-
1
-
-
0029145379
-
Evidence for a critical telomere length in senescent human fibroblasts
-
Allsopp, R.C. and Harley, C.B. (1995) Evidence for a critical telomere length in senescent human fibroblasts. Exp. Cell Res., 219, 130-136.
-
(1995)
Exp. Cell Res.
, vol.219
, pp. 130-136
-
-
Allsopp, R.C.1
Harley, C.B.2
-
2
-
-
0029156035
-
Telomere shortening is associated with cell division in vitro and in vivo
-
Allsopp, R.C., Chang, E., Kashefi-Aazam, M., Rogaev, E.I., Piatyszek, M.A., Shay, J.W. and Harley, C.B. (1995) Telomere shortening is associated with cell division in vitro and in vivo. Exp. Cell Res., 220, 194-200.
-
(1995)
Exp. Cell Res.
, vol.220
, pp. 194-200
-
-
Allsopp, R.C.1
Chang, E.2
Kashefi-Aazam, M.3
Rogaev, E.I.4
Piatyszek, M.A.5
Shay, J.W.6
Harley, C.B.7
-
3
-
-
0032525092
-
Progressive telomere shortening in aplastic anemia
-
Ball, S.E., Gibson, F.M., Rizzo, S., Tooze, J.A., Marsh, J.C. and Gordon-Smith, E.C. (1998) Progressive telomere shortening in aplastic anemia. Blood, 91, 3582-3592.
-
(1998)
Blood
, vol.91
, pp. 3582-3592
-
-
Ball, S.E.1
Gibson, F.M.2
Rizzo, S.3
Tooze, J.A.4
Marsh, J.C.5
Gordon-Smith, E.C.6
-
4
-
-
0025731583
-
Structure and function of telomeres
-
Blackburn, E.H. (1991) Structure and function of telomeres. Nature, 350, 569-573.
-
(1991)
Nature
, vol.350
, pp. 569-573
-
-
Blackburn, E.H.1
-
5
-
-
0030931491
-
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
-
Blasco, M.A., Lee, H.W., Hande, M.P., Samper, E., Lansdorp, P.M., DePinho, R.A. and Greider, C.W. (1997) Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell, 91, 25-34.
-
(1997)
Cell
, vol.91
, pp. 25-34
-
-
Blasco, M.A.1
Lee, H.W.2
Hande, M.P.3
Samper, E.4
Lansdorp, P.M.5
DePinho, R.A.6
Greider, C.W.7
-
6
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
Bodnar, A.G. et al. (1998) Extension of life-span by introduction of telomerase into normal human cells, Science, 279, 349-352.
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
-
7
-
-
0029841549
-
Evidence that transcriptional activation by p53 plays a direct role in the induction of cellular senescence
-
Bond, J., Haughton, M., Blaydes, J., Gire, V., Wynford-Thomas, D. and Wyllie, F. (1996) Evidence that transcriptional activation by p53 plays a direct role in the induction of cellular senescence. Oncogene, 13, 2097-2104.
-
(1996)
Oncogene
, vol.13
, pp. 2097-2104
-
-
Bond, J.1
Haughton, M.2
Blaydes, J.3
Gire, V.4
Wynford-Thomas, D.5
Wyllie, F.6
-
8
-
-
0034235119
-
Telomere length shortening in chronic myelogenous leukemia is associated with reduced time to accelerated phase
-
Boultwood, J., Peniket, A., Watkins, F., Shepherd, P., McGale, P., Richards, S., Fidler, C., Littlewood, T.J. and Wainscoat J.S. (2000) Telomere length shortening in chronic myelogenous leukemia is associated with reduced time to accelerated phase, Blood, 96, 358-361.
-
(2000)
Blood
, vol.96
, pp. 358-361
-
-
Boultwood, J.1
Peniket, A.2
Watkins, F.3
Shepherd, P.4
McGale, P.5
Richards, S.6
Fidler, C.7
Littlewood, T.J.8
Wainscoat, J.S.9
-
9
-
-
0034028836
-
Tumor suppressors and oncogenes in cellular senescence
-
Bringold, F. and Serrano, M. (2000) Tumor suppressors and oncogenes in cellular senescence. Exp. Gerontol., 35, 317-329,
-
(2000)
Exp. Gerontol.
, vol.35
, pp. 317-329
-
-
Bringold, F.1
Serrano, M.2
-
10
-
-
0028856794
-
Telomere length and replicative aging in human vascular tissues
-
Chang, E. and Harley, C.B. (1995) Telomere length and replicative aging in human vascular tissues. Proc. Natl Acad. Sci. USA, 92, 11190-11194.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 11190-11194
-
-
Chang, E.1
Harley, C.B.2
-
11
-
-
0000748439
-
1/S boundary genes in human diploid fibroblasts during senescence
-
1/S boundary genes in human diploid fibroblasts during senescence. Front. Biosci., 2, 417-426.
-
(1997)
Front. Biosci.
, vol.2
, pp. 417-426
-
-
Chen, K.Y.1
-
12
-
-
0033553516
-
p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
-
Chin, L., Artandi, S.E., Shen, Q., Tam, A., Lee, S.L., Gottlieb, G.J., Greider, C.W. and DePinho, R.A. (1999) p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell, 97, 527-538.
-
(1999)
Cell
, vol.97
, pp. 527-538
-
-
Chin, L.1
Artandi, S.E.2
Shen, Q.3
Tam, A.4
Lee, S.L.5
Gottlieb, G.J.6
Greider, C.W.7
DePinho, R.A.8
-
13
-
-
0029846756
-
Liver failure and defective hepatocyte regeneration in interleukin-6 deficient mice
-
Cressman, D.E., Greenbaum, L.E., DeAngelis, R.A., Ciliberto, G., Furth, E.E., Poli, V. and Taub, R. (1996) Liver failure and defective hepatocyte regeneration in interleukin-6 deficient mice. Science, 274, 1379-1383.
-
(1996)
Science
, vol.274
, pp. 1379-1383
-
-
Cressman, D.E.1
Greenbaum, L.E.2
DeAngelis, R.A.3
Ciliberto, G.4
Furth, E.E.5
Poli, V.6
Taub, R.7
-
14
-
-
0022780338
-
A method for determining ploidy distributions in liver tissue by stereological analysis of nuclear size calibrated by flow cytometric DNA analysis
-
Danielsen, H., Lindmo, T. and Reith, A. (1986) A method for determining ploidy distributions in liver tissue by stereological analysis of nuclear size calibrated by flow cytometric DNA analysis. Cytometry, 7, 475-480.
-
(1986)
Cytometry
, vol.7
, pp. 475-480
-
-
Danielsen, H.1
Lindmo, T.2
Reith, A.3
-
15
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri, G.P. et al. (1995) A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl Acad. Sci. USA, 92, 9363-9367.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
-
16
-
-
0033816629
-
Uncoupling between phenotypic senescence and cell cycle arrest in aging p21-deficient fibroblasts
-
Dulic, V., Beney, G.E., Frebourg, G., Drullinger, L.F. and Stein, G.H. (2000) Uncoupling between phenotypic senescence and cell cycle arrest in aging p21-deficient fibroblasts. Mol. Cell. Biol., 20, 6741-6754.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 6741-6754
-
-
Dulic, V.1
Beney, G.E.2
Frebourg, G.3
Drullinger, L.F.4
Stein, G.H.5
-
17
-
-
0033973680
-
Telomeres and HIV disease
-
Effros, R.B. (2000) Telomeres and HIV disease. Microbes Infect., 2, 69-76.
-
(2000)
Microbes Infect.
, vol.2
, pp. 69-76
-
-
Effros, R.B.1
-
18
-
-
0034007745
-
Liver regeneration
-
Fausto, N. (2000) Liver regeneration. J. Hepatol., 32, 19-31.
-
(2000)
J. Hepatol.
, vol.32
, pp. 19-31
-
-
Fausto, N.1
-
19
-
-
0343228751
-
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis
-
Gonzalez-Suarez, E., Samper, E., Flores, J.M. and Blasco, M.A. (2000) Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis. Nat. Genet., 26, 114-117.
-
(2000)
Nat. Genet.
, vol.26
, pp. 114-117
-
-
Gonzalez-Suarez, E.1
Samper, E.2
Flores, J.M.3
Blasco, M.A.4
-
20
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley, C.B., Futcher, A.B. and Greider, C.W. (1990) Telomeres shorten during ageing of human fibroblasts. Nature, 345, 458-460.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
21
-
-
0035812845
-
The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
-
Hemann, M.T., Strong, M.A., Hao, L.Y. and Greider, C.W. (2001) The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell, 107, 67-77.
-
(2001)
Cell
, vol.107
, pp. 67-77
-
-
Hemann, M.T.1
Strong, M.A.2
Hao, L.Y.3
Greider, C.W.4
-
22
-
-
0033153424
-
Disease states associated with telomerase deficiency appear earlier in mice with short telomeres
-
Herrera, E., Samper, E., Martin-Caballero, J., Flores, J.M., Lee, H.W. and Blasco, M.A. (1999) Disease states associated with telomerase deficiency appear earlier in mice with short telomeres. EMBO J., 18, 2950-2960.
-
(1999)
EMBO J.
, vol.18
, pp. 2950-2960
-
-
Herrera, E.1
Samper, E.2
Martin-Caballero, J.3
Flores, J.M.4
Lee, H.W.5
Blasco, M.A.6
-
23
-
-
0001276586
-
Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal
-
Higgins, G.M. and Anderson, R.M. (1931) Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal. Arch. Pathol., 12, 186-202.
-
(1931)
Arch. Pathol.
, vol.12
, pp. 186-202
-
-
Higgins, G.M.1
Anderson, R.M.2
-
24
-
-
0033564106
-
p16/pRb pathway alterations are required for bypassing senescence in human prostate epithelial cells
-
Jarrard, D.R. et al. (1999) p16/pRb pathway alterations are required for bypassing senescence in human prostate epithelial cells. Cancer Res., 59, 2957-2964.
-
(1999)
Cancer Res.
, vol.59
, pp. 2957-2964
-
-
Jarrard, D.R.1
-
25
-
-
0031745857
-
Telomere shortening in the colonic mucosa of patients with ulcerative colitis
-
Kinouchi, Y., Hiwatashi, N., Chida, M., Nagashima, F., Takagi, S., Maekawa, H. and Toyota, T. (1998) Telomere shortening in the colonic mucosa of patients with ulcerative colitis. J. Gastroenterol., 33, 343-348.
-
(1998)
J. Gastroenterol.
, vol.33
, pp. 343-348
-
-
Kinouchi, Y.1
Hiwatashi, N.2
Chida, M.3
Nagashima, F.4
Takagi, S.5
Maekawa, H.6
Toyota, T.7
-
26
-
-
0029076880
-
Telomere shortening in chronic liver diseases
-
Kitada, T., Seki, S., Kawakita, N., Kuroki, T. and Monna, T. (1995) Telomere shortening in chronic liver diseases. Biochem. Biophys. Res. Commun., 211, 33-39.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.211
, pp. 33-39
-
-
Kitada, T.1
Seki, S.2
Kawakita, N.3
Kuroki, T.4
Monna, T.5
-
27
-
-
0035032741
-
Liver regeneration after hepatectomy
-
Kountouras, J., Boura, P., Lygidakis, N.J. (2001) Liver regeneration after hepatectomy. Hepatogastroenterology, 48, 556-562.
-
(2001)
Hepatogastroenterology
, vol.48
, pp. 556-562
-
-
Kountouras, J.1
Boura, P.2
Lygidakis, N.J.3
-
28
-
-
0032499210
-
Essential role of mouse telomerase in highly proliferative organs
-
Lee, H.W., Blasco, M.A., Gottlieb, G.J., Horner, J.W., 2nd, Greider, C.W. and DePinho, R.A. (1998) Essential role of mouse telomerase in highly proliferative organs. Nature, 392, 569-574.
-
(1998)
Nature
, vol.392
, pp. 569-574
-
-
Lee, H.W.1
Blasco, M.A.2
Gottlieb, G.J.3
Horner J.W. II4
Greider, C.W.5
DePinho, R.A.6
-
29
-
-
0034982905
-
Global changes in interleukin-6-dependent gene expression patterns in mouse livers after partial hepatectomy
-
Li, W., Liang, X., Leu, J.I., Kovalovich, K., Ciliberto, G. and Taub, R. (2001) Global changes in interleukin-6-dependent gene expression patterns in mouse livers after partial hepatectomy. Hepatology, 33, 1377-1386.
-
(2001)
Hepatology
, vol.33
, pp. 1377-1386
-
-
Li, W.1
Liang, X.2
Leu, J.I.3
Kovalovich, K.4
Ciliberto, G.5
Taub, R.6
-
30
-
-
0026043444
-
In vivo loss of telomeric repeats with age in humans
-
Lindsey, J., McGill, N.I., Lindsey, L.A., Green, DK. and Cooke, H.J. (1991) In vivo loss of telomeric repeats with age in humans. Mutat. Res., 256, 45-48.
-
(1991)
Mutat. Res.
, vol.256
, pp. 45-48
-
-
Lindsey, J.1
McGill, N.I.2
Lindsey, L.A.3
Green, D.K.4
Cooke, H.J.5
-
31
-
-
0028146852
-
1/S boundary may occur in human IMR-90 diploid fibroblasts during senescence
-
1/S boundary may occur in human IMR-90 diploid fibroblasts during senescence. J. Cell. Physiol., 160, 531-538.
-
(1994)
J. Cell. Physiol.
, vol.160
, pp. 531-538
-
-
Pang, J.H.1
Chen, K.Y.2
-
32
-
-
0035079864
-
Replicative senescence in normal liver, chronic hepatitis C and hepatocellular carcinomas
-
Paradis, V., Youssef, N., Dargere, D., Ba, N., Bonvoust, F., Deschatrette, J. and Bedossa, P. (2001) Replicative senescence in normal liver, chronic hepatitis C and hepatocellular carcinomas. Hum. Pathol., 32, 327-332.
-
(2001)
Hum. Pathol.
, vol.32
, pp. 327-332
-
-
Paradis, V.1
Youssef, N.2
Dargere, D.3
Ba, N.4
Bonvoust, F.5
Deschatrette, J.6
Bedossa, P.7
-
33
-
-
0009779607
-
-
Wiley, New York, NY
-
Poon, S.S. and Lansdorp, P.M. (2001) Current Protocols in Cell Biology. Wiley, New York, NY, pp. 18.4.1-18.4.21.
-
(2001)
Current Protocols in Cell Biology
, pp. 1841-18421
-
-
Poon, S.S.1
Lansdorp, P.M.2
-
34
-
-
0033525558
-
Longevity, stress response and cancer in aging telomerase deficient mice
-
Rudolph, K.L., Chang, S., Lee, H.-W., Blasco, M., Gottlieb, G.J., Greider, C. and DePinho, R.A. (1999) Longevity, stress response and cancer in aging telomerase deficient mice. Cell, 96, 701-712.
-
(1999)
Cell
, vol.96
, pp. 701-712
-
-
Rudolph, K.L.1
Chang, S.2
Lee, H.-W.3
Blasco, M.4
Gottlieb, G.J.5
Greider, C.6
DePinho, R.A.7
-
35
-
-
0034681457
-
Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery
-
Rudolph, K.L., Chang, S., Millard, M., Schreiber-Agus, N. and DePinho, R.A. (2000) Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery. Science, 287, 1253-1258.
-
(2000)
Science
, vol.287
, pp. 1253-1258
-
-
Rudolph, K.L.1
Chang, S.2
Millard, M.3
Schreiber-Agus, N.4
DePinho, R.A.5
-
37
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano, M., Lin, A.W., McCurrach, M.E., Beach, D. and Lowe, S.W. (1997) Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell, 88, 593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
38
-
-
0021738524
-
Flow cytometric analysis of mouse hepatocyte ploidy. II. The development of polyploidy pattern in four mice strains with different life spans
-
Severin, E., Willers, R. and Bettecken, T. (1984) Flow cytometric analysis of mouse hepatocyte ploidy. II. The development of polyploidy pattern in four mice strains with different life spans. Cell Tissue Res., 238, 649-652.
-
(1984)
Cell Tissue Res.
, vol.238
, pp. 649-652
-
-
Severin, E.1
Willers, R.2
Bettecken, T.3
-
39
-
-
0034713329
-
Is β-galactosidase staining a marker of senescence in vitro and in vivo?
-
Severino, J., Allen, R.G., Balin, S., Balin, A. and Cristofalo, V.J. (2000) Is β-galactosidase staining a marker of senescence in vitro and in vivo? Exp. Cell Res., 257, 162-171.
-
(2000)
Exp. Cell Res.
, vol.257
, pp. 162-171
-
-
Severino, J.1
Allen, R.G.2
Balin, S.3
Balin, A.4
Cristofalo, V.J.5
-
40
-
-
0026054961
-
A role for both RB and p53 in the regulation of human cellular senescence
-
Shay, J.W., Pereira-Smith, O.M. and Wright, W.E. (1991) A role for both RB and p53 in the regulation of human cellular senescence. Exp. Cell Res., 196, 33-39.
-
(1991)
Exp. Cell Res.
, vol.196
, pp. 33-39
-
-
Shay, J.W.1
Pereira-Smith, O.M.2
Wright, W.E.3
-
41
-
-
0037102234
-
Different telomere damage signaling pathways in human and mouse cells
-
Smogorzewska, A. and de Lange, T (2002) Different telomere damage signaling pathways in human and mouse cells. EMBO J., 21, 4338-4348.
-
(2002)
EMBO J.
, vol.21
, pp. 4338-4348
-
-
Smogorzewska, A.1
De Lange, T.2
-
43
-
-
0029924534
-
From telomere loss to p53 induction and activation of a DNA-damage pathway at senescence: The telomere loss/DNA damage model of cell aging
-
Vaziri, H. and Benchimol, S. (1996) From telomere loss to p53 induction and activation of a DNA-damage pathway at senescence: the telomere loss/DNA damage model of cell aging. Exp. Gerontol., 31, 295-301.
-
(1996)
Exp. Gerontol.
, vol.31
, pp. 295-301
-
-
Vaziri, H.1
Benchimol, S.2
-
44
-
-
0027486732
-
Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes
-
Vaziri, H., Schachter, F., Uchida, I., Wei, L., Zhu, X., Effros, R., Cohen, D. and Harley, C.B. (1993) Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am. J. Hum. Genet., 52, 661-667.
-
(1993)
Am. J. Hum. Genet.
, vol.52
, pp. 661-667
-
-
Vaziri, H.1
Schachter, F.2
Uchida, I.3
Wei, L.4
Zhu, X.5
Effros, R.6
Cohen, D.7
Harley, C.B.8
-
45
-
-
0028077099
-
Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age
-
Vaziri, H., Dragowska, W., Allsopp, R.C., Thomas, T.E., Harley, C.B. and Lansdorp, P.M. (1994) Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age. Proc. Natl Acad. Sci. USA, 91, 9857-9860.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9857-9860
-
-
Vaziri, H.1
Dragowska, W.2
Allsopp, R.C.3
Thomas, T.E.4
Harley, C.B.5
Lansdorp, P.M.6
-
46
-
-
0035960043
-
The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita
-
Vulliamy, T., Marrone, A., Goldman, F., Dearlove, A., Bessler, M., Mason, P.J. and Dokal, I. (2001) The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita. Nature, 413, 432-435.
-
(2001)
Nature
, vol.413
, pp. 432-435
-
-
Vulliamy, T.1
Marrone, A.2
Goldman, F.3
Dearlove, A.4
Bessler, M.5
Mason, P.J.6
Dokal, I.7
-
47
-
-
18444374159
-
Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis
-
Wiemann, S.U. et al. (2002) Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis. FASEB J., 16, 935-942.
-
(2002)
FASEB J.
, vol.16
, pp. 935-942
-
-
Wiemann, S.U.1
-
48
-
-
0026680249
-
The two-stage mechanism controlling cellular senescence and immortalization
-
Wright, W.E. and Shay, J.W. (1992) The two-stage mechanism controlling cellular senescence and immortalization. Exp. Gerontol., 27, 383-389.
-
(1992)
Exp. Gerontol.
, vol.27
, pp. 383-389
-
-
Wright, W.E.1
Shay, J.W.2
-
49
-
-
0025279059
-
In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs
-
Yu, G.L., Bradley, J.D., Attardi, L.D. and Blackburn, E.H. (1990) In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs. Nature, 344, 126-132.
-
(1990)
Nature
, vol.344
, pp. 126-132
-
-
Yu, G.L.1
Bradley, J.D.2
Attardi, L.D.3
Blackburn, E.H.4
|