Rat MDC family of proteins: Sequence analysis, tissue distribution, and expression in prepubertal and adult rat testis

Molecular Reproduction and Development

Volumn 48, Issue 2, 1997, Pages 159-167

  Frayne, Jan ^a   Jury, Jennifer A ^a   Barker, Helen L ^a   Hall, Len ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Disintegrin; Gene expression; Sperm antigens; Spermatogenesis

Indexed keywords

COMPLEMENTARY DNA; CYSTEINE; DISINTEGRIN; DNA; MEMBRANE PROTEIN; METALLOPROTEINASE; PROTEIN; RNA; SPERM ANTIGEN;

ANIMAL TISSUE; ARTICLE; DNA SEQUENCE; GENE EXPRESSION; MALE; MOLECULAR CLONING; NONHUMAN; POLYMERASE CHAIN REACTION; PREPUBERTY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPERMATOGENESIS; TESTIS; TISSUE DISTRIBUTION;

ADAM PROTEINS; AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; PROTEINS; RATS; SEQUENCE ANALYSIS, DNA; SEXUAL MATURATION; TESTIS;

ANIMALIA; MAMMALIA;

EID: 0030767188     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2795(199710)48:2<159::AID-MRD3>3.0.CO;2-R     Document Type: Article

References (24)

1. Almeida EAC, Huovilla APJ, Sutherland AE, Stephens LE, Calarco PG, Shaw LM, Mercurio AM, Sonnenberg A, Primakoff P, Myles DG, White JM (1995): Mouse egg integrin α6β1 functions as a sperm receptor. Cell 81:1095-1104.
2. Barker HL, Perry ACF, Jones R, Hall L (1994): Sequence and expression of a monkey testicular transcript encoding tMDC I, a novel member of the metalloproteinase-like, disintegrin-like, cysteine-rich (MDC) protein family. Bioch Biophys Acta 1218:429-131.
3. Blobel CP, Myles DG, Primakoff P, White JM (1990): Proteolytic processing of a protein involved in sperm-egg fusion correlates with acquisition of fertilization competence. J Cell Biol 111:69-78.
4. Blobel CP, Wolfsberg TG, Turck CW, Myles DG, Primakoff, P White JM (1992): A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion. Nature 356:248-252.
5. Carroll DJ, Dikegoros E, Koppel DE, Cowan AE (1995): Surface expression of the pre-β subunit of fertilin is regulated at a post-translational level in guinea pig spermatids. Dev Biol 168:429-437.
6. Fusi FM, Vignali M, Busacca M, Bronson RA (1992): Evidence for the presence of an integrin cell adhesion receptor on the oolemma of unfertilized human oocytes. Mol Reprod Devel 31:215-222.
7. Girotti M, Jones R, Emery DC, Chia W, Hall L (1992): Structure and expression of the rat epididymal secretory protein I gene. Biochem J 281:203-210.
8. Heinlein UAO, Wallat S, Senftleben A, Lemaire L (1994): Male germ cell-expressed mouse gene TAZ83 encodes a putative, cysteine rich transmembrane protein (cyritestin) sharing homologies with snake venom toxins and sperm egg fusion proteins. Dev Growth Differen 36:49-58.
9. Howard L, Lu X, Mitchell S, Griffiths S, Glynn P (1996): Molecular cloning of MADM: A catalytically active mammalian disintegrin-metalloprotease expressed in various cell types. Biochem J 317:45-50.
10. Jury JA, Frayne J, Hall L (1997): The human fertilin α gene is non-functional: Implications for its proposed role in fertilization. Biochem J 321:577-581.
11. Krätzschmar J, Lum L, Blobel CP (1996): Metargidin, a membrane-anchored metalloprotease-disintegrin protein with an RGD integrin binding sequence. J Biol Chem 271:4593-4596.
12. Leblond CP, Clermont Y (1952): Definition of the stages of the seminiferous epithelium in the rat. Ann NY Acad Sci 55:548-573.
13. Linder B, Bammer S, Heinlein UAO (1995): Delayed translation and posttranslational processing of cyritestin, an integral transmembrane protein of the mouse acrosome. Exp Cell Res 221:66-72.
14. Perry ACF, Jones R, Barker PJ, Hall L (1992): A mammalian epidiymal protein with remarkable sequence similarity to snake venom hemorrhagic peptides. Biochem J 286:671-675.
15. Perry ACF, Barker HL, Jones R, Hall L (1994): Genetic evidence for an additional member of the metalloproteinase-like, disintegrin-like. cysteine-rich (MDC) family of mammalian proteins and its abundant expession in the testis. Biochem Biophys Acta 1207:134-137.
16. Perry ACF, Gichuhi PM, Jones R, Hall L (1995a): Cloning and analysis of monkey fertilin reveals novel α subunit isoforms. Biochem J 307:843-850.
17. Perry ACF, Jones R, Hall L (1995b): Analysis of transcripts encoding novel members of the mammalian metalloprotease-like, disintegrin-like, cysteine-rich (MDC) protein family and their expression in reproductive and nonreproductive monkey tissues. Biochem J 312: 239-244.
18. Russell LD, Ettlin RA, Sinha Hikim AP, Clegg ED (1990): "Histological and Histopathological Evaluation of the Testis." Clearwater, FL: Cache River Press.
19. 1 is localised at specific sites of cell-to-cell contact in rat seminiferous epithelium. Biol Reprod 52:79-87.
20. Weskamp G, Kratzschmar J, Reid MS, Blobel CP (1996): MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains. J Cell Biol 132:717-726.
21. Wolfsberg TG, Bazan JF, Blobel CP, Myles DG, Primakoff P, White JM (1993): The precursor region of a protein active in sperm-egg fusion contains a metalloproteinase and a disintegrin domain: Structural, functional and evolutionary implications. Proc Natl Acad Sci USA 90:10783-10787.
22. Wolfsberg TG, Primakoff P, Myles DG, White JM (1995a): ADAM, a novel family of membrane proteins containing A Disintegrin and Metalloproteinase domain: Multipotential functions in cell-cell and cell-matrix interactions. J Cell Biol 131:275-278.
23. Wolfsberg TG, Straight PD, Gerena RL, Huovila A-PJ, Primakoff P, Myles DG, White JM (1995b): ADAM, a widely distributed and developmentally regulated gene family encoding membrane proteins with a disintegrin and metalloprotease domain. Dev Biol 169:378-383.
24. Yagami-Hiromasa T, Sato T, Kurisaki T, Kamijo K, Nabeshima Y-I, Fujisawa-Sehara A (1995): A metalloprotease-disintegrin participating in myoblast fusion. Nature 377:652-656.