Roles of the disintegrin domains of mouse fertilins α and β in fertilization

Biology of Reproduction

Volumn 59, Issue 1, 1998, Pages 145-152

  Evans, Janice P ^a,b   Schultz, Richard M ^a   Kopf, Gregory S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISINTEGRIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL ADHESION; EGG; FEMALE; FERTILIZATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; SPERM;

ADAM PROTEINS; ANIMALS; DIMERIZATION; DISINTEGRINS; FEMALE; FERTILIZATION IN VITRO; MALE; MEMBRANE GLYCOPROTEINS; METALLOENDOPEPTIDASES; MICE; OOCYTES; RECOMBINANT PROTEINS; SPERM-OVUM INTERACTIONS; STRUCTURE-ACTIVITY RELATIONSHIP; ZONA PELLUCIDA;

ANIMALIA;

EID: 0031778296     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod59.1.145     Document Type: Article

References (18)

1. Myles DG. Molecular mechanisms of sperm-egg membrane binding and fusion in mammals. Dev Biol 1993; 158:35-45.
2. Snell WJ, White JM. The molecules of mammalian fertilization. Cell 1996; 85:629-637.
3. Bigler D, Chen M, Waters S, White JM. A model for sperm-egg binding and fusion based on ADAMs and integrins. Trends Cell Biol 1997; 7:220-225.
4. Myles DG, Kimmel LH, Blobel CP, White JM, Primakoff P. Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion. Proc Natl Acad Sci USA 1994; 91:4195-4198.
5. 1 functions as a sperm receptor. Cell 1995; 81:1095-1104.
6. Evans JP, Schultz RM, Kopf GS. Mouse sperm-egg plasma membrane interactions: analysis of roles of egg integrins and the mouse sperm homologue of PH-30 (fertilin) β. J Cell Sci 1995; 108:3267-3278.
7. 1 integrin-mediated interaction. Dev Biol 1997; 187:79-93.
8. Evans JP, Schultz RM, Kopf GS. Characterization of the binding of recombinant mouse sperm fertilin α subunit to mouse eggs: evidence for function as a cell adhesion molecule in sperm-egg binding. Dev Biol 1997; 187:94-106.
9. Wolfsberg TG, Straight PD, Gerena RL, Huovila A-PJ, Primakoff P, Myles DG, White JM. ADAM, a widely distributed and developmentally regulated gene family encoding membrane proteins with A disintegrin and metalloprotease domain. Dev Biol 1995; 169:378-383.
10. Gichuchi PM, Ford WCL, Hall L. Evidence that peptides derived from the disintegrin domain of primate fertilin and containing the ECD motif block the binding of human spermatozoa to the zona-free hamster oocyte. Int J Androl 1997; 20:165-170.
11. Pyluck A, Yuan R, Galligan E Jr, Primakoff P, Myles DG, Sampson NS. ECD tripeptides inhibit in vitro fertilization in mice. Bioorg Med Chem Lett 1997; 7:1053-1058.
12. Yuan R, Primakoff P, Myles DG. A role for the disintegrin domain of cyritestin, a sperm surface protein belonging to the ADAM family, in mouse sperm-egg plasma membrane adhesion and fusion. J Cell Biol 1997; 137:105-112.
13. Blobel CP, Wolfsberg TG, Turck CW, Myles DG, Primakoff P, White JM. A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion. Nature 1992; 356:248-252.
14. Lum L, Blobel CP. Evidence for distinct serine protease activities with a potential role in processing the sperm protein fertilin. Dev Biol 1997; 191:131-135.
15. Waters SI, White JM. Biochemical and molecular characterization of bovine fertilin a and β (ADAM1 and ADAM2): a candidate spermegg binding/fusion complex. Biol Reprod 1997; 56:1245-1254.
16. Yanagimachi R. Mammalian fertilization. In: Knobil E, Neill JD (eds.), The Physiology of Reproduction. New York: Raven Press, Ltd.; 1994: 189-317.
17. Hardy CM, Clarke HG, Nixon B, Grigg JA, Hinds LA, Holland MK. Examination of the immunocontraceptive potential of recombinant rabbit fertilin subunits in rabbit. Biol Reprod 1997; 57:879-886.
18. Jury JA, Frayne J, Hall L. The human fertilin a gene is non-functional: implications for its proposed role in fertilization. Biochem J 1997; 321:577-581.