Bisquaternary dimers of strychnine and brucine. A new class of potent enhancers of antagonist binding to muscarinic M2 receptors

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 12, 2003, Pages 2627-2634

  Zlotos, D P ^a   Buller, S ^b   Holzgrabe, U ^a   Mohr, K ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

(1,6 HEXYLENE) 4,4' DIBRUCINIUM DIBROMIDE; (1,6 HEXYLENE) 4,4' DISTRYCHNINIUM DIBROMIDE; (1,7 HEPTYLENE) 4,4' BIS(19,20 DIHYDROSTRYCHNINIUM)DIBROMIDE; (1,7 HEPTYLENE) 4,4' BIS(22 OXIMINOBRUCINIUM)DIBROMIDE; (1,7 HEPTYLENE) 4,4' DIBRUCINIUM DIBROMIDE; (1,7 HEPTYLENE) 4,4' DISTRYCHNINIUM DIBROMIDE; (1,8 OCTYLENE) 4,4' DIBRUCINIUM DIBROMIDE; (1,8 OCTYLENE) 4,4' DISTRYCHNINIUM DIBROMIDE; BROMINE DERIVATIVE; BRUCINE; CHOLINERGIC RECEPTOR; DIMER; METHYLSCOPOLAMINE; MONOMER; MUSCARINIC M2 RECEPTOR; STRYCHNINE; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DISSOCIATION; DRUG EFFECT; DRUG POTENCY; DRUG POTENTIATION; DRUG PROTEIN BINDING; DRUG SPECIFICITY; DRUG SYNTHESIS; NONHUMAN; STRUCTURE ACTIVITY RELATION; SWINE;

STRYCHNOS TOXIFERA; SUIDAE;

EID: 0038334905     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(03)00146-9     Document Type: Article

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