; THERMOZYMOCIDIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROTECTION; CHO CELL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LIPOGENESIS; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; PRIORITY JOURNAL;

EID: 0043065270     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4827(03)00235-0     Document Type: Article

References (59)

1. Quillet-Mary A., Jaffrezou J.-P., Mansat V., Bordier C., Naval J., Laurent G. Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis. J. Biol. Chem. 272:1997;21388-21395.
2. Hildeman D.A., Mitchell T., Teague T.K., Henson P., Day B.J., Kappler J., Marrack P.C. Reactive oxygen species regulate activation-induced T cell apoptosis. Immunity. 10:1999;735-744.
3. Du J., Suzuki H., Nagase F., Akhand A.A., Ma X.Y., Yokoyama T., Miyata T., Nakashima I. Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis process. Free Radic. Biol. Med. 31:2001;469-478.
4. Cohen G.M. Caspases the executioners of apoptosis . Biochem. J. 326:1997;1-16.
5. Green D.R., Reed J.C. Mitochondria and apoptosis. Science. 281:1998;1309-1312.
6. Debatin K.M., Poncet D., Kroemer G. Chemotherapy targeting the mitochondrial cell death pathway . Oncogene. 21:2002;8786-8803.
7. Garzotto M., White-Jones M., Jiang Y., Ehleiter D., Liao W.C., Haimovitz-Friedman A., Fuks Z., Kolesnick R. 12-O-Tetradecanoylphorbol-13-acetate-induced apoptosis in LNCaP cells is mediated through ceramide synthase. Cancer Res. 58:1998;2260-2264.
8. Perry D.K., Carton J., Shah A.K., Meredith F., Uhlinger D.J., Hannun Y.A. Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis. J. Biol. Chem. 275:2000;9078-9084.
9. Wang H., Giuliano A.E., Cabot M.C. Enhanced de novo ceramide generation through activation of serine palmitoyltransferase by the P-glycoprotein antagonist SDZ PSC 833 in breast cancer cells. Mol. Cancer Ther. 1:2002;719-726.
10. Hanada K., Hara T., Nishijima M., Kuge O., Dickson R.C., Nagiec M.M. A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis. J. Biol. Chem. 272:1997;32108-32114.
11. Weiss B., Stoffel W. Human and murine serine-palmitoyl-CoA transferase - cloning, expression and characterization of the key enzyme in sphingolipid synthesis. Eur. J. Biochem. 249:1997;239-247.
12. Schmelz E.M., Dombrink-Kurtzman M.A., Roberts P.C., Kozutsumi Y., Kawasaki T., Merrill A.H. Jr. Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. Toxicol. Appl. Pharmacol. 148:1998;252-260.
13. Tolleson W.H., Couch L.H., Melchior W.B. Jr., Jenkins G.R., Muskhelishvili M., Muskhelishvili L., McGarrity L.J., Domon O., Morris S.M., Howard P.C. Fumonisin B1 induces apoptosis in cultured human keratinocytes through sphinganine accumulation and ceramide depletion. Int. J. Oncol. 14:1999;833-843.
14. Zamzami N., Marchetti P., Castedo M., Decaudin D., Macho A., Hirsch T., Susin S.A., Petit P.X., Mignotte B., Kroemer G. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J. Exp. Med. 182:1995;367-377.
15. Garcia-Ruiz C., Colell A., Mari M., Morales A., Fernandez-Checa J.C. Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. J. Cell Biochem. 272:1997;11369-11377.
16. Arora A.S., Jones B.J., Patel T.C., Bronk S.F., Gores G.J. Ceramide induces hepatocyte cell death through disruption of mitochondrial function in the rat. Hepatology. 25:1997;958-963.
17. Kroesen B.J., Pettus B., Luberto C., Busman M., Sietsma H., de Leij L., Hannun Y.A. Induction of apoptosis through B-cell receptor cross-linking occurs via de novo generated C16-ceramide and involves mitochondria. J. Biol. Chem. 276:2001;13606-13614.
18. Whitacre C.M., Feyes D.K., Satoh T., Grossmann J., Mulvihill J.W., Mukhtar H., Oleinick N.L. Photodynamic therapy with the phthalocyanine photosensitizer Pc 4 of SW480 human colon cancer xenografts in athymic mice. Clin. Cancer Res. 6:2000;2021-2027.
19. Dougherty T.J., Gomer C.J., Henderson B.W., Jori G., Kessel D., Korbelik M., Moan J., Peng Q. Photodynamic therapy review . J. Natl. Cancer Inst. 90:1998;889-902.
20. •OH by irradiation of the photosensitizer zinc(II) phthalocyanine. J. Photochem. Photobiol. B. 38:1997;196-202.
21. Golab J., Nowis D., Skrzycki M., Czeczot H., Baranczyk-Kuzma A., Wilczynski G.M., Makowski M., Mroz P., Kozar K., Kaminski R., Jalili A., Kopec M., Grzela T., Jakobisiak M. Antitumor effects of photodynamic therapy are potentiated by 2-methoxyestradiol. A superoxide dismutase inhibitor. J. Biol. Chem. 278:2003;407-414.
22. Lam M., Oleinick N.L., Nieminen A.L. Photodynamic therapy-induced apoptosis in epidermoid carcinoma cells. Reactive oxygen species and mitochondrial inner membrane permeabilization. J. Biol. Chem. 276:2001;47379-47386.
23. Vantieghem A., Xu Y., Declercq W., Vandenabeele P., Denecker G., Vandenheede J.R., Merlevede W., de Witte P.A., Agostinis P. Different pathways mediate cytochrome c release after photodynamic therapy with hypericin. Photochem. Photobiol. 74:2001;133-142.
24. Madesh M., Hajnoczky G. VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release. J Cell Biol. 155:2001;1003-1015.
25. Belzacq A.S., Jacotot E., Vieira H.L., Mistro D., Granville D.J., Xie Z., Reed J.C., Kroemer G., Brenner C. Apoptosis induction by the photosensitizer verteporfin identification of mitochondrial adenine nucleotide translocator as a critical target . Cancer Res. 61:2001;1260-1264.
26. Separovic D., He J., Oleinick N.L. Ceramide generation in response to photodynamic treatment of L5178Y mouse lymphoma cells. Cancer Res. 57:1997;1717-1721.
27. Separovic D., Mann K.J., Oleinick N.L. Association of ceramide accumulation with photodynamic treatment-induced cell death. Photochem. Photobiol. 68:1998;101-109.
28. Wispriyono B., Schmelz E., Pelayo H., Hanada K., Separovic D. A role for the de novo sphingolipids in apoptosis of photosensitized cells. Exp. Cell Res. 279:2002;153-165.
29. Gouaze V., Mirault M.E., Carpentier S., Salvayre R., Levade T., Andrieu-Abadie N. Glutathione peroxidase-1 overexpression prevents ceramide production and partially inhibits apoptosis in doxorubicin-treated human breast carcinoma cells. Mol. Pharmacol. 60:2001;488-496.
30. Datta K., Biswal S.S., Kehrer J.P. The 5-lipoxygenase-activating protein (FLAP) inhibitor, MK886, induces apoptosis independently of FLAP. Biochem. J. 340:(Pt. 2):1999;371-375.
31. Maurer B.J., Metelitsa L.S., Seeger R.C., Cabot M.C., Reynolds C.P. Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)-retinamide in neuroblastoma cell lines. J. Natl. Cancer Inst. 91:1999;1138-1146.
32. Reers M., Smiley S.T., Mottola-Hartshorn C., Chen A., Lin M., Chen L.B. Mitochondrial membrane potential monitored by JC-1 dye. Methods Enzymol. 260:1995;406-417.
33. Zamzami N., Marchetti P., Castedo M., Zanin C., Vayssiere J.L., Petit P.X., Kroemer G. Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J. Exp. Med. 181:1995;1661-1672.
34. Castedo M., Ferri K., Roumier T., Metivier D., Zamzami N., Kroemer G. Quantitation of mitochondrial alterations associated with apoptosis. J. Immunol. Methods. 265:2002;39-47.
35. Salvioli S., Ardizzoni A., Franceschi C., Cossarizza A. JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells implications for studies on mitochondrial functionality during apoptosis . FEBS Lett. 411:1997;77-82.
36. Santana P., Pena L.A., Haimovitz-Friedman A., Martin S., Green D., McLoughlin M., Cordon-Cardo C., Schuchman E.H., Fuks Z., Kolesnick R. Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis. Cell. 86:1996;189-199.
37. Varnes M.E., Chiu S.M., Xue L.Y., Oleinick N.L. Photodynamic therapy-induced apoptosis in lymphoma cells translocation of cytochrome c causes inhibition of respiration as well as caspase activation . Biochem. Biophys. Res. Commun. 255:1999;673-679.
38. Chiu S.M., Oleinick N.L. Dissociation of mitochondrial depolarization from cytochrome c release during apoptosis induced by photodynamic therapy. Br. J. Cancer. 84:2001;1099-1106.
39. Hanada K., Hara T., Fukasawa M., Yamaji A., Umeda M., Nishijima M. Mammalian cell mutants resistant to a sphingomyelin-directed cytolysin. Genetic and biochemical evidence for complex formation of the LCB1 protein with the LCB2 protein for serine palmitoyltransferase. J. Biol. Chem. 273:1998;33787-33794.
40. Li H., Junk P., Huwiler A., Burkhardt C., Wallerath T., Pfeilschifter J., Forstermann U. Dual effect of ceramide on human endothelial cells induction of oxidative stress and transcriptional upregulation of endothelial nitric oxide synthase . Circulation. 106:2002;2250-2256.
41. Phillips D.C., Allen K., Griffiths H.R. Synthetic ceramides induce growth arrest or apoptosis by altering cellular redox status. Arch. Biochem. Biophys. 407:2002;15-24.
42. Irie F., Hirabayashi Y. Ceramide prevents motoneuronal cell death through inhibition of oxidative signal. Neurosci. Res. 35:1999;135-144.
43. Listenberger L.L., Ory D.S., Schaffer J.E. Palmitate-induced apoptosis can occur through a ceramide-independent pathway. J. Biol. Chem. 276:2001;14890-14895.
44. Cabrero A., Alegret M., Sanchez R.M., Adzet T., Laguna J.C., Carrera M.V. Increased reactive oxygen species production down-regulates peroxisome proliferator-activated alpha pathway in C2C12 skeletal muscle cells. J. Biol. Chem. 277:2002;10100-10107.
45. Kolesnick R.N., Kronke M. Regulation of ceramide production and apoptosis. Annu. Rev. Physiol. 60:1998;643-665.
46. Ghafourifar P., Klein S.D., Schucht O., Schenk U., Pruschy M., Rocha S., Richter C. Ceramide induces cytochrome c release from isolated mitochondria. Importance of mitochondrial redox state. J. Biol. Chem. 274:1999;6080-6084.
47. Vance J.E. Phospholipid synthesis in a membrane fraction associated with mitochondria. J. Biol. Chem. 265:1990;7248-7256.
48. Scaffidi C., Fulda S., Srinivasan A., Friesen C., Li F., Tomaselli K.J., Debatin K.M., Krammer P.H., Peter M.E. Two CD95 (APO-1/Fas) signaling pathways. EMBO J. 17:1998;1675-1687.
49. Ruiz-Ruiz C., Lopez-Rivas A. Mitochondria-dependent and -independent mechanisms in tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis are both regulated by interferon-gamma in human breast tumour cells. Biochem. J. 365:2002;825-832.
50. Hannun Y.A., Luberto C., Argraves K.M. Enzymes of sphingolipid metabolism from modular to integrative signaling . Biochemistry. 40:2001;4893-4903.
51. Farrell A.M., Uchida Y., Nagiec M.M., Harris I.R., Dickson R.C., Elias P.M., Holleran W.M. UVB irradiation up-regulates serine palmitoyltransferase in cultured human keratinocytes. J. Lipid Res. 39:1998;2031-2038.
52. Moan J., Berg K. The photodegradation of porphyrins in cells can be used to estimate the lifetime of singlet oxygen. Photochem. Photobiol. 53:1991;549-553.
53. Oleinick N.L., Evans H.H. The photobiology of photodynamic therapy cellular targets and mechanisms . Radiat. Res. 150:1998;S146-156.
54. Taguchi H., Ogura Y., Takanashi T., Hashizoe M., Honda Y. In vivo quantitation of peroxides in the vitreous humor by fluorophotometry. Invest. Ophthalmol. Vis. Sci. 37:1996;1444-1450.
55. Faulkner K.M., Liochev S.I., Fridovich I. Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo. J. Biol. Chem. 269:1994;23471-23476.
56. Day B.J., Shawen S., Liochev S.I., Crapo J.D. A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced endothelial cell injury, in vitro. J. Pharmacol. Exp. Ther. 275:1995;1227-1232.
57. Day B.J., Fridovich I., Crapo J.D. Manganic porphyrins possess catalase activity and protect endothelial cells against hydrogen peroxide-mediated injury. Arch. Biochem. Biophys. 347:1997;256-262.
58. Zingarelli B., Day B.J., Crapo J.D., Salzman A.L., Szabo C. The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock. Br. J. Pharmacol. 120:1997;259-267.
59. Vergun O., Sobolevsky A.I., Yelshansky M.V., Keelan J., Khodorov B.I., Duchen M.R. Exploration of the role of reactive oxygen species in glutamate neurotoxicity in rat hippocampal neurones in culture. J. Physiol. 531:2001;147-163.