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Volumn 97, Issue 5, 2003, Pages 439-451

Point mutations in the pfcrt and pfmdr-1 genes of Plasmodium falciparum and clinical response to chloroquine, among malaria patients from Nigeria

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE;

EID: 0041346177     PISSN: 00034983     EISSN: None     Source Type: Journal    
DOI: 10.1179/000349803235002489     Document Type: Article
Times cited : (51)

References (46)
  • 3
    • 0027056692 scopus 로고
    • Chloroquine-resistant Plasmodium falciparum isolates from the Sudan lack two mutations in the pfmdr1 gene thought to be associated with chloroquine resistance
    • Awad-El-Kariem, F. M., Miles, M. A. & Warhurst, D. C. (1992). Chloroquine-resistant Plasmodium falciparum isolates from the Sudan lack two mutations in the pfmdr1 gene thought to be associated with chloroquine resistance. Transactions of the Royal Society of Tropical Medicine and Hygiene, 86, 587-589.
    • (1992) Transactions of the Royal Society of Tropical Medicine and Hygiene , vol.86 , pp. 587-589
    • Awad-El-Kariem, F.M.1    Miles, M.A.2    Warhurst, D.C.3
  • 5
    • 0035873715 scopus 로고    scopus 로고
    • High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance gene pfmdr1
    • Babiker, H. A., Pringle, S. J., Abdel-Muhsin, A., Mackinnon, M., Hunt, P. & Walliker, D. (2001). High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance gene pfmdr1. Journal of Infectious Diseases, 183, 1535-1538.
    • (2001) Journal of Infectious Diseases , vol.183 , pp. 1535-1538
    • Babiker, H.A.1    Pringle, S.J.2    Abdel-Muhsin, A.3    Mackinnon, M.4    Hunt, P.5    Walliker, D.6
  • 6
    • 0031724298 scopus 로고    scopus 로고
    • Molecular epidemiology of malaria in Yaounde, Cameroon. III. Analysis of chloroquine resistance and point mutations in the multidrug resistance 1 (pfmdr 1) gene of Plasmodium falciparum
    • Basco, L. K. & Ringwald, P. (1998). Molecular epidemiology of malaria in Yaounde, Cameroon. III. Analysis of chloroquine resistance and point mutations in the multidrug resistance 1 (pfmdr 1) gene of Plasmodium falciparum. American Journal of Tropical Medicine and Hygiene, 59, 577-581.
    • (1998) American Journal of Tropical Medicine and Hygiene , vol.59 , pp. 577-581
    • Basco, L.K.1    Ringwald, P.2
  • 7
    • 0035876910 scopus 로고    scopus 로고
    • Analysis of the key pfcrt point mutation and in vitro and in vivo response to chloroquine in Yaounde, Cameroon
    • Basco, L. K. & Ringwald, P. (2001). Analysis of the key pfcrt point mutation and in vitro and in vivo response to chloroquine in Yaounde, Cameroon. Journal of Infectious Diseases, 183, 1828-1831.
    • (2001) Journal of Infectious Diseases , vol.183 , pp. 1828-1831
    • Basco, L.K.1    Ringwald, P.2
  • 8
    • 0029586497 scopus 로고
    • Analysis of pfmdr1 and drug susceptibility in fresh isolates of Plasmodium falciparum from sub-Saharan Africa
    • Basco, L. K., le Bras, J., Rhoades, Z. & Wilson, C. M. (1995). Analysis of pfmdr1 and drug susceptibility in fresh isolates of Plasmodium falciparum from sub-Saharan Africa. Molecular and Biochemical Parasitology, 74, 157-166.
    • (1995) Molecular and Biochemical Parasitology , vol.74 , pp. 157-166
    • Basco, L.K.1    Le Bras, J.2    Rhoades, Z.3    Wilson, C.M.4
  • 9
    • 0029953754 scopus 로고    scopus 로고
    • Plasmodium falciparum: Molecular characterization of multidrug-resistant Cambodian isolates
    • Basco, L. K., de Pecoulas, P. E., le Bras, J. & Wilson, C. M. (1996). Plasmodium falciparum: molecular characterization of multidrug-resistant Cambodian isolates. Experimental Parasitology, 82, 97-103.
    • (1996) Experimental Parasitology , vol.82 , pp. 97-103
    • Basco, L.K.1    De Pecoulas, P.E.2    Le Bras, J.3    Wilson, C.M.4
  • 11
    • 0034899821 scopus 로고    scopus 로고
    • Conservation of a novel vacuolar transporter in Plasmodium species and its central role in chloroquine resistance of P. falciparum
    • Carlton, J. M., Fidock, D. A., Djimdé, A., Plowe, C. V. & Wellems, T. E. (2001). Conservation of a novel vacuolar transporter in Plasmodium species and its central role in chloroquine resistance of P. falciparum. Current Opinion in Microbiology, 4, 415-420.
    • (2001) Current Opinion in Microbiology , vol.4 , pp. 415-420
    • Carlton, J.M.1    Fidock, D.A.2    Djimdé, A.3    Plowe, C.V.4    Wellems, T.E.5
  • 13
    • 0035341936 scopus 로고    scopus 로고
    • Polymorphisms in the Plasmodium falciparum pfcrt and pfmdr-1 genes and clinical response to chloroquine in Kampala, Uganda
    • Dorsey, G., Kamya, M. R., Singh, A. & Rosenthal, P. J. (2001). Polymorphisms in the Plasmodium falciparum pfcrt and pfmdr-1 genes and clinical response to chloroquine in Kampala, Uganda. Journal of Infectious Diseases, 183, 1417-1420.
    • (2001) Journal of Infectious Diseases , vol.183 , pp. 1417-1420
    • Dorsey, G.1    Kamya, M.R.2    Singh, A.3    Rosenthal, P.J.4
  • 14
    • 0030896558 scopus 로고    scopus 로고
    • Evidence for selection for the tyrosine-86 allele of the pfmdr 1 gene of Plasmodium falciparum by chloroquine and amodiaquine
    • Durasingh, M. T., Drakeley, C. J., Muller, O., Bailey, R., Snounou, G., Targett, G. A., Greenwood, B. M. & Warhurst, D. C. (1997). Evidence for selection for the tyrosine-86 allele of the pfmdr 1 gene of Plasmodium falciparum by chloroquine and amodiaquine. Parasitology, 114, 205-211.
    • (1997) Parasitology , vol.114 , pp. 205-211
    • Durasingh, M.T.1    Drakeley, C.J.2    Muller, O.3    Bailey, R.4    Snounou, G.5    Targett, G.A.6    Greenwood, B.M.7    Warhurst, D.C.8
  • 16
    • 0033827905 scopus 로고    scopus 로고
    • Allelic modifications of the cg2 and cg1 genes do not alter the chloroquine response of drug-resistant Plasmodium falciparum
    • Fidock, D. A., Nomura, T., Cooper, R. A., Su, X., Talley, A. K. & Wellems, T. E. (2000a). Allelic modifications of the cg2 and cg1 genes do not alter the chloroquine response of drug-resistant Plasmodium falciparum. Molecular and Biochemical Parasitology, 110, 1-10.
    • (2000) Molecular and Biochemical Parasitology , vol.110 , pp. 1-10
    • Fidock, D.A.1    Nomura, T.2    Cooper, R.A.3    Su, X.4    Talley, A.K.5    Wellems, T.E.6
  • 19
    • 0024338609 scopus 로고
    • Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum
    • Foote, S. J., Thompson, J. K., Cowman, A. F. & Kemp, D. J. (1989). Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum. Cell, 57, 921-930.
    • (1989) Cell , vol.57 , pp. 921-930
    • Foote, S.J.1    Thompson, J.K.2    Cowman, A.F.3    Kemp, D.J.4
  • 20
    • 0025269612 scopus 로고
    • Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum
    • Foote, S. J., Kyle, D. E., Martin, R. K., Oduola, A. M., Forsyth, K., Kemp, D. J. & Cowman, A. F. (1990). Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum. Nature, 345, 255-258.
    • (1990) Nature , vol.345 , pp. 255-258
    • Foote, S.J.1    Kyle, D.E.2    Martin, R.K.3    Oduola, A.M.4    Forsyth, K.5    Kemp, D.J.6    Cowman, A.F.7
  • 21
    • 0026610906 scopus 로고
    • Rapid detection of pfmdr1 mutations in chloroquine-resistant Plasmodium falciparum malaria by polymerase chain reaction analysis of blood spots
    • Frean, J. A., El Kariem, F. M., Warhurst, D. C. & Miles, M. A. (1992). Rapid detection of pfmdr1 mutations in chloroquine-resistant Plasmodium falciparum malaria by polymerase chain reaction analysis of blood spots. Transactions of the Royal Society of Tropical Medicine and Hygiene, 86, 29-30.
    • (1992) Transactions of the Royal Society of Tropical Medicine and Hygiene , vol.86 , pp. 29-30
    • Frean, J.A.1    El Kariem, F.M.2    Warhurst, D.C.3    Miles, M.A.4
  • 22
    • 0030221643 scopus 로고    scopus 로고
    • Single-strand conformational polymorphism analysis differentiates Plasmodium falciparum treatment failures from re-infections
    • Kain, K. C., Craig, A. A. & Ohrt, C. (1996). Single-strand conformational polymorphism analysis differentiates Plasmodium falciparum treatment failures from re-infections. Molecular and Biochemical Parasitology, 79, 167-175.
    • (1996) Molecular and Biochemical Parasitology , vol.79 , pp. 167-175
    • Kain, K.C.1    Craig, A.A.2    Ohrt, C.3
  • 24
    • 0034808372 scopus 로고    scopus 로고
    • The T76 mutation in the pfcrt gene of Plasmodium falciparum and clinical chloroquine resistance phenotypes in Papua, Indonesia
    • Maguire, J. D., Susanti, A. I., Krisin, Sismadi, P., Fryauff, D. J. & Baird, J. K. (2001). The T76 mutation in the pfcrt gene of Plasmodium falciparum and clinical chloroquine resistance phenotypes in Papua, Indonesia. Annals of Tropical Medicine and Parasitology, 95, 559-572.
    • (2001) Annals of Tropical Medicine and Parasitology , vol.95 , pp. 559-572
    • Maguire, J.D.1    Susanti, A.I.2    Krisin3    Sismadi, P.4    Fryauff, D.J.5    Baird, J.K.6
  • 25
    • 0035341841 scopus 로고    scopus 로고
    • Prevalence of the K76T mutation in the putative Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene and its relation to chloroquine resistance in Mozambique
    • Mayor, A. G., Gomez-Olive, X., Aponte, J. J., Casimiro, S., Mabunda, S., Dgedge, M., Barreto, A. & Alonso, P. L. (2001). Prevalence of the K76T mutation in the putative Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene and its relation to chloroquine resistance in Mozambique. Journal of Infectious Diseases, 183, 1413-1416.
    • (2001) Journal of Infectious Diseases , vol.183 , pp. 1413-1416
    • Mayor, A.G.1    Gomez-Olive, X.2    Aponte, J.J.3    Casimiro, S.4    Mabunda, S.5    Dgedge, M.6    Barreto, A.7    Alonso, P.L.8
  • 27
    • 0023921794 scopus 로고
    • Plasmodium falciparum: Cloning by single-erythrocyte micromanipulation and heterogeneity in vitro
    • Oduola, A. M., Weatherly, N. F., Bowdre, J. H. & Desjardins, R. E. (1988). Plasmodium falciparum: cloning by single-erythrocyte micromanipulation and heterogeneity in vitro. Experimental Parasitology, 66, 86-95.
    • (1988) Experimental Parasitology , vol.66 , pp. 86-95
    • Oduola, A.M.1    Weatherly, N.F.2    Bowdre, J.H.3    Desjardins, R.E.4
  • 28
    • 0030772441 scopus 로고    scopus 로고
    • Distinguishing Plasmodium falciparum treatment failures from reinfections by restriction fragment length polymorphism and polymerase chain reaction genotyping
    • Ohrt, C., Mirabelli-Primdahl, L., Karnasuta, C., Chantakulkij, S. & Kain, K. C. (1997). Distinguishing Plasmodium falciparum treatment failures from reinfections by restriction fragment length polymorphism and polymerase chain reaction genotyping. American Journal of Tropical Medicine and Hygiene, 57, 430-437.
    • (1997) American Journal of Tropical Medicine and Hygiene , vol.57 , pp. 430-437
    • Ohrt, C.1    Mirabelli-Primdahl, L.2    Karnasuta, C.3    Chantakulkij, S.4    Kain, K.C.5
  • 29
    • 0035198972 scopus 로고    scopus 로고
    • Plasmodium falciparum in Kenya: High prevalence of drug-resistance-associated polymorphisms in hospital admissions with severe malaria in an epidemic area
    • Omar, S. A., Adagu, I. S., Gump, D. W., Ndaru, N. P. & Warhurst, D. C. (2001). Plasmodium falciparum in Kenya: high prevalence of drug-resistance-associated polymorphisms in hospital admissions with severe malaria in an epidemic area. Annals of Tropical Medicine and Parasitology, 95, 661-669.
    • (2001) Annals of Tropical Medicine and Parasitology , vol.95 , pp. 661-669
    • Omar, S.A.1    Adagu, I.S.2    Gump, D.W.3    Ndaru, N.P.4    Warhurst, D.C.5
  • 31
    • 0029050608 scopus 로고
    • Pyrimethamine and proguanil resistance-conferring mutations in Plasmodium falciparum dihydrofolate reductase: Polymerase chain reaction methods for surveillance in Africa
    • Plowe, C. V., Djimdé, A., Bouare, M., Doumbo, O. & Wellems, T. E. (1995). Pyrimethamine and proguanil resistance-conferring mutations in Plasmodium falciparum dihydrofolate reductase: polymerase chain reaction methods for surveillance in Africa. American Journal of Tropical Medicine and Hygiene, 52, 565-568.
    • (1995) American Journal of Tropical Medicine and Hygiene , vol.52 , pp. 565-568
    • Plowe, C.V.1    Djimdé, A.2    Bouare, M.3    Doumbo, O.4    Wellems, T.E.5
  • 32
    • 0031608778 scopus 로고    scopus 로고
    • pfmdr1 Asn1042Asp and Asp1246Tyr polymorphisms, thought to be associated with chloroquine resistance, are present in chloroquine-resistant and -sensitive Brazilian field isolates of Plasmodium falciparum
    • Povoa, M. M., Adagu, I. S., Oliveira, S. G., Machado, R. L., Miles, M. A. & Warhurst, D. C. (1998). pfmdr1 Asn1042Asp and Asp1246Tyr polymorphisms, thought to be associated with chloroquine resistance, are present in chloroquine-resistant and -sensitive Brazilian field isolates of Plasmodium falciparum. Experimenral Parasitology, 88, 64-68.
    • (1998) Experimenral Parasitology , vol.88 , pp. 64-68
    • Povoa, M.M.1    Adagu, I.S.2    Oliveira, S.G.3    Machado, R.L.4    Miles, M.A.5    Warhurst, D.C.6
  • 34
    • 0034708162 scopus 로고    scopus 로고
    • pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum
    • Reed, M. B., Saliba, K. J., Caruana, S. R., Kirk, K. & Cowman, A. F. (2000). pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum. Nature, 403, 906-909.
    • (2000) Nature , vol.403 , pp. 906-909
    • Reed, M.B.1    Saliba, K.J.2    Caruana, S.R.3    Kirk, K.4    Cowman, A.F.5
  • 35
    • 0035217943 scopus 로고    scopus 로고
    • Allelic variation in the cg2 gene does not correlate with chloroquine resistance among Indian Plasmodium falciparum isolates
    • Sharma, I., Aneja, M. K., Biswas, S., Dev, V., Ansari, M. A., Pasha, S. T. & Sharma, Y. D. (2001). Allelic variation in the cg2 gene does not correlate with chloroquine resistance among Indian Plasmodium falciparum isolates. International Journal for Parasitology, 31, 1669-1672.
    • (2001) International Journal for Parasitology , vol.31 , pp. 1669-1672
    • Sharma, I.1    Aneja, M.K.2    Biswas, S.3    Dev, V.4    Ansari, M.A.5    Pasha, S.T.6    Sharma, Y.D.7
  • 38
    • 0031589733 scopus 로고    scopus 로고
    • Complex polymorphisms in an approximately 330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa
    • Su, X., Kirkman, L. A., Fujioka, H. & Wellems, T. E. (1997). Complex polymorphisms in an approximately 330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa. Cell, 91, 593-603.
    • (1997) Cell , vol.91 , pp. 593-603
    • Su, X.1    Kirkman, L.A.2    Fujioka, H.3    Wellems, T.E.4
  • 40
    • 0035945673 scopus 로고    scopus 로고
    • A molecular marker for chloroquine-resistant falciparum malaria
    • Warhurst, D. C. (2001). A molecular marker for chloroquine-resistant falciparum malaria. New England Journal of Medicine, 344, 299-302.
    • (2001) New England Journal of Medicine , vol.344 , pp. 299-302
    • Warhurst, D.C.1
  • 42
    • 0024356582 scopus 로고
    • Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum
    • Wilson, C. M., Serrano, A. E., Wasley, A., Bogenschutz, M. P., Shankar, A. H. & Wirth, D. F. (1989). Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum. Science, 244, 1184-1186.
    • (1989) Science , vol.244 , pp. 1184-1186
    • Wilson, C.M.1    Serrano, A.E.2    Wasley, A.3    Bogenschutz, M.P.4    Shankar, A.H.5    Wirth, D.F.6
  • 46


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