Fumonisin B1 induces apoptosis in cultured human keratinocytes through sphinganine accumulation and ceramide depletion

International Journal of Oncology

Volumn 14, Issue 5, 1999, Pages 833-843

  Tolleson, William H ^a   Couch, Letha H ^a   Melchior Jr , William B ^a   Jenkins, G Ronald ^a   Muskhelishvili, Marina ^a   Muskhelishvili, Levan ^a   McGarrity, Lynda J ^a   Domon, Olen ^a   Morris, Suzanne M ^a   Howard, Paul C ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Apoptosis; Ceramide; Fumonisin B1; Sphinganine; Sphingolipids

Indexed keywords

3 CHLOROALANINE; 3-CHLOROALANINE; BETA ALANINE; CARBOXYLIC ACID; CERAMIDE; DNA FRAGMENT; DRUG DERIVATIVE; ENZYME INHIBITOR; FUMONISIN; FUMONISIN B1; N ACETYLSPHINGOSINE; N-ACETYLSPHINGOSINE; SAFINGOL; SPHINGOLIPID; SPHINGOSINE; TERATOGENIC AGENT;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL SURVIVAL; CLONOGENIC ASSAY; CYTOLOGY; DRUG EFFECT; DRUG INTERACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; KERATINOCYTE; METABOLISM;

APOPTOSIS; BETA-ALANINE; CARBOXYLIC ACIDS; CELL SURVIVAL; CELLS, CULTURED; CERAMIDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLONY-FORMING UNITS ASSAY; DNA FRAGMENTATION; DRUG INTERACTIONS; ENZYME INHIBITORS; FUMONISINS; HUMANS; KERATINOCYTES; SPHINGOLIPIDS; SPHINGOSINE; TERATOGENS;

EID: 17944388410     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.14.5.833     Document Type: Article

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