Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis

Journal of Biological Chemistry

Volumn 275, Issue 12, 2000, Pages 9078-9084

  Perry, David K ^a   Carton, Jill ^b   Shah, Amit K ^a   Meredith, Filmore ^c   Uhlinger, David J ^b   Hannun, Yusuf A ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b R W JOHNSON PHARMACEUTICAL RES I   (United States)

^c RUSSELL RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CERAMIDE; ETOPOSIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SERINE ACETYLTRANSFERASE; SPHINGOLIPID; SPHINGOMYELIN PHOSPHODIESTERASE;

APOPTOSIS; ARTICLE; BIOACCUMULATION; CHEMICAL REACTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEGRADATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MEMBRANE STABILIZATION; METABOLISM; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REACTION ANALYSIS; SYNTHESIS;

EID: 0034708594     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.12.9078     Document Type: Article

References (39)

1. Bose, R., Verheij, M., Haimovitz-Friedman, A., Scotto, K., Fuks, Z., and Kolesnick, R. (1995) Cell 82, 405-414
2. Paumen, M. B., Ishida, Y., Muramatsu, M., Yamamoto, M., and Honjo, T. (1997) J. Biol. Chem. 272, 3324-3329
3. Suzuki, A., Iwasaki, M., Kato, M., and Wagai, N. (1997) Exp. Cell Res. 233, 41-47
4. Shimabukuro, M., Zhou, Y.-T., Levi, M., and Unger, R. H. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 2498-2502
5. Garzotto, M., White-Jones, M., Jiang, Y., Ehleiter, D., Liao, W.-C., Haimovitz-Friedman, A., Fuks, Z., and Kolesnick, R. (1998) Cancer Res. 58, 2260-2264
6. Xu, J., Yeh, C.-H., Chen, S., He, L., Sensi, S. L., Canzoniero, L. M. T., Choi, D. W., and Hsu, C. Y. (1998) J. Biol. Chem. 273, 16521-16526
7. Cabot, M. C., Han, T.-Y., and Giuliano, A. E. (1998) FEBS Lett. 431, 185-188
8. Garzotta, M., Haimovitz-Friedman, A., Liao, W.-C., White-Jones, M., Huryk, R., Heston, W. D. W., Cardon-Cardo, C., Kolesnick, R., and Fuks, Z. (1999) Cancer Res. 59, 5194-5201
9. Wang, E., Norred, W. P., Bacon, C. W., Riley, R. T., and Merrill, A. H., Jr. (1991) J. Biol. Chem. 266, 14486-14490
10. Bielawska, A., Szulc, Z., and Hannun, Y. A. (2000) Methods Enzymol. 311, 518-535
11. Van Veldhoven, P. P., Bishop, W. R., Yurivich, D. A., and Bell, R. M. (1995) Biochem. Mol. Biol. Int. 36, 21-30
12. Bligh, E. G., and Dyer, W. J. (1959) Can. J. Biochem. Physiol. 37, 911-917
13. Williams, R. D., Wang, E., and Merrill, A. H., Jr. (1984) Arch. Biochem. Biophys. 228, 282-291
14. Perry, D. K., Smyth, M. J., Stennicke, H. R., Salvesen, G. S., Duriez, P., Poirier, G. G., and Hannun, Y. A. (1997) J. Biol. Chem. 272, 18530-18533
15. Chen, G. L., Yang, L., Rowe, T. C., Halligan, B. D., Tewey, K. M., and Liu, L. F. (1984) J. Biol. Chem. 259, 13560-13566
16. Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T., Jones, D. P., and Wang, X. (1997) Science 275, 1129-1132
17. Kaufmann, S. H., Desnoyers, S., Ottaviano, Y., Davidson, N. E., and Poirier, G. G. (1993) Cancer Res. 53, 3976-3985
18. Kaufmann, S. H. (1989) Cancer Res. 49, 5870-5878
19. Kaufmann, S. H. (1998) Biochim. Biophys. Acta 1400, 195-211
20. Zhang, P., Liu, B., Kang, S. W., Seok, M., Rhee, S. G., and Obeid, L. M. (1997) J. Biol. Chem. 272, 30615-30618
21. Smyth, M. J., Perry, D. K., Zhang, J., Poirier, G. G., Hannun, Y. A., and Obeid, L. M. (1996) Biochem. J. 316, 25-28
22. Obeid, L. M., Linardic, C. M., Karolak, L. A., and Hannun, Y. A. (1993) Science 259, 1769-1771
23. Merrill, A. H., Jr., van Echten, G., Wang, E., and Sandhoff, K. (1993) J. Biol. Chem. 268, 27299-27306
24. Williams, R. D., Sgoutas, D. S., Zaatari, G. S., and Santoianni, R. A. (1987) J. Lipid Res. 28, 1478-1481
25. Farrell, A. M., Uchida, Y., Nagiec, M. M., Harris, I. R., Dickson, R. C., Elias, P. M., and Holleran, W. M. (1998) J. Lipid Res. 39, 2031-2038
26. Mizushima, N., Koike, R., Kohsaka, H., Kushi, Y., Handa, S., Yagita, H., and Miyasaka, N. (1996) FEBS Lett. 395, 267-271
27. Takahashi, A., Alnemri, E. S., Lazebnik, Y. A., Fernandes-Alnemri, T., Litwack, G., Moir, R. D., Goldman, R. D., Poirier, G. G., Kaufmann, S. H., and Earnshaw, W. C. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 8395-8400
28. Thornberry, N. A., Rano, T. A., Peterson, E. P., Rasper, D. M., Timkey, T., Garcia-Calvo, M., Houtzager, V. M., Nordstrom, P. A., Roy, S., Vaillancourt, J. P., Chapman, K. T., and Nicholson, D. W. (1997) J. Biol. Chem. 272, 17907-17911
29. Martins, L. M., Kottke, T., Mesner, P. W., Basi, G. S., Sinha, S., Frigon, N., Jr., Tatar, E., Tung, J. S., Bryant, K., Takahashi, A., Svingen, P. A., Madden, B. J., McCormick, D. J., Earnshaw, W. C., and Kaufmann, S. H. (1997) J. Biol. Chem. 272, 7421-7430
30. Dbaibo, G. S., Perry, D. K., Gamard, C. J., Platt, R., Poirier, G. G., Obeid, L. M., and Hannun, Y. A. (1997) J. Exp. Med. 185, 481-490
31. Buede, R., Rinker-Schaffer, C., Pinto, W. J., Lester, R. L., and Dickson, R. C. (1991) J. Bacteriol. 173, 4325-4332
32. Patton, J. L., Srinivasan, B., Dickson, R. C., and Lester, R. L. (1992) J. Bacteriol. 174, 7180-7184
33. Jenkins, G. M., Richards, A., Wahl, T., Mao, C., Obeid, L., and Hannun, Y. A. (1997) J. Biol. Chem. 272, 32566-32572
34. Mandon, E. C., van Echten, G., Birk, R., Schmidt, R. R., and Sandhoff, K. (1991) Eur. J. Biochem. 198, 667-674
35. Chigorno, V., Negroni, E., Nicolini, M., and Sonnino, S. (1997) J. Lipid Res. 38, 1163-1169
36. Mandon, E. C., Ehses, I., Rother, J., van Echten, G., and Sandhoff, K. (1992) J. Biol. Chem. 267, 11144-11148
37. Futerman, A. H., Stieger, B., Hubbard, A. L., and Pagano, R. E. (1990) J. Biol. Chem. 265, 8650-8657
38. Jeckel, D., Karrenbauer, A., Burger, K. N. J., van Meer, G., and Wieland, F. (1992) J. Cell Biol. 117, 259-267
39. Linardic, C. M., and Hannun, Y. A. (1994) J. Biol. Chem. 269, 23530-23537