메뉴 건너뛰기




Volumn 3, Issue 5, 2003, Pages 829-841

Contraceptive vaccines

Author keywords

Contraception; Human chorionic gonadotropin; Oocytes; Spermatozoa; Zona pellucida

Indexed keywords

BACTERIAL PROTEIN; CHOLERA TOXIN B SUBUNIT; CHORIONIC GONADOTROPIN; CHORIONIC GONADOTROPIN ANTIBODY; CONTRACEPTIVE VACCINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DIPHTHERIA TETANUS TOXOID; ENTEROTOXIN; ENTEROTOXIN B; FERTILIN; FOLLITROPIN; GLYCOPROTEIN GP 120; GONADORELIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HUMAN IMMUNODEFICIENCY VIRUS 1 PROTEIN; HUMAN IMMUNOGLOBULIN; HYBRID PROTEIN; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 12; LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE ISOENZYME X; MALE CONTRACEPTIVE AGENT; PH 17 ANTIGEN; PH 20 ANTIGEN; PH 30 ANTIGEN; QS 21; SP56 ANTIGEN; SPERM ANTIGEN; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZONA PELLUCIDA PROTEIN;

EID: 0042671195     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/14712598.3.5.829     Document Type: Review
Times cited : (17)

References (113)
  • 1
    • 0033539392 scopus 로고    scopus 로고
    • Science, medicine, and the future. Contraception
    • BAIRD DT, GLASIER AF: Science, medicine, and the future. Contraception. Br. Med. J. (1999) 319:969-972.
    • (1999) Br. Med. J. , vol.319 , pp. 969-972
    • Baird, D.T.1    Glasier, A.F.2
  • 2
    • 0031713599 scopus 로고    scopus 로고
    • The immunology of reproduction: Update
    • GUPTA SK: The immunology of reproduction: update. Immunol. Today (1998) 19:433-434.
    • (1998) Immunol. Today , vol.19 , pp. 433-434
    • Gupta, S.K.1
  • 4
    • 0017693634 scopus 로고
    • Sperm/egg interaction: The specificity of human spermatozoa
    • BEDFORD JM: Sperm/egg interaction: the specificity of human spermatozoa. Anat Rec. (1977) 188:477-488.
    • (1977) Anat. Rec. , vol.188 , pp. 477-488
    • Bedford, J.M.1
  • 5
    • 0035162082 scopus 로고    scopus 로고
    • Antizona and antisperm antibodies in women with endometriosis and/or infertility
    • SZCZEPANSKA M, SKRZYPCZAK J, KAMIENICZNA M, KURPISZ M: Antizona and antisperm antibodies in women with endometriosis and/or infertility. Fertil. Steril. (2001) 75:97-105
    • (2001) Fertil. Steril. , vol.75 , pp. 97-105
    • Szczepanska, M.1    Skrzypczak, J.2    Kamieniczna, M.3    Kurpisz, M.4
  • 6
    • 0028205188 scopus 로고
    • Immunity to zona pellucida in women with low response to ovarian stimulation, in unexplained infertility and after multiple IVF attempts
    • HOVAV Y, ALMAGOR M, BENBENISHTI D, MARGALIOTH EJ, KAFKA I, YAFFE H: Immunity to zona pellucida in women with low response to ovarian stimulation, in unexplained infertility and after multiple IVF attempts. Hum. Reprod. (1994) 9:643-645.
    • (1994) Hum. Reprod. , vol.9 , pp. 643-645
    • Hovav, Y.1    Almagor, M.2    Benbenishti, D.3    Margalioth, E.J.4    Kafka, I.5    Yaffe, H.6
  • 7
    • 0023917933 scopus 로고
    • Zona pellucida glycoproteins
    • WASSARMAN PM: Zona pellucida glycoproteins. Ann. Rev. Biochem. (1988) 57:415-442.
    • (1988) Ann. Rev. Biochem. , vol.57 , pp. 415-442
    • Wassarman, P.M.1
  • 8
    • 0029818998 scopus 로고    scopus 로고
    • Mice homozygous for an insertional mutation in the Zp3 gene lack a zona pellucida and are infertile
    • RANKIN T, FAMILARI M, LEE E et al.: Mice homozygous for an insertional mutation in the Zp3 gene lack a zona pellucida and are infertile. Development (1996) 122:2903-2910.
    • (1996) Development , vol.122 , pp. 2903-2910
    • Rankin, T.1    Familari, M.2    Lee, E.3
  • 9
    • 0032821285 scopus 로고    scopus 로고
    • Abnormal zonae pellucidae in mice lacking ZP1 result in early embryonic loss
    • RANKIN T, TALBOT P, LEE E, DEAN J: Abnormal zonae pellucidae in mice lacking ZP1 result in early embryonic loss. Development (1999) 126:3847-3855.
    • (1999) Development , vol.126 , pp. 3847-3855
    • Rankin, T.1    Talbot, P.2    Lee, E.3    Dean, J.4
  • 10
    • 0035029161 scopus 로고    scopus 로고
    • Defective zonae pellucidae in Zp2-null mice disrupt folliculogenesis, fertility and development
    • RANKIN TL, O'BRIEN M, LEE E, WIGGLESWORTH K, EPPIG J, DEAN J: Defective zonae pellucidae in Zp2-null mice disrupt folliculogenesis, fertility and development. Development (2001) 128:1119-11126.
    • (2001) Development , vol.128 , pp. 1119-11126
    • Rankin, T.L.1    O'Brien, M.2    Lee, E.3    Wigglesworth, K.4    Eppig, J.5    Dean, J.6
  • 11
    • 0029892411 scopus 로고    scopus 로고
    • Evaluating zona pellucida structure and function using antibodies to rabbit 55 kDa ZP protein: Expressed in baculovirus expression system
    • PRASAD SV, WILKINS B, SKINNER SM, DUNBAR BS: Evaluating zona pellucida structure and function using antibodies to rabbit 55 kDa ZP protein: expressed in baculovirus expression system. Mol. Reprod. Dev. (1996) 43:519-529.
    • (1996) Mol. Reprod. Dev. , vol.43 , pp. 519-529
    • Prasad, S.V.1    Wilkins, B.2    Skinner, S.M.3    Dunbar, B.S.4
  • 12
    • 0035084331 scopus 로고    scopus 로고
    • Purified and refolded recombinant bonnet monkey (Macaca radiata) zona pellucida glycoprotein-B expressed in Escherichia coli binds to spermatozoa
    • GOVIND CK, GAHLAY GK, CHOUDHURY S, GUPTA SK: Purified and refolded recombinant bonnet monkey (Macaca radiata) zona pellucida glycoprotein-B expressed in Escherichia coli binds to spermatozoa. Biol. Reprod. (2001) 64:1147-1152.
    • (2001) Biol. Reprod. , vol.64 , pp. 1147-1152
    • Govind, C.K.1    Gahlay, G.K.2    Choudhury, S.3    Gupta, S.K.4
  • 14
    • 0031853969 scopus 로고    scopus 로고
    • Evaluation of the contraceptive potential of recombinant ZP3 and human ZP3 peptides in a primate model - Their safety and efficacy
    • PATERSON M, WILSON MR, MORRIS KD, VAN DUIN M, AITKEN RJ: Evaluation of the contraceptive potential of recombinant ZP3 and human ZP3 peptides in a primate model - their safety and efficacy. Am. J. Reprod. Immunol. (1998) 40:198-209.
    • (1998) Am. J. Reprod. Immunol. , vol.40 , pp. 198-209
    • Paterson, M.1    Wilson, M.R.2    Morris, K.D.3    Van Duin, M.4    Aitken, R.J.5
  • 15
    • 0023200953 scopus 로고
    • Polyclonal antibodies to a 32 kDa deglycosylated polypeptide from the porcine zona pellucida will prevent human gamete interaction in vitro
    • HENDERSON CJ, BRAUDE P, AITKEN RJ: Polyclonal antibodies to a 32 kDa deglycosylated polypeptide from the porcine zona pellucida will prevent human gamete interaction in vitro. Gamete Res. (1987) 18:251-265.
    • (1987) Gamete Res. , vol.18 , pp. 251-265
    • Henderson, C.J.1    Braude, P.2    Aitken, R.J.3
  • 16
    • 0023179594 scopus 로고
    • Analysis of the biological properties of antibodies raised against intact and deglycosylated porcine zonae pellucidae
    • HENDERSON CJ, HULME MJ, AITKEN RJ: Analysis of the biological properties of antibodies raised against intact and deglycosylated porcine zonae pellucidae. Gamete Res. (1987) 16:323-341.
    • (1987) Gamete Res. , vol.16 , pp. 323-341
    • Henderson, C.J.1    Hulme, M.J.2    Aitken, R.J.3
  • 17
    • 0036364516 scopus 로고    scopus 로고
    • Porcine zona pellucida (PZP) immunocontraception of wild horses (Equus caballus) in Nevada: A 10 year study
    • TURNER JW JR, LIU IK, FLANAGAN DR, BYNUM KS, RUTBERG AT: Porcine zona pellucida (PZP) immunocontraception of wild horses (Equus caballus) in Nevada: a 10 year study. Reproduction (2002) 60 (Suppl.):177-186. Recent example of contraceptive vaccines targeting the ZP finding application in the control of feral animal populations.
    • (2002) Reproduction , vol.60 , Issue.SUPPL. , pp. 177-186
    • Turner J.W., Jr.1    Liu, I.K.2    Flanagan, D.R.3    Bynum, K.S.4    Rutberg, A.T.5
  • 18
    • 0031973545 scopus 로고    scopus 로고
    • Infertility in mice induced by a recombinant ectromelia virus expressing mouse zona pellucida glycoprotein 3
    • JACKSON RJ, MAGUIRE DJ, HINDS LA, RAMSHAW IA: Infertility in mice induced by a recombinant ectromelia virus expressing mouse zona pellucida glycoprotein 3. Biol. Reprod. (1998) 58:152-159.
    • (1998) Biol. Reprod. , vol.58 , pp. 152-159
    • Jackson, R.J.1    Maguire, D.J.2    Hinds, L.A.3    Ramshaw, I.A.4
  • 19
    • 0029964521 scopus 로고    scopus 로고
    • The potential of the zona pellucida as a target for immunocontraception
    • AITKEN RJ, PATERSON M, VAN DUIN M: The potential of the zona pellucida as a target for immunocontraception. Am. J. Reprod. Immunol. (1996) 35:175-180.
    • (1996) Am. J. Reprod. Immunol. , vol.35 , pp. 175-180
    • Aitken, R.J.1    Paterson, M.2    Van Duin, M.3
  • 20
    • 0037206376 scopus 로고    scopus 로고
    • Immunocontraceptive vaccines for human use
    • AITKEN RJ: Immunocontraceptive vaccines for human use. J. Reprod Immunol. (2002) 57:273-287. Recent review of the status of contraceptive vaccines targeting the ZP, sperm surface and implanting embryo.
    • (2002) J. Reprod Immunol. , vol.57 , pp. 273-287
    • Aitken, R.J.1
  • 21
    • 0032809079 scopus 로고    scopus 로고
    • Infertility in female rabbits (Oryctolagus cuniculus) alloimmunized with the rabbit zona pellucida protein ZPB either as a purified recombinant protein or expressed by recombinant myxoma virus
    • KERR PJ, JACKSON RJ, ROBINSON AJ et al.: Infertility in female rabbits (Oryctolagus cuniculus) alloimmunized with the rabbit zona pellucida protein ZPB either as a purified recombinant protein or expressed by recombinant myxoma virus. Biol. Reprod. (1999) 61:606-613.
    • (1999) Biol. Reprod. , vol.61 , pp. 606-613
    • Kerr, P.J.1    Jackson, R.J.2    Robinson, A.J.3
  • 22
    • 0026703638 scopus 로고
    • Histology of ovaries of female rabbits immunized with deglycosylated zona pellucida macromolecules of pigs
    • JONES GR, SACCO AG, SUBRAMANIAN MG et al.: Histology of ovaries of female rabbits immunized with deglycosylated zona pellucida macromolecules of pigs. J. Reprod. Fertil. (1992) 95:513-525.
    • (1992) J. Reprod. Fertil. , vol.95 , pp. 513-525
    • Jones, G.R.1    Sacco, A.G.2    Subramanian, M.G.3
  • 23
    • 0026572079 scopus 로고
    • Analysis of the contraceptive potential of antibodies against native and deglycosylated porcine ZP3 in vivo and in vitro
    • PATERSON M, KOOTHAN PT, MORRIS KD et al.: Analysis of the contraceptive potential of antibodies against native and deglycosylated porcine ZP3 in vivo and in vitro. Biol. Reprod (1992) 46:523-534. This paper clearly demonstrates that the ovarian pathology associated with the induction of active immunity against ZP antigens is not dependent on glycosylation, but is triggered by antibodies directed against the peptide core of these molecules.
    • (1992) Biol. Reprod. , vol.46 , pp. 523-534
    • Paterson, M.1    Koothan, P.T.2    Morris, K.D.3
  • 24
    • 0028832352 scopus 로고
    • Frequency of molecular mimicry among T cell peptides as the basis for autoimmune disease and autoantibody induction
    • GARZA KM, TUNG KS: Frequency of molecular mimicry among T cell peptides as the basis for autoimmune disease and autoantibody induction. J. Immunol. (1995) 155:5444-5448.
    • (1995) J. Immunol. , vol.155 , pp. 5444-5448
    • Garza, K.M.1    Tung, K.S.2
  • 25
    • 0029051909 scopus 로고
    • A zona pellucida 3 peptide vaccine induces antibodies and reversible infertility without ovarian pathology
    • LOU Y, ANG J, THAI H, MCELVEEN F, TUNG KS: A zona pellucida 3 peptide vaccine induces antibodies and reversible infertility without ovarian pathology. J. Immunol. (1995) 155:2715-27120.
    • (1995) J. Immunol. , vol.155 , pp. 2715-27120
    • Lou, Y.1    Ang, J.2    Thai, H.3    Mcelveen, F.4    Tung, K.S.5
  • 26
    • 0036271828 scopus 로고    scopus 로고
    • The contraceptive potential of ZP3 and ZP3 peptides in a primate model
    • PATERSON M, JENNINGS Z, WILSON MR, AITKEN RJ: The contraceptive potential of ZP3 and ZP3 peptides in a primate model. J. Reprod. Immunol. (2002) 53:99-107.
    • (2002) J. Reprod. Immunol. , vol.53 , pp. 99-107
    • Paterson, M.1    Jennings, Z.2    Wilson, M.R.3    Aitken, R.J.4
  • 27
    • 0031045375 scopus 로고    scopus 로고
    • Immunogenicity and contraceptive potential of a human zona pellucida 3 peptide vaccine
    • BAGAVANT H, FUSI FM, BAISCH J, KURTH B, DAVID CS, TUNG KS: Immunogenicity and contraceptive potential of a human zona pellucida 3 peptide vaccine. Biol. Reprod. (1997) 56:764-770.
    • (1997) Biol. Reprod. , vol.56 , pp. 764-770
    • Bagavant, H.1    Fusi, F.M.2    Baisch, J.3    Kurth, B.4    David, C.S.5    Tung, K.S.6
  • 28
    • 0022370228 scopus 로고
    • Population study of causes, treatment and outcome of infertility
    • HULL MGR, GLAZENER CMA, KELLY NJ et al.: Population study of causes, treatment and outcome of infertility. Br. Med. J. (1985) 291:1693-1697.
    • (1985) Br. Med. J. , vol.291 , pp. 1693-1697
    • Hull, M.G.R.1    Glazener, C.M.A.2    Kelly, N.J.3
  • 29
    • 0000238998 scopus 로고
    • Temporary sterilization by the injection of human spermatozoa. A preliminary report
    • BASKIN MJ: Temporary sterilization by the injection of human spermatozoa. A preliminary report. Am. J. Obst. Gyn. (1932) 24:892-897. Historically important paper demonstrating that human semen contains antigens with contraceptive potential
    • (1932) Am. J. Obst. Gyn. , vol.24 , pp. 892-897
    • Baskin, M.J.1
  • 31
    • 0016665078 scopus 로고
    • Low fertility rate in vasovasostomized males and its possible immunologic mechanism
    • GUPTA I, DHAWAN S, GOEL GD, SAHA K: Low fertility rate in vasovasostomized males and its possible immunologic mechanism. Int. J. Fertil. (1975) 20:183-191.
    • (1975) Int. J. Fertil. , vol.20 , pp. 183-191
    • Gupta, I.1    Dhawan, S.2    Goel, G.D.3    Saha, K.4
  • 32
    • 0019864895 scopus 로고
    • Inhibition of fertility and sperm-zona binding by antiserum to the rabbit sperm membrane autoantigen RSA-1
    • O'RAND MG: Inhibition of fertility and sperm-zona binding by antiserum to the rabbit sperm membrane autoantigen RSA-1. Biol. Reprod (1981) 25:621-628.
    • (1981) Biol. Reprod. , vol.25 , pp. 621-628
    • O'Rand, M.G.1
  • 33
    • 0023815181 scopus 로고
    • Fully effective contraception in male and female guinea pigs immunized with the sperm protein PH-20
    • PRIMAKOFF P, LATHROP W, WOOLMAN L, COWAN A, MYLES DG: Fully effective contraception in male and female guinea pigs immunized with the sperm protein PH-20. Nature (1988) 35:543-546.
    • (1988) Nature , vol.35 , pp. 543-546
    • Primakoff, P.1    Lathrop, W.2    Woolman, L.3    Cowan, A.4    Myles, D.G.5
  • 34
    • 0023100910 scopus 로고
    • Identification and purification of a sperm surface protein with a potential role in sperm-egg membrane fusion
    • PRIMAKOFF P, HYATT H, TREDICK-KLINE J: Identification and purification of a sperm surface protein with a potential role in sperm-egg membrane fusion. J. Cell Biol. (1987) 104:141-149.
    • (1987) J. Cell Biol. , vol.104 , pp. 141-149
    • Primakoff, P.1    Hyatt, H.2    Tredick-Kline, J.3
  • 35
    • 0026723158 scopus 로고
    • Design and immunological properties of topographic immunogenic determinants of a protein antigen (LDH-C4) as vaccines
    • KUAMAYA PTP, VAN BUSKIRK AM, GOLDBERG E, PIERCE SK: Design and immunological properties of topographic immunogenic determinants of a protein antigen (LDH-C4) as vaccines. J. Biol. Chem. (1992) 267:6338-6346.
    • (1992) J. Biol. Chem. , vol.267 , pp. 6338-6346
    • Kuamaya, P.T.P.1    Van Buskirk, A.M.2    Goldberg, E.3    Pierce, S.K.4
  • 36
    • 0025230719 scopus 로고
    • Biochemical and morphological characterisation of the intra-acrosomal antigen SP-10 from human sperm
    • HERR JC, FLICKINGER CJ, HOMYK M, KLOTZ K, JOHN E: Biochemical and morphological characterisation of the intra-acrosomal antigen SP-10 from human sperm. Biol. Reprod (1990) 42:181-193.
    • (1990) Biol. Reprod. , vol.42 , pp. 181-193
    • Herr, J.C.1    Flickinger, C.J.2    Homyk, M.3    Klotz, K.4    John, E.5
  • 37
    • 0025075878 scopus 로고
    • Identification of a ZP3-binding protein on acrosome-intact mouse sperm by photoaffinity crosslinking
    • BLEIL JD, WASSARMAN PM: Identification of a ZP3-binding protein on acrosome-intact mouse sperm by photoaffinity crosslinking. Proc. Natl. Acad. Sci. USA (1990) 87:5563-5567.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5563-5567
    • Bleil, J.D.1    Wassarman, P.M.2
  • 38
    • 0028072484 scopus 로고
    • Antibodies to sperm-specific human FA-1 inhibit in vitro fertilization in rhesus monkeys: Development of a simian model for testing of anti-FA-1 contraceptive vaccine
    • NAZ RK, WOLF DP: Antibodies to sperm-specific human FA-1 inhibit in vitro fertilization in rhesus monkeys: development of a simian model for testing of anti-FA-1 contraceptive vaccine. J. Reprod. Immunol. (1994) 27:111-121.
    • (1994) J. Reprod. Immunol. , vol.27 , pp. 111-121
    • Naz, R.K.1    Wolf, D.P.2
  • 39
    • 0031158227 scopus 로고    scopus 로고
    • Characterization and isolation of SOB2, a human sperm protein with a potential role in oocyte membrane binding
    • LEFEVRE A, MARTIN RUIZ C, CHOKOMIAN S, DUQUENNE C, FINAZ C: Characterization and isolation of SOB2, a human sperm protein with a potential role in oocyte membrane binding. Mol. Hum. Reprod (1997) 3:507-516.
    • (1997) Mol. Hum. Reprod. , vol.3 , pp. 507-516
    • Lefevre, A.1    Martin Ruiz, C.2    Chokomian, S.3    Duquenne, C.4    Finaz, C.5
  • 40
    • 0032744020 scopus 로고    scopus 로고
    • Evidence for a unique N-linked glycan associated with human infertility on sperm CD52: A candidate contraceptive vaccinogen
    • DIEKMAN AB, NORTON EJ, KLOTZ KL, WESTBROOK VA, HERR JC: Evidence for a unique N-linked glycan associated with human infertility on sperm CD52: a candidate contraceptive vaccinogen. Immunol. Rev. (1999) 171:203-211.
    • (1999) Immunol. Rev. , vol.171 , pp. 203-211
    • Diekman, A.B.1    Norton, E.J.2    Klotz, K.L.3    Westbrook, V.A.4    Herr, J.C.5
  • 41
    • 0037119363 scopus 로고    scopus 로고
    • Mouse sperm lacking cell surface hyaluronidase PH-20 can pass through the layer of cumulus cells and fertilize the egg
    • BABA D, KASHIWABARA S, HONDA A et al.: Mouse sperm lacking cell surface hyaluronidase PH-20 can pass through the layer of cumulus cells and fertilize the egg. J. Biol. Chem. (2002) 277:30310-30314. Important paper indicating that PH20 is not essential for fertilisation and, therefore, not a candidate for contraceptive vaccine development.
    • (2002) J. Biol. Chem. , vol.277 , pp. 30310-30314
    • Baba, D.1    Kashiwabara, S.2    Honda, A.3
  • 42
    • 0030979136 scopus 로고    scopus 로고
    • Mechanism of infertility in male guinea pigs immunized with sperm PH-20
    • TUNG KS, PRIMAKOFF P, WOOLMAN-GAMER L, MYLES DG: Mechanism of infertility in male guinea pigs immunized with sperm PH-20. Biol. Reprod. (1997) 56:1133-1141.
    • (1997) Biol. Reprod. , vol.56 , pp. 1133-1141
    • Tung, K.S.1    Primakoff, P.2    Woolman-Gamer, L.3    Myles, D.G.4
  • 43
    • 0031006420 scopus 로고    scopus 로고
    • Selection of antigens for use in a virus-vectored immunocontraceptive vaccine: PH-20 as a case study
    • HOLLAND MK, ANDREWS J, CLARKE H, WALTON C, HINDS LA: Selection of antigens for use in a virus-vectored immunocontraceptive vaccine: PH-20 as a case study. Reprod. Fertil. Dev. (1997) 9:117-124.
    • (1997) Reprod. Fertil. Dev. , vol.9 , pp. 117-124
    • Holland, M.K.1    Andrews, J.2    Clarke, H.3    Walton, C.4    Hinds, L.A.5
  • 44
    • 0036240345 scopus 로고    scopus 로고
    • Restricted entry of IgG into male and female rabbit reproductive ducts following immunization with recombinant rabbit PH-20
    • POMERING M, JONES RC, HOLLAND MK, BLAKE AE, BEAGLEY KWP: Restricted entry of IgG into male and female rabbit reproductive ducts following immunization with recombinant rabbit PH-20. Am. J. Reprod. Immunol. (2002) 47:174-182.
    • (2002) Am. J. Reprod. Immunol. , vol.47 , pp. 174-182
    • Pomering, M.1    Jones, R.C.2    Holland, M.K.3    Blake, A.E.4    Beagley, K.W.P.5
  • 45
    • 0033764080 scopus 로고    scopus 로고
    • Mouse Spaml (PH-20): Evidence for its expression in the epididymis and for a new category of spermatogenic-expressed genes
    • DENG X, HE Y, MARTIN-DELEON PA: Mouse Spaml (PH-20): evidence for its expression in the epididymis and for a new category of spermatogenic-expressed genes. J. Androl. (2000) 21:822-832.
    • (2000) J. Androl. , vol.21 , pp. 822-832
    • Deng, X.1    He, Y.2    Martin-Deleon, P.A.3
  • 46
    • 0038408329 scopus 로고    scopus 로고
    • Mouse Epididymal Spam1 (PH-20) is released in the luminal fluid with its lipid anchor
    • ZHANG H, MARTIN-DELEON PA: Mouse Epididymal Spam1 (PH-20) is released in the luminal fluid with its lipid anchor. J. Androl. (2003) 24:51-58.
    • (2003) J. Androl. , vol.24 , pp. 51-58
    • Zhang, H.1    Martin-Deleon, P.A.2
  • 47
    • 0037962077 scopus 로고    scopus 로고
    • Mouse Spam1 (PH-20) is a multifunctional protein: Evidence for its expression in the Female reproductive tract
    • e-Pub ahead of print
    • ZHANG H, MARTIN-DELEON PA: Mouse Spam1 (PH-20) is a multifunctional protein: Evidence for its expression in the Female reproductive tract. Biol. Reprod. (2003) (e-Pub ahead of print).
    • (2003) Biol. Reprod.
    • Zhang, H.1    Martin-Deleon, P.A.2
  • 48
    • 0028888304 scopus 로고
    • Reversible contraception in female baboons immunized with a synthetic epitope of sperm-specific lactate dehydrogenase
    • O'HERN PA, BAMBRA CS, ISAHAKIA M, GOLDBERG E: Reversible contraception in female baboons immunized with a synthetic epitope of sperm-specific lactate dehydrogenase. Biol. Reprod. (1995) 52:331-339.
    • (1995) Biol. Reprod. , vol.52 , pp. 331-339
    • O'Hern, P.A.1    Bambra, C.S.2    Isahakia, M.3    Goldberg, E.4
  • 49
    • 0030846202 scopus 로고    scopus 로고
    • Colinear synthesis of an antigen-specific B-cell epitope with a 'promiscuous' tetanus toxin T-cell epitope: A synthetic peptide immunocontraceptive
    • O'HERN PA, LIANG ZG, BAMBRA CS, GOLDBERG E: Colinear synthesis of an antigen-specific B-cell epitope with a 'promiscuous' tetanus toxin T-cell epitope: a synthetic peptide immunocontraceptive. Vaccine (1997) 15:1761-1766.
    • (1997) Vaccine , vol.15 , pp. 1761-1766
    • O'Hern, P.A.1    Liang, Z.G.2    Bambra, C.S.3    Goldberg, E.4
  • 50
    • 0028691932 scopus 로고
    • Autoimmune-like activity of sperm specific LDH: A pathophysiological and electron microscopic study of atrophied testis and epididymis
    • GUPTA GS, MALHOTRA R: Autoimmune-like activity of sperm specific LDH: a pathophysiological and electron microscopic study of atrophied testis and epididymis. Indian J. Biochem. Biophys. (1994) 31:480-485.
    • (1994) Indian J. Biochem. Biophys. , vol.31 , pp. 480-485
    • Gupta, G.S.1    Malhotra, R.2
  • 52
    • 0036694444 scopus 로고    scopus 로고
    • Update on sperm antigen-based contraceptive vaccines
    • HERR J: Update on sperm antigen-based contraceptive vaccines. Immunol. Allergy Clin North Am. (2002) 22:503-527.
    • (2002) Immunol. Allergy Clin North Am. , vol.22 , pp. 503-527
    • Herr, J.1
  • 53
    • 0028227343 scopus 로고
    • Sperm-egg recognition in the mouse: Characterization of sp56, a sperm protein having specific affinity for ZP3
    • CHENG A, LE T, PALACIOS M et al.: Sperm-egg recognition in the mouse: characterization of sp56, a sperm protein having specific affinity for ZP3. J. Cell Biol. (1994) 125:867-878.
    • (1994) J. Cell Biol. , vol.125 , pp. 867-878
    • Cheng, A.1    Le, T.2    Palacios, M.3
  • 54
    • 0032923491 scopus 로고    scopus 로고
    • Expression of recombinant mouse sperm protein sp56 and assessment of its potential for use as an antigen in an immunocontraceptive vaccine
    • HARDY CM, MOBBS KJ: Expression of recombinant mouse sperm protein sp56 and assessment of its potential for use as an antigen in an immunocontraceptive vaccine. Mol. Reprod Dev. (1999) 52:216-224.
    • (1999) Mol. Reprod Dev. , vol.52 , pp. 216-224
    • Hardy, C.M.1    Mobbs, K.J.2
  • 55
    • 0035168574 scopus 로고    scopus 로고
    • Mouse sperm protein sp56 is a component of the acrosomal matrix
    • KIM KS, CHA MC, GERTON GL: Mouse sperm protein sp56 is a component of the acrosomal matrix. Biol. Reprod. (2001) 64:36-43.
    • (2001) Biol. Reprod. , vol.64 , pp. 36-43
    • Kim, K.S.1    Cha, M.C.2    Gerton, G.L.3
  • 56
    • 0035023871 scopus 로고    scopus 로고
    • Association of egg zona pellucida glycoprotein mZP3 with sperm protein sp56 during fertilization in mice
    • COHEN N, WASSARMAN PM: Association of egg zona pellucida glycoprotein mZP3 with sperm protein sp56 during fertilization in mice. Int. J. Dev. Biol. (2001) 45:569-576.
    • (2001) Int. J. Dev. Biol. , vol.45 , pp. 569-576
    • Cohen, N.1    Wassarman, P.M.2
  • 57
    • 0026510747 scopus 로고
    • A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion
    • BLOBEL CP, WOLFSBERG TG, TURCK CW, MYLES DG, PRIMAKOFF P, WHITE JM: A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion. Nature (1992) 356:248-252.
    • (1992) Nature , vol.356 , pp. 248-252
    • Blobel, C.P.1    Wolfsberg, T.G.2    Turck, C.W.3    Myles, D.G.4    Primakoff, P.5    White, J.M.6
  • 58
    • 0029045064 scopus 로고
    • ADAM, a widely distributed and developmentally regulated gene family encoding membrane proteins with a disintegrin and metalloprotease domain
    • WOLFSBERG TG, STRAIGHT PD, GERENA RL et al.: ADAM, a widely distributed and developmentally regulated gene family encoding membrane proteins with a disintegrin and metalloprotease domain. Dev. Biol. (1995) 169:378-383.
    • (1995) Dev. Biol. , vol.169 , pp. 378-383
    • Wolfsberg, T.G.1    Straight, P.D.2    Gerena, R.L.3
  • 59
    • 0030767188 scopus 로고    scopus 로고
    • Rat MDC family of proteins: Sequence analysis, tissue distribution, and expression in prepubertal and adult rat testis
    • FRAYNE J, JURY JA, BARKER HL, HALL L: Rat MDC family of proteins: sequence analysis, tissue distribution, and expression in prepubertal and adult rat testis. Mol. Reprod. Dev. (1997) 48:159-167.
    • (1997) Mol. Reprod. Dev. , vol.48 , pp. 159-167
    • Frayne, J.1    Jury, J.A.2    Barker, H.L.3    Hall, L.4
  • 60
    • 0028325475 scopus 로고
    • Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion
    • MYLES DG, KIMMEL LH, BLOBEL CP, WHITE JM, PRIMAKOFF P: Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion. Proc. Natl. Acad. Sci. USA (1994) 91:4195-4198.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4195-4198
    • Myles, D.G.1    Kimmel, L.H.2    Blobel, C.P.3    White, J.M.4    Primakoff, P.5
  • 61
    • 0031778296 scopus 로고    scopus 로고
    • Roles of the disintegrin domains of mouse fertilins alpha and beta in fertilization
    • EVANS JP, SCHULTZ RM, KOPF GS: Roles of the disintegrin domains of mouse fertilins alpha and beta in fertilization. Biol. Reprod. (1998) 59:145-152.
    • (1998) Biol. Reprod. , vol.59 , pp. 145-152
    • Evans, J.P.1    Schultz, R.M.2    Kopf, G.S.3
  • 62
    • 0030069394 scopus 로고    scopus 로고
    • Initial evaluation of fertilin as an immunocontraceptive antigen and molecular cloning of the cynomolgus monkey fertilin beta subunit
    • RAMARAO CS, MYLES DG, WHITE JM, PRIMAKOFF P: Initial evaluation of fertilin as an immunocontraceptive antigen and molecular cloning of the cynomolgus monkey fertilin beta subunit. Mol. Reprod. Dev. (1996) 43:70-75.
    • (1996) Mol. Reprod. Dev. , vol.43 , pp. 70-75
    • Ramarao, C.S.1    Myles, D.G.2    White, J.M.3    Primakoff, P.4
  • 63
    • 0030885960 scopus 로고    scopus 로고
    • Examination of the immunocontraceptive potential of recombinant rabbit fertilin subunits in rabbit
    • HARDY CM, CLARKE HG, NIXON B, GRIGG JA, HINDS LA, HOLLAND MK: Examination of the immunocontraceptive potential of recombinant rabbit fertilin subunits in rabbit. Biol. Reprod. (1997) 57:879-886.
    • (1997) Biol. Reprod. , vol.57 , pp. 879-886
    • Hardy, C.M.1    Clarke, H.G.2    Nixon, B.3    Grigg, J.A.4    Hinds, L.A.5    Holland, M.K.6
  • 64
    • 0037442567 scopus 로고    scopus 로고
    • None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm-egg binding and fusion
    • HE ZY, BRAKEBUSCH C, FASSLER R, KREIDBERG JA, PRIMAKOFF P, MYLES DG: None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm-egg binding and fusion. Dev. Biol. (2003) 254:226-237. Recent demonstration that neither integrins on the surface of the oocyte, nor presumably the sperm ADAM proteins that target them, are involved in sperm-oocyte fusion. These molecules, therefore, are unlikely to be effective targets for contraceptive vaccines.
    • (2003) Dev. Biol. , vol.254 , pp. 226-237
    • He, Z.Y.1    Brakebusch, C.2    Fassler, R.3    Kreidberg, J.A.4    Primakoff, P.5    Myles, D.G.6
  • 65
    • 0035070684 scopus 로고    scopus 로고
    • Do fertilin beta and cyritestin play a major role in mammalian sperm-oolemma interactions? A critical re-evaluation of the use of peptide mimics in identifying specific oocyte recognition proteins
    • MCLAUGHLIN EA, FRAYNE J, BLOOMERG G, HALL L: Do fertilin beta and cyritestin play a major role in mammalian sperm-oolemma interactions? A critical re-evaluation of the use of peptide mimics in identifying specific oocyte recognition proteins. Mol. Hum. Reprod. (2001) 7:313-317.
    • (2001) Mol. Hum. Reprod. , vol.7 , pp. 313-317
    • Mclaughlin, E.A.1    Frayne, J.2    Bloomerg, G.3    Hall, L.4
  • 66
    • 0031059822 scopus 로고    scopus 로고
    • The human fertilin alpha gene is non-functional: Implications for its proposed role in fertilization
    • JURY JA, FRAYNE J, HALL L: The human fertilin alpha gene is non-functional: implications for its proposed role in fertilization. Biochem. J. (1997) 321:577-581.
    • (1997) Biochem. J. , vol.321 , pp. 577-581
    • Jury, J.A.1    Frayne, J.2    Hall, L.3
  • 67
    • 0030722857 scopus 로고    scopus 로고
    • Fertility regulating and immunotherapeutic vaccines reaching human trials stage
    • TALWAR GP: Fertility regulating and immunotherapeutic vaccines reaching human trials stage. Hum. Reprod. Update (1997) 3:301-310. Review of the status of contraceptive vaccines targeting hCG.
    • (1997) Hum. Reprod. Update , vol.3 , pp. 301-310
    • Talwar, G.P.1
  • 68
    • 0031862156 scopus 로고    scopus 로고
    • Regain of fertility and normality of progeny born during below protective threshold antibody titers in women immunized with the HSD-hCG vaccine
    • SINGH M, DAS SK, SURI S, SINGH O, TALWAR GP: Regain of fertility and normality of progeny born during below protective threshold antibody titers in women immunized with the HSD-hCG vaccine. Am. J. Reprod. Immunol. (1998) 39:395-398.
    • (1998) Am. J. Reprod. Immunol. , vol.39 , pp. 395-398
    • Singh, M.1    Das, S.K.2    Suri, S.3    Singh, O.4    Talwar, G.P.5
  • 69
    • 0033771721 scopus 로고    scopus 로고
    • Humoral hyporesponsiveness to a conjugate contraceptive vaccine and its bypass by diverse carriers using permissible adjuvant
    • MANDOKHOT A, PAL R, NAGPAL S, CHAUHAN VS, AHLAWAT S, SINGH O: Humoral hyporesponsiveness to a conjugate contraceptive vaccine and its bypass by diverse carriers using permissible adjuvant. Clin. Exp. Immunol. (2000) 122:101-108.
    • (2000) Clin. Exp. Immunol. , vol.122 , pp. 101-108
    • Mandokhot, A.1    Pal, R.2    Nagpal, S.3    Chauhan, V.S.4    Ahlawat, S.5    Singh, O.6
  • 70
    • 0033999554 scopus 로고    scopus 로고
    • Reversible protection of disulfide bonds followed by oxidative folding render recombinant hCG beta highly immunogenic
    • MUKHOPADHYAY A: Reversible protection of disulfide bonds followed by oxidative folding render recombinant hCG beta highly immunogenic. Vaccine (2000) 18:1802-1810.
    • (2000) Vaccine , vol.18 , pp. 1802-1810
    • Mukhopadhyay, A.1
  • 71
    • 0034993246 scopus 로고    scopus 로고
    • High expression of human chorionic gonadotrophin beta-subunit using a synthetic vaccinia virus promoter
    • GUPTA A, CHANDRASEKHAR S, PAL R, AHLAWAT S, SINGH O: High expression of human chorionic gonadotrophin beta-subunit using a synthetic vaccinia virus promoter. J. Mol. Endocrinol. (2001) 26:281-287
    • (2001) J. Mol. Endocrinol. , vol.26 , pp. 281-287
    • Gupta, A.1    Chandrasekhar, S.2    Pal, R.3    Ahlawat, S.4    Singh, O.5
  • 72
    • 0035020393 scopus 로고    scopus 로고
    • Refocusing of B-cell responses following a single amino acid substitution in an antigen
    • CHIESA MD, MARTENSEN PM, SIMMONS C et al.: Refocusing of B-cell responses following a single amino acid substitution in an antigen. Immunology (2001) 103:172-178. An example of how careful modification of a peptide antigen can redirect the immune response to achieve an improvement in target specificity.
    • (2001) Immunology , vol.103 , pp. 172-178
    • Chiesa, M.D.1    Martensen, P.M.2    Simmons, C.3
  • 73
    • 0033529616 scopus 로고    scopus 로고
    • Prior immunity to a carrier enhances antibody responses to hCG in recipients of an hCG-carrier conjugate vaccine
    • SHAH S, RAGHUPATHY R, SINGH O, TALWAR GP, SODHI A et al.: Prior immunity to a carrier enhances antibody responses to hCG in recipients of an hCG-carrier conjugate vaccine. Vaccine (1999) 17:3116-3123.
    • (1999) Vaccine , vol.17 , pp. 3116-3123
    • Shah, S.1    Raghupathy, R.2    Singh, O.3    Talwar, G.P.4    Sodhi, A.5
  • 74
    • 0030978050 scopus 로고    scopus 로고
    • Responsiveness of human male volunteers to immunization with ovine follicle stimulating hormone vaccine: Results of a pilot study
    • MOUDGAL NR, MURTHY GS, PRASANNA KUMAR KM et al.: Responsiveness of human male volunteers to immunization with ovine follicle stimulating hormone vaccine: results of a pilot study. Hum. Reprod. (1997) 12:457-463.
    • (1997) Hum. Reprod. , vol.12 , pp. 457-463
    • Moudgal, N.R.1    Murthy, G.S.2    Prasanna Kumar, K.M.3
  • 75
    • 0036839103 scopus 로고    scopus 로고
    • Highly immunogenic and totally synthetic lipopeptides as self-adjuvanting immunocontraceptive vaccines
    • ZENG W, GHOSH S, LAU YF, BROWN LE, JACKSON DC: Highly immunogenic and totally synthetic lipopeptides as self-adjuvanting immunocontraceptive vaccines. J. Immunol. (2002) 169:4905-4912.
    • (2002) J. Immunol. , vol.169 , pp. 4905-4912
    • Zeng, W.1    Ghosh, S.2    Lau, Y.F.3    Brown, L.E.4    Jackson, D.C.5
  • 77
    • 0021801180 scopus 로고
    • The oral immune system under normal and pathological conditions
    • BRANDTZAEG P: The oral immune system under normal and pathological conditions. Pathol. Res. Pract. (1985) 179:619-621.
    • (1985) Pathol. Res. Pract. , vol.179 , pp. 619-621
    • Brandtzaeg, P.1
  • 78
    • 0023190922 scopus 로고
    • Intravascular and mucosal immunoglobulin A: Two separate but related systems of immune defence?
    • CONLEY ME, DELACROIX DL: Intravascular and mucosal immunoglobulin A: two separate but related systems of immune defence? Ann. Intern. Med. (1987) 106:892-899.
    • (1987) Ann. Intern. Med. , vol.106 , pp. 892-899
    • Conley, M.E.1    Delacroix, D.L.2
  • 79
  • 80
    • 0002281951 scopus 로고    scopus 로고
    • The concept of mucosal immunology
    • Bronson RA, Alexander NJ, Anderson DJ, Branch DW, Kutteh WH (Eds), Blackwell Science Ltd, Oxford
    • KUTTEH WH, MESTECKY J: The concept of mucosal immunology. In: Reproductive Immunology Bronson RA, Alexander NJ, Anderson DJ, Branch DW, Kutteh WH (Eds), Blackwell Science Ltd, Oxford (1996):28-51. A thorough review of mucosal immunity.
    • (1996) Reproductive Immunology , pp. 28-51
    • Kutteh, W.H.1    Mestecky, J.2
  • 82
    • 0031251985 scopus 로고    scopus 로고
    • Challenges for vaccination against sexually-transmitted diseases: Induction and long-term maintenance of mucosal immune responses in the female genital tract
    • ROSENTHAL KL, GALLICHAN WS: Challenges for vaccination against sexually-transmitted diseases: induction and long-term maintenance of mucosal immune responses in the female genital tract. Semin. Immunol. (1997) 9:303-314.
    • (1997) Semin. Immunol. , vol.9 , pp. 303-314
    • Rosenthal, K.L.1    Gallichan, W.S.2
  • 83
    • 0029897935 scopus 로고    scopus 로고
    • Salivary, nasal, genital, and systemic antibody responses in monkeys immunized intranasally with a bacterial protein antigen and the Cholera toxin B subunic
    • RUSSELL MW, MOLDOVEANU Z, WHITE PL, SIBERT GJ, MESTECKY J, MICHALEK SM: Salivary, nasal, genital, and systemic antibody responses in monkeys immunized intranasally with a bacterial protein antigen and the Cholera toxin B subunic. Infect. Immun. (1996) 64:1272-1283. Paper demonstrating the feasibility of inducing generalised IgA antibody responses in the mucosal immune system through the intranasal administration of antigen.
    • (1996) Infect. Immun. , vol.64 , pp. 1272-1283
    • Russell, M.W.1    Moldoveanu, Z.2    White, P.L.3    Sibert, G.J.4    Mestecky, J.5    Michalek, S.M.6
  • 84
    • 0034015671 scopus 로고    scopus 로고
    • Mucosal and systemic antibody responses after peroral or intranasal immunization: Effects of conjugation to enterotoxin B subunits and/or of co-administration with free toxin as adjuvant
    • RASK C, FREDRIKSSON M, LINDBLAD M, CZERKINSKY C, HOLMGREN J: Mucosal and systemic antibody responses after peroral or intranasal immunization: effects of conjugation to enterotoxin B subunits and/or of co-administration with free toxin as adjuvant. APMIS (2000) 108:178-186.
    • (2000) APMIS , vol.108 , pp. 178-186
    • Rask, C.1    Fredriksson, M.2    Lindblad, M.3    Czerkinsky, C.4    Holmgren, J.5
  • 85
    • 0033024523 scopus 로고    scopus 로고
    • Characterization of immunoglobulins and cytokines in human cervical mucus: Influence of exogenous and endogenous hormones
    • FRANKLIN RD, KUTTEH WH: Characterization of immunoglobulins and cytokines in human cervical mucus: influence of exogenous and endogenous hormones. J. Reprod. Immunol. (1999) 42:93-106.
    • (1999) J. Reprod. Immunol. , vol.42 , pp. 93-106
    • Franklin, R.D.1    Kutteh, W.H.2
  • 86
    • 0024338548 scopus 로고
    • Regulation of IgA synthesis and immune response by T cells and interleukins
    • MCGHEE JR, MESTECKY J, ELSON CO, KIYONO H: Regulation of IgA synthesis and immune response by T cells and interleukins. J. Clin. Immunol. (1989) 9:175-199.
    • (1989) J. Clin. Immunol. , vol.9 , pp. 175-199
    • Mcghee, J.R.1    Mestecky, J.2    Elson, C.O.3    Kiyono, H.4
  • 87
    • 0025888942 scopus 로고
    • Cytokine regulation of the mucosal immune system: In vivo stimulation by interferon-gamma of secretory component and immunoglobulin A in uterine secretions and proliferation of lymphocytes from spleen
    • PRABHALA RH, WIRA CR: Cytokine regulation of the mucosal immune system: in vivo stimulation by interferon-gamma of secretory component and immunoglobulin A in uterine secretions and proliferation of lymphocytes from spleen. Endocrinology (1991) 129:2915-2923.
    • (1991) Endocrinology , vol.129 , pp. 2915-2923
    • Prabhala, R.H.1    Wira, C.R.2
  • 88
    • 0029123973 scopus 로고
    • Influence of estrous cycle and estradiol on mitogenic responses of splenic T- and B-lymphocytes
    • PRABHALA RH, WIRA CR: Influence of estrous cycle and estradiol on mitogenic responses of splenic T- and B-lymphocytes. Adv. Exp. Med. Biol. (1995) 371A:379-381.
    • (1995) Adv. Exp. Med. Biol. , vol.371 A , pp. 379-381
    • Prabhala, R.H.1    Wira, C.R.2
  • 89
    • 0031968159 scopus 로고    scopus 로고
    • Mucosal immunity in the female reproductive tract: Correlation of immunoglobulins, cytokines, and reproductive hormones in human cervical mucus around the time of ovulation
    • KUTTEH WH, MOLDOVEANU Z, MESTECKY J et al.: Mucosal immunity in the female reproductive tract: correlation of immunoglobulins, cytokines, and reproductive hormones in human cervical mucus around the time of ovulation. AIDS Res. Hum. Retroviruses (1998) 14(Suppl. 1):S51-S55.
    • (1998) AIDS Res. Hum. Retroviruses , vol.14 , Issue.SUPPL. 1
    • Kutteh, W.H.1    Moldoveanu, Z.2    Mestecky, J.3
  • 90
    • 0029093554 scopus 로고
    • T lymphocytes infiltrating advanced grades of cervical neoplasia. CD8-positive cells are recruited to invasion
    • EDWARDS RP, KUYKENDALL K, CROWLEY-NOWICK P, PARTRIDGE EE, SHINGLETON HM, MESTECKY J: T lymphocytes infiltrating advanced grades of cervical neoplasia. CD8-positive cells are recruited to invasion. Cancer (1995) 76:1411-1415.
    • (1995) Cancer , vol.76 , pp. 1411-1415
    • Edwards, R.P.1    Kuykendall, K.2    Crowley-Nowick, P.3    Partridge, E.E.4    Shingleton, H.M.5    Mestecky, J.6
  • 91
    • 0032184817 scopus 로고    scopus 로고
    • Transcutaneous immunization with cholera toxin protects mice against lethal mucosal toxin challenge
    • GLENN GM, SCHARTON-KERSTEN T, VASSELL R, MALLETT CP, HALE TL, ALVING CR: Transcutaneous immunization with cholera toxin protects mice against lethal mucosal toxin challenge. J. Immunol. (1998) 161:3211-3214.
    • (1998) J. Immunol. , vol.161 , pp. 3211-3214
    • Glenn, G.M.1    Scharton-Kersten, T.2    Vassell, R.3    Mallett, C.P.4    Hale, T.L.5    Alving, C.R.6
  • 92
    • 0033009744 scopus 로고    scopus 로고
    • Transcutaneous immunization with bacterial ADP-ribosylating exotoxins as antigens and adjuvants
    • GLENN GM, SCHARTON-KERSTEN T, VASSELL R, MATYAS GR, ALVING CR: Transcutaneous immunization with bacterial ADP-ribosylating exotoxins as antigens and adjuvants. Infect. Immun. (1999) 67:1100-1106.
    • (1999) Infect. Immun. , vol.67 , pp. 1100-1106
    • Glenn, G.M.1    Scharton-Kersten, T.2    Vassell, R.3    Matyas, G.R.4    Alving, C.R.5
  • 93
    • 0034538134 scopus 로고    scopus 로고
    • Transcutaneous immunization induces mucosal and systemic immunity: A potent method for targeting immunity to the female reproductive tract
    • GOCKEL CM, BAO S, BEAGLEY KW: Transcutaneous immunization induces mucosal and systemic immunity: a potent method for targeting immunity to the female reproductive tract. Mol. Immunol. (2000) 37:537-544.
    • (2000) Mol. Immunol. , vol.37 , pp. 537-544
    • Gockel, C.M.1    Bao, S.2    Beagley, K.W.3
  • 95
    • 0035144140 scopus 로고    scopus 로고
    • The common vaccine adjuvant aluminum hydroxide up-regulates accessory properties of human monocytes via an interleukin-4-dependent mechanism
    • ULANOVA M, TARKOWSKI A, HAHN-ZORIC M, HANSON LA: The common vaccine adjuvant aluminum hydroxide up-regulates accessory properties of human monocytes via an interleukin-4-dependent mechanism. Infect. Immun. (2001) 69:1151-1159.
    • (2001) Infect. Immun. , vol.69 , pp. 1151-1159
    • Ulanova, M.1    Tarkowski, A.2    Hahn-Zoric, M.3    Hanson, L.A.4
  • 96
    • 0034624070 scopus 로고    scopus 로고
    • The comparison of the effect of LTR72 and MF59 adjuvants on mouse humoral response to intranasal immunisation with human papillomavirus type 6b (HPV-6b) virus-like particles
    • GREER CE, PETRACCA R, BUONAMASSA DT et al.: The comparison of the effect of LTR72 and MF59 adjuvants on mouse humoral response to intranasal immunisation with human papillomavirus Type 6b (HPV-6b) virus-like particles. Vaccine (2000) 19:1008-1012.
    • (2000) Vaccine , vol.19 , pp. 1008-1012
    • Greer, C.E.1    Petracca, R.2    Buonamassa, D.T.3
  • 97
    • 0035961455 scopus 로고    scopus 로고
    • QS-21 promotes an adjuvant effect allowing for reduced antigen dose during HIV-1 envelope subunit immmunization in humans
    • EVANS TG, MCELRATH MJ, MATTHEWS T et al.: QS-21 promotes an adjuvant effect allowing for reduced antigen dose during HIV-1 envelope subunit immmunization in humans. Vaccine (2001) 19:2080-2091.
    • (2001) Vaccine , vol.19 , pp. 2080-2091
    • Evans, T.G.1    Mcelrath, M.J.2    Matthews, T.3
  • 98
    • 0011017020 scopus 로고    scopus 로고
    • Effect of immunological adjuvant combinations on the antibody and T-cell response to vaccination with MUC1-KLH and GD3-KLH conjugates
    • KIM SK, RAGUPATHI G, CAPPELLO S, KAGAN E, LIVINGSTON PO: Effect of immunological adjuvant combinations on the antibody and T-cell response to vaccination with MUC1-KLH and GD3-KLH conjugates. Vaccine (2000) 19:530-537.
    • (2000) Vaccine , vol.19 , pp. 530-537
    • Kim, S.K.1    Ragupathi, G.2    Cappello, S.3    Kagan, E.4    Livingston, P.O.5
  • 99
    • 0033624828 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides and interleukin-12 improve the efficacy of Mycobacterium boris BCG vaccination in mice challenged with M. tuberculosis
    • FREIDAG BL, MELTON GB, COLLINS F et al.: CpG oligodeoxynucleotides and interleukin-12 improve the efficacy of Mycobacterium boris BCG vaccination in mice challenged with M. tuberculosis. Infect. Immun. (2000) 68:2948-2953.
    • (2000) Infect. Immun. , vol.68 , pp. 2948-2953
    • Freidag, B.L.1    Melton, G.B.2    Collins, F.3
  • 100
  • 101
    • 0034507382 scopus 로고    scopus 로고
    • QS-21 synergizes with recombinant interleukin-12 to create a potent adjuvant formulation for the fusion protein of respiratory syncytial virus
    • HANCOCK GE, HEERS KM, SMITH JD: QS-21 synergizes with recombinant interleukin-12 to create a potent adjuvant formulation for the fusion protein of respiratory syncytial virus. Viral Immunol. (2000) 13:503-509.
    • (2000) Viral Immunol. , vol.13 , pp. 503-509
    • Hancock, G.E.1    Heers, K.M.2    Smith, J.D.3
  • 102
    • 0033664689 scopus 로고    scopus 로고
    • DNA vaccination: Antigen presentation and the induction of immunity
    • SHEDLOCK DJ, WEINER DB: DNA vaccination: antigen presentation and the induction of immunity. J. Leukoc. Biol. (2000) 68:793-806. Review of DNA vaccination strategy.
    • (2000) J. Leukoc. Biol. , vol.68 , pp. 793-806
    • Shedlock, D.J.1    Weiner, D.B.2
  • 104
    • 0034176364 scopus 로고    scopus 로고
    • The prime-boost strategy: Exciting prospects for improved vaccination
    • RAMSHAW IA, RAMSAY AJ: The prime-boost strategy: exciting prospects for improved vaccination. Immunol. Today (2000) 21:163-165.
    • (2000) Immunol. Today , vol.21 , pp. 163-165
    • Ramshaw, I.A.1    Ramsay, A.J.2
  • 105
    • 0034612321 scopus 로고    scopus 로고
    • A fusion DNA vaccine that targets antigen-presenting cells increases protection from viral challenge
    • DELIYANNIS G, BOYLE JS, BRADY JL, BROWN LE, LEW AM: A fusion DNA vaccine that targets antigen-presenting cells increases protection from viral challenge. Proc. Natl. Acad. Sci. USA (2000) 97:6676-6680.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6676-6680
    • Deliyannis, G.1    Boyle, J.S.2    Brady, J.L.3    Brown, L.E.4    Lew, A.M.5
  • 106
    • 0034554842 scopus 로고    scopus 로고
    • Enhanced antitumor immunity by fusion of CTLA-4 to a self tumor antigen
    • HUANG TH, WU PY, LEE CN et al.: Enhanced antitumor immunity by fusion of CTLA-4 to a self tumor antigen. Blood (2000) 96:3663-3670.
    • (2000) Blood , vol.96 , pp. 3663-3670
    • Huang, T.H.1    Wu, P.Y.2    Lee, C.N.3
  • 107
    • 0033962639 scopus 로고    scopus 로고
    • Site-directed immune responses in DNA vaccines encoding ligand-antigen fusions
    • LEW AM, BRADY BJ, BOYLE BJ: Site-directed immune responses in DNA vaccines encoding ligand-antigen fusions. Vaccine (2000) 18:1681-1685.
    • (2000) Vaccine , vol.18 , pp. 1681-1685
    • Lew, A.M.1    Brady, B.J.2    Boyle, B.J.3
  • 108
    • 0030812840 scopus 로고    scopus 로고
    • DNA immunization: Ubiquitination of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody induction
    • RODRIGUEZ F, ZHANG J, WHITTON JL: DNA immunization: ubiquitination of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody induction. J. Virol. (1997) 71:8497-8503.
    • (1997) J. Virol. , vol.71 , pp. 8497-8503
    • Rodriguez, F.1    Zhang, J.2    Whitton, J.L.3
  • 109
    • 0036196972 scopus 로고    scopus 로고
    • Infertility in mice induced by the rhesus monkey chorionic gonadotropin beta-subunit glycoprotein (rmCGbeta) using DNA immunization
    • CHEN Y, LIU Z, YANG Y, CHEN YZ, PENG JP: Infertility in mice induced by the rhesus monkey chorionic gonadotropin beta-subunit glycoprotein (rmCGbeta) using DNA immunization. Mol Cell Biochem. (2002) 231:89-96.
    • (2002) Mol Cell Biochem. , vol.231 , pp. 89-96
    • Chen, Y.1    Liu, Z.2    Yang, Y.3    Chen, Y.Z.4    Peng, J.P.5
  • 110
    • 0037408458 scopus 로고    scopus 로고
    • Construction of the plasmid pCMV4-rZPC' DNA vaccine and analysis of its contraceptive potential
    • XIANG RL, ZHOU F, YANG Y, PENG JP: Construction of the plasmid pCMV4-rZPC' DNA vaccine and analysis of its contraceptive potential. Biol. Reprod (2003) 68:1518-24.
    • (2003) Biol. Reprod. , vol.68 , pp. 1518-1524
    • Xiang, R.L.1    Zhou, F.2    Yang, Y.3    Peng, J.P.4
  • 112
    • 0035132541 scopus 로고    scopus 로고
    • Granulocyte/macrophage-colony stimulating factor produced by recombinant avian poxviruses enriches the regional lymph nodes with antigen-presenting cells and acts as an immunoadjuvant
    • KASS E, PANICALI DL, MAZZARA G, SCHLOM J, GREINER JW: Granulocyte/macrophage-colony stimulating factor produced by recombinant avian poxviruses enriches the regional lymph nodes with antigen-presenting cells and acts as an immunoadjuvant. Cancer Res. (2001) 61:206-214.
    • (2001) Cancer Res. , vol.61 , pp. 206-214
    • Kass, E.1    Panicali, D.L.2    Mazzara, G.3    Schlom, J.4    Greiner, J.W.5
  • 113
    • 0035154360 scopus 로고    scopus 로고
    • Expression of mouse interleukin-4 by a recombinant ectromelia virus suppresses cytolytic lymphocyte responses and overcomes genetic resistance to mousepox
    • JACKSON RJ, RAMSAYA J, CHRISTENSEN CD, BEATON S, HALL DF, RAMSHAW IA: Expression of mouse interleukin-4 by a recombinant ectromelia virus suppresses cytolytic lymphocyte responses and overcomes genetic resistance to mousepox. J. Virol. (2001) 75:1205-1210.
    • (2001) J. Virol. , vol.75 , pp. 1205-1210
    • Jackson, R.J.1    Ramsaya, J.2    Christensen, C.D.3    Beaton, S.4    Hall, D.F.5    Ramshaw, I.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.