Enhanced expression of the peripheral benzodiazepine receptor (PBR) and its endogenous ligand octadecaneuropeptide (ODN) in the regenerating adult rat sciatic nerve

Neuroscience Letters

Volumn 220, Issue 1, 1996, Pages 61-65

  Lacor, Pascale ^a   Benavides, Jesús ^a   Ferzaz, Badia ^a  

^a SANOFI   (France)

Author keywords

chronic denervation; octadecaneuropeptide; peripheral benzodiazepine receptor; peripheral nerve regeneration; Schwann cells

Indexed keywords

BENZODIAZEPINE RECEPTOR; NEUROPEPTIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; NERVE INJURY; NERVE REGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; SCHWANN CELL; SCIATIC NERVE;

ANIMALS; DENERVATION; DIAZEPAM BINDING INHIBITOR; MACROPHAGES; MALE; NERVE REGENERATION; NEUROPEPTIDES; PEPTIDE FRAGMENTS; RATS; RECEPTORS, GABA-A; SCHWANN CELLS; SCIATIC NERVE;

EID: 0030572997     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(96)13187-6     Document Type: Article

References (33)

1. 3H]diazepam binding, Proc. Natl. Acad. Sci. USA, 74 (1977) 3805-3809.
2. 3H]Ro5-4864 to benzodiazepine binding sites in rat cerebral cortex, Eur. J. Pharmacol., 71 (1981) 473-475.
3. [3] McEnery, M.W., Snowman, A.M., Trifiletti, R.R. and Snyder, S.H., Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenin nucleotide carrier, Science, 89 (1992) 3170-3174.
4. [4] De Souza, E.B., Anholt, R.R., Murphy, K.M., Snyder, S.H. and Kuhar, M.J., Peripheral-type benzodiazepine receptors in endocrine organs: autoradiographic localization in rat pituitary, adrenal, and testis, Endocrinology, 116 (1985) 567-573.
5. 3H]R05-4864, Eur. J. Pharmacol., 95 (1983) 329-330.
6. 3 binding sites in the immune organs and leg infiltrate of rats with adjuvant induced arthritis, Int. J. Tissue React., 12 (1990) 15-20.
7. 3H]PK 11195 and autoradiographic localization, Arch. Int. Pharmacodyn., 266 (1983) 38-49.
8. [8] Zavala, F., Haumont, J. and Lenfant, M., Interaction of benzodiazepines with mouse macrophages, Eur. J. Pharmacol., 106 (1984) 561-566.
9. 3H]PK 11195, Studies in hypertensive patients, Biochem. Pharmacol., 33 (1984) 2467-2472.
10. 3H]PK 11195, an isoquinoline carboxamide derivative: kinetic studies and autoradiographic localization, J. Neurochem., 41 (1983) 1744-1750.
11. [11] Itzhak, Y., Baker, L. and Norenberg, M., Characterization of the peripheral-type benzodiazepine receptors in cultured astrocytes: evidence for multiplicity, Glia, 9 (1993) 211-218.
12. [12] Stephenson, D.T., Schober, D.A., Smalstig, E.B., Mincy, R.E., Gehlert, D.R. and Clemens, J.A., Peripheral benzodiazepine receptors are colocalized with activated microglia following transient global forebrain ischemia in the rat, J. Neurosci., 15 (1995) 5263-5274.
13. 3H]PK 14105, Neurosci. Lett., 114 (1990) 32-38.
14. [14] Guidotti, A., Ahlo, H., Berkovich, A., Cox, C., Ferrarese, C., Slobodyansky, E., Santi, M.R. and Wambebe, C., DB1 processing: allosteric modulation at different GABA benzodiazepine receptor subtypes. In E. Costa and E. Barnard (Eds.), Allosteric Modulation of Amino Acid Receptors: Therapeutic Implications, Raven Press, New York, 1988, pp. 109-123.
15. [15] Costa, E. and Guidotti, A., Diazepam binding inhibitor (DBI): a peptide with multiple biological actions, Life Sci., 49 (1991) 325-344.
16. [16] Rouet-Smih, F., Tonon, M.C., Pelletier, G. and Vaudry, H., Characterization of endozepine-related peptides in the central nervous system and in peripheral tissues of the rat, Peptides, 13 (1992) 1219-1225.
17. [17] Brown, A.S., Hall, P.F., Shoyab, M. and Papadopoulos, V., Endozepine/diazepam binding inhibitor in adrenocortical and Leydig cell lines: absence of hormonal regulation, Mol. Cell. Endocrinol., 83 (1992) 1-9.
18. [18] Papadopoulos, V., Guarneri, P., Krueger, K.E., Guidotti, A. and Costa, E., Pregenolone biosynthesis in C6 glioma cell mitochondria: regulation by a diazepam binding inhibitor mitochondrial receptor, Proc. Natl. Acad. Sci. USA, 89 (1992) 5113-5117.
19. [19] Alho, H., Bovolin, P. and Slobodyansky, E., Diazepam binding inhibitor (DBI) processing: immunohistochemical studies in the rat brain, Neurochem. Res., 15 (1990) 209-216.
20. [20] Slobodyansky, E., Guidotti, E., Wambebe, C., Berkovich, A. and Costa, E., Isolation and characterization of rat brain triakontatetraneuropeptide (TTN), a posttranslational product of diazepam binding inhibitor (DBI): specific action at the Ro-5-4864 recognition site, J. Neurochem., 53 (1989) 1276-1284.
21. [21] Tonon, M.C., Désy, L., Nicolas, P., Vaudry, H. and Pelletier, G., Immunocytochemical localization of the endogenous benzodiazepine ligand octadecaneuropeptide (ODN) in the rat brain, Neuropeptides, 15 (1990) 17-24.
22. [22] Krueger, K.E., Molecular and functional properties of mitochondrial benzodiazepine receptors, Biochim. Biophys. Acta, 1241 (1995) 453-470.
23. [23] Besman, M.J., Yanagibashi, K., Lee, T.D., Kawamura, M., Hall, P.F. and Shively, J.E., Identification of des-(Gly-Ile)-endozepine as an effector of corticotropin-dependent adrenal steroidogenesis: stimulation of cholesterol delivery is mediated by the peripheral benzodiazepine receptor, Proc. Natl. Acad. Sci. USA, 86 (1989) 4897-4901.
24. [24] Papadopoulos, V., Berkovich, A., Krueger, K.E., Costa, E. and Guidotti, A., Diazepam binding inhibitor (DBI) and its processing products stimulate mitochondrial steroid biosynthesis via an interaction with mitochondrial benzodiazepine receptors, Endocrinology, 129 (1991) 1481-1488.
25. [25] Jones, K.J., Gonadal steroids and neuronal regeneration: a therapeutic role, Adv. Neurol., 59 (1993) 227-240.
26. [26] Koenig, H.L., Schumacher, M., Ferzaz, B., Do Thi, A.N., Ressouches, A., Guennoun, R., Jung-Testas, I., Robel, P., Akwa, Y. and Beaulieu, E.E., Progesterone synthesis and myelin formation by Schwann cells, Science, 268 (1995) 1500-1503.
27. [27] Mira, J.C., Etudes quantitatives sur la régénération des fibres nerveuses myélinisées. III: variations du nombre et du calibre des fibres régénérées après une congélation localisée, Arch. Anat. Micr. Morph. Exp., 66 (1977) 1-16.
28. [28] Riond, J., Mattei, M.G., Kaghad, M., Dumond, X., Guillemot, J.C., Le Fur, G., Caput, D. and Ferrara, P., Molecular cloning and chromosomal localization of a human peripheral type benzodiazepine receptor, Eur. J. Biochem., 195 (1991) 305-311.
29. [29] Stoll, G., Griffin, J.W. and Trapp, B.D., Wallerian degeneration in the peripheral nervous system: participation of both Schwann cells and macrophages in myelin degradation, J. Neurocytol., 18 (1989) 671-683.
30. [30] Röyttä, M. and Salonen, V., Long-term endoneurial changes after nerve transection, Acta Neuropathol. (Berlin), 76 (1988) 35-45.
31. [31] Pellegrino, R.G. and Spencer, P., Schwann cell mitosis in response to regenerating peripheral axons in vivo, Brain Res., 341 (1985) 16-25.
32. [32] Akwa, Y., Schumacher, M., Jung-Testas, I. and Baulieu, E.E., Neurosteroids in rat sciatic nerves and Schwann cells, C.R. Acad. Sci. (III) (Paris), 316 (1993) 410.
33. [33] Taupin, V., Toulmond, S., Serrano, A., Benavides, J. and Flora, S., Increase in IL6, IL1 and TNF levels in rat brain following traumatic lesion. Influence of pre- and post-traumatic treatment with Ro-5 4864, a peripheral type (p site) benzodiazepine ligand, J. Neuroimmunol., 42 (1993) 177.