Dramatic increase of telomerase activity during dendritic cell differentiation and maturation

Journal of Leukocyte Biology

Volumn 74, Issue 2, 2003, Pages 270-276

  Ping, Lin ^a,b   Asai, Azusa ^a   Okada, Aki ^a   Isobe, Kenichi ^a   Nakajima, Hideo ^a  

^a NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Aging; DC; Telomere

Indexed keywords

CELL MARKER; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; TELOMERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; BONE MARROW CULTURE; CELL ACTIVATION; CELL DIFFERENTIATION; CELL MATURATION; CELL STIMULATION; CELL SURFACE; CONTROLLED STUDY; DENDRITIC CELL; ENZYME ACTIVITY; IN VITRO STUDY; IN VIVO STUDY; INJECTION; MALE; MEASUREMENT; MICROORGANISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; STIMULUS RESPONSE; TELOMERE; ANIMAL; C57BL MOUSE; CYTOLOGY; ENZYMOLOGY; FLOW CYTOMETRY; IMMUNOLOGY; INTRAPERITONEAL DRUG ADMINISTRATION; MACROPHAGE; METABOLISM; PHYSIOLOGY; SPLEEN; UPREGULATION;

ANIMALIA;

ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; DENDRITIC CELLS; FLOW CYTOMETRY; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INJECTIONS, INTRAPERITONEAL; INTERLEUKIN-4; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; SPLEEN; TELOMERASE; UP-REGULATION;

EID: 0041349298     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0103014     Document Type: Article

References (42)

1. Steinman, R. M. (1991) The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 9, 271-296.
2. Banchereau, J., Briere, F., Caux, C., Davoust, J., Lebecque, S., Liu, Y. J., Pulendran, B., Palucka, K. (2000) Immunobiology of dendritic cells. Annu. Rev. Immunol. 18, 767-811.
3. Cella, M., Engering, A., Pinet, V., Pieters, J., Lanzavecchia, A. (1997) Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature 388, 782-787.
4. Pierre, P., Turley, S. J., Gatti, E., Hull, M., Meltzer, J., Mirza, A., Inaba, K., Steinman, R. M., Mellman, I. (1997) Developmental regulation of MHC class II transport in mouse dendritic cells. Nature 388, 787-792.
5. Sallusto, F. (2001) Origin and migratory properties of dendritic cells in the skin. Curr. Opin. Allergy Clin. Immunol. 1, 441-448.
6. Lanzavecchia, A., Sallusto, F. (2001) Regulation of T cell immunity by dendritic cells. Cell 106, 263-266.
7. Rescigno, M., Granucci, F., Citterio, S., Foti, M., Ricciardi-Castagnoli, P. (1999) Coordinated events during bacteria-induced DC maturation. Immunol. Today 20, 200-203.
8. Cella, M., Salio, M., Sakakibara, Y., Langen, H., Julkunen, I., Lanzavecchia, A. (1999) Maturation, activation, and protection of dendritic cells induced by double-stranded RNA. J. Exp. Med. 189, 821-829.
9. Kadowaki, N., Antonenko, S., Liu, Y. J. (2001) Distinct CpG DNA and polyinosinic-polycytidylic acid double-stranded RNA, respectively, stimulate CD11c-type 2 dendritic cell precursors and CD11c+ dendritic cells to produce type I IFN. J. Immunol. 166, 2291-2295.
10. Akira, S., Takeda, K., Kaisho, T. (2001) Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2, 675-680.
11. Greider, C. W. (1996) Telomere length regulation. Annu. Rev. Biochem. 65, 337-365.
12. Blackburn, E. H. (2001) Switching and signaling at the telomere. Cell 106, 661-673.
13. Hastie, N. D., Dempster, M., Dunlop, M. G., Thompson, A. M., Green, D. K., Allshire, R. C. (1990) Telomere reduction in human colorectal carcinoma and with ageing. Nature 346, 866-868.
14. Blackburn, E. H. (2000) Telomere states and cell fates. Nature 408, 53-56.
15. Hackett, J. A., Feldser, D. M., Greider, C. W. (2001) Telomere dysfunction increases mutation rate and genomic instability. Cell 106, 275-286.
16. Bodnar, A. G., Ouellette, M., Frolkis, M., Holt, S. E., Chiu, C. P., Morin, G. B., Harley, C. B., Shay, J. W., Lichtsteiner, S., Wright, W. E. (1998) Extension of life-span by introduction of telomerase into normal human cells. Science 279, 349-352.
17. Vaziri, H., Benchimol, S. (1998) Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span. Curr. Biol. 8, 279-282.
18. Buchkovich, K. J., Greider, C. W. (1996) Telomerase regulation during entry into the cell cycle in normal human T cells. Mol. Biol. Cell 7, 1443-1454.
19. Bodnar, A. G., Kim, N. W., Effros, R. B., Chiu, C. P. (1996) Mechanism of telomerase induction during T cell activation. Exp. Cell Res. 228, 58-64.
20. Ogoshi, M., Takashima, A., Taylor, R. S. (1997) Mechanisms regulating telomerase activity in murine T cells. J. Immunol. 158, 622-628.
21. Hathcock, K. S., Weng, N. P., Merica, R., Jenkins, M. K., Hodes, R. (1998) Cutting edge: antigen-dependent regulation of telomerase activity in murine T cells. J. Immunol. 160, 5702-5706.
22. Herrera, E., Martinez, A. C., Blasco, M. A. (2000) Impaired germinal center reaction in mice with short telomeres. EMBO J. 19, 472-481.
23. Inaba, K., Inaba, M., Romani, N., Aya, H., Deguchi, M., Ikehara, S., Muramatsu, S., Steinman, R. M. (1992) Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176, 1693-1702.
24. Kadowaki, N., Ho, S., Antonenko, S., Malefyt, R. W., Kastelein, R. A., Bazan, F., Liu, Y. J. (2001) Subsets of human dendritic cell precursors express different Toll-like receptors and respond to different microbial antigens. J. Exp. Med. 194, 863-869.
25. De Smedt, T., Pajak, B., Muraille, E., Lespagnard, L., Heinen, E., De Baetselier, P., Urbain, J., Leo, O., Moser, M. (1996) Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo. J. Exp. Med. 184, 1413-1424.
26. Yui, J., Chiu, C. P., Lansdorp, P. M. (1998) Telomerase activity in candidate stem cells from fetal liver and adult bone marrow. Blood 91, 3255-3262.
27. Chaves-Dias, C., Hundley, T. R., Gilfillan, A. M., Kirshenbaum, A. S., Cunha-Melo, J. R., Metcalfe, D. D., Beaven, M. A. (2001) Induction of telomerase activity during development of human mast cells from peripheral blood CD34+ cells: comparisons with tumor mast-cell lines. J. Immunol. 166, 6647-6656.
28. Mano, Y., Shimizu, T., Tanuma, S., Takeda, K. (2000) Synergistic down-regulation of telomerase activity and hTERT mRNA expression by combination of retinoic acid and GM-CSF in human myeloblastic leukemia ML-1 cells. Anticancer Res. 20, 1649-1652.
29. Yin, L., Hubbard, A. K., Giardina, C. (2000) NF-kappa B regulates transcription of the mouse telomerase catalytic subunit. J. Biol. Chem. 275, 36671-36675.
30. Fu, W., Begley, J. G., Killen, M. W., Mattson, M. P. (1999) Anti-apoptotic role of telomerase in pheochromocytoma cells. J. Biol. Chem. 274, 7264-7271.
31. Ghosh, S., May, M. J., Kopp, E. B. (1998) NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16, 225-260.
32. Ouaaz, F., Arron, J., Zheng, Y., Choi, Y., Beg, A. A. (2002) Dendritic cell development and survival require distinct NF-kappaB subunits. Immunity 16, 257-270.
33. Ardeshna, K. M., Pizzey, A. R., Devereux, S., Khwaja, A. (2000) The PI3 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells. Blood 96, 1039-1046.
34. Park, Y., Lee, S. W., Sung, Y. C. (2002) Cutting edge: CpG DNA inhibits dendritic cell apoptosis by up-regulating cellular inhibitor of apoptosis proteins through the phosphatidylinositide-3′-OH kinase pathway. J. Immunol. 168, 5-8.
35. Medema, J. P., Schuurhuis, D. H., Rea, D., van Tongeren, J., de Jong, J., Bres, S. A., Laban, S., Toes, R. E., Toebes, M., Schumacher, T. N., Bladergroen, B. A., Ossendorp, F., Kummer, J. A., Melief, C. J., Offringa, R. (2001) Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: differential modulation by T helper type 1 and type 2 cells. J. Exp. Med. 194, 657-667.
36. Ronchese, F., Hermans, I. F. (2001) Killing of dendritic cells: a life cut short or a purposeful death? J. Exp. Med. 194, F23-F26.
37. Saurwein-Teissl, M., Romani, N., Grubeck-Loebenstein, B. (2000) Dendritic cells in old age-neglected by gerontology? Mech. Ageing Dev. 121, 123-130.
38. Grewe, M. (2001) Chronological ageing and photoageing of dendritic cells. Clin. Exp. Dermatol. 26, 608-612.
39. Lung, T. L., Saurwein-Teissl, M., Parson, W., Schonitzer, D., Grubeck-Loebenstein, B. (2000) Unimpaired dendritic cells can be derived from monocytes in old age and can mobilize residual function in senescent T cells. Vaccine 18, 1606-1612.
40. Globerson, A., Effros, R. B. (2000) Ageing of lymphocytes and lymphocytes in the aged. Immunol. Today 21, 515-521.
41. Weng, N. (2001) Interplay between telomere length and telomerase in human leukocyte differentiation and aging. J. Leukoc. Biol. 70, 861-867.
42. Xunmei, Y., Nikaido, R., Haruyama, T., Watanabe, Y., Iwata, H., Iida, M., Sugimura, H., Yamada, N., Ishikawa, F. (1999) Presence of telomeric G-strand tails in the telomerase catalytic subunit TERT knockout mice. Genes Cells 4, 563-572.