Susceptibility to infectious diseases: Leishmania as a paradigm

Journal of Infectious Diseases

Volumn 179, Issue SUPPL. 2, 1999, Pages

  Locksley, Richard M ^a   Pingel, Sabine ^a   Lacy, Dee ^a   Wakil, Adil E ^a   Bix, Mark ^a   Fowell, Deborah J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4;

ANIMAL CELL; CONFERENCE PAPER; CYTOKINE PRODUCTION; HELPER CELL; HOST RESISTANCE; IMMUNE RESPONSE; INFECTION SENSITIVITY; LEISHMANIA; LYMPHOCYTE DIFFERENTIATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 0033371560     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/513843     Document Type: Conference Paper

References (19)

1. 1. Reiner SL, Locksley RM. The regulation of immunity to Leishmania major. Annu Rev Immunol 1995; 13:151-77.
2. 2. Beebe AM, Mauze S, Schork NJ, Coffman RL. Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice. Immunity 1997; 6:551-7.
3. 2 populations of mice. Eur J Immunogenet 1993; 20:335-48.
4. 4. Roberts M, Mock BA, Blackwell JM. Mapping of genes controlling Leishmania major infection in CXS recombinant mice. Eur J Immunogenet 1993; 20:349-62.
5. 5. Roberts LJ, Baldwin TM, Curtis JM, Handman E, Foote SJ. Resistance to Leishmania major is linked to the H-2 region on chromosome 17 and to chromosome 9. J Exp Med 1997; 185:1705-10.
6. 6. Guler ML, Gorham JD, Hsieh CS, et al. Genetic susceptibility to Leishmania: IL-12 responsiveness in Th1 cell development. Science 1996; 271:984-7.
7. 7. Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996; 383:787-93.
8. + effector cells default to the Th2 pathway in TFN-γ-deficient mice infected with Leishmania major. J Exp Med 1994; 179:1367-72.
9. 9. Mattner F, Magram J, Ferrante J, et al. Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur J Immunol 1996; 26:I553-9.
10. 10. Kopf M, Brombacher F, Kohler G, et al. IL-4-deficient BALB/c mice resist infection with Leishmania major. J Exp Med 1996; 184:1127-36.
11. + T cells instructs Th2 development and susceptibility to Leishmania major in BALB/c mice. Immunity 1997; 6:541-9.
12. 12. Reiner SL, Wang ZE, Hatam F, Scott P, Locksley RM. Th1 and Th2 cell antigen receptors in experimental leishmaniasis. Science 1993; 259: 1457-60.
13. 13. Mougneau E, Altare F, Wakil AE, et al. Expression cloning of a protective Leishmania antigen. Science 1995; 268:563-6.
14. 14. Julia V, Rassoulzadegan M, Glaichenhaus N. Resistance to Leishmania major induced by tolerance to a single antigen. Science 1996; 274: 421-3.
15. 15. Reiner SL, Fowell DJ, Moskowitz NH, et al. Control of Leishmania major by a monoclonal antibody T cell repertoire. J Immunol 1998; 160: 884-9.
16. 16. Hsieh CS, Macatonia SE, O'Garra A, Murphy KM. T cell genetic background determines default T helper phenotype development in vitro. J Exp Med 1995; 181:713-21.
17. 17. Gieni RS, Fang Y, Trinchieri G, Umetsu D, DeKruyff RH. Differential production of IL-12 in BALB/c and DBA/2 mice controls IL-4 versus IFN-gamma synthesis in primed CD4 lymphocytes. Int Immunol 1996; 8:1511-20.
18. 18. Gorham JD, Guler ML, Steen RG, et al. Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses. Proc Natl Acad Sci USA 1996; 93:12467-72.
19. 19. Guery JC, Galbiati F, Smiroldo S, Adorini L. Non-MHC-linked Th2 cell development induced by soluble protein administration predicts susceptibility to Leishmania major infection. J Immunol 1997; 159: 2147-53.