The peripheral benzodiazepine receptor: A promising therapeutic drug target

Current Medicinal Chemistry

Volumn 10, Issue 16, 2003, Pages 1563-1572

  Galiegue, Sylvaine ^a   Tinel, Norbert ^a   Casellas, Pierre ^a  

^a SANOFI   (France)

Author keywords

Arthritis; Benzodiazepine; Cancer; Infection; Inflammation; Neurodegenerative disorders; PBR; SSR180575

Indexed keywords

2 [4 (7 CHLORO 2 QUINOXALINYLOXY)PHENOXY]PROPIONIC ACID; 4' CHLORODIAZEPAM; ACETAMIDE DERIVATIVE; ADENINE NUCLEOTIDE TRANSLOCASE; AMIDE; ANION CHANNEL; ANTIINFLAMMATORY AGENT; ANTIMALARIAL AGENT; ANTINEOPLASTIC AGENT; BENZODIAZEPINE RECEPTOR; BENZODIAZEPINE RECEPTOR AFFECTING AGENT; CARRAGEENAN; DAUNORUBICIN; FGIN 1 27; FLURAZEPAM; GEMCITABINE; GINKGO BILOBA EXTRACT; GINKGOLIDE B; HEME; IFOSFAMIDE; INDOLE DERIVATIVE; INTERLEUKIN 1; LIGAND; MELPHALAN; MEMBRANE PROTEIN; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; PORPHYRIN; SSR 180575; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; VOLTAGE GATED CHANNEL FORMING PROTEIN; XK 469;

ANION TRANSPORT; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; AUTOIMMUNE DISEASE; BODY DISTRIBUTION; CANCER; CELL PROLIFERATION; CLINICAL TRIAL; DEGENERATIVE DISEASE; DRUG MECHANISM; DRUG TARGETING; HEME SYNTHESIS; HUMAN; INFECTION; MEDICAL LITERATURE; MITOCHONDRIAL MEMBRANE; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; REVIEW; STEROIDOGENESIS; STRUCTURE ACTIVITY RELATION; TREATMENT INDICATION;

EID: 0041809082     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867033457223     Document Type: Review

References (104)

1. Braestrup, C., Squires R.F. Proc. Natl. Acad. Sci. USA, 1977, 74, 3805.
2. Anholt, R.R, De Souza, E.B, Oster-Granite, M.L, Snyder, S.H. J. Pharmacol. Exp. Ther., 1985, 233 (2), 517.
3. Guidotti, A., Forchetti, C.M., Corda, M.G., Kennel, D., Bennett, C.D., Costa, E. Proc. Natl. Acad. Sci. USA, 1983, 80, 3531.
4. Costa, E., Guidotti, A. Life Sci., 1991, 49 (5), 325.
5. Verma, A., Nye, J.S., Snyder, S.H. Proc. Natl. Acad. Sci., 1987, 84, 2256.
6. Li, H., Papadopoulos V. Endocrinology, 1998, 139, 4991.
7. Farges, R., Joseph-Liauzun, E., Shire, D., Caput, D., Le Fur, G., Ferrara, P. Mol. Pharmacol., 1994, 46, 1160.
8. Le Fur, G., Perrier, M.L., Vaucher, N., Imbault, F., Flamier, A., Benavides, J., Uzan, A., Renault, C., Dubroeucq, M.C., Gueremy, C. Life Sci., 1983, 32, 1839.
9. Le Fur, G., Vaucher, N., Perrier M.L., Flamier, A., Benavides, J., Renault, C., Dubroeucq, M.C., Gueremy, C., Uzan, A. Life Sci., 1983, 33, 449.
10. Romeo, F., Auta J., Kozikowski, A.P., Ma, D., Papadopoulos, V., Puia, G., Costa, E., Guidotti, A. J. Pharmacol. Exp. Ther., 1992, 262 (3), 971.
11. Ferzaz, B., Brault, E., Bourliaud, G., Robert, J.P., Poughon, G., Claustre, Y., Marguet, F., Liere, Ph., Shumacher, M., Nowicki, J.P., Fournier, J., Marabout, B., Sevrin, M., Pascal, G., Soubrie, Ph., Benavides, J., Scatton, B. J. Pharmacol. Exp. Ther., 2002, 301 (3), 1067.
12. Bribes, E, Bourrie, B, Esclangon, M, Galiegue, S, Vidal, H, Casellas, P. Eur. J. Pharmacol., 2002, 452 (1), 111.
13. Olson, J.M., Ciliax, B.J., Mancini, W.R., Young, A.B. Eur. J. Pharmacol., 1988, 152, 47.
14. O'Beirne, G.B., Woods, M.J., Williams, D.C. Eur. J. Biochem., 1990, 188, 131.
15. Hardwick, M., Fertikh, D., Culty, M., Li, Hua, Vidic, B., Papadopoulos, V. Cancer Research, 1999, 59, 831.
16. Anholt, R.R.H., Pedersen, P.L., De Souza, E.B., Snyder, S.H. J. Biol. Chem., 1986, 261, 576.
17. Bernassau, J.M., Reversat, J.L., Ferrara, P., Caput, D., LeFur, G. J. Mol. Graphics, 1993, 11, 236.
18. Me Enery, M.W., Snowman, A.M., Trifiletti, R.R., Snyder, S.H. Proc. Natl. Acad. Sci. USA, 1992, 89, 3170.
19. Galiegue, S., Jbilo, O., Combes, T., Bribes, E., Carayon, P., Le Fur, G., Casellas, P. J. Biol. Chem., 1999, 270, 2938.
20. Blahos, J., Whalin, M.F., Krueger, K.F. J. Biol. Chem., 1995, 270, 20285.
21. Li, H., Degenhardt, B., Teper, G., Papadopoulos, V. Proc Natl. Acad. Sci. USA, 2001, 98, 1267.
22. West, L.A., Horvat, R.D., Roess, D.A., Barisas, B.G., Juengel, J.L., Niswender, G.D. Endocrinology, 2001, 142, 502.
23. Li, H., Degenhardt, B., Todin, D., Yao, Z.X, Tasken, K., Papadopoulos, V. Mol. Endocrinol., 2001, 15 (12), 2211.
24. Papadopoulos, V., Amri, H., Boujrad, N., Cascio, C., Culty, M., Garnier, M., Hardwick, M., Li, H., Vidic, B., Brown, A.S., Reversa, J.L., Bernassau, J.M., Drieu, K. Steroids, 1997, 62, 21.
25. Beurdeley-Thomas, A., Miccoli, L., Oudard, S., Dutrillaux, B., Poupon, M.F. J. Neurooncol., 2000, 46 (1), 45.
26. Casellas, P., Galiegue, S., Basile, A.S. Neurochem. Int., 2002, 40(6), 475.
27. Besman, M.J., Yanagibashi, K., Lee, T.D., Kawamura, M., Hall, P.F., Shively, J.E. Proc. Natl. Acad, Sci. USA, 1989, 86, 4897.
28. Papadopoulos, V., Amri, H., Li, H., Boujrad, N., Vidic, B., Garnier, M. J. Biol. Chem., 1997, 272, 32129.
29. Li H., Papadopoulos, V. Endocrinology, 1998; 139(12):4991.
30. Carayon, P., Portier, M., Dussossoy, D., Bord, A., Petitpretre, G., Canat, X., Le Fur, G., Casellas, P. Blood, 1996, 87(8), 3170.
31. Hirsch, T., Decaudin, D., Susin, S.A., Marchetti, P., Larochette, N., Resche-Rigon, M., Kroemer, G. Experimental Cellular Research, 1998, 241, 426.
32. Bono, F., Lamarche, I., Prabonnaud, V., Le Fur, G., Herbert, J.M. Biochem. Biophys. Res. Comm., 1999, 265, 457.
33. Gavish, M.J. Steroid. Biochem. Mol. Biol., 1995, 53, 57.
34. Golani, I., Weizman, A., Leschiner, S., Spanier, I., Eckstein, N., Limor, R., Yanai, J., Maaser, K., Scherubl, H., Weisinger, G., Gavish M. Biochemistry, 2001, 40, 10213.
35. Moynagh, P.N., O'Neill, L.A.J., Williams, D.C. Biochem. Pharmacol., 1993, 46, 821.
36. Rey, C., Mauduit, C., Naureils, O., Benahmed, M., Louisot, P., Gasnier, F. Biochem. Pharmacol., 2000, 60, 1639.
37. Trincavelli, M.L., Marselli, L., Falleni, A., Gremigni, V., Ragge, E., Dotta, F., Santangelo, C., Marchetti, P., Lucacchini, A., Martini, C. J. Cell Biochem., 2002, 84, 636.
38. Itzhak, Y., Norenberg, M.D. Brain Res., 1994, 660 (2), 346.
39. Owen, F., Poulter, M., Waddigton, J.L., Mashal, R.D., Crow, T.J. Br. Res., 1983, 273, 373.
40. Holmes, P.V., Drugan, R.C. Psychoneuroendocrynology, 1994, 19, 43.
41. Miettinen, H., Kononen, J., Haapasalo, H., Helen, P., Sallinen, P., Harjuntausta, T., Helin, H., Alho, H. Cancer Res., 1995, 55, 2691.
42. Katz, Y., Ben-baruch, G., Kloog, Y., Menczer, J., Gavish, M. Clin. Sci., 1990, 78, 155.
43. Katz, Y., Eitan, A., Gavish, M. Oncology, 1990, 47, 139.
44. Venturini., Alho, H., Podkletnova, I., Corsi, L., Rybnikova, E., Pellicci, R., Baraldi, M., Pelto-Huikko, M., Helen, P., Zenoroli, M.L. Life Sci., 1999, 65, 2223.
45. Miyazawa, N., Hamel, E., Diksic, M. J. Neurooncol., 1998, 38(1), 19.
46. Beinlich, A., Strohmeier, R., Kaufmann, M., Kuhl, H. Biochem. Pharmacol., 2000, 60(3), 397.
47. Hardwick, M., Rone, J., Han, Z., Haddad, B., Papadopoulos, V. Int. J. Cancer, 2001, 94(3), 322.
48. Brown, R.C., Degenhardt, B., Kotoula, M., Papdopoulos, V. Cancer Lett., 2000, 156, 125.
49. Starosta-Rubinstein, S., Ciliax, B.J., Penney, J.B., McKeever, P., Young, A.B. Proc. Natl. Acad. Sci. USA, 1987, 84(3), 891.
50. Junck, L., Olson, J.M., Ciliax, B.J. Ann. Neurol., 1989, 26, 752.
51. Maaser, K., Grabowski, P., Sutter, A., Höpfner, M., Foss, H.D., Stein, H., Berger, G., Gavish, M., Zeitz, M., Scherubl, H. Clin. Cancer Res., 2002, 8, 3205.
52. Papadopoulos, V., Kapsis, A., Li, H., Amri, H., Hardwick, M., Culty, M., Kasprzyk, P.G., Carlson, M., Moreau, J.P., Drieu, K. Anticancer Res., 2000, 20 (5A), 2835.
53. Amri, H., Ogwuebu, S.O., Boujrad, N., Drieu, K., Papadopoulos, V. Endocrinology, 1996, 137, 5707.
54. Amri, H., Drieu, K., Papadopoulos, V. Cell Mol. Biol, 2002, 48 (6), 633.
55. Verma, A., Facchina, S.L., Hirsch, D.J., Song, S.Y., Dillahey, L.F., Williams, J.R., Snyder, S.H. Mol. Med., 1998, 4(1), 40.
56. Kupczyk-Subotkowska, L., Siahaan, T.J., Basile, A.S., Friedman, H.S., Higgins, P.E., Song, D., Gallo, J.M. J. Med. Chem., 1997, 40(11):1726.
57. Guo, P., Ma, J., Li, S., Guo, Z., Adams, A.L., Gallo, J.M. Cancer Chemother. Pharmacol., 2001, 48(2), 169.
58. Wang, J.K.T., Morgan, J.I., Spector, S. Proc. Natl. Acad. Sci. USA, 1984, 81, 753.
59. Landau, M., Weizman, A., Zoref-Shani, E., Beer, E., Wasseman, L., Landau, O., Gavish, M., Brenner, S., Nordenberg, J. Biochem. Pharmacol., 1998, 56, 1029.
60. Stoebner, P.E., Carayon, P., Casellas, P., Portier, M., Lavabre-Bertrand, T., Cuq, P., Cano, J.P., Meynadier, J., Meunier, L. Cell Death Differ., 2001, 8 (7), 747.
61. Maaser, K., Hopfner, M., Jansen, A., Weisinger, G., Gavish, M., Kozikowski, A.P., Weizman, A., Carayon, P., Riecken, E.O., Zeitz, M., Scherubl, H. Br. J. Cancer, 2001, 85(11), 1771.
62. Sutter, A.P., Maaser, K., Hopfner, M., Barthel, B., Grabowski, P., Faiss, S., Carayon, P., Zeitz, M., Scherubl H. Int. J. Cancer, 2002, 102(4), 318.
63. Kessel, D., Horwitz, J.P. Cancer Lett., 2001, 168(2):141.
64. Jakubikova, J., Duraj, J., Hanukova, L., Chorvath, B., Sedlak, ?. J. Neoplasma, 2002, 49 (4), 231.
65. Decaudin, D., Castedo, M., Nemati, F., Beurdeley-Thomas, A., De Pinieux, G., Caron, A., Pouillart, P., Wijdenes, J., Rouillard, D., Kroemer, G., Poupon, M.F. Cancer Res., 2002, 62(5), 1388.
66. Banker, D.E., Cooper, J.J., Fennell, D.A., Willman, C.L., Appelbaum, F.R., Cotter, F.E. Leuk. Res., 2002, 26(1), 91.
67. Benavides, J., Dubois, A., Dennis, T., Hamel, E., Scatton, B. J. Pharmacol. Exp. Ther., 1989, 249, 333.
68. Canat, X., Carayon, P., Bouaboula, M., Cahard, D., Shire, D., Roque, C., Le Fur, G., Casellas, P. Life Sci., 1992, 52, 107.
69. Vowinckel, E., Reutens, D., Becher, B., Verge, G., Evans, A., Owens, T, Antel, J.P. J. Neurosci. Res., 1997, 50, 345.
70. Gehlert, D.R., Stephenson, D.T., Schober, D.A., Rash, K., Clemens, J.A. Neurochem. Int., 1997, 31, 705.
71. Lacor, P., Gandolfo, P., Tonon, M.C., Brault, E., Dalibert, I., Schumacher, M., Benavides, J., Ferzaz, B. Brain Res., 1999, 815, 70.
72. Scatton, B., Benavides, J., Dubois, A., Bourdiol, F. Int. J. Tiss. Reac., 1990, 12, 15.
73. Ruff, M.R., Pert, C.B., Weber, R.J., Wahl, L.M., Wahl, S.M., Paul, S.M. Science, 1985, 229:1281.
74. Zavala, F., Taupin, V., Descamps-Latscha, B. J. Pharmacol. Exp. Ther., 1990, 225, 442.
75. Schreiber, A.A., Frei, K., Lichtensteiger, W., Schlumpf, M. Agent Actions, 1993, 38, 265.
76. Torres, S.R., Fröde, T.S., Nardi, G.M., Vita, N., Reeb, R., Ferrara, P., Ribeiro-do-Valle, R.M., Farges, R.C. Eur. J. Pharmacol., 2000, 408:199.
77. Waterfield, J.D., Me Geer, E.G., Mc Geer, P.L. Rheumatology, 1999, 38:1068.
78. Bribes, E., Galiegue, S., Bourrie, B., Casellas, P. Immunol. Lett., 2003, 2; 85 (1),13.
79. Torres, S.R., Nardi, G.M., Ferrara, P., Ribeiro-do-Valle, R.M., Farges, R.C. Eur. J. Pharmacol., 1999, 385 (2-3), R1.
80. Johnston, C., Jiang, W., Chu, T., Levine, B. J. Virol., 2001, 75 (21), 10431.
81. Dzierszinski, F., Coppin, A., Mortuaire, M., Dewailly, E., Slomianny, C., Ameisen, J.C., Debels, F., Tomavo, S. Antimicrob. Agents and Chemother., 2002, 46 (10), 3197.
82. Everett, H., Barry, M., Sun., X., Lee, S.F., Frantz, C., Berthiaume, L.G., McFadden, G., Bleackly, R.C. J. Exp. Med., 2002, 196, 1127.
83. Anholt, R.R., Murphy, K.M., Mack, G.E., Snyder, S.H. J. Neurosc., 1984, 4, 593.
84. Banati, R.B., Myers, R., Kreutzberg, G.W. Journal of Neurocytology, 1997, 26, 77.
85. Desjardins, P., Butterworth, R.F. Neurochem. Int., 2002, 41 (2-3), 109.
86. Raghavendra, R.V.L., Dogan, A., Bowen, K.K., Dempsey, R.J. Exp. Neurol., 2000, 161, 102.
87. Stevenson, D.T., Schober, D.A., Smalstig, E.B., Mincy, R.E., Gehlert, D.R., Clemens, J.A. J. Neurosci., 1995, 15, 5263.
88. Kuhlmann, A.C., Guilarte, T.R. Brain Res., 1997, 751, 281.
89. Kuhlmann, A.C., Guilarte, T.R. J. Neurochem., 2000, 74, 1694.
90. Diorio, D., Welner, S.A., Butterworth, R.F., Meaney, M.J., Suranyi-Cadotte, B.E. Neurobiology of Aging, 1991, 12, 255.
91. Messmer, K., Reynolds, G.P. Neuroscience Letters, 1998, 241, 53.
92. Johnson, E.W., de Lanerolle, N.C., Kim, J.M., Sundaresan, S., Spencer, D.D., Mattson, R.H., Zoghbi, S.S., Baldwin, R.M., Hoffer, P.B., Seibyl, J.P. Neurology, 1992, 42, 811.
93. Sauvageau, A., Desjardins, P., Lozeva, V., Rose, C., Hazell, A.S., Bouthillier, A., Butterwort, R.F. Metab. Brain Dis., 2002, 17(1), 3.
94. Cagnin, A., Brooks, D.J., Kennedy, A.M., Gunn, R.N., Myers, R., Turkheimer, F.E., Jones, T., Banati, R.B. Lancet, 2001, 358(9280), 461.
95. Cagnin, A., Myers, R., Gunn, R.N., Lawrence, A.D., Stevens, T., Kreutzberg, G.W., Jones, T., Banati, R.B. Brain, 2001, 124(Pt 10), 2014.
96. Debruyne, J.C., Van Laere, K.J., Versijpt, J., De Vos, F., Eng, J.K., Strijckmans, K., Santens, P., Achten, E., Slegers, G., Korf, J., Dierckx, R.A., De Reuck, J.L. Acta Neurol. Belg., 2002, 102(3), 127.
97. Lacor, P., Benavides, J., Ferzaz, B. Neurosci. Lett., 1996, 220(1), 61.
98. Holmes, P.V., Drugan, R.C. Psychoneuroendocrynology, 1994, 19, 43.
99. Drugan, R.C. Clin. Neuropharmacol., 1996, 19, 475.
100. Ferrarese, C., Mennini, T., Pecora, N., Pierpaoli, C., Frigo, M., Marzorati, C., Gobbi, M., Bizzi, A., Coregoni, A., Garattini, S. Neuropharmacol., 1991, 30, 1445.
101. Burgin, R., Weizman, R., Gavish, M. Neuropsychobiology, 1996, 33, 28.
102. Kroemer, G., Reed, J.C. Nature Medicine, 2000, 6, 513.
103. Fennell, D.A., Corbo, M., Pallaska, A., Cotter, F.E. Br. J. Cancer, 2001, 84 (10),1397.
104. Castedo, M., Perfettini, J.L., Kroemer, G. J. Exp. Med., 2002, 196 (9),1121.