메뉴 건너뛰기




Volumn 4, Issue 10, 1999, Pages 563-572

Presence of telomeric G-strand tails in the telomerase catalytic subunit TERT knockout mice

Author keywords

[No Author keywords available]

Indexed keywords

DNA; RNA DIRECTED DNA POLYMERASE; TELOMERASE;

EID: 6544263270     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.1999.00284.x     Document Type: Article
Times cited : (90)

References (33)
  • 2
    • 0029154735 scopus 로고
    • Functional characterization and developmental regulation of mouse telomerase RNA
    • Blasco, M.A., Funk, W., Villeponteau, B. & Greider, C.W. (1995) Functional characterization and developmental regulation of mouse telomerase RNA. Science 269, 1267-1270.
    • (1995) Science , vol.269 , pp. 1267-1270
    • Blasco, M.A.1    Funk, W.2    Villeponteau, B.3    Greider, C.W.4
  • 3
    • 0030931491 scopus 로고    scopus 로고
    • Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
    • Blasco, M.A., Lee, H.W., Hande, M.P., et al. (1997) Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91, 25-34.
    • (1997) Cell , vol.91 , pp. 25-34
    • Blasco, M.A.1    Lee, H.W.2    Hande, M.P.3
  • 4
    • 0033553516 scopus 로고    scopus 로고
    • p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
    • Chin, L., Artandi, S.E., Shen, Q., et al. (1999) p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell 97, 527-538.
    • (1999) Cell , vol.97 , pp. 527-538
    • Chin, L.1    Artandi, S.E.2    Shen, Q.3
  • 6
    • 0030460748 scopus 로고    scopus 로고
    • Cell cycle-regulated generation of single-stranded G-rich DNA in the absence of telomerase
    • Dionne, I. & Wellinger, R.J. (1996) Cell cycle-regulated generation of single-stranded G-rich DNA in the absence of telomerase. Proc. Nat. Acad. Sci. USA 93, 13902-13907.
    • (1996) Proc. Nat. Acad. Sci. USA , vol.93 , pp. 13902-13907
    • Dionne, I.1    Wellinger, R.J.2
  • 7
    • 0029096515 scopus 로고
    • The RNA component of human telomerase
    • Feng, J., Funk, W.D., Wang, S.S., et al. (1995) The RNA component of human telomerase. Science 269, 1236-1241.
    • (1995) Science , vol.269 , pp. 1236-1241
    • Feng, J.1    Funk, W.D.2    Wang, S.S.3
  • 8
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
    • Greider, C.W. & Blackburn, E.H. (1985) Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43, 405-413.
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 9
    • 0024978857 scopus 로고
    • A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
    • Greider, C.W. & Blackburn, E.H. (1989) A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature 337, 331-337.
    • (1989) Nature , vol.337 , pp. 331-337
    • Greider, C.W.1    Blackburn, E.H.2
  • 10
    • 0033553536 scopus 로고    scopus 로고
    • Mammalian telomeres end in a large duplex loop
    • Griffith, J.D., Comeau, L., Rosenfield, S., et al. (1999) Mammalian telomeres end in a large duplex loop. Cell 97, 503-514.
    • (1999) Cell , vol.97 , pp. 503-514
    • Griffith, J.D.1    Comeau, L.2    Rosenfield, S.3
  • 11
    • 0031036350 scopus 로고    scopus 로고
    • A mammalian telomerase-associated protein
    • Harrington, L., McPhail, T., Mar, V., et al. (1997) A mammalian telomerase-associated protein. Science 275, 973-977.
    • (1997) Science , vol.275 , pp. 973-977
    • Harrington, L.1    McPhail, T.2    Mar, V.3
  • 12
    • 0027258140 scopus 로고
    • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
    • Ishibashi, S., Brown, M.S., Goldstein, J.L., Gerard, R.D., Hammer, R.E. & Herz, J. (1993) Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J. Clin. Invest. 92, 883-893.
    • (1993) J. Clin. Invest. , vol.92 , pp. 883-893
    • Ishibashi, S.1    Brown, M.S.2    Goldstein, J.L.3    Gerard, R.D.4    Hammer, R.E.5    Herz, J.6
  • 13
    • 0025029030 scopus 로고
    • Hypervariable ultra-long telomeres in mice
    • Kipling, D. & Cooke, H.J. (1990) Hypervariable ultra-long telomeres in mice. Nature 347, 400-402.
    • (1990) Nature , vol.347 , pp. 400-402
    • Kipling, D.1    Cooke, H.J.2
  • 14
    • 0019568388 scopus 로고
    • All gene-sized DNA molecules in four species of hypotrichs have the same terminal sequence and an unusual 3′ terminus
    • Klobutcher, L.A., Swanton, M.T., Donini, P. & Prescott, D.M. (1981) All gene-sized DNA molecules in four species of hypotrichs have the same terminal sequence and an unusual 3′ terminus. Proc. Natl. Acad. Sci. USA 78, 3015-3019.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 3015-3019
    • Klobutcher, L.A.1    Swanton, M.T.2    Donini, P.3    Prescott, D.M.4
  • 15
    • 0032499210 scopus 로고    scopus 로고
    • Essential role of mouse telomerase in highly proliferative organs
    • Lee, H.W., Blasco, M.A., Gottlieb, G.J., et al. (1998) Essential role of mouse telomerase in highly proliferative organs. Nature 392, 569-574.
    • (1998) Nature , vol.392 , pp. 569-574
    • Lee, H.W.1    Blasco, M.A.2    Gottlieb, G.J.3
  • 17
    • 0031000884 scopus 로고    scopus 로고
    • Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
    • Makarov, V.L., Hirose, Y. & Langmore, J.P. (1997) Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening. Cell 88, 657-666.
    • (1997) Cell , vol.88 , pp. 657-666
    • Makarov, V.L.1    Hirose, Y.2    Langmore, J.P.3
  • 18
    • 0030982721 scopus 로고    scopus 로고
    • The terminal DNA structure of mammalian chromosomes
    • McElligott, R. & Wellinger, R.J. (1997) The terminal DNA structure of mammalian chromosomes. EMBO J. 16, 3705-3714.
    • (1997) EMBO J , vol.16 , pp. 3705-3714
    • McElligott, R.1    Wellinger, R.J.2
  • 19
    • 0030745448 scopus 로고    scopus 로고
    • hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
    • Meyerson, M., Counter, C.M., Eaton, E.N., et al. (1997) hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell 90, 785-795.
    • (1997) Cell , vol.90 , pp. 785-795
    • Meyerson, M.1    Counter, C.M.2    Eaton, E.N.3
  • 20
    • 0032961170 scopus 로고    scopus 로고
    • A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3′ end
    • Mitchell, J.R., Cheng, J. & Collins, K. (1999) A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3′ end. Mol. Cell. Biol. 19, 567-576.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 567-576
    • Mitchell, J.R.1    Cheng, J.2    Collins, K.3
  • 21
    • 0030898989 scopus 로고    scopus 로고
    • TLP1: A gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family
    • Nakayama, J., Saito, M., Nakamura, H., Matsuura, A. & Ishikawa, F. (1997) TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family. Cell 88, 875-884.
    • (1997) Cell , vol.88 , pp. 875-884
    • Nakayama, J.1    Saito, M.2    Nakamura, H.3    Matsuura, A.4    Ishikawa, F.5
  • 22
    • 17344363008 scopus 로고    scopus 로고
    • Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
    • Nakayama, J., Tahara, H., Tahara, E., et al. (1998) Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas. Nature Genet. 18, 65-68.
    • (1998) Nature Genet. , vol.18 , pp. 65-68
    • Nakayama, J.1    Tahara, H.2    Tahara, E.3
  • 23
    • 0032554797 scopus 로고    scopus 로고
    • Telomere maintenance is dependent on activities required for end repair of double-strand breaks
    • Nugent, C.I., Bosco, G., Ross, L.O., et al. (1998) Telomere maintenance is dependent on activities required for end repair of double-strand breaks. Curr. Biol. 8, 657-660.
    • (1998) Curr. Biol. , vol.8 , pp. 657-660
    • Nugent, C.I.1    Bosco, G.2    Ross, L.O.3
  • 24
    • 0030781067 scopus 로고    scopus 로고
    • Functionally interacting telomerase RNAs in the yeast telomerase complex
    • Prescott, J. & Blackburn, E.H. (1997) Functionally interacting telomerase RNAs in the yeast telomerase complex. Genes Dev. 11, 2790-2800.
    • (1997) Genes Dev. , vol.11 , pp. 2790-2800
    • Prescott, J.1    Blackburn, E.H.2
  • 25
    • 0031010342 scopus 로고    scopus 로고
    • A survey of telomerase activity in human cancer
    • Shay, J. W. & Bacchetti, S. (1997) A survey of telomerase activity in human cancer. Eur. J. Cancer 33, 787-791.
    • (1997) Eur. J. Cancer , vol.33 , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.2
  • 26
  • 27
    • 0029802285 scopus 로고    scopus 로고
    • A novel quantitative 'stretch PCR assay', that detects a dramatic increase in telomerase activity during the progression of myeloid leukemias
    • Tatematsu, K., Nakayama, J., Danbara, M., et al. (1996) A novel quantitative 'stretch PCR assay', that detects a dramatic increase in telomerase activity during the progression of myeloid leukemias. Oncogene 13, 2265-2274.
    • (1996) Oncogene , vol.13 , pp. 2265-2274
    • Tatematsu, K.1    Nakayama, J.2    Danbara, M.3
  • 28
    • 0030659644 scopus 로고    scopus 로고
    • Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT
    • Weinrich, S.L., Pruzan, R., Ma, L., et al. (1997) Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT. Nature Genet. 17, 498-502.
    • (1997) Nature Genet. , vol.17 , pp. 498-502
    • Weinrich, S.L.1    Pruzan, R.2    Ma, L.3
  • 29
    • 0029953557 scopus 로고    scopus 로고
    • Evidence for a new step in telomere maintenance
    • Wellinger, R.J., Ethier, K., Labrecque, P. & Zakian, V.A. (1996) Evidence for a new step in telomere maintenance. Cell 85, 423-433.
    • (1996) Cell , vol.85 , pp. 423-433
    • Wellinger, R.J.1    Ethier, K.2    Labrecque, P.3    Zakian, V.A.4
  • 30
    • 0027509950 scopus 로고
    • Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase
    • Wellinger, R.J., Wolf, A.J. & Zakian, V.A. (1993) Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase. Cell 72, 51-60.
    • (1993) Cell , vol.72 , pp. 51-60
    • Wellinger, R.J.1    Wolf, A.J.2    Zakian, V.A.3
  • 31
    • 0030731928 scopus 로고    scopus 로고
    • Normal human chromosomes have long G-rich telomeric overhangs at one end
    • Wright, W.E., Tesmer, V.M., Huffman, K.E., Levene, S.D. & Shay, J.W. (1997) Normal human chromosomes have long G-rich telomeric overhangs at one end. Genes Dev. 11, 2801-2809.
    • (1997) Genes Dev. , vol.11 , pp. 2801-2809
    • Wright, W.E.1    Tesmer, V.M.2    Huffman, K.E.3    Levene, S.D.4    Shay, J.W.5
  • 32
    • 0033049185 scopus 로고    scopus 로고
    • Both transcriptional and posttranscriptional mechanisms regulate human telomerase template RNA levels
    • Yi, X., Tesmer, V.M., Savre-Train, I., Shay, J.W. & Wright, W.E. (1999) Both transcriptional and posttranscriptional mechanisms regulate human telomerase template RNA levels. Mol. Cell. Biol. 19, 3989-3997.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 3989-3997
    • Yi, X.1    Tesmer, V.M.2    Savre-Train, I.3    Shay, J.W.4    Wright, W.E.5
  • 33
    • 0025279059 scopus 로고
    • In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs
    • Yu, G.L., Bradley, J.D., Attardi, L.D. & Blackburn, E.H. (1990) In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs. Nature 344, 126-132.
    • (1990) Nature , vol.344 , pp. 126-132
    • Yu, G.L.1    Bradley, J.D.2    Attardi, L.D.3    Blackburn, E.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.