Ceramide generation in response to photodynamic treatment of L5178Y mouse lymphoma cells

Cancer Research

Volumn 57, Issue 9, 1997, Pages 1717-1721

  Separovic, Duska ^a   He, Jin ^a   Oleinick, Nancy L ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; PHOTOSENSITIZING AGENT; PHTHALOCYANINE DERIVATIVE; SPHINGOSINE DERIVATIVE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; LYMPHOMA CELL; MOUSE; NONHUMAN; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; SECOND MESSENGER;

ANIMALS; APOPTOSIS; CERAMIDES; DNA FRAGMENTATION; LEUKEMIA L5178; MICE; PHOTOCHEMOTHERAPY; SPHINGOSINE; TIME FACTORS;

EID: 0030948694     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Henderson, B. W., and Dougherty, T. J. How does photodynamic therapy work? Photochem. Photobiol., 55: 145-157, 1992.
2. Agarwal, M. L., Clay, M. E., Harvey, E. J., Evans, H. H., Antunez, A. R., and Oleinick, N. L. Photodynamic therapy induces rapid cell death by apoptosis in L5178Y mouse lymphoma cells. Cancer Res., 51: 5993-5996, 1991.
3. He, X. Y., Sikes, R. A., Thomsen, S., Chung, L. W. K., and Jacques, S. L. Photodynamic thorapy with Photofrin II induces programmed cell death in carcinoma cell lines. Photochem. Photobiol., 59: 468-473, 1994.
4. Luo, Y., Chang, C. K., and Kessel, D. Rapid initiation of apoptosis by photodynamic therapy. Photochem. Photobiol., 63: 528-534, 1996.
5. Zaidi, S. I. A., Oleinick, N. L., Zaim, M. T., and Mukhtar, H. Apoptosis during photodynamic therapy-induced ablation of RIF-1 tumors in C3H mice: electron microscopic, histopathologic, and biochemical evidence. Photochem. Photobiol., 58: 771-776, 1993.
6. Agarwal, R., Korman, N. J., Mohan, R. R., Feyes, D. K., Jawed, S., Zaim, M. T., and Mukhtar, H. Apoptosis is an early event during phthalocyanine photodynamic therapy-induced ablation of chemically induced squamous papillomas in mouse skin. Photochem. Photobiol., 63: 547-552, 1996.
7. Zhou, C., Shunji, C., Jinsheng, D., Junlin, L., Jori, G., and Milanesi, C. Apoptosis of mouse MS-2 fibrosarcoma cells induced by photodynamic therapy with Zn(II)-phthalocyanine. J. Photochem. Photobiol. B Biol., 33: 219-223, 1996.
8. He, J., and Oleinick, N. L. Cell death mechanisms vary with photodynamic therapy dose and photosensitizer. SPIE, 2371: 92-96, 1995.
9. Agarwal, M. L., Larkin, H. E., Zaidi, S. I. A., Mukhtar, H., and Oleinick, N. L. Phospholipase activation triggers apoptosis in photosensitized mouse lymphoma cells. Cancer Res., 53: 5897-5902, 1993.
10. Haimovitz-Friedman, A., Kan, C-C., Ehleiter, D., Persaud, R. S., McLoughlin, M., Fuks, Z., and Kolesnick, R. N. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J. Exp. Med., 180: 525-535, 1994.
11. Santana, P., Pena, L. A., Haimovitz-Friedman, A., Martin, S., Green, D., McLoughlin, M., Cordon-Cardo, C., Schuchman, E. H., Fuks, Z., and Kolesnick, R. N. Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis. Cell, 86: 189-199, 1996.
12. Verheij, M., Bose, R., Lin, X. H., Yao, B., Jarvis, W. D., Grant, S., Birrer, M. J., Szabo, E., Zon, L. I., Kyriakis, J. M., Haimovitz-Friedman, A., Fuks, Z., and Kolesnick, R. N. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature (Lond.), 380: 75-79, 1996.
13. Tao, J-s., Sanghera, J. S., Pelech, S. L., Wong, G., and Levy, J. G. Stimulation of stress-activated protein kinase and p38 HOG1 kinase in murine keratinocytes following photodynamic therapy with benzoporphyrin derivative. J. Biol. Chem., 271: 27107-27115, 1996.
14. Oleinick, N. L., Antunez, A. R., Clay, M. E., Rihter, B. D., and Kenney, M. E. New phthalocyanine photosensitizers for photodynamic therapy. Photochem. Photobiol., 57: 242-247, 1993.
15. Ramakrishnan, N., Oleinick, N. L., Clay, M. E., Horng, M-F., Antunez, A. R., and Evans, H. H. DNA lesions and DNA degradation in mouse lymphoma L5178Y cells after photodynamic treatment sensitized by chloroaluminum phthalocyanine. Photochem. Photobiol., 50: 373-378, 1989.
16. Preiss, J., Loomis, C. R., Bishop, W. R., Stein, R., Niedel, J. E., and Bell, R. M. Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras-and sis-transformed normal rat kidney cells. J. Biol. Chem., 261: 8597-8600, 1986.
17. 1-imidazoline receptors to diacylglyceride accumulation in PC12 rat pheochromocytoma cells. Mol. Pharmacol., 49: 668-675, 1996.
18. Li, X., Traganos, F., Melamed, M. R., and Darzynkiewicz, Z. Single-step procedure for labeling DNA strand breaks with fluorescein-or BODIPY-conjugated deoxynucleotides: detection of apoptosis and bromodeoxyuridine incorporation. Cytometry, 20: 172-180, 1995.
19. He, J., Agarwal, M. L., Larkin, H. E., Friedman, L. R., Xue, L-y., and Oleinick, N. L. The induction of partial resistance to photodynamic therapy by the proto-oncogene BCL-2. Photochem. Photobiol., 64: 845-852, 1996.
20. Hannun, Y. A., and Obeid, L. M. Ceramide: an intracellular signal for apoptosis. Trends Biochem. Sci., 20: 73-77, 1995.
21. Bielawska, A., Crane, H. M., Liotta, D., Obeid, L. M., and Hannun, Y. A. Selectivity of ceramide-mediated biology. J. Biol. Chem., 268: 26226-26232, 1993.
22. Hannun, Y. A. Functions of ceramide in coordinating cellular responses to stress. Science (Washington DC), 274: 1855-1859, 1996.
23. Schwartzman, R. A., and Cidlowski, J. A. Apoptosis: the biochemistry and molecular biology of programmed cell death. Endocr. Rev., 14: 133-151, 1993.
24. Coroneos, E., Wang, Y., Panuska, J. R., Templeton, D. J., and Kester, M. Sphingolipid metabolites differentially regulate extracellular signal-regulated kinase and stress-activated protein kinase cascades. Brochem. J., 316: 13-17, 1996.
25. Canman, C. E., and Kastan, M. B. Three paths to stress relief. Nature (Lond.), 384: 213-214, 1996.
26. Dobrowsky, R. T., Kamibayushi, C., Mumby, M. C., and Hannun, Y. A. Ceramide activates heterotrimeric protein phosphatase 2A. J. Biol. Chem., 268: 15523-15530, 1993.
27. Joseph, C. K., Byun, H-S., Bittman, R., and Kolesnick, R. N. Substrate recognition by ceramide-activated protein kinase. J. Biol. Chem., 268: 20002-20006, 1993.
28. Chmura, S. J., Nodzenski, E., Weichselbaum, R. R., and Quintans, J. Protein kinase C inhibition induces apoptosis and ceramide production through activation of a neutral sphingomyelinase. Cancer Res., 56: 2711-2714, 1996.
29. Bose, R., Verheij, M., Haimovitz-Friedman, A., Scotto, K., Fuks, Z., and Kolesnick, R. N. Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals. Cell, 82: 405-414, 1995.
30. Kolesnick, R. N. Sphingomyelin and derivatives as cellular signals. Prog. Lipid Res., 30: 1-38, 1991.