Role of leptin as an immunomodulator of blood mononuclear cells: Mechanisms of action

Clinical and Experimental Immunology

Volumn 133, Issue 1, 2003, Pages 11-19

  Sánchez Margalet, Víctor ^a   Martin Romero C ^a   Santos Alvarez, J ^a   Goberna, R ^a   Najib, S ^a   Gonzalez Yanes, C ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN MACARENA   (Spain)

Author keywords

Cell activation; Cytokine; Leptin; Leptin receptor; Lymphocytes; Obesity; PBMC; Th1 response

Indexed keywords

CYTOKINE; IMMUNOMODULATING AGENT; INSULIN RECEPTOR SUBSTRATE 1; JANUS KINASE; LEPTIN; LEPTIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SAM68; RNA BINDING PROTEIN; STAT PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; BLOOD CELL; BODY WEIGHT; CELL ACTIVATION; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; CYTOKINE PRODUCTION; ENERGY EXPENDITURE; FOOD INTAKE; HEMATOPOIETIC TISSUE; HORMONAL REGULATION; HORMONE ACTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPOTHESIS; IMMUNE SYSTEM; IMMUNOREGULATION; INFLAMMATION; LYMPHOCYTE ACTIVATION; MONOCYTE; MONONUCLEAR CELL; NONHUMAN; NUTRITIONAL STATUS; OBESITY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REVIEW; SERUM; SIGNAL TRANSDUCTION; TH1 CELL; TISSUE DISTRIBUTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADIPOCYTES; APOPTOSIS; AUTOIMMUNE DISEASES; CELLS, CULTURED; CYTOKINES; HUMANS; JANUS KINASE 1; LEPTIN; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; MAP KINASE SIGNALING SYSTEM; NUTRITIONAL STATUS; OBESITY; PROTEIN ISOFORMS; PROTEIN-TYROSINE KINASES; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; TH1 CELLS;

EID: 0038723695     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2003.02190.x     Document Type: Review

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