Inhibition of Fas receptor (CD95)-induced hepatic caspase activation and apoptosis by acetaminophen in mice

Toxicology and Applied Pharmacology

Volumn 156, Issue 3, 1999, Pages 179-186

  Lawson, Judy A ^a   Fisher, Michael A ^a   Simmons, Carol A ^a   Farhood, Anwar ^b   Jaeschke, Hartmut ^a  

^a PFIZER INC   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Acetaminophen hepatotoxicity; Anti Fas antibody Jo 2; Apoptosis; Caspase inhibitor Z VAD; Caspases; CD95; DNA fragmentation; Fas receptor; Liver cell necrosis

Indexed keywords

ALANINE AMINOTRANSFERASE; CASPASE 3; CASPASE INHIBITOR; DNA FRAGMENT; FAS ANTIGEN; PARACETAMOL;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER CELL DAMAGE; MALE; MOUSE; NONHUMAN;

ANIMALIA;

EID: 0033135845     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1999.8635     Document Type: Article

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