Transient protection by peripheral benzodiazepine receptors during the early events of ultraviolet light-induced apoptosis

Cell Death and Differentiation

Volumn 8, Issue 7, 2001, Pages 747-753

  Stoebner, P E ^a   Carayon, P ^b   Casellas, P ^b   Portier, M ^b   Lavabre Bertrand, T ^c   Cuq, P ^d   Cano, J P ^d   Meynadier, J ^a   Meunier, L ^a  

^a MONTPELLIER UNIVERSITY HOSPITAL   (France)

^b SANOFI   (France)

^c NÎMES UNIVERSITY HOSPITAL   (France)

^d Laboratory of Drug Toxicology   (France)

Author keywords

Apoptosis; Mitochondria; Peripheral benzodiazepine receptor; Ultraviolet

Indexed keywords

BENZODIAZEPINE RECEPTOR; CASPASE 3; SUPEROXIDE;

APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; GENE FUNCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LIGHT EXPOSURE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ULTRAVIOLET B RADIATION;

APOPTOSIS; CASPASE 3; CASPASES; ENZYME ACTIVATION; HUMANS; INTRACELLULAR MEMBRANES; JURKAT CELLS; MEMBRANE POTENTIALS; MITOCHONDRIA; PERMEABILITY; RECEPTORS, GABA-A; SUPEROXIDES; TRANSFECTION; ULTRAVIOLET RAYS;

EID: 0034921466     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400861     Document Type: Article

References (41)

1. Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding
2. The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane
3. Porphyrins are endogenous ligands for the mitochondrial (peripheral-type) benzodiazepine receptor
4. Cloning and characterization of PRAX-1. A new protein that specifically interacts with the peripheral benzodiazepine receptor
5. Molecular and functional properties of mitochondrial benzodiazepine receptors
6. A mammalian mitochondrial drug receptor functions as a bacterial 'oxygen' sensor
7. TspO of rhodobacter sphaeroides. A structural and functional model for the mammalian peripheral benzodiazepine receptor
8. Isolation of the mitochondrial benzodiazepine receptor: Association with voltage-dependent anion channel and the adenine nucleotide carrier
9. Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
10. The proto-oncogene Bcl-2 and its role in regulating apoptosis
11. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
12. Mitochondrial control of apoptosis
13. Adenine nucleotide translocase-1, a component of the permeability transition pore, can dominantly induce apoptosis
14. Involvement of peripheral bnezodiazepine receptors in the protection of hematopoietic cells against oxygen radical damage
15. PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection
16. Peripheral benzodiazepine receptor agonists exhibit potent antiapoptotic activities
17. The expression of peripheral benzodiazepine receptors in human skin: The relationship with epidermal cell differentiation
18. Development of a monoclonal antibody to immunocytochemical analysis of the cellular localization of the peripheral benzodiazepine receptor
19. Mitochondrial permeability transition is a central coordinating event of apoptosis
20. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
21. Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2′,7′-dichlorofluorescin
22. Activation of p38 mitogen-activated protein kinase and caspases in UVB-induced apoptosis of human keratinocyte HaCat cells
23. Suicidal tendencies: Apoptotic cell death by caspase family proteinases
24. Light and death: Photons and apoptosis
25. Mitochondrial control of nuclear apoptosis
26. Mitochondria and apoptosis
27. The permeability transition pore complex: A target for apoptosis regulation by caspases and bcl-2-related proteins
28. Benzodiazepine receptor agonists modulate thymocyte apoptosis through reduction of the mitochondrial transmembrane potential
29. Mitochondrial permeability transition triggers lymphocyte apoptosis
30. The regulation of reactive oxygen species production during programmed cell death
31. Role of ultraviolet A-induced oxidative DNA damage in apoptosis via loss of mitochondrial membrane potential and caspase-3 activation
32. The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant
33. Distinct stages of cytochrome c release from mitochondria: Evidence for a feedback amplification loop linking caspase activation to mitochondrial dysfunction in genotoxic stress induced apoptosis
34. Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis
35. Caspases induce cytochrome c release from mitochondria by activating cytosolic factors
36. Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c
37. Emerging roles of caspase-3 in apoptosis
38. Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation
39. Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L
40. Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: A potential feedback loop for amplification of cytochrome c release
41. Tumor selective G2/M cell cycle arrest and apoptosis of epithelial and hematological malignancies by BBL22, a benzazepine