Alternative binding modes of an inhibitor to two different kinases

European Journal of Biochemistry

Volumn 270, Issue 15, 2003, Pages 3174-3181

  De Moliner, Erika ^a,b   Brown, Nick R ^a   Johnson, Louise N ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

CK2; Cyclin dependent protein kinase 2; Protein kinase inhibitors; Tetrabromobenzotriazole

Indexed keywords

4,5,6,7 TETRABROMOBENZOTRIAZOLE; ADENOSINE TRIPHOSPHATE; BENZOTRIAZOLE DERIVATIVE; CASEIN KINASE II; CYCLIN A; CYCLIN DEPENDENT KINASE 2; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHORYLASE KINASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CRYSTAL STRUCTURE; DRUG TARGETING; ENZYME BINDING; HUMAN; IC 50; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN INTERACTION;

ADENOSINE TRIPHOSPHATE; BENZIMIDAZOLES; BINDING SITES; CASEIN KINASE II; CDC2-CDC28 KINASES; CYCLIN A; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASES; ENZYME INHIBITORS; HUMANS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES;

EUKARYOTA;

EID: 0042769409     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2003.03697.x     Document Type: Article

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