메뉴 건너뛰기




Volumn 43, Issue 3, 2001, Pages 135-142

Immunological factors governing resistance and susceptibility of mice to Leishmania major infection

Author keywords

Immune Response; Leishmania; Susceptibility to Leishmania; Th1; Th2 Paradigm

Indexed keywords

FAS ANTIGEN; FAS LIGAND; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; TRANSFORMING GROWTH FACTOR BETA;

EID: 0041859666     PISSN: 01874640     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (16)

References (132)
  • 2
    • 0029551775 scopus 로고    scopus 로고
    • Cutaneous leishmaniasis: A model for analysis of the immunoregulation by accessory cells
    • Moll, H., Ritter, U., Flohé, S., Erb, K., Bauer, S. and Blank, C. 1996. Cutaneous leishmaniasis: a model for analysis of the immunoregulation by accessory cells. Med. Microbiol. Immunol. 184:163.
    • (1996) Med. Microbiol. Immunol. , vol.184 , pp. 163
    • Moll, H.1    Ritter, U.2    Flohé, S.3    Erb, K.4    Bauer, S.5    Blank, C.6
  • 3
    • 0027473217 scopus 로고
    • Parasitism of epidermal Langerhans cells in experimental cutaneous leishmaniasis with Leishmania major
    • Blank, C., Fuchs, H., Rappersberger, K., Röllinghoff, M. and Moll, H. 1993. Parasitism of epidermal Langerhans cells in experimental cutaneous leishmaniasis with Leishmania major. J. Infect. Dis. 167:418.
    • (1993) J. Infect. Dis. , vol.167 , pp. 418
    • Blank, C.1    Fuchs, H.2    Rappersberger, K.3    Röllinghoff, M.4    Moll, H.5
  • 4
    • 0029993771 scopus 로고    scopus 로고
    • Murine epidermal Langerhans cells do not express inducible nitric oxide synthase
    • Blank, C., Bogdan, C., Bauer, C., Erb, K. and Moll, H. 1996. Murine epidermal Langerhans cells do not express inducible nitric oxide synthase. Eur. J. Immunol. 26:792.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 792
    • Blank, C.1    Bogdan, C.2    Bauer, C.3    Erb, K.4    Moll, H.5
  • 5
    • 0033178828 scopus 로고    scopus 로고
    • The role of dendritic cells in the induction and regulation of Immunity to microbial infection
    • Reis e Sousa, C., Sher, A. and Kaye, P. 1999. The role of dendritic cells in the induction and regulation of Immunity to microbial infection. Curr. Opin. Immunol. 11:392.
    • (1999) Curr. Opin. Immunol. , vol.11 , pp. 392
    • Reis e Sousa, C.1    Sher, A.2    Kaye, P.3
  • 6
    • 0033178708 scopus 로고    scopus 로고
    • Antigen presentation by macrophages harboring intravesicular pathogens
    • Overath, P. and Aebischer, T. 1999. Antigen presentation by macrophages harboring intravesicular pathogens. Parasitol. Today. 15:325.
    • (1999) Parasitol. Today. , vol.15 , pp. 325
    • Overath, P.1    Aebischer, T.2
  • 8
    • 0009020791 scopus 로고    scopus 로고
    • Ed. Ellipses AUPELF/UREF
    • Dedet, J. 1999. In: "Les leishmanioses. Ed. Ellipses AUPELF/UREF.
    • (1999) Les Leishmanioses
    • Dedet, J.1
  • 9
    • 0000669880 scopus 로고
    • Genetics of susceptibility and resistance in the vertebrate host
    • (W. Peters and R. Killick-Kendrick, ed). Academic Press, London
    • Bradley, D. J., 1987. Genetics of susceptibility and resistance in the vertebrate host. In «The leishmaniasis in Biology and Medicine» (W. Peters and R. Killick-Kendrick, ed). 2:551. Academic Press, London.
    • (1987) The Leishmaniasis in Biology and Medicine , vol.2 , pp. 551
    • Bradley, D.J.1
  • 10
    • 0029978520 scopus 로고    scopus 로고
    • Resistance to intracellular infection comparative genome analysis on NRAMP
    • Cellier, M., Belouchi, A. and Gros, P. 1996. Resistance to intracellular infection comparative genome analysis on NRAMP. Trends Genet. 12:201.
    • (1996) Trends Genet. , vol.12 , pp. 201
    • Cellier, M.1    Belouchi, A.2    Gros, P.3
  • 11
    • 0029978512 scopus 로고    scopus 로고
    • A yeast manganese transporter related to the macrophage protein involved in conferring resistance to mycobacteria
    • Supeck, F., Supekova, L., Nelson, H. and Nelson, N. 1996. A yeast manganese transporter related to the macrophage protein involved in conferring resistance to mycobacteria. Proc. Natl. Acad. Sci. USA. 93:5105.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5105
    • Supeck, F.1    Supekova, L.2    Nelson, H.3    Nelson, N.4
  • 12
    • 0033008432 scopus 로고    scopus 로고
    • Role of iron in Nramp 1-mediated inhibition of mycobacterial growth
    • Zwilling, B. S., Kuhn D. E., Wikoff, L., Brown, D. and Lafuse, W. 1999. Role of iron in Nramp 1-mediated inhibition of mycobacterial growth. Infect. Immunol. 67:1386.
    • (1999) Infect. Immunol. , vol.67 , pp. 1386
    • Zwilling, B.S.1    Kuhn, D.E.2    Wikoff, L.3    Brown, D.4    Lafuse, W.5
  • 13
    • 0020514042 scopus 로고
    • Leishmania donovani infection in heterozygous recombinant H-2 haplotype mice
    • Blackwell, J. M. Leishmania donovani infection in heterozygous and recombinant H-2 haplotype mice. Immunogenetics 1983;18:101.
    • (1983) Immunogenetics , vol.18 , pp. 101
    • Blackwell, J.M.1
  • 14
    • 0029739431 scopus 로고    scopus 로고
    • Mouse-Parasite interactions: From gene to population
    • Moulia, C., Le Brun, N. and Renaud, F. 1996. Mouse-Parasite interactions: from gene to population. Adv. Parasitol. 38:119.
    • (1996) Adv. Parasitol. , vol.38 , pp. 119
    • Moulia, C.1    Le Brun, N.2    Renaud, F.3
  • 15
    • 0024495092 scopus 로고
    • Influence of Lsh, H-2 and H-11-linked gene on visceralization and metastasis associated with Leishmania mexicana infection in mice
    • Roberts, M., Alexander, J. and Blackwell, J. M. 1989. Influence of Lsh, H-2 and H-11-linked gene on visceralization and metastasis associated with Leishmania mexicana infection in mice. Infect. Immunol. 57:875.
    • (1989) Infect. Immunol. , vol.57 , pp. 875
    • Roberts, M.1    Alexander, J.2    Blackwell, J.M.3
  • 16
    • 0030923103 scopus 로고    scopus 로고
    • Resistance to Leishmania major is linked to the H-2 region on chromosome 17 and to chromosome 9
    • Roberts, L. J., Baldwin, T. M., Curtis, J. M., Handman, E. and Foote, S. J. 1997. Resistance to Leishmania major is linked to the H-2 region on chromosome 17 and to chromosome 9. J. Exp. Med. 9:1705.
    • (1997) J. Exp. Med. , vol.9 , pp. 1705
    • Roberts, L.J.1    Baldwin, T.M.2    Curtis, J.M.3    Handman, E.4    Foote, S.J.5
  • 17
    • 0033391738 scopus 로고    scopus 로고
    • Chromosomes X, 9, and the H2 locus interact epistatically to control Leishmania major infection
    • Roberts L. J., Baldwin T. M., Speed T. P., Handman E., Foote S. J. 1999. Chromosomes X, 9, and the H2 locus interact epistatically to control Leishmania major infection. Eur. J. Immunol. 29:3047.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 3047
    • Roberts, L.J.1    Baldwin, T.M.2    Speed, T.P.3    Handman, E.4    Foote, S.J.5
  • 18
    • 0018745090 scopus 로고
    • Murine cutaneous leishmaniasis: Disease patterns in intact and nude mice of various genotypes and examination of some differences between normal and infected macrophages
    • Handman, E., Ceredig, R. and Mitchell, G. F. 1979. Murine cutaneous leishmaniasis: disease patterns in intact and nude mice of various genotypes and examination of some differences between normal and infected macrophages. J. Exp. Biol. Med. 57:9.
    • (1979) J. Exp. Biol. Med. , vol.57 , pp. 9
    • Handman, E.1    Ceredig, R.2    Mitchell, G.F.3
  • 19
    • 0021776325 scopus 로고
    • Genetic control of systemic Leishmania major infection: Identification of sublime differences for susceptibility to disease
    • Mock, B. A., Fortier, A. H., Potter, M., Blackwell, J. and Nacy, CA. 1985. Genetic control of systemic Leishmania major infection: identification of sublime differences for susceptibility to disease. Curr. Top. Microbiol. Immunol. 122:115.
    • (1985) Curr. Top. Microbiol. Immunol. , vol.122 , pp. 115
    • Mock, B.A.1    Fortier, A.H.2    Potter, M.3    Blackwell, J.4    Nacy, C.A.5
  • 20
    • 0027422394 scopus 로고
    • Genetic control of systemic Leishmania major infection in congenic, recombinant inbred and F2 population of mice
    • Mock, B., Blackwell, J., Hilgers, J., Potter, M. and Nacy, C.A. 1993. Genetic control of systemic Leishmania major infection in congenic, recombinant inbred and F2 population of mice. Eur. J. Immunogen. 20:335.
    • (1993) Eur. J. Immunogen. , vol.20 , pp. 335
    • Mock, B.1    Blackwell, J.2    Hilgers, J.3    Potter, M.4    Nacy, C.A.5
  • 21
    • 0042401532 scopus 로고
    • Different host genes recognise and control infection with taxonomically distinct Leishmania species
    • (J.A. Rioux, ed.). Louis-jean Imprimerie, Montpellier
    • Blackwell, J. M. and Alexander, J. 1986. Different host genes recognise and control infection with taxonomically distinct Leishmania species. In «Proceedings of an International Symposium on Taxonomy and Physiology of Leishmania» (J.A. Rioux, ed.). 211. Louis-jean Imprimerie, Montpellier.
    • (1986) Proceedings of an International Symposium on Taxonomy and Physiology of Leishmania , pp. 211
    • Blackwell, J.M.1    Alexander, J.2
  • 22
    • 0025302080 scopus 로고
    • Genetic analysis of Leishmania mexicana infection in mice: Single gene (Scl-2) controlled predisposition to cutaneous lesion development
    • Roberts, M., Alexander, J. and Blackwell, J. M. 1990. Genetic analysis of Leishmania mexicana infection in mice: single gene (Scl-2) controlled predisposition to cutaneous lesion development. J. Immunogen. 17:89.
    • (1990) J. Immunogen. , vol.17 , pp. 89
    • Roberts, M.1    Alexander, J.2    Blackwell, J.M.3
  • 23
    • 0023891323 scopus 로고
    • Sex differences and cross-immunity in DBA/2 mice infected with L. mexicana and L. major
    • Alexander, J. 1988. Sex differences and cross-immunity in DBA/2 mice infected with L. mexicana and L. major. Parasitology. 96:297.
    • (1988) Parasitology , vol.96 , pp. 297
    • Alexander, J.1
  • 25
    • 0019272612 scopus 로고
    • Genetic control of acquired resistance to visceral leishmaniasis in mice
    • DeTolla, L. J., Semprevivo, L. H., Polczuk, N. C. and Passmore, H. C. 1980. Genetic control of acquired resistance to visceral leishmaniasis in mice. Immunogenetics. 10:353.
    • (1980) Immunogenetics , vol.10 , pp. 353
    • DeTolla, L.J.1    Semprevivo, L.H.2    Polczuk, N.C.3    Passmore, H.C.4
  • 26
    • 0019788887 scopus 로고
    • Single gene control of resistance to cutaneous leishmaniasis in mice
    • DeTolla, L. J., Scott, P. A. and Farrell, J. P. Single gene control of resistance to cutaneous leishmaniasis in mice. Immunogenetics 1981;14:29.
    • (1981) Immunogenetics , vol.14 , pp. 29
    • DeTolla, L.J.1    Scott, P.A.2    Farrell, J.P.3
  • 27
    • 0041900142 scopus 로고
    • Studies of immune mechanisms in H-11-linked genetic susceptibility to murine visceral leishmaniasis
    • (D.T. Hart, ed), NATOASI series A. Plenum Press, New York
    • Roberts, M., Kaye, P. M., Milon, G. and Blackwell, J. M. 1988. Studies of immune mechanisms in H-11-linked genetic susceptibility to murine visceral leishmaniasis. IN "Leishmaniasis: The current status and new strategies for control" (D.T. Hart, ed), NATOASI series A. 163:259. Plenum Press, New York.
    • (1988) Leishmaniasis: The Current Status and New Strategies for Control , vol.163 , pp. 259
    • Roberts, M.1    Kaye, P.M.2    Milon, G.3    Blackwell, J.M.4
  • 28
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I: Definition according to profiles of lymphokines activities and secreted proteins
    • Mosmann, T. R., Cherwinski, I. I., Bond, M. W., Giedlin, M. A. and Coffman, R. L. 1986. Two types of murine helper T cell clone. I: Definition according to profiles of lymphokines activities and secreted proteins. J. Immunol. 136:2348.
    • (1986) J. Immunol. , vol.136 , pp. 2348
    • Mosmann, T.R.1    Cherwinski, I.I.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 29
    • 0024353079 scopus 로고
    • Th1 and Th2 cells: Different patterns of lymphokines secretion lead to different functional properties
    • Mosmann, T. R. and Coffman, R. L. 1989. Th1 and Th2 cells: different patterns of lymphokines secretion lead to different functional properties. Annu. Rev. Immunol. 7:145.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145
    • Mosmann, T.R.1    Coffman, R.L.2
  • 30
    • 0023492716 scopus 로고
    • Murine cutaneous leishmaniasis. Susceptibility correlates with differential expansion of helper T cell subsets
    • Locksley, R. M., Heinzel, F. P., Sadick, M. D., Holaday, B. J. and Gardner, K. D. 1987. Murine cutaneous leishmaniasis. Susceptibility correlates with differential expansion of helper T cell subsets Ann Inst Pasteur/Immunol. 138:744.
    • (1987) Ann. Inst. Pasteur/Immunol. , vol.138 , pp. 744
    • Locksley, R.M.1    Heinzel, F.P.2    Sadick, M.D.3    Holaday, B.J.4    Gardner, K.D.5
  • 31
    • 0024236111 scopus 로고
    • Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective Immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigen
    • Scott, P., Natovitz, P., Coffman, R. L., Pearce, E. and Sher, A. 1988. Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective Immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigen. J. Exp. Med. 168:1675.
    • (1988) J. Exp. Med. , vol.168 , pp. 1675
    • Scott, P.1    Natovitz, P.2    Coffman, R.L.3    Pearce, E.4    Sher, A.5
  • 32
    • 0025818157 scopus 로고
    • Helper T-cell subsets in mouse leishmaniasis: Induction, expansion and effector function
    • Locksley, R. M. and Scott, P. 1991. Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function. Immunol. Today. 12:A58.
    • (1991) Immunol. Today , vol.12
    • Locksley, R.M.1    Scott, P.2
  • 33
    • 0031568540 scopus 로고    scopus 로고
    • The mechanism of in vitro T helper cell type 1 to T helper cell type 2 switching in highly polarized Leishmania major-specific T cell populations
    • Mocci, S., Coffman, R. L. 1997. The mechanism of in vitro T helper cell type 1 to T helper cell type 2 switching in highly polarized Leishmania major-specific T cell populations. J. Immunol. 158:1559.
    • (1997) J. Immunol. , vol.158 , pp. 1559
    • Mocci, S.1    Coffman, R.L.2
  • 34
    • 0029892549 scopus 로고    scopus 로고
    • Genetic susceptibility to leishmanial infections: Studies in mice and man
    • Review
    • Blackwell, J. M. 1996. Genetic susceptibility to leishmanial infections: studies in mice and man. Parasitology. 112 Suppl:S67-74. Review.
    • (1996) Parasitology , vol.112 , Issue.SUPPL.
    • Blackwell, J.M.1
  • 35
    • 0025191159 scopus 로고
    • Activates macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism
    • Green, S. J., Meltzer, M. S., Hibbs, J. B. and Nacy, S. A. 1990. Activates macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism. J. Immunol. 144:278.
    • (1990) J. Immunol. , vol.144 , pp. 278
    • Green, S.J.1    Meltzer, M.S.2    Hibbs, J.B.3    Nacy, S.A.4
  • 37
    • 0028129526 scopus 로고
    • Tissue expression of inducible nitric oxide synthase is clossely associated with resistance to Leishmania major
    • Stenger, S., Thüring, H., Röllinghoff, M. and Bogdan, C. 1994. Tissue expression of inducible nitric oxide synthase is clossely associated with resistance to Leishmania major. J. Exp. Med. 180:783.
    • (1994) J. Exp. Med. , vol.180 , pp. 783
    • Stenger, S.1    Thüring, H.2    Röllinghoff, M.3    Bogdan, C.4
  • 38
    • 0029976423 scopus 로고    scopus 로고
    • Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase
    • Stenger, S., Donhauser, N., Thürin, H., Röllinghoff, M. and Bogdan, C. (1996). Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase. J. Exp. Med. 183:1501-1514.
    • (1996) J. Exp. Med. , vol.183 , pp. 1501-1514
    • Stenger, S.1    Donhauser, N.2    Thürin, H.3    Röllinghoff, M.4    Bogdan, C.5
  • 40
    • 0027248910 scopus 로고
    • Modulation of macrophage function by TGF-β, IL-4 and IL-10
    • Bogdan, C. and Nathan, C. 1993. Modulation of macrophage function by TGF-β, IL-4 and IL-10. Ann. N.Y. Acad. Sci. 685:713.
    • (1993) Ann. N.Y. Acad. Sci. , vol.685 , pp. 713
    • Bogdan, C.1    Nathan, C.2
  • 42
    • 0028326103 scopus 로고
    • CD4+ effector cells default to the Th2 pathway in interferon gamma-deficient mice infected with Leishmania major
    • Wang, Z. E., Reiner, S. L., Zheng, S., Dalton, D. K. and Locksley, R. M. 1994. CD4+ effector cells default to the Th2 pathway in interferon gamma-deficient mice infected with Leishmania major. J. Exp. Med. 179:1367.
    • (1994) J. Exp. Med. , vol.179 , pp. 1367
    • Wang, Z.E.1    Reiner, S.L.2    Zheng, S.3    Dalton, D.K.4    Locksley, R.M.5
  • 43
    • 0028963901 scopus 로고
    • Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper 1-type CD4+ T cell response
    • Swihart, K., Fruth, U., Messmer, N., Hug, K., Behin, R., Huang, S., Del Giudice, G., Aguet, M. and Louis, J. L. 1995. Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper 1-type CD4+ T cell response. J. Exp. Med. 181:961.
    • (1995) J. Exp. Med. , vol.181 , pp. 961
    • Swihart, K.1    Fruth, U.2    Messmer, N.3    Hug, K.4    Behin, R.5    Huang, S.6    Del Giudice, G.7    Aguet, M.8    Louis, J.L.9
  • 46
    • 0025661887 scopus 로고
    • Tumor necrosis factor (TNF-α) in leishmaniasis. II; TNF-α induced macrophage leishmanicidal activity is mediated by nitric oxide from L-arginine
    • Liew, F. Y., Li, Y. and Millot, S. 1990. Tumor necrosis factor (TNF-α) in leishmaniasis. II; TNF-α induced macrophage leishmanicidal activity is mediated by nitric oxide from L-arginine. Immunology 71:556.
    • (1990) Immunology , vol.71 , pp. 556
    • Liew, F.Y.1    Li, Y.2    Millot, S.3
  • 47
    • 0025847642 scopus 로고
    • Tumor necrosis factor-alpha: Central regulatory cytokine in the induction of macrophage antimicrobial activities
    • Nacy, C. A., Meierovics, A. I., Belosevic, M. and Green, S. J. 1991. Tumor necrosis factor-alpha: central regulatory cytokine in the induction of macrophage antimicrobial activities. Pathobiology. 59:182.
    • (1991) Pathobiology , vol.59 , pp. 182
    • Nacy, C.A.1    Meierovics, A.I.2    Belosevic, M.3    Green, S.J.4
  • 48
    • 0028273024 scopus 로고
    • Tumor necrosis factor alpha (TNF-alpha) and TNF-beta and their receptors in experimental cutaneous leishmaniasis
    • De Kossodo, S., Grau, G. E., Louis, J. A. and Muller I. 1994. Tumor necrosis factor alpha (TNF-alpha) and TNF-beta and their receptors in experimental cutaneous leishmaniasis. Infect. Immun. 62:1414.
    • (1994) Infect. Immun. , vol.62 , pp. 1414
    • De Kossodo, S.1    Grau, G.E.2    Louis, J.A.3    Muller, I.4
  • 49
    • 0027202137 scopus 로고
    • IL-7 enhances antimicrobial activity against Leishmania major in murine macrophages
    • Gessner, A., Vieth, M, Will, A., Schröppel, K. and Röllinghoff M. 1993. IL-7 enhances antimicrobial activity against Leishmania major in murine macrophages. Infect. Immun. 61:4008.
    • (1993) Infect. Immun. , vol.61 , pp. 4008
    • Gessner, A.1    Vieth, M.2    Will, A.3    Schröppel, K.4    Röllinghoff, M.5
  • 50
    • 0029982872 scopus 로고    scopus 로고
    • Mice lacking the TNF receptor p55 fait to resolve lesion caused by infection with Leishmania major, but control parasite replication
    • Vieira, L. Q., Goldschmidt, M., Nashleanas, M., Pfeiffer, K., Marck, T. and Scott, P. 1996. Mice lacking the TNF receptor p55 fait to resolve lesion caused by infection with Leishmania major, but control parasite replication. J. Immunol. 157:827.
    • (1996) J. Immunol. , vol.157 , pp. 827
    • Vieira, L.Q.1    Goldschmidt, M.2    Nashleanas, M.3    Pfeiffer, K.4    Marck, T.5    Scott, P.6
  • 52
    • 0031739697 scopus 로고    scopus 로고
    • CTLA4 (CD152) modulates the Th subset response and alters the course of experimental Leishmania major infection
    • Saha, B., Chattopadhyay, S., Germond, R., Harlan, D. M., Perrin, P. J. 1998. CTLA4 (CD152) modulates the Th subset response and alters the course of experimental Leishmania major infection. Eur. J. Immunol. 28:4213.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 4213
    • Saha, B.1    Chattopadhyay, S.2    Germond, R.3    Harlan, D.M.4    Perrin, P.J.5
  • 53
    • 0033153218 scopus 로고    scopus 로고
    • Expression and contribution of B7-1 (CD80) and B7-2 (CD86) in the early immune response to Leishmania major infection
    • Elloso, M. M. and Scott, P. 1999. Expression and contribution of B7-1 (CD80) and B7-2 (CD86) in the early immune response to Leishmania major infection. J. Immunol. 162:6708.
    • (1999) J. Immunol. , vol.162 , pp. 6708
    • Elloso, M.M.1    Scott, P.2
  • 54
    • 0027255488 scopus 로고
    • Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice
    • Scharton, T. M. and Scott, P. 1993. Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice. J. Exp. Med. 178:567-577.
    • (1993) J. Exp. Med. , vol.178 , pp. 567-577
    • Scharton, T.M.1    Scott, P.2
  • 55
    • 0029166460 scopus 로고
    • Early parasite containment is decisive for resistance to Leishmania major infection
    • Laskay, T., Röllinghoff, M. and Solbach, W. 1995. Early parasite containment is decisive for resistance to Leishmania major infection. Eur. J. Immunol. 25:2220-2227.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 2220-2227
    • Laskay, T.1    Röllinghoff, M.2    Solbach, W.3
  • 56
    • 0033153483 scopus 로고    scopus 로고
    • Mice lacking NK cells develop an efficient Th1 response and control cutaneous Leishmania major infection
    • Satoskar, A. R., Stamm, L. M., Zhang, X., Satoskar, A. A., Okano, M., Terhorst, C., David, J. R. and Wang, B. 1999. Mice lacking NK cells develop an efficient Th1 response and control cutaneous Leishmania major infection. J. Immunol. 162:6747-6754.
    • (1999) J. Immunol. , vol.162 , pp. 6747-6754
    • Satoskar, A.R.1    Stamm, L.M.2    Zhang, X.3    Satoskar, A.A.4    Okano, M.5    Terhorst, C.6    David, J.R.7    Wang, B.8
  • 57
    • 0029076809 scopus 로고
    • Endogenous IL-12 is required for control of Th2 cytokine responses capable of exacerbating leishmaniasis in normal resistance mice
    • Heinzel, F. P., Rerko, R. M., Ahmed, F. and Pearlment, E. 1995. Endogenous IL-12 is required for control of Th2 cytokine responses capable of exacerbating leishmaniasis in normal resistance mice. J. Immunol. 155:730-739.
    • (1995) J. Immunol. , vol.155 , pp. 730-739
    • Heinzel, F.P.1    Rerko, R.M.2    Ahmed, F.3    Pearlment, E.4
  • 58
    • 0030002111 scopus 로고    scopus 로고
    • Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response
    • Mattner, F., Magram, J., Ferrante, J., Lanouis, P., DiPadova, K., Behin, R., Gately, M. K., Louis, J. A. and Alber, G. 1996. Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur. J. Immunol. 26:1553-1559.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1553-1559
    • Mattner, F.1    Magram, J.2    Ferrante, J.3    Lanouis, P.4    DiPadova, K.5    Behin, R.6    Gately, M.K.7    Louis, J.A.8    Alber, G.9
  • 59
    • 0034661678 scopus 로고    scopus 로고
    • IL-12 required to maintain a Th1 response during Leishmania major infection
    • Park, A. Y., Hondowicz, B. D. and Scott, P. 2000. IL-12 required to maintain a Th1 response during Leishmania major infection. J. Immunol. 165:896-902.
    • (2000) J. Immunol. , vol.165 , pp. 896-902
    • Park, A.Y.1    Hondowicz, B.D.2    Scott, P.3
  • 60
    • 0028158318 scopus 로고
    • Leishmania promastigotes evade interleukin 12 (IL-12). Induction by macrophage and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection
    • Reiner, S. L., Zheng, S., Wang, Z. E., Stowring, L. and Locksley, R. M. 1994. Leishmania promastigotes evade interleukin 12 (IL-12). induction by macrophage and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection. J. Exp. Med. 179:447-456.
    • (1994) J. Exp. Med. , vol.179 , pp. 447-456
    • Reiner, S.L.1    Zheng, S.2    Wang, Z.E.3    Stowring, L.4    Locksley, R.M.5
  • 61
    • 0003137908 scopus 로고    scopus 로고
    • Immunomodulatory functions and molecular regulation of IL-12
    • ed L. Adorini, Milan
    • Xiaojing, M., Aste-Amezaga, M., Gri, G., Gerosa, F., Trinchieri, G. 1997. Immunomodulatory functions and molecular regulation of IL-12. In "IL-12"; ed L. Adorini, Milan, pp 1-22.
    • (1997) IL-12 , pp. 1-22
    • Xiaojing, M.1    Aste-Amezaga, M.2    Gri, G.3    Gerosa, F.4    Trinchieri, G.5
  • 62
    • 0028929566 scopus 로고
    • A recombinant Leishmania antigen that stimulates human peripheral blood mononuclear cells to express a Th1-type cytokine profile and to produce IL-12
    • Skeiki, Y. A. W., Guderian, J. A., Benson, D. R., Bacelar, O., Carvalho, E. M., Kubin, M., Badaro, R., Trinchieri, G., and Reed, G. 1995. A recombinant Leishmania antigen that stimulates human peripheral blood mononuclear cells to express a Th1-type cytokine profile and to produce IL-12. J. Exp. Med. 181:1527-1537.
    • (1995) J. Exp. Med. , vol.181 , pp. 1527-1537
    • Skeiki, Y.A.W.1    Guderian, J.A.2    Benson, D.R.3    Bacelar, O.4    Carvalho, E.M.5    Kubin, M.6    Badaro, R.7    Trinchieri, G.8    Reed, G.9
  • 64
    • 0033179608 scopus 로고    scopus 로고
    • Receptor mediated subversion of macrophage cytokine production by intracellular pathogens
    • Mosser, D. and Karp, Ch. 1999. Receptor mediated subversion of macrophage cytokine production by intracellular pathogens. Curr. Opin. Immunol. 11:406-411.
    • (1999) Curr. Opin. Immunol. , vol.11 , pp. 406-411
    • Mosser, D.1    Karp, Ch.2
  • 65
    • 0030021084 scopus 로고    scopus 로고
    • Leishmania promastigotes inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice
    • Carrera, L., Gazzinelli, R. T., Badolato, R., Hieny, S., Müller, W., Kühn, R. and Sacks, D. L. 1996. Leishmania promastigotes inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice. J. Exp. Med. 183:515-526.
    • (1996) J. Exp. Med. , vol.183 , pp. 515-526
    • Carrera, L.1    Gazzinelli, R.T.2    Badolato, R.3    Hieny, S.4    Müller, W.5    Kühn, R.6    Sacks, D.L.7
  • 66
    • 0030980385 scopus 로고    scopus 로고
    • Regulation of interleukin-12 by complement receptor 3 signaling
    • Marth, T. and Kelsall, B. L. 1997. Regulation of interleukin-12 by complement receptor 3 signaling. J. Exp. Med. 185:1987-1985.
    • (1997) J. Exp. Med. , vol.185 , pp. 1987-1985
    • Marth, T.1    Kelsall, B.L.2
  • 67
    • 0030926583 scopus 로고    scopus 로고
    • Selective suppression of interleukin-12 induction after macrophages receptor ligation
    • Sutterwala, F. S. Noel, G. J., Glynes, R. and Mosser, D. M. 1997. Selective suppression of interleukin-12 induction after macrophages receptor ligation; J. Exp. Med. 185:1977-1985.
    • (1997) J. Exp. Med. , vol.185 , pp. 1977-1985
    • Sutterwala, F.S.1    Noel, G.J.2    Glynes, R.3    Mosser, D.M.4
  • 69
    • 0029077326 scopus 로고
    • IL-12 is required for natural killer cell activation and subsequent T helper I cell development in experimental leishmaniasis
    • Scharton-Kersten, T., Afonso, L. C., Wysocka, M., Trinchieri, G. and Scott, P. 1995. IL-12 is required for natural killer cell activation and subsequent T helper I cell development in experimental leishmaniasis. J. Immunol 154:5320-5330.
    • (1995) J. Immunol. , vol.154 , pp. 5320-5330
    • Scharton-Kersten, T.1    Afonso, L.C.2    Wysocka, M.3    Trinchieri, G.4    Scott, P.5
  • 70
    • 0031739890 scopus 로고    scopus 로고
    • Antigen-pulsed epidermal Langerhans cells protect susceptible mice from infection with the intracellular parasite Leishmania major
    • Flohe, S. B., Bauer, C., Flohe, S., Moll, H. 1998. Antigen-pulsed epidermal Langerhans cells protect susceptible mice from infection with the intracellular parasite Leishmania major. Eur. J. Immunol. 28:3800-3811.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 3800-3811
    • Flohe, S.B.1    Bauer, C.2    Flohe, S.3    Moll, H.4
  • 72
    • 0029933509 scopus 로고    scopus 로고
    • Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated Immunity
    • Kamanaka, M., Yu, P., Yasui, T., Yoshida, K., Kawabe, T., Horii, T., Kishimoto, T., and Kikutani, H. 1996. Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated Immunity. Immunity 4:275-281.
    • (1996) Immunity , vol.4 , pp. 275-281
    • Kamanaka, M.1    Yu, P.2    Yasui, T.3    Yoshida, K.4    Kawabe, T.5    Horii, T.6    Kishimoto, T.7    Kikutani, H.8
  • 74
    • 0029925517 scopus 로고    scopus 로고
    • Disruption of CD40-CD40 ligand interaction results in enhanced susceptible to Leishmania amazonensis infection
    • Soong, L., Xu, J., Grewa, L. I. S., Kima, P., Sun, J., Longley B.J., Ruddle, N., McMahon-Prat, D., and Flavel, R.A. 1996. Disruption of CD40-CD40 ligand interaction results in enhanced susceptible to Leishmania amazonensis infection. Immunity 4:263-273.
    • (1996) Immunity , vol.4 , pp. 263-273
    • Soong, L.1    Xu, J.2    Grewa, L.I.S.3    Kima, P.4    Sun, J.5    Longley, B.J.6    Ruddle, N.7    McMahon-Prat, D.8    Flavel, R.A.9
  • 75
    • 0033532294 scopus 로고    scopus 로고
    • Requirement for type 2 NO synthase for IL-12 signaling in innate immunity
    • Diefenbach, A., Schindler, H., Rollinhoff, M., Yokoyama, W.M., Bogdan, C. 1999. Requirement for type 2 NO synthase for IL-12 signaling in innate immunity. Science 7;284(5416):951.
    • (1999) Science , vol.284 , Issue.5416 , pp. 951
    • Diefenbach, A.1    Schindler, H.2    Rollinhoff, M.3    Yokoyama, W.M.4    Bogdan, C.5
  • 76
    • 0028990677 scopus 로고
    • Fas-mediated cytotoxicity; a new immunoregulatory and pathogenic function of Th1 CD4+ T cells
    • Yagita, H., Hanabuchi, S. Asano, Y., Tamura, T., Nariuchi, H. and Okumura, K. 1995. Fas-mediated cytotoxicity; a new immunoregulatory and pathogenic function of Th1 CD4+ T cells. Immunol. Rev 146:223-239.
    • (1995) Immunol. Rev. , vol.146 , pp. 223-239
    • Yagita, H.1    Hanabuchi, S.2    Asano, Y.3    Tamura, T.4    Nariuchi, H.5    Okumura, K.6
  • 77
    • 2642613665 scopus 로고    scopus 로고
    • The resolution of lesions induced by Leishmania major in mice requires a functional Fas (APO-1, CD95) pathway of cytotoxicity
    • Conceicao-Silva F., Hahne M., Schroter M., Louis J. and Tschopp J. 1998. The resolution of lesions induced by Leishmania major in mice requires a functional Fas (APO-1, CD95) pathway of cytotoxicity. Eur. J. Immunol. 28:237-245.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 237-245
    • Conceicao-Silva, F.1    Hahne, M.2    Schroter, M.3    Louis, J.4    Tschopp, J.5
  • 78
    • 0032063360 scopus 로고    scopus 로고
    • Mice defective in Fas are highly susceptible to Leishmania major infection despite elevated IL-12 synthesis, strong Th1 responses, and enhanced nitric oxide production
    • Huang, F. P., Xu, D., Esfandiari, E. O., Sands, W., Wei, X. Q., Liew, F. Y. 1998. Mice defective in Fas are highly susceptible to Leishmania major infection despite elevated IL-12 synthesis, strong Th1 responses, and enhanced nitric oxide production. J. Immunol. 160:4143-4147.
    • (1998) J. Immunol. , vol.160 , pp. 4143-4147
    • Huang, F.P.1    Xu, D.2    Esfandiari, E.O.3    Sands, W.4    Wei, X.Q.5    Liew, F.Y.6
  • 79
    • 0344327067 scopus 로고    scopus 로고
    • Early gene expression of NK cell-activating chemokines in mice resistant to Leishmania major
    • Vester, B., Muller, K., Solbach, W. and Laskay, T. 1999. Early gene expression of NK cell-activating chemokines in mice resistant to Leishmania major. Infect. Immun. 67:3155-3159.
    • (1999) Infect. Immun. , vol.67 , pp. 3155-3159
    • Vester, B.1    Muller, K.2    Solbach, W.3    Laskay, T.4
  • 80
    • 0027469844 scopus 로고
    • T cell response in murine Leishmania mexicana amazonensis infection: Production of IFN-γ by CD8+ cell
    • Chan, M. M. (1993). T cell response in murine Leishmania mexicana amazonensis infection: production of IFN-γ by CD8+ cell. Eur. J. Immunol. 23:1181-1184.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1181-1184
    • Chan, M.M.1
  • 81
    • 0027254943 scopus 로고
    • Course of Leishmania infection in β2-microglobulin-deficient mice
    • Overath, P. and Harbecke, D. 1993. Course of Leishmania infection in β2-microglobulin-deficient mice. Immunol. Lett. 37:13-17.
    • (1993) Immunol. Lett. , vol.37 , pp. 13-17
    • Overath, P.1    Harbecke, D.2
  • 82
    • 0027200941 scopus 로고
    • Targeted activation of CD8 cells and infection of β2-microglobulin deficient mice fail to confirm a primary protective role for CD8 cells in experimental leishmaniasis
    • Wang, Z. E., Reiner, S. L., Hatam, F., Heinzel, F. P., Bouvier, J., Turck, C. W. and Locksley, R. M. 1993. Targeted activation of CD8 cells and infection of β2-microglobulin deficient mice fail to confirm a primary protective role for CD8 cells in experimental leishmaniasis. J. Immunol. 151:2077-2086.
    • (1993) J. Immunol. , vol.151 , pp. 2077-2086
    • Wang, Z.E.1    Reiner, S.L.2    Hatam, F.3    Heinzel, F.P.4    Bouvier, J.5    Turck, C.W.6    Locksley, R.M.7
  • 83
    • 0031793544 scopus 로고    scopus 로고
    • The biogenesis and properties of the parasitophorous vacuoles that harbor Leishmania in murine macrophages
    • Antoine, J. C., Prina, E., Lang, T. and Courret, N. 1998. The biogenesis and properties of the parasitophorous vacuoles that harbor Leishmania in murine macrophages. Trends. Microbiol. 7:392-401.
    • (1998) Trends. Microbiol. , vol.7 , pp. 392-401
    • Antoine, J.C.1    Prina, E.2    Lang, T.3    Courret, N.4
  • 84
    • 0027304337 scopus 로고
    • Immunology of leishmaniasis
    • Liew, F. Y. and O'Donnell, C. A. 1993. Immunology of leishmaniasis. Adv. Parasitol. 32:162-192.
    • (1993) Adv. Parasitol. , vol.32 , pp. 162-192
    • Liew, F.Y.1    O'Donnell, C.A.2
  • 85
    • 0028933795 scopus 로고
    • The regulation of Immunity Leishmania major
    • Reiner, S. L. and Locksley, R. M. 1995. The regulation of Immunity Leishmania major. Annu. Rev. Immunol. 13:151-177.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 151-177
    • Reiner, S.L.1    Locksley, R.M.2
  • 86
    • 0025133974 scopus 로고
    • Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism
    • Sadick, M. D., Heinzel, F. P., Holaday, B. J., Pu, R. T., Dawkins, R. S., Locksley, R. M. 1990. Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism. J. Exp. Med. 171:115-27.
    • (1990) J. Exp. Med. , vol.171 , pp. 115-127
    • Sadick, M.D.1    Heinzel, F.P.2    Holaday, B.J.3    Pu, R.T.4    Dawkins, R.S.5    Locksley, R.M.6
  • 87
    • 0026500979 scopus 로고
    • IL-4 induces a Th2 response to Leishmania major-infected mice
    • Chatelain, R., Varkila, K. and Coffman, R. L. 1992. IL-4 induces a Th2 response to Leishmania major-infected mice. J. Immunol. 148:1182-1187.
    • (1992) J. Immunol. , vol.148 , pp. 1182-1187
    • Chatelain, R.1    Varkila, K.2    Coffman, R.L.3
  • 88
    • 0028048136 scopus 로고
    • Recombinant soluble IL-4 receptor acts as an antagonist of IL-4 in murine cutaneous leishmaniasis
    • Gessner, A., Schröppel, K., Will, A., Enssler, K. H., Lauffer, L. and Röllinghoff, M. 1994. Recombinant soluble IL-4 receptor acts as an antagonist of IL-4 in murine cutaneous leishmaniasis. Infect. Immun. 62:4112-4117.
    • (1994) Infect. Immun. , vol.62 , pp. 4112-4117
    • Gessner, A.1    Schröppel, K.2    Will, A.3    Enssler, K.H.4    Lauffer, L.5    Röllinghoff, M.6
  • 89
    • 0027472336 scopus 로고
    • Interleukin-4 transgenic mice of resistant background are susceptible to Leishmania major infection
    • Leal, L. M., Moss, C. C., Kuhn, D. W., Muller, R. and Liew, F. Y. 1993. Interleukin-4 transgenic mice of resistant background are susceptible to Leishmania major infection. Eur. J. Immunol. 23:566-569.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 566-569
    • Leal, L.M.1    Moss, C.C.2    Kuhn, D.W.3    Muller, R.4    Liew, F.Y.5
  • 90
    • 0345222527 scopus 로고    scopus 로고
    • A single intramuscular injection with an adenovirus-expressing IL-12 protects BALB/c mice against Leishmania major infection, while treatment with an IL-4-expressing vector increases disease susceptibility in B10.D2 mice
    • Gabaglia C. R., Pedersen B., Hitt, M., Burdin, N., Sercarz, E. E., Graham, F. L., Gauldie, J., Braciak, T. A. 1999. A single intramuscular injection with an adenovirus-expressing IL-12 protects BALB/c mice against Leishmania major infection, while treatment with an IL-4-expressing vector increases disease susceptibility in B10.D2 mice. J. Immunol. 162:753-760.
    • (1999) J. Immunol. , vol.162 , pp. 753-760
    • Gabaglia, C.R.1    Pedersen, B.2    Hitt, M.3    Burdin, N.4    Sercarz, E.E.5    Graham, F.L.6    Gauldie, J.7    Braciak, T.A.8
  • 91
    • 85011253368 scopus 로고    scopus 로고
    • The fate and persistence of Leishmania major in mice of different genetic backgrounds: An example of exploitation of the immune system by intracellular parasites
    • Launois, P., Louis J. A., Milon G. 1997. The fate and persistence of Leishmania major in mice of different genetic backgrounds: an example of exploitation of the immune system by intracellular parasites. Parasitology 115 Suppl:S25-32.
    • (1997) Parasitology , vol.115 , Issue.SUPPL.
    • Launois, P.1    Louis, J.A.2    Milon, G.3
  • 92
    • 0032403583 scopus 로고    scopus 로고
    • The IL-4 rapidly produced in BALB/c mice after infection with Leishmania major down-regulates IL-12 receptor beta 2-chain expression on CD4+ T cells resulting in a state of unresponsiveness to IL-12
    • Himmelrich, H., Parra-Lopez, C., Tacchini-Cottier, F., Louis, J. A., Launois, P. 1998. The IL-4 rapidly produced in BALB/c mice after infection with Leishmania major down-regulates IL-12 receptor beta 2-chain expression on CD4+ T cells resulting in a state of unresponsiveness to IL-12. J. Immunol. 161:6156-6163.
    • (1998) J. Immunol. , vol.161 , pp. 6156-6163
    • Himmelrich, H.1    Parra-Lopez, C.2    Tacchini-Cottier, F.3    Louis, J.A.4    Launois, P.5
  • 93
    • 0027485741 scopus 로고
    • Mapping of genes controlling Leishmania major infection in CXS recombinant inbred mice
    • Roberts, M., Mock, B. A., Blackwell, J. M. 1993. Mapping of genes controlling Leishmania major infection in CXS recombinant inbred mice. Eur. J. Immunogen. 20:349-362.
    • (1993) Eur. J. Immunogen. , vol.20 , pp. 349-362
    • Roberts, M.1    Mock, B.A.2    Blackwell, J.M.3
  • 96
    • 0029584457 scopus 로고
    • In susceptible mice. Leishmania major induce very rapid interleukin-4 production by CD4+ T cells which are NK1.1-
    • Launois, P., Otheki, T., Swihart, K., MacDonald, H. R. and Louis, J. A. 1995. In susceptible mice, Leishmania major induce very rapid interleukin-4 production by CD4+ T cells which are NK1.1-. Eur. J. Immunol. 25:3298-3307.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3298-3307
    • Launois, P.1    Otheki, T.2    Swihart, K.3    MacDonald, H.R.4    Louis, J.A.5
  • 97
    • 0030588715 scopus 로고    scopus 로고
    • Early production of IL-4 and induction of Th2 responses in the lymph node originate from an MHC class 1-independent CD4+NK1.1- T cell population
    • von der Weid, T., Beebe, A. M., Roopenian, D. C., Coffman, R. L. 1996. Early production of IL-4 and induction of Th2 responses in the lymph node originate from an MHC class 1-independent CD4+NK1.1- T cell population. J. Immunol. 157:4421-7.
    • (1996) J. Immunol. , vol.157 , pp. 4421-4427
    • Von der Weid, T.1    Beebe, A.M.2    Roopenian, D.C.3    Coffman, R.L.4
  • 100
    • 0029849205 scopus 로고    scopus 로고
    • Resistance to Leishmania major induced by tolerance to a single antigen
    • Julia, V., Rassoulzadegan, M. and Glaichenhaus, N. 1996. Resistance to Leishmania major induced by tolerance to a single antigen. Science 274:421.
    • (1996) Science , vol.274 , pp. 421
    • Julia, V.1    Rassoulzadegan, M.2    Glaichenhaus, N.3
  • 101
    • 0027339408 scopus 로고
    • Th1 and Th2 cell antigen receptors in experimental leishmaniasis
    • Reiner, S. L., Wang, Z. E., Hatam, F., Scott, P. and Locksley, R. M. 1993. Th1 and Th2 cell antigen receptors in experimental leishmaniasis. Science 259:147.
    • (1993) Science , vol.259 , pp. 147
    • Reiner, S.L.1    Wang, Z.E.2    Hatam, F.3    Scott, P.4    Locksley, R.M.5
  • 102
    • 0034193027 scopus 로고    scopus 로고
    • In BALB/c mice, IL-4 production during the initial phase of infection with Leishmania major is necessary and sufficient to instruct Th2 cell development resulting in progressive disease
    • Himmelrich, H., Pascal, L., Maillard, I., Biedermann, T., Tacchini-Cottier, F., Locksley, R., Röcken, M. and Louis, J. 2000. In BALB/c mice, IL-4 production during the initial phase of infection with Leishmania major is necessary and sufficient to instruct Th2 cell development resulting in progressive disease. J. Immunol. 164:4819.
    • (2000) J. Immunol. , vol.164 , pp. 4819
    • Himmelrich, H.1    Pascal, L.2    Maillard, I.3    Biedermann, T.4    Tacchini-Cottier, F.5    Locksley, R.6    Röcken, M.7    Louis, J.8
  • 103
    • 0034670017 scopus 로고    scopus 로고
    • Priming by microbial antigens from the intestinal flora determines the ability of CD4+ T cells to rapidly secrete IL-4 in BALB/c mice infected with Leishmania major
    • Julia, V., McSorley, S. S., Malherbe, L., Breittmayer, J. P., Girard-Pipau, F., Beck, A. and Glaichenhaus, N. 2000. Priming by microbial antigens from the intestinal flora determines the ability of CD4+ T cells to rapidly secrete IL-4 in BALB/c mice infected with Leishmania major. J. Immunol. 165:5637.
    • (2000) J. Immunol. , vol.165 , pp. 5637
    • Julia, V.1    McSorley, S.S.2    Malherbe, L.3    Breittmayer, J.P.4    Girard-Pipau, F.5    Beck, A.6    Glaichenhaus, N.7
  • 104
    • 0035168492 scopus 로고    scopus 로고
    • T-cell responses to immunodominant LACK antigen do not play a critical role in determining susceptibility of BALB/c mice to Leishmania mexicana
    • Aguilar-Torrentera, F., Glaichenhaus, N., Laman, J. and Carlier, Y. 2001. T-cell responses to immunodominant LACK antigen do not play a critical role in determining susceptibility of BALB/c mice to Leishmania mexicana. Infect. Immun. 69:617.
    • (2001) Infect. Immun. , vol.69 , pp. 617
    • Aguilar-Torrentera, F.1    Glaichenhaus, N.2    Laman, J.3    Carlier, Y.4
  • 105
    • 0030023112 scopus 로고    scopus 로고
    • Susceptibility to Leishmania major infection in the IL-4 deficient mice
    • Noben-Trauth, N., Kropf, P. and Muller, I. 1996. Susceptibility to Leishmania major infection in the IL-4 deficient mice. Science 271:987.
    • (1996) Science , vol.271 , pp. 987
    • Noben-Trauth, N.1    Kropf, P.2    Muller, I.3
  • 106
    • 0033563135 scopus 로고    scopus 로고
    • IL-4 and IL-4 receptor-deficient BALB/c mice reveal differences in susceptibility to L. major parasite substrain
    • Noben-Trauth, N., Paul, W.E. and Sacks, D. 1999. IL-4 and IL-4 receptor-deficient BALB/c mice reveal differences in susceptibility to L. major parasite substrain. J. Immunol. 162:6132.
    • (1999) J. Immunol. , vol.162 , pp. 6132
    • Noben-Trauth, N.1    Paul, W.E.2    Sacks, D.3
  • 107
    • 0030298147 scopus 로고    scopus 로고
    • Early IL-4 production does not predict susceptibility to Leishmania major
    • Scott, P., Eaton, A., Gause, W. C., di Zhou, X., Hondowicz, B., 1996. Early IL-4 production does not predict susceptibility to Leishmania major. Exp. Parasitol. 84:178.
    • (1996) Exp. Parasitol. , vol.84 , pp. 178
    • Scott, P.1    Eaton, A.2    Gause, W.C.3    Di Zhou, X.4    Hondowicz, B.5
  • 108
    • 0033566955 scopus 로고    scopus 로고
    • BCL-6-deficient mice reveal an IL-4-independent, STAT6-dependent pathway that controls susceptibility to infection by Leishmania major
    • Dent, A. L., Doherty, T. M., Paul, W. E., Sher, A. and Staudt, L. M. 1999. BCL-6-deficient mice reveal an IL-4-independent, STAT6-dependent pathway that controls susceptibility to infection by Leishmania major. J. Immunol. 163:2098.
    • (1999) J. Immunol. , vol.163 , pp. 2098
    • Dent, A.L.1    Doherty, T.M.2    Paul, W.E.3    Sher, A.4    Staudt, L.M.5
  • 109
    • 0028299420 scopus 로고
    • Interleukin 13 elicits a subset of the activities of its close relative IL-4
    • Zurawski, G. and de Vries, J. E. 1994. Interleukin 13 elicits a subset of the activities of its close relative IL-4. Stem Cells. 12:169.
    • (1994) Stem Cells , vol.12 , pp. 169
    • Zurawski, G.1    De Vries, J.E.2
  • 111
    • 0030587813 scopus 로고    scopus 로고
    • Impaired IL-13-mediated functions of macrophages in STAT6-deficient mice
    • Takeda, K., Kamanaka, T., Tanaka, T., Kishimoto, T. and Aklra, S. 1996. Impaired IL-13-mediated functions of macrophages in STAT6-deficient mice. J. Immunol. 157:3220-3222.
    • (1996) J. Immunol. , vol.157 , pp. 3220-3222
    • Takeda, K.1    Kamanaka, T.2    Tanaka, T.3    Kishimoto, T.4    Aklra, S.5
  • 113
    • 0031665968 scopus 로고    scopus 로고
    • Increased capacity for IL-2 synthesis parallels disease progression in mice infected with Leishmania major
    • Heinzel, F. P., Rerko, R. M., Hujer, A. M. and Maier, R. A. 1998. Increased capacity for IL-2 synthesis parallels disease progression in mice infected with Leishmania major. Infect. Immun. 66:4537.
    • (1998) Infect. Immun. , vol.66 , pp. 4537
    • Heinzel, F.P.1    Rerko, R.M.2    Hujer, A.M.3    Maier, R.A.4
  • 114
    • 0027158442 scopus 로고
    • IL-2 is necessary for the progression of leishmaniasis in susceptible murine hosts
    • Heinzel, F. P., Rerko, R. M., Hata, M. and Locksley, R. M. 1993. IL-2 is necessary for the progression of leishmaniasis in susceptible murine hosts. J. Immunol. 150:3924.
    • (1993) J. Immunol. , vol.150 , pp. 3924
    • Heinzel, F.P.1    Rerko, R.M.2    Hata, M.3    Locksley, R.M.4
  • 115
    • 0033830087 scopus 로고    scopus 로고
    • In experimental leishmaniasis deficiency of CD18 results in parasite dissemination associated with altered macrophage functions and incomplete Th1 cell response
    • Schonlau, F., Scarffetter-Kocanek, K. Grabbe, S., Pietz, B., Sorg, C. and Sunderkotter, C. 2000. In experimental leishmaniasis deficiency of CD18 results in parasite dissemination associated with altered macrophage functions and incomplete Th1 cell response. Eur. J. Immunol 30:2729.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 2729
    • Schonlau, F.1    Scarffetter-Kocanek, K.2    Grabbe, S.3    Pietz, B.4    Sorg, C.5    Sunderkotter, C.6
  • 116
    • 0025819340 scopus 로고
    • Induction of interferon gamma production by natural killer cell stimulatory factor: Characterization of the responder cells and synergy with other inducers
    • Chan, S. H., Perussia, B., Gupta, J. W., Kobayashi, M., Pospisil, M., Young, H. A, Wolf, S. F., Young, D., Clark, S. C., Trinchieri, G. 1991. Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers. J. Exp. Med. 173:869.
    • (1991) J. Exp. Med. , vol.173 , pp. 869
    • Chan, S.H.1    Perussia, B.2    Gupta, J.W.3    Kobayashi, M.4    Pospisil, M.5    Young, H.A.6    Wolf, S.F.7    Young, D.8    Clark, S.C.9    Trinchieri, G.10
  • 117
    • 7144259082 scopus 로고    scopus 로고
    • Regulatory CD4 T cells: Expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency
    • Papiernik, M., de Moraes, M. L., Pantoux, C., Vasseur, F., Penit, C. 1998. Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency. Int. Immunol. 10:371.
    • (1998) Int. Immunol. , vol.10 , pp. 371
    • Papiernik, M.1    De Moraes, M.L.2    Pantoux, C.3    Vasseur, F.4    Penit, C.5
  • 118
    • 0025352196 scopus 로고
    • IL-2 a cofactor for induction of activated macrophage resistance to infection
    • Belosevic, M., Finbloom, D. S., Meltzer, M. S., Nacy, C. A. 1990. IL-2 a cofactor for induction of activated macrophage resistance to infection. J. Immunol. 145:831.
    • (1990) J. Immunol. , vol.145 , pp. 831
    • Belosevic, M.1    Finbloom, D.S.2    Meltzer, M.S.3    Nacy, C.A.4
  • 119
    • 0027955893 scopus 로고
    • Interleukin-2 suppresses activated macrophage intracellular killing activity by inducing macrophages to secrete TGF-beta
    • Nelson, B. J., Danielpour, D., Rossio, J. L., Turpin, J., Nacy C. A. 1994. Interleukin-2 suppresses activated macrophage intracellular killing activity by inducing macrophages to secrete TGF-beta. J. Leukoc. Biol. 55:81.
    • (1994) J. Leukoc. Biol. , vol.55 , pp. 81
    • Nelson, B.J.1    Danielpour, D.2    Rossio, J.L.3    Turpin, J.4    Nacy, C.A.5
  • 121
    • 0026570426 scopus 로고
    • Cytokine control of Leishmania infection in the BALB/c mouse: Enhancement and inhibition of parasite growth by local administration of IL-2 or IL-4 is species and time dependent
    • Lezama-Davila, C. M., Williams, D. M., Gallagher, G. and Alexander, J. 1992. Cytokine control of Leishmania infection in the BALB/c mouse: enhancement and inhibition of parasite growth by local administration of IL-2 or IL-4 is species and time dependent. Parasite. Immunol. 14:37.
    • (1992) Parasite. Immunol. , vol.14 , pp. 37
    • Lezama-Davila, C.M.1    Williams, D.M.2    Gallagher, G.3    Alexander, J.4
  • 123
    • 0033555789 scopus 로고
    • Anti-TGF-β treatment promotes rapid healing of Leishmania major infection in mice by enhancing in vivo nitric oxide production
    • Li, J., Hunter, Ch. A. and Farrell, J. P. 1992. Anti-TGF-β treatment promotes rapid healing of Leishmania major infection in mice by enhancing in vivo nitric oxide production. J. Immunol. 162:974.
    • (1992) J. Immunol. , vol.162 , pp. 974
    • Li, J.1    Hunter, Ch.A.2    Farrell, J.P.3
  • 124
    • 0030051658 scopus 로고    scopus 로고
    • Regulation of murine macrophage IL-12 production: Activation of macrophages in vivo restimulation in vitro and modulation by other cytokines
    • Skeen, M. J., Miller, M. A., Shinnick, T. M. and Ziegler, H. K. 1996. Regulation of murine macrophage IL-12 production: activation of macrophages in vivo restimulation in vitro and modulation by other cytokines. J. Immunol. 156:1196.
    • (1996) J. Immunol. , vol.156 , pp. 1196
    • Skeen, M.J.1    Miller, M.A.2    Shinnick, T.M.3    Ziegler, H.K.4
  • 125
    • 0032519412 scopus 로고    scopus 로고
    • TGF-β promotes immune deviation by altering accessory signals of antigen-presenting cells
    • Takeuchi, M., Alard, P. and Streilen, J. W. 1998. TGF-β promotes immune deviation by altering accessory signals of antigen-presenting cells. J. Immunol. 160:1589-1597.
    • (1998) J. Immunol. , vol.160 , pp. 1589-1597
    • Takeuchi, M.1    Alard, P.2    Streilen, J.W.3
  • 126
    • 0026457998 scopus 로고
    • Contrasting mechanisms for suppression of macrophage cytokine release by Transforming growth factor-β and IL-10
    • Bogdan, C., Paik, J., Vodovotz, Y. and Nathan, C. 1992. Contrasting mechanisms for suppression of macrophage cytokine release by Transforming growth factor-β and IL-10. J. Biol. Chem. 267:23301.
    • (1992) J. Biol. Chem. , vol.267 , pp. 23301
    • Bogdan, C.1    Paik, J.2    Vodovotz, Y.3    Nathan, C.4
  • 127
    • 0027203305 scopus 로고
    • Mechanism of suppression of macrophage nitric oxide released by TGF-β
    • Vodovotz, Y., Bogdan, C., Paik, J., Xie, Q. W. and Nathan, C. 1993. Mechanism of suppression of macrophage nitric oxide released by TGF-β. J. Exp. Med. 178:605.
    • (1993) J. Exp. Med. , vol.178 , pp. 605
    • Vodovotz, Y.1    Bogdan, C.2    Paik, J.3    Xie, Q.W.4    Nathan, C.5
  • 128
    • 0025768733 scopus 로고
    • Production of interferon-γ, interleukin 2, interleukin 4, interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leishmaniasis
    • Heinzel, F. P., Sadick, M.D., Mutha, S. S. and Locksley, R. M. 1991. Production of interferon-γ, interleukin 2, interleukin 4, interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leishmaniasis. Proc. Natl. Acad. Sci. USA. 88:7011.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7011
    • Heinzel, F.P.1    Sadick, M.D.2    Mutha, S.S.3    Locksley, R.M.4
  • 129
    • 0013480140 scopus 로고
    • IL-10 inhibits antimicrobial activity against Leishmania major in murine macrophages
    • Vieth, M., Will, A., Schropprl, K., Rollinghoff, M. and Gessner, A. 1994. IL-10 inhibits antimicrobial activity against Leishmania major in murine macrophages. Scand. J. Immunol. 156:644.
    • (1994) Scand. J. Immunol. , vol.156 , pp. 644
    • Vieth, M.1    Will, A.2    Schropprl, K.3    Rollinghoff, M.4    Gessner, A.5
  • 130
    • 0027199519 scopus 로고
    • IL-4 and IL-10 sinergize to inhibit cell-mediated Immunity in vivo
    • Powrie, F., Menon, S. and Coffman, R. L. 1993. IL-4 and IL-10 sinergize to inhibit cell-mediated Immunity in vivo. Eur. J. Immunol. 23:2223.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2223
    • Powrie, F.1    Menon, S.2    Coffman, R.L.3
  • 131
    • 0032898950 scopus 로고    scopus 로고
    • Experimental Leishmania major infection in mice: Role of IL-10
    • Chatelain, R., Mauze, S. and Coffman, R. 1999. Experimental Leishmania major infection in mice: role of IL-10. Parasite. Immunol. 21:211.
    • (1999) Parasite. Immunol. , vol.21 , pp. 211
    • Chatelain, R.1    Mauze, S.2    Coffman, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.